SUPERFAMILY 1.75 HMM library and genome assignments server

Phenotypic Abnormality (PA): Abnormality of the genitourinary system

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   Phenotypic abnormality [HP:0000118] <21>
0:   Abnormality of the genitourinary system [HP:0000119] <5>(28|33) (33|12|4)
- 1:   Urogenital fistula [HP:0100589] <5>(1|1) (1|0|0)
- 1:   Abnormality of the urinary system [HP:0000079] <4>(15|17) (16|6|2)
- 1:   Neoplasm of the genitourinary tract [HP:0007379] <4>(3|4) (4|1|2)
- 1:   Abnormality of the genital system [HP:0000078] <3>(14|17) (18|4|2)
- 1:   Cloacal abnormality [HP:0012620] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PRTase-like0Direct
Cytochrome b5-like heme/steroid binding domain0Direct
BRK domain-like0Direct
Arginase/deacetylase0Direct
Doublecortin (DC)0Direct
Sema domain0Direct
BRCT domain0Direct
Alkaline phosphatase-like0.0003246Direct
TPR-like0.002582Inherited
HMG-box0.006308Inherited
(Trans)glycosidases0.01954Inherited
GroEL equatorial domain-like0.04614Inherited
CalX-like0.04614Inherited
C-type lectin-like0.0721Inherited
Acyl-CoA dehydrogenase NM domain-like0.08469Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.08469Inherited
EGF/Laminin0.0894Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1173Inherited
Snake toxin-like0.1334Inherited
Glutathione synthetase ATP-binding domain-like0.1334Inherited
Clc chloride channel0.194Inherited
SET domain0.2064Inherited
GLA-domain0.4279Inherited
Nuclear receptor ligand-binding domain0.4435Inherited
Ribosomal protein S5 domain 2-like0.5363Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.5448Inherited
Trypsin-like serine proteases0.8164Inherited
Complement control module/SCR domain0.8516Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Sema domain0Direct
BRK domain-like0Direct
alpha-Amylases, C-terminal beta-sheet domain0Direct
Doublecortin (DC)0Direct
DNA gyrase/MutL, second domain0Direct
RecA protein-like (ATPase-domain)0Direct
DNA gyrase/MutL, N-terminal domain0Direct
Arylsulfatase0Direct
Crotonase-like0Direct
Cytochrome b50Direct
Tetratricopeptide repeat (TPR)0.0002158Direct
HMG-box0.004553Inherited
Tandem AAA-ATPase domain0.006277Inherited
Noncollagenous (NC1) domain of collagen IV0.01912Inherited
Extended AAA-ATPase domain0.03302Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.03302Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.03302Inherited
CalX-beta domain0.03746Inherited
BC N-terminal domain-like0.03746Inherited
BC ATP-binding domain-like0.03746Inherited
ARID domain0.07204Inherited
Laminin-type module0.08117Inherited
Histone lysine methyltransferases0.1012Inherited
VWC domain0.1012Inherited
Clc chloride channel0.1717Inherited
I set domains0.3018Inherited
Nuclear receptor0.3437Inherited
Classic zinc finger, C2H20.3538Inherited
GLA-domain0.4028Inherited
Nuclear receptor ligand-binding domain0.4242Inherited
G proteins0.8013Inherited
Eukaryotic proteases0.8422Inherited
Complement control module/SCR domain0.8464Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
BRCT domain0Direct
Cytochrome b5-like heme/steroid binding domain0Direct
Sema domain0Direct
PRTase-like0Direct
BRK domain-like0Direct
Doublecortin (DC)0Direct
Arginase/deacetylase0Direct
Alkaline phosphatase-like0.0001673Direct
TPR-like0.001558Inherited
HMG-box0.004093Inherited
ClpP/crotonase0.004093Inherited
RING/U-box0.01147Inherited
(Trans)glycosidases0.01389Inherited
CalX-like0.03543Inherited
GroEL equatorial domain-like0.03543Inherited
C-type lectin-like0.05747Inherited
Acyl-CoA dehydrogenase NM domain-like0.06801Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.06801Inherited
ARID-like0.06975Inherited
EGF/Laminin0.07212Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.09662Inherited
Snake toxin-like0.111Inherited
Glutathione synthetase ATP-binding domain-like0.111Inherited
WD40 repeat-like0.1225Inherited
Clc chloride channel0.1659Inherited
SET domain0.1779Inherited
Protein kinase-like (PK-like)0.1835Inherited
GLA-domain0.3929Inherited
Nuclear receptor ligand-binding domain0.4082Inherited
Ribosomal protein S5 domain 2-like0.501Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.5095Inherited
Trypsin-like serine proteases0.7866Inherited
Complement control module/SCR domain0.8237Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0Direct
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0Direct
    52096,52096
  • 52096 - ClpP/crotonase
  • 52096 - ClpP/crotonase
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.001903Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01384Inherited
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.06801Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.09662Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.111Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1547Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.638Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01988Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.05535Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.4349Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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