SUPERFAMILY 1.75 HMM library and genome assignments server

Phenotypic Abnormality (PA): Neoplasm

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   Phenotypic abnormality [HP:0000118] <21>
0:   Neoplasm [HP:0002664] <2>(10|11) (12|4|2)
- 1:   Neoplasm by anatomical site [HP:0011793] <24>(7|7) (10|2|2)
- 1:   Neoplasm by histology [HP:0011792] <5>(4|4) (4|1|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Protein kinase-like (PK-like)0.0000002357Direct
FYVE/PHD zinc finger0.004516Inherited
Ubiquitin-like0.01416Inherited
Intermediate filament protein, coiled coil region0.01633Inherited
Ribosomal protein S5 domain 2-like0.02958Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.045Inherited
SET domain0.07236Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.0826Inherited
Cysteine proteinases0.179Inherited
Ankyrin repeat0.2036Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
DNA gyrase/MutL, second domain0Direct
DNA gyrase/MutL, N-terminal domain0Direct
ets domain0Direct
Protein kinases, catalytic subunit0.000001245Direct
PHD domain0.0006331Direct
Tandem AAA-ATPase domain0.0008424Direct
Intermediate filament protein, coiled coil region0.01511Inherited
Histone lysine methyltransferases0.03858Inherited
I set domains0.2006Inherited
Ankyrin repeat0.2006Inherited
G proteins0.5657Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Protein kinase-like (PK-like)0.00000009383Direct
FYVE/PHD zinc finger0.002848Inherited
Ubiquitin-like0.009864Inherited
Intermediate filament protein, coiled coil region0.01147Inherited
Ribosomal protein S5 domain 2-like0.02184Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.03453Inherited
SET domain0.05761Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.06625Inherited
ARM repeat0.1322Inherited
Cysteine proteinases0.1521Inherited
Ankyrin repeat0.1752Inherited
Homeodomain-like0.3604Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.03557Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.01153Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.03766Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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