SUPERFAMILY 1.75 HMM library and genome assignments server

Phenotypic Abnormality (PA): Abnormality of connective tissue

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   Phenotypic abnormality [HP:0000118] <21>
0:   Abnormality of connective tissue [HP:0003549] <11>(15|20) (16|9|4)
- 1:   Flexion contracture [HP:0001371] <9>(5|4) (5|4|0)
- 1:   Abnormality of adipose tissue [HP:0009124] <8>(1|2) (1|1|1)
- 1:   Scarring [HP:0100699] <4>(1|2) (1|1|2)
- 1:   Hernia [HP:0100790] <3>(5|6) (5|0|0)
- 1:   Abnormality of Sharpey fibers [HP:0100685] <2>(0|0) (0|0|0)
- 1:   Abnormality of mast cells [HP:0100494] <1>(0|0) (0|0|0)
- 1:   Abnormality of the fascia [HP:0100536] <1>(0|0) (0|0|0)
- 1:   Cellulitis [HP:0100658] <1>(1|1) (1|0|0)
- 1:   Connective tissue nevi [HP:0100898] <1>(0|0) (0|0|0)
- 1:   Increased connective tissue [HP:0009025] <1>(0|0) (0|0|0)
- 1:   Congenital mesoblastic nephroma [HP:0100881](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Troponin coil-coiled subunits0Direct
Glycerol-3-phosphate (1)-acyltransferase0Direct
BRK domain-like0Direct
FKBP-like0Direct
LEM domain0Direct
Tropomyosin0.002956Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.003024Inherited
Nicotinic receptor ligand binding domain-like0.003024Inherited
CalX-like0.006683Inherited
SET domain0.008187Inherited
FnI-like domain0.01315Inherited
Myosin rod fragments0.03571Inherited
Snake toxin-like0.2015Inherited
vWA-like0.2547Inherited
SH3-domain0.7109Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
LEM domain0Direct
ZZ domain0Direct
BRK domain-like0Direct
Troponin T0Direct
FKBP immunophilin/proline isomerase0Direct
XPF/Rad1/Mus81 nuclease0Direct
Laminin-type module0.0006942Direct
VWC domain0.001373Inherited
Tropomyosin0.001939Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.002007Inherited
Nicotinic receptor ligand binding domain-like0.002007Inherited
CalX-beta domain0.004549Inherited
LIM domain0.004549Inherited
Laminin G-like module0.01195Inherited
Histone lysine methyltransferases0.01591Inherited
Myosin rod fragments0.02773Inherited
Arylsulfatase0.06011Inherited
EGF-type module0.07905Inherited
Integrin A (or I) domain0.09851Inherited
SH3-domain0.6939Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
LEM domain0Direct
FKBP-like0Direct
Troponin coil-coiled subunits0Direct
BRK domain-like0Direct
Glycerol-3-phosphate (1)-acyltransferase0Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0007194Direct
Tropomyosin0.001794Inherited
Nicotinic receptor ligand binding domain-like0.001841Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.001841Inherited
CalX-like0.004359Inherited
SET domain0.005416Inherited
FnI-like domain0.009056Inherited
Myosin rod fragments0.02683Inherited
Snake toxin-like0.1731Inherited
vWA-like0.2236Inherited
SH3-domain0.6782Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0003891Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.001425Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.001841Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.02683Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.0403Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.0403Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48726,49265,48726
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.004359Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.004359Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.005432Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)