SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Trypanosoma cruzi strain CL Brener

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

642 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Sialidases Concanavalin A-like lectins/glucanases 3219
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 5318
Actin-like ATPase domain Actin-like ATPase domain 198
TPR-like TPR-like 1913
Pectin lyase-like Pectin lyase-like 187
P-loop containing nucleoside triphosphate hydrolases Translation proteins 1610
ARM repeat ARM repeat 1410
Sialidases Sialidases 147
RNA-binding domain, RBD RNA-binding domain, RBD 138
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1311
Ypt/Rab-GAP domain of gyp1p Ypt/Rab-GAP domain of gyp1p 132
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 128
WD40 repeat-like WD40 repeat-like 116
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 114
PH domain-like Protein kinase-like (PK-like) 104
PLP-dependent transferases PLP-dependent transferases 103
Nucleotidyltransferase PAP/OAS1 substrate-binding domain 105
HAD-like Calcium ATPase, transmembrane domain M 104
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 92
cAMP-binding domain-like cAMP-binding domain-like 97
Calcium ATPase, transduction domain A HAD-like 93
Cysteine proteinases Calpain large subunit, middle domain (domain III) 97
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 82
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 82
Smp-1-like Cysteine proteinases 82
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 87
EF-G C-terminal domain-like EF-G C-terminal domain-like 87
GroEL-intermediate domain like GroEL equatorial domain-like 83
P-loop containing nucleoside triphosphate hydrolases Nucleic acid-binding proteins 83
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 82
Thioredoxin-like GST C-terminal domain-like 75
GroEL apical domain-like GroEL equatorial domain-like 73
Metalloproteases ("zincins"), catalytic domain Metalloproteases ("zincins"), catalytic domain 73
Cullin homology domain "Winged helix" DNA-binding domain 74
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 72
EF-hand EF-hand 76
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 73
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 72
Translation proteins EF-G C-terminal domain-like 76
Chaperone J-domain HSP40/DnaJ peptide-binding domain 65
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 65
GroEL apical domain-like GroEL-intermediate domain like 62
WD40 repeat-like Quinoprotein alcohol dehydrogenase-like 66
Sec1/munc18-like (SM) proteins Sec1/munc18-like (SM) proteins 61
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 65
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 65
Protein kinase-like (PK-like) ARM repeat 66
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 61
MFS general substrate transporter MFS general substrate transporter 62
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 54
Cullin repeat-like Cullin homology domain 52
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 53
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 55
Translation proteins Ribosomal protein S5 domain 2-like 54
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 54
Ribonuclease H-like DNA/RNA polymerases 53
GroES-like NAD(P)-binding Rossmann-fold domains 52
Pectin lyase-like Formin homology 2 domain (FH2 domain) 52
Cullin repeat-like "Winged helix" DNA-binding domain 52
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 52
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 53
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 54
CRAL/TRIO N-terminal domain CRAL/TRIO domain 54
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 52
SNARE-like SNARE fusion complex 52
SNARE-like Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor 52
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 54
Concanavalin A-like lectins/glucanases Concanavalin A-like lectins/glucanases 54
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 53
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 51
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 53
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 43
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 43
Ubiquitin-like Zn-binding ribosomal proteins 44
Cyclin-like Cyclin-like 42
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 41
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 42
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 43
Metallo-dependent hydrolases Metallo-dependent hydrolases 42
Glutathione synthetase ATP-binding domain-like PreATP-grasp domain 44
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 42
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 42
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 44
TPR-like Chaperone J-domain 44
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 43
P-loop containing nucleoside triphosphate hydrolases Sec63 N-terminal domain-like 42
UBC-like RING/U-box 42
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 42
Retrovirus zinc finger-like domains Retrovirus zinc finger-like domains 43
Thioredoxin-like Thioredoxin-like 44
PH domain-like P-loop containing nucleoside triphosphate hydrolases 43
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 43
Nucleic acid-binding proteins Translation proteins SH3-like domain 42
Periplasmic binding protein-like I Nucleotide cyclase 43
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 42
Thiolase-like Thiolase-like 43
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 43
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 32
vWA-like beta-sandwich domain of Sec23/24 32
Helical domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 32
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 31
FAD/NAD(P)-binding domain Ferredoxin reductase-like, C-terminal NADP-linked domain 32
ARM repeat WD40 repeat-like 33
vWA-like C-terminal, gelsolin-like domain of Sec23/24 32
Ubiquitin-like UBA-like 32
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 32
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 33
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Creatinase/aminopeptidase "Winged helix" DNA-binding domain 33
Zn-finger domain of Sec23/24 Helical domain of Sec23/24 32
Cysteine proteinases Cysteine proteinases 33
Zn-finger domain of Sec23/24 beta-sandwich domain of Sec23/24 32
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 32
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 33
RING/U-box RING/U-box 33
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 32
BRCT domain BRCT domain 32
L domain-like RNI-like 33
Zn-finger domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 32
P-loop containing nucleoside triphosphate hydrolases Phosphoglycerate mutase-like 33
Ubiquitin-like Type III secretory system chaperone-like 32
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 33
TPR-like SET domain 32
beta-sandwich domain of Sec23/24 Helical domain of Sec23/24 32
HMG-box HMG-box 32
C2 domain (Calcium/lipid-binding domain, CaLB) C2 domain (Calcium/lipid-binding domain, CaLB) 33
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 32
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Ferredoxin reductase-like, C-terminal NADP-linked domain 32
ApbE-like FAD/NAD(P)-binding domain 32
Periplasmic binding protein-like I Periplasmic binding protein-like I 32
Galactose oxidase, central domain Kelch motif 33
vWA-like Helical domain of Sec23/24 32
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 32
FAD/NAD(P)-binding domain Riboflavin synthase domain-like 32
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 32
BEACH domain WD40 repeat-like 33
Protein kinase-like (PK-like) FYVE/PHD zinc finger 33
Zn-finger domain of Sec23/24 vWA-like 32
beta-sandwich domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 32
RNI-like Cysteine proteinases 33
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 31
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 33
CoA-dependent acyltransferases CoA-dependent acyltransferases 32
Calpain large subunit, middle domain (domain III) Calpain large subunit, middle domain (domain III) 33
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Riboflavin synthase domain-like 32
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 32
Ubiquitin-like Ubiquitin-like 33
(Phosphotyrosine protein) phosphatases II (Phosphotyrosine protein) phosphatases II 32
RNI-like RNI-like 33
F1F0 ATP synthase subunit C F1F0 ATP synthase subunit C 32
Single hybrid motif CoA-dependent acyltransferases 32
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 33
Ankyrin repeat Ankyrin repeat 33
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
Clc chloride channel CBS-domain pair 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 22
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 21
Metallo-dependent phosphatases EF-hand 22
P-loop containing nucleoside triphosphate hydrolases TGS-like 21
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 22
ARM repeat RING/U-box 22
GST C-terminal domain-like GST C-terminal domain-like 22
(Phosphotyrosine protein) phosphatases II C2 domain (Calcium/lipid-binding domain, CaLB) 21
Eukaryotic RPB5 N-terminal domain RPB5-like RNA polymerase subunit 22
RING/U-box EF-hand 22
GAF domain-like HD-domain/PDEase-like 22
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 22
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 21
UBA-like UBA-like 22
Tricorn protease domain 2 WD40 repeat-like 22
Radical SAM enzymes Acyl-CoA N-acyltransferases (Nat) 21
Protein kinase-like (PK-like) EF-hand 21
Concanavalin A-like lectins/glucanases Hect, E3 ligase catalytic domain 22
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 21
GMP synthetase C-terminal dimerisation domain GMP synthetase C-terminal dimerisation domain 22
Initiation factor IF2/eIF5b, domain 3 Translation proteins 22
Putative DNA-binding domain Putative DNA-binding domain 21
P-loop containing nucleoside triphosphate hydrolases Microbial and mitochondrial ADK, insert "zinc finger" domain 21
RCC1/BLIP-II RCC1/BLIP-II 22
Rad51 N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 21
PAP/OAS1 substrate-binding domain PAP/Archaeal CCA-adding enzyme, C-terminal domain 22
Glutathione synthetase ATP-binding domain-like SET domain 22
ApbE-like Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 21
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit P-loop containing nucleoside triphosphate hydrolases 21
Bet v1-like Bet v1-like 22
GINS helical bundle-like PriA/YqbF domain 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 22
WD40 repeat-like RING/U-box 22
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 22
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 22
Quinoprotein alcohol dehydrogenase-like Quinoprotein alcohol dehydrogenase-like 22
PYP-like sensor domain (PAS domain) Protein kinase-like (PK-like) 22
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit EF-hand 22
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 21
Flavoproteins Riboflavin synthase domain-like 22
ApbE-like Ferredoxin reductase-like, C-terminal NADP-linked domain 21
P-loop containing nucleoside triphosphate hydrolases DNA ligase/mRNA capping enzyme, catalytic domain 22
ClpP/crotonase ClpP/crotonase 22
Ankyrin repeat P-loop containing nucleoside triphosphate hydrolases 22
POZ domain Skp1 dimerisation domain-like 22
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 22
Nucleotidylyl transferase Ribosomal protein L25-like 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 21
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 22
RNI-like Calpain large subunit, middle domain (domain III) 22
Ribosomal protein L6 Ribosomal protein L6 21
Putative DNA-binding domain Class II aaRS and biotin synthetases 21
WW domain CCCH zinc finger 22
Ran binding protein zinc finger-like Ran binding protein zinc finger-like 22
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 Zinc beta-ribbon 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 21
Nucleic acid-binding proteins Nucleic acid-binding proteins 22
CBS-domain pair cAMP-binding domain-like 21
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 22
GAF domain-like GAF domain-like 22
Phospholipase D/nuclease Phospholipase D/nuclease 22
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 22
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 22
ApbE-like Riboflavin synthase domain-like 21
Class II aaRS and biotin synthetases Class II aaRS ABD-related 22
Nucleic acid-binding proteins Eukaryotic type KH-domain (KH-domain type I) 21
Protein kinase-like (PK-like) Protein kinase-like (PK-like) 22
FYVE/PHD zinc finger P-loop containing nucleoside triphosphate hydrolases 22
Protein kinase-like (PK-like) RNI-like 22
SET domain HIT/MYND zinc finger-like 22
Translational machinery components L30e-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 22
WW domain WW domain 21
Kelch motif Kelch motif 22
L domain-like L domain-like 22
Translation initiation factor 2 beta, aIF2beta, N-terminal domain Zinc-binding domain of translation initiation factor 2 beta 22
beta-beta-alpha zinc fingers beta-beta-alpha zinc fingers 22
CRAL/TRIO domain Supernatant protein factor (SPF), C-terminal domain 22
cAMP-binding domain-like PYP-like sensor domain (PAS domain) 22
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 21
Kelch motif Protein kinase-like (PK-like) 22
Mitochondrial carrier Mitochondrial carrier 22
XPC-binding domain UBA-like 22
Ankyrin repeat Phosphoglycerate mutase-like 22
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 22
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 21
Restriction endonuclease-like RuvA domain 2-like 22
UBC-like P-loop containing nucleoside triphosphate hydrolases 22
Nucleotide cyclase Protein kinase-like (PK-like) 21
DNA polymerase beta, N-terminal domain-like PsbU/PolX domain-like 22
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 22
C2 domain (Calcium/lipid-binding domain, CaLB) ARM repeat 22
(Trans)glycosidases Glycosyl hydrolase domain 22
Translation proteins ThrRS/AlaRS common domain 22
WD40 repeat-like Tricorn protease N-terminal domain 11
FYVE/PHD zinc finger F-box domain 11
UBA-like SMR domain-like 11
F-box domain P-loop containing nucleoside triphosphate hydrolases 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Carbamoyl phosphate synthetase, large subunit connection domain Adenine nucleotide alpha hydrolases-like 11
Phosphoglycerate kinase cAMP-binding domain-like 11
ENTH/VHS domain GAT-like domain 11
TPR-like P-loop containing nucleoside triphosphate hydrolases 11
TATA-box binding protein-like DNA-glycosylase 11
cAMP-binding domain-like CheY-like 11
Flavoproteins Radical SAM enzymes 11
Domain of poly(ADP-ribose) polymerase ADP-ribosylation 11
Concanavalin A-like lectins/glucanases P-domain of calnexin/calreticulin 11
Ubiquitin-like ARM repeat 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
TPR-like Metallo-dependent phosphatases 11
NAD kinase/diacylglycerol kinase-like NAD kinase/diacylglycerol kinase-like 11
RNI-like DPP6 N-terminal domain-like 11
PreATP-grasp domain Single hybrid motif 11
NSFL1 (p97 ATPase) cofactor p47, SEP domain Ubiquitin-like 11
Acetyl-CoA synthetase-like Actin-like ATPase domain 11
PUA domain-like eIF1-like 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
Ubiquitin-like C2 domain (Calcium/lipid-binding domain, CaLB) 11
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 11
Subtilisin-like Galactose-binding domain-like 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
Six-hairpin glycosidases HAD-like 11
ISP domain Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Ankyrin repeat Acyl-CoA N-acyltransferases (Nat) 11
RNI-like CCCH zinc finger 11
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
RING/U-box B-box zinc-binding domain 11
L domain-like Ubiquitin-like 11
Zn-dependent exopeptidases Zn-dependent exopeptidases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Ribonuclease H-like Retrovirus zinc finger-like domains 11
Outer arm dynein light chain 1 RNI-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
P-loop containing nucleoside triphosphate hydrolases Formin homology 2 domain (FH2 domain) 11
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
PreATP-grasp domain Adenine nucleotide alpha hydrolases-like 11
Bet v1-like C2 domain (Calcium/lipid-binding domain, CaLB) 11
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 11
Translation proteins Translation proteins 11
P-loop containing nucleoside triphosphate hydrolases ARM repeat 11
MIT domain P-loop containing nucleoside triphosphate hydrolases 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Tex N-terminal region-like Ribonuclease H-like 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
Zn-binding ribosomal proteins Zn-binding ribosomal proteins 11
Metallo-hydrolase/oxidoreductase Rhodanese/Cell cycle control phosphatase 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
PX domain BAR/IMD domain-like 11
Glutathione synthetase ATP-binding domain-like Adenine nucleotide alpha hydrolases-like 11
Growth factor receptor domain Pectin lyase-like 11
NTF2-like RNA-binding domain, RBD 11
Ubiquitin-like Acid proteases 11
SET domain SET domain 11
Second domain of FERM RNI-like 11
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 11
alpha/beta-Hydrolases P-loop containing nucleoside triphosphate hydrolases 11
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 11
PH domain-like Galactose oxidase, central domain 11
P-loop containing nucleoside triphosphate hydrolases Calpain large subunit, middle domain (domain III) 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Galactose mutarotase-like HAD-like 11
Cupredoxins Cupredoxins 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases WW domain 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Cysteine proteinases Glutathione synthetase ATP-binding domain-like 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
PIN domain-like Nucleic acid-binding proteins 11
YbaK/ProRS associated domain C-terminal domain of ProRS 11
ARM repeat Subdomain of clathrin and coatomer appendage domain 11
DNase I-like Acetyl-CoA synthetase-like 11
FYVE/PHD zinc finger HD-domain/PDEase-like 11
ARM repeat Clathrin adaptor appendage domain 11
Thioredoxin-like P-loop containing nucleoside triphosphate hydrolases 11
ISP domain Riboflavin synthase domain-like 11
Pseudouridine synthase PUA domain-like 11
CCCH zinc finger Chaperone J-domain 11
S-adenosyl-L-methionine-dependent methyltransferases FAD/NAD(P)-binding domain 11
EF-hand P-loop containing nucleoside triphosphate hydrolases 11
PRP4-like WD40 repeat-like 11
Chaperone J-domain Homeodomain-like 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
WW domain FYVE/PHD zinc finger 11
TGS-like Class II aaRS ABD-related 11
Cdc48 domain 2-like P-loop containing nucleoside triphosphate hydrolases 11
SMAD/FHA domain RING/U-box 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
DNA-glycosylase Nudix 11
Eukaryotic type KH-domain (KH-domain type I) SMR domain-like 11
TATA-box binding protein-like TATA-box binding protein-like 11
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 11
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 L30e-like 11
YjeF N-terminal domain-like Ribokinase-like 11
PUG domain-like (Trans)glycosidases 11
EF-hand WD40 repeat-like 11
Ribonuclease H-like RuvA domain 2-like 11
SAM/Pointed domain P-loop containing nucleoside triphosphate hydrolases 11
EF-hand C2 domain (Calcium/lipid-binding domain, CaLB) 11
Hsp33 domain HSP33 redox switch-like 11
RNA-binding domain, RBD PABC (PABP) domain 11
HSP20-like chaperones TPR-like 11
Class II aaRS and biotin synthetases Translation proteins 11
POZ domain RCC1/BLIP-II 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Tudor/PWWP/MBT Zinc beta-ribbon 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
AttH-like Terpenoid synthases 11
FYVE/PHD zinc finger FYVE/PHD zinc finger 11
Pre-PUA domain PUA domain-like 11
TGS-like Class II aaRS and biotin synthetases 11
HAD-like AF1104-like 11
UBC-like Ribosomal protein S5 domain 2-like 11
Insect cysteine-rich antifreeze protein Insect cysteine-rich antifreeze protein 11
Thioredoxin-like Ubiquitin-like 11
TRAF domain-like POZ domain 11
GST C-terminal domain-like eEF1-gamma domain 11
Acetyl-CoA synthetase-like Acetyl-CoA synthetase-like 11
MgtE membrane domain-like MgtE membrane domain-like 11
ENTH/VHS domain P-loop containing nucleoside triphosphate hydrolases 11
Aldolase EF-hand 11
"Winged helix" DNA-binding domain Protein kinase-like (PK-like) 11
PH domain-like WD40 repeat-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Ribonuclease H-like HRDC-like 11
YVTN repeat-like/Quinoprotein amine dehydrogenase DPP6 N-terminal domain-like 11
DNase I-like Actin-like ATPase domain 11
RNI-like WD40 repeat-like 11
Polo-box domain Polo-box domain 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
CheY-like Protein kinase-like (PK-like) 11
HAD-like HAD-like 11
FKBP-like FKBP-like 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Methyl-accepting chemotaxis protein (MCP) signaling domain Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Methylglyoxal synthase-like Adenine nucleotide alpha hydrolases-like 11
HMA, heavy metal-associated domain HAD-like 11
Cap-Gly domain CRAL/TRIO domain 11
P-loop containing nucleoside triphosphate hydrolases BAR/IMD domain-like 11
L9 N-domain-like Ribonuclease H-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
DAK1/DegV-like DhaL-like 11
alpha-ketoacid dehydrogenase kinase, N-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
ARM repeat Cysteine proteinases 11
Dom34/Pelota N-terminal domain-like Translational machinery components 11
PH domain-like SAM/Pointed domain 11
Tex N-terminal region-like RuvA domain 2-like 11
Nucleotidyltransferase PAP/Archaeal CCA-adding enzyme, C-terminal domain 11
Chaperone J-domain CSL zinc finger 11
ARM repeat Arginase/deacetylase 11
EF-hand Tropomyosin 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
WD40 repeat-like PDZ domain-like 11
cAMP-binding domain-like C2 domain (Calcium/lipid-binding domain, CaLB) 11
alpha/beta-Hydrolases UBC-like 11
WWE domain WD40 repeat-like 11
Galactose-binding domain-like Spermadhesin, CUB domain 11
EF-hand FAD-linked oxidoreductase 11
ATP-dependent DNA ligase DNA-binding domain Nucleic acid-binding proteins 11
EF-hand Inorganic pyrophosphatase 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
RNA-binding domain, RBD Retrovirus zinc finger-like domains 11
Subtilisin-like Spermadhesin, CUB domain 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
NAD(P)-binding Rossmann-fold domains P-loop containing nucleoside triphosphate hydrolases 11
Formin homology 2 domain (FH2 domain) DNA ligase/mRNA capping enzyme, catalytic domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Quinoprotein alcohol dehydrogenase-like ARM repeat 11
WD40 repeat-like Ypt/Rab-GAP domain of gyp1p 11
Sec63 N-terminal domain-like E set domains 11
Bromodomain Bromodomain 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
EF-hand Glycerol-3-phosphate (1)-acyltransferase 11
Carbamoyl phosphate synthetase, large subunit connection domain Argininosuccinate synthetase, C-terminal domain 11
SNARE-like SNARE-like 11
Saposin SGNH hydrolase 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Dom34/Pelota N-terminal domain-like L30e-like 11
Galactose oxidase, central domain POZ domain 11
Dihydrofolate reductase-like Thymidylate synthase/dCMP hydroxymethylase 11
TPR-like HCP-like 11
RuvA domain 2-like RuvA domain 2-like 11
PH domain-like Homeodomain-like 11
SMAD/FHA domain FKBP-like 11
HAD-like Protein kinase-like (PK-like) 11
CRAL/TRIO N-terminal domain Supernatant protein factor (SPF), C-terminal domain 11
Clathrin heavy-chain terminal domain ARM repeat 11
Galactose mutarotase-like Six-hairpin glycosidases 11
PreATP-grasp domain Rudiment single hybrid motif 11
Galactose-binding domain-like ARM repeat 11
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Translational machinery components 11
Concanavalin A-like lectins/glucanases Ankyrin repeat 11
PYP-like sensor domain (PAS domain) Phosphoglycerate kinase 11
HAD-like P-loop containing nucleoside triphosphate hydrolases 11
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 11
YbaK/ProRS associated domain Class II aaRS and biotin synthetases 11
Calponin-homology domain, CH-domain EB1 dimerisation domain-like 11
DNA clamp DNA clamp 11
t-snare proteins SNARE fusion complex 11
Nucleoporin domain WD40 repeat-like 11
POZ domain POZ domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Thioredoxin-like eEF1-gamma domain 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
POZ domain Kelch motif 11
Metallo-hydrolase/oxidoreductase Metallo-hydrolase/oxidoreductase 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
cAMP-binding domain-like Protein kinase-like (PK-like) 11
B-box zinc-binding domain TPR-like 11
YVTN repeat-like/Quinoprotein amine dehydrogenase WD40 repeat-like 11
WGR domain-like ADP-ribosylation 11
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 11
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Arginase/deacetylase Arginase/deacetylase 11
RuvA domain 2-like Nucleic acid-binding proteins 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Fibronectin type III Fibronectin type III 11
Eukaryotic type KH-domain (KH-domain type I) Eukaryotic type KH-domain (KH-domain type I) 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Ankyrin repeat RING/U-box 11
SMAD/FHA domain Protein kinase-like (PK-like) 11
RNI-like EF-hand 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Activator of Hsp90 ATPase, Aha1 Bet v1-like 11
Carbamoyl phosphate synthetase, large subunit connection domain PreATP-grasp domain 11
P-loop containing nucleoside triphosphate hydrolases Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 11
N-terminal, heterodimerisation domain of RBP7 (RpoE) Nucleic acid-binding proteins 11
Rudiment single hybrid motif Single hybrid motif 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
CCCH zinc finger Retrovirus zinc finger-like domains 11
Zinc beta-ribbon Zinc beta-ribbon 11
Galactose mutarotase-like Glycosyl hydrolase domain 11
vWA-like SPOC domain-like 11
ADC-like P-loop containing nucleoside triphosphate hydrolases 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Ubiquitin-like PDZ domain-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
PH domain-like BEACH domain 11
WGR domain-like Domain of poly(ADP-ribose) polymerase 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
SNARE fusion complex SNARE fusion complex 11
C2 domain (Calcium/lipid-binding domain, CaLB) Ankyrin repeat 11
Doublecortin (DC) Doublecortin (DC) 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
PAZ domain Trimeric LpxA-like enzymes 11
alpha/beta knot alpha/beta knot 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
DPP6 N-terminal domain-like alpha/beta-Hydrolases 11
FYVE/PHD zinc finger GroEL apical domain-like 11
C-type lectin-like C-type lectin-like 11
Elongation factor TFIIS domain 2 Zinc beta-ribbon 11
RNI-like Hemopexin-like domain 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Nucleoside diphosphate kinase, NDK Nucleoside diphosphate kinase, NDK 11
EF-hand PLC-like phosphodiesterases 11
PurM N-terminal domain-like PurM C-terminal domain-like 11
Class II aaRS and biotin synthetases C-terminal domain of ProRS 11
Cyclophilin-like RNA-binding domain, RBD 11
RmlC-like cupins Thioredoxin-like 11
PUG domain-like PUG domain-like 11
CinA-like Nucleotidylyl transferase 11
Ubiquitin-like Protein kinase-like (PK-like) 11
Type III secretory system chaperone-like PDZ domain-like 11
Actin depolymerizing proteins Actin depolymerizing proteins 11
PK beta-barrel domain-like PK C-terminal domain-like 11
TGS-like ThrRS/AlaRS common domain 11
Single hybrid motif beta-sandwich domain of Sec23/24 11
HMA, heavy metal-associated domain Metal cation-transporting ATPase, ATP-binding domain N 11
Guanido kinase N-terminal domain Glutamine synthetase/guanido kinase 11
AttH-like Lipocalins 11
RING/U-box R3H domain 11
F-box domain Protein kinase-like (PK-like) 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
CBS-domain pair CBS-domain pair 11
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 11
FYVE/PHD zinc finger PH domain-like 11
PH domain-like PH domain-like 11
Nucleotide cyclase Nucleotide cyclase 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Ankyrin repeat alpha/beta-Hydrolases 11
ATP-dependent DNA ligase DNA-binding domain DNA ligase/mRNA capping enzyme, catalytic domain 11
Ran binding protein zinc finger-like Hect, E3 ligase catalytic domain 11
E set domains AMPKBI-like 11
Nucleotidylyl transferase tRNA-binding arm 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain FYVE/PHD zinc finger 11
P-loop containing nucleoside triphosphate hydrolases RING/U-box 11
Cyclophilin-like TPR-like 11
RNI-like Adenine nucleotide alpha hydrolases-like 11
NAD-binding domain of HMG-CoA reductase Substrate-binding domain of HMG-CoA reductase 11
Cytochrome b5-like heme/steroid binding domain Cytochrome b5-like heme/steroid binding domain 11
PsbU/PolX domain-like Nucleotidyltransferase 11
PLP-binding barrel Alanine racemase C-terminal domain-like 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain PH domain-like 11
MIR domain EF-hand 11
Ran binding protein zinc finger-like Concanavalin A-like lectins/glucanases 11
AN1-like Zinc finger AN1-like Zinc finger 11
Ubiquitin-like XPC-binding domain 11
Subunits of heterodimeric actin filament capping protein Capz WW domain 11
PLC-like phosphodiesterases C2 domain (Calcium/lipid-binding domain, CaLB) 11
RING/U-box FYVE/PHD zinc finger 11
Chromo domain-like Acyl-CoA N-acyltransferases (Nat) 11
beta-sandwich domain of Sec23/24 CoA-dependent acyltransferases 11
Thioredoxin-like ERP29 C domain-like 11
PYP-like sensor domain (PAS domain) CheY-like 11
Ankyrin repeat TPR-like 11
"Winged helix" DNA-binding domain E set domains 11
Cysteine alpha-hairpin motif Cysteine alpha-hairpin motif 11
C2 domain (Calcium/lipid-binding domain, CaLB) Protein kinase-like (PK-like) 11
Glycerol-3-phosphate (1)-acyltransferase Glycerol-3-phosphate (1)-acyltransferase 11
L domain-like Outer arm dynein light chain 1 11
"Winged helix" DNA-binding domain Sec63 N-terminal domain-like 11
Homeodomain-like Homeodomain-like 11
FKBP-like TPR-like 11
Thioredoxin-like RING/U-box 11
PreATP-grasp domain Argininosuccinate synthetase, C-terminal domain 11
WD40 repeat-like TPR-like 11
Smp-1-like Smp-1-like 11
ARM repeat Formin homology 2 domain (FH2 domain) 11
FYVE/PHD zinc finger Acyl-CoA N-acyltransferases (Nat) 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
Ubiquitin-like Cysteine proteinases 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Activating enzymes of the ubiquitin-like proteins Activating enzymes of the ubiquitin-like proteins 11
RNI-like YVTN repeat-like/Quinoprotein amine dehydrogenase 11
Alpha-L RNA-binding motif Pseudouridine synthase 11
RNI-like cAMP-binding domain-like 11
ARM repeat Calpain large subunit, middle domain (domain III) 11
HCP-like HCP-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Class II aaRS ABD-related C-terminal domain of ProRS 11
Galactose mutarotase-like (Trans)glycosidases 11
Cap-Gly domain CRAL/TRIO N-terminal domain 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Glutathione synthetase ATP-binding domain-like Argininosuccinate synthetase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases C2 domain (Calcium/lipid-binding domain, CaLB) 11
Glucocorticoid receptor-like (DNA-binding domain) RING/U-box 11
Tudor/PWWP/MBT YaeB-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
P-loop containing nucleoside triphosphate hydrolases RNA-binding domain, RBD 11
Methylglyoxal synthase-like Argininosuccinate synthetase, C-terminal domain 11
Rhodanese/Cell cycle control phosphatase S-adenosyl-L-methionine-dependent methyltransferases 11
cAMP-binding domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Tudor/PWWP/MBT Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Plus3-like RING/U-box 11
3-carboxy-cis,cis-mucoante lactonizing enzyme Quinoprotein alcohol dehydrogenase-like 11
R3H domain P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases E set domains 11
P-loop containing nucleoside triphosphate hydrolases vWA-like 11
Protein kinase-like (PK-like) Polo-box domain 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
SET domain RuBisCo LSMT C-terminal, substrate-binding domain 11
Glycoside hydrolase/deacetylase Galactose mutarotase-like 11
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 11
HSP20-like chaperones HCP-like 11
DNA ligase/mRNA capping enzyme, catalytic domain S-adenosyl-L-methionine-dependent methyltransferases 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
L domain-like (Phosphotyrosine protein) phosphatases II 11
PreATP-grasp domain Methylglyoxal synthase-like 11
(Phosphotyrosine protein) phosphatases II FYVE/PHD zinc finger 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
PH domain-like "Winged helix" DNA-binding domain 11
Protein kinase-like (PK-like) Cap-Gly domain 11
ARM repeat Hect, E3 ligase catalytic domain 11
DNase I-like GTPase activation domain, GAP 11
P-loop containing nucleoside triphosphate hydrolases UBA-like 11
P-loop containing nucleoside triphosphate hydrolases SMAD/FHA domain 11
Clathrin adaptor appendage domain Subdomain of clathrin and coatomer appendage domain 11
Ribonuclease H-like ADP-ribosylation 11
SH3-domain SH3-domain 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
tRNA-binding arm Class II aaRS and biotin synthetases 11
Cysteine proteinases PreATP-grasp domain 11

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