SUPERFAMILY 1.75 HMM library and genome assignments server

Phenotypic Abnormality (PA): Abnormality of the respiratory system

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   Phenotypic abnormality [HP:0000118] <21>
0:   Abnormality of the respiratory system [HP:0002086] <2>(20|25) (21|11|7)
- 1:   Functional respiratory abnormality [HP:0002795] <13>(5|8) (6|2|0)
- 1:   Abnormal respiratory system morphology [HP:0012252] <5>(16|20) (17|8|5)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Transcription factor STAT-4 N-domain0Direct
STAT0Direct
Saposin0Direct
GroEL equatorial domain-like0.01581Inherited
CalX-like0.01581Inherited
(Trans)glycosidases0.01633Inherited
PX domain0.03779Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.0439Inherited
Nicotinic receptor ligand binding domain-like0.0439Inherited
GLA-domain0.08911Inherited
TB module/8-cys domain0.09401Inherited
Growth factor receptor domain0.1858Inherited
EGF/Laminin0.1902Inherited
TNF receptor-like0.2015Inherited
Globin-like0.238Inherited
SH3-domain0.3033Inherited
ABC transporter transmembrane region0.4587Inherited
Intermediate filament protein, coiled coil region0.4827Inherited
vWA-like0.6232Inherited
Ubiquitin-like0.7583Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Prefoldin0Direct
Filamin repeat (rod domain)0Direct
ZZ domain0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
STAT DNA-binding domain0Direct
STAT0Direct
Transcription factor STAT-4 N-domain0Direct
beta-glycanases0Direct
Tetratricopeptide repeat (TPR)0.001143Inherited
CalX-beta domain0.01012Inherited
Laminin-type module0.01456Inherited
PX domain0.0264Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.02992Inherited
Nicotinic receptor ligand binding domain-like0.02992Inherited
Arylsulfatase0.03223Inherited
GLA-domain0.06555Inherited
TB module/8-cys domain0.07035Inherited
Calponin-homology domain, CH-domain0.09315Inherited
WD40-repeat0.1742Inherited
ABC transporter ATPase domain-like0.178Inherited
Globins0.1958Inherited
SH3-domain0.2443Inherited
Integrin A (or I) domain0.3437Inherited
Intermediate filament protein, coiled coil region0.4191Inherited
ABC transporter transmembrane region0.6242Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
STAT0Direct
Saposin0Direct
Transcription factor STAT-4 N-domain0Direct
CalX-like0.0111Inherited
GroEL equatorial domain-like0.0111Inherited
(Trans)glycosidases0.01148Inherited
PX domain0.02847Inherited
Nicotinic receptor ligand binding domain-like0.03355Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.03355Inherited
GLA-domain0.07184Inherited
TB module/8-cys domain0.07622Inherited
Calponin-homology domain, CH-domain0.1032Inherited
Growth factor receptor domain0.1582Inherited
EGF/Laminin0.1624Inherited
TNF receptor-like0.1731Inherited
Globin-like0.2077Inherited
SH3-domain0.2704Inherited
ABC transporter transmembrane region0.4235Inherited
Intermediate filament protein, coiled coil region0.4472Inherited
vWA-like0.5886Inherited
Ubiquitin-like0.7267Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0Direct
    57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.02847Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.03355Inherited
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.07622Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.07622Inherited
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.07622Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1089Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.2346Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.4235Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0Direct
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.02847Inherited
    57184,57184,57581
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.02847Inherited
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.07622Inherited
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.07622Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.2598Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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