SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Candidatus Moranella endobia PCIT

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

246 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Actin-like ATPase domain Actin-like ATPase domain 62
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 55
P-loop containing nucleoside triphosphate hydrolases Translation proteins 44
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 42
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Alpha-L RNA-binding motif Pseudouridine synthase 31
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 31
Translation proteins EF-G C-terminal domain-like 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 22
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 22
Nucleic acid-binding proteins RuvA domain 2-like 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
4Fe-4S ferredoxins ADC-like 11
Phospholipase D/nuclease Phospholipase D/nuclease 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
RNase III domain-like dsRNA-binding domain-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
CheY-like C-terminal effector domain of the bipartite response regulators 11
Chaperone J-domain HSP40/DnaJ peptide-binding domain 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 11
Formyltransferase FMT C-terminal domain-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Thiolase-like Thiolase-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Ribosomal protein L6 Ribosomal protein L6 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
GroEL equatorial domain-like GroEL equatorial domain-like 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
TK C-terminal domain-like alpha-helical ferredoxin 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
DNA primase core DNA primase DnaG, C-terminal domain 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Putative DNA-binding domain Translation proteins 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Flavoproteins Riboflavin synthase domain-like 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
HesB-like domain Fe-S cluster assembly (FSCA) domain-like 11
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 11
Nucleotidylyl transferase tRNA-binding arm 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
Single hybrid motif CoA-dependent acyltransferases 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
TGS-like ThrRS/AlaRS common domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Ribulose-phoshate binding barrel Ribulose-phoshate binding barrel 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Translation proteins PRC-barrel domain 11
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 11
PDZ domain-like PDZ domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Nucleic acid-binding proteins PheT/TilS domain 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
RuvA domain 2-like BRCT domain 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
PheT/TilS domain Putative DNA-binding domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Zinc beta-ribbon DNA primase core 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
PK beta-barrel domain-like PK C-terminal domain-like 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
GroEL equatorial domain-like GroEL apical domain-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Trypsin-like serine proteases PDZ domain-like 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
PTS system fructose IIA component-like PTS IIb component 11
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 11
TGS-like Class II aaRS and biotin synthetases 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
2Fe-2S ferredoxin-like ADC-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
PreATP-grasp domain PreATP-grasp domain 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases GAD domain-like 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
TGS-like Class II aaRS ABD-related 11
PIN domain-like DNA/RNA polymerases 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
Band 7/SPFH domain Band 7/SPFH domain 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
L30e-like alpha/beta knot 11
Zinc beta-ribbon Zinc beta-ribbon 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
FKBP-like FKBP-like 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III alpha-helical ferredoxin 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Class II aaRS and biotin synthetases Translation proteins 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Translation proteins ThrRS/AlaRS common domain 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
PIN domain-like Ribonuclease H-like 11
DNA clamp DNA clamp 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Nqo5-like HydB/Nqo4-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Triger factor/SurA peptide-binding domain-like FKBP-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Thiamin diphosphate-binding fold (THDP-binding) alpha-helical ferredoxin 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Pseudouridine synthase PUA domain-like 11
PreATP-grasp domain Rudiment single hybrid motif 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Nucleic acid-binding proteins GAD domain-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
Ribonuclease H-like DNA/RNA polymerases 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Translation proteins Translation proteins 11
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Nucleic acid-binding proteins BRCT domain 11

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