SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Ralstonia eutropha JMP134

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

791 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 1612
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 683
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 4824
"Winged helix" DNA-binding domain GAF domain-like 412
GroES-like NAD(P)-binding Rossmann-fold domains 382
CheY-like C-terminal effector domain of the bipartite response regulators 323
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 324
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 3115
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 295
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 292
Thiolase-like Thiolase-like 251
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 233
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 2312
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 229
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 224
Homeodomain-like Homeodomain-like 216
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 217
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 208
Thioredoxin-like GST C-terminal domain-like 203
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 206
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 1916
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 196
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 174
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 174
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1714
Homodimeric domain of signal transducing histidine kinase CheY-like 1613
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 162
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 166
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 166
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 166
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 166
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 157
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 1512
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 154
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 155
"Winged helix" DNA-binding domain Chorismate lyase-like 153
ISP domain Bet v1-like 152
Actin-like ATPase domain Actin-like ATPase domain 155
cAMP-binding domain-like "Winged helix" DNA-binding domain 143
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 144
PYP-like sensor domain (PAS domain) Nucleotide cyclase 138
Cytochrome c Cytochrome c 125
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 126
PreATP-grasp domain Rudiment single hybrid motif 125
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 125
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 125
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 129
"Winged helix" DNA-binding domain PLP-dependent transferases 112
Enolase N-terminal domain-like Enolase C-terminal domain-like 112
Class I glutamine amidotransferase-like Homeodomain-like 111
Nucleotide cyclase EAL domain-like 118
P-loop containing nucleoside triphosphate hydrolases Translation proteins 116
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 103
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 104
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 102
Succinyl-CoA synthetase domains Glutathione synthetase ATP-binding domain-like 102
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 101
PYP-like sensor domain (PAS domain) CheY-like 108
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 104
P-loop containing nucleoside triphosphate hydrolases TPR-like 105
Molybdenum cofactor-binding domain CO dehydrogenase molybdoprotein N-domain-like 94
Phospholipase D/nuclease Phospholipase D/nuclease 95
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 91
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 94
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 91
PreATP-grasp domain Single hybrid motif 84
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 84
PYP-like sensor domain (PAS domain) EAL domain-like 86
Rudiment single hybrid motif Single hybrid motif 84
Calcium ATPase, transduction domain A HAD-like 86
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 81
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 85
Glutathione synthetase ATP-binding domain-like Single hybrid motif 84
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 86
P-loop containing nucleoside triphosphate hydrolases CheY-like 83
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 88
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 84
HAD-like Calcium ATPase, transmembrane domain M 86
ClpP/crotonase ClpP/crotonase 73
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 72
CheY-like Homeodomain-like 72
P-loop containing nucleoside triphosphate hydrolases C-terminal effector domain of the bipartite response regulators 74
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 74
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 64
Triger factor/SurA peptide-binding domain-like FKBP-like 64
TPR-like TPR-like 65
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 64
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 63
Translation proteins EF-G C-terminal domain-like 63
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 61
CheY-like Histidine-containing phosphotransfer domain, HPT domain 66
Homeodomain-like SIS domain 62
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 61
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 63
P-loop containing nucleoside triphosphate hydrolases MOP-like 61
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Lysozyme-like beta-lactamase/transpeptidase-like 64
Nucleotide cyclase P-loop containing nucleoside triphosphate hydrolases 52
TPR-like C-terminal effector domain of the bipartite response regulators 53
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 52
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 53
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 52
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 52
HlyD-like secretion proteins HlyD-like secretion proteins 53
Alpha-L RNA-binding motif Pseudouridine synthase 53
Nucleotide cyclase TPR-like 52
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 55
EF-G C-terminal domain-like EF-G C-terminal domain-like 52
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 53
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 55
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 52
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 43
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 42
PurM N-terminal domain-like PurM C-terminal domain-like 42
Nqo1 middle domain-like Nqo1C-terminal domain-like 43
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 42
ADC-like 2Fe-2S ferredoxin-like 42
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 41
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 42
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
ParB/Sulfiredoxin KorB DNA-binding domain-like 42
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 42
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 43
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 43
Folate-binding domain Aminomethyltransferase beta-barrel domain 42
ADC-like 4Fe-4S ferredoxins 42
PYP-like sensor domain (PAS domain) Homeodomain-like 43
Regulatory protein AraC Homeodomain-like 43
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 43
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 41
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 43
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 41
Formate dehydrogenase/DMSO reductase, domains 1-3 2Fe-2S ferredoxin-like 42
Formate dehydrogenase/DMSO reductase, domains 1-3 4Fe-4S ferredoxins 42
GAF domain-like Homeodomain-like 43
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 42
CheY-like CheY-like 43
PLP-binding barrel Alanine racemase C-terminal domain-like 42
RmlC-like cupins Homeodomain-like 42
GroES-like GroES-like 41
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 42
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
PH0987 N-terminal domain-like Cyclophilin-like 33
Translation proteins Ribosomal protein S5 domain 2-like 31
CBS-domain pair FAD-binding/transporter-associated domain-like 31
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 33
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 32
Nucleotidyltransferase ACT-like 32
HMA, heavy metal-associated domain HAD-like 33
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 32
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 31
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 32
Nucleotidyltransferase HD-domain/PDEase-like 32
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 33
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 32
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 31
MetI-like MetI-like 31
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 32
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
E set domains (Trans)glycosidases 33
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 33
CheY-like Methylesterase CheB, C-terminal domain 32
Histidine-containing phosphotransfer domain, HPT domain CheW-like 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
CheW-like CheY-like 33
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 33
HD-domain/PDEase-like ACT-like 32
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 31
Nucleotide-diphospho-sugar transferases PilZ domain-like 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Single hybrid motif CoA-dependent acyltransferases 32
Phage tail proteins gp5 N-terminal domain-like 32
(Trans)glycosidases Glycosyl hydrolase domain 33
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
ACT-like ACT-like 33
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 33
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 31
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 32
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 32
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 33
Aldolase post-HMGL domain-like 33
TrkA C-terminal domain-like TrkA C-terminal domain-like 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 32
Trypsin-like serine proteases PDZ domain-like 32
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 31
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 32
Cupredoxins Cytochrome c 32
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 32
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 32
Aconitase iron-sulfur domain LeuD/IlvD-like 32
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 31
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 32
Nucleic acid-binding proteins RuvA domain 2-like 33
Pectin lyase-like Autotransporter 32
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 33
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 32
Phage tail proteins Phage tail proteins 32
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 32
PDZ domain-like PDZ domain-like 32
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 22
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 21
FAD/NAD(P)-binding domain HI0933 insert domain-like 21
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 21
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 21
NagB/RpiA/CoA transferase-like 4Fe-4S ferredoxins 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
GroEL-intermediate domain like GroEL apical domain-like 21
beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain 22
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 21
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 22
Nucleotidyltransferase TGS-like 21
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 22
Thioredoxin-like Nqo1C-terminal domain-like 22
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 22
S-adenosyl-L-methionine-dependent methyltransferases PYP-like sensor domain (PAS domain) 22
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 22
CheY-like Nucleotide cyclase 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 21
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, peptide-binding domain 22
Formyltransferase FMT C-terminal domain-like 21
Cyclophilin-like Cyclophilin-like 22
L30e-like alpha/beta knot 21
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 21
NAD(P)-binding Rossmann-fold domains ACT-like 22
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 21
PPK N-terminal domain-like Phospholipase D/nuclease 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 21
PHP14-like Phospholipase D/nuclease 22
E set domains Glycosyl hydrolase domain 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 22
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 21
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Chemotaxis receptor methyltransferase CheR, N-terminal domain PYP-like sensor domain (PAS domain) 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Thioredoxin-like Nqo1 FMN-binding domain-like 22
Methylesterase CheB, C-terminal domain Chemotaxis receptor methyltransferase CheR, N-terminal domain 22
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 22
Cytochrome c C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase 21
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 21
Ligand-binding domain in the NO signalling and Golgi transport P-loop containing nucleoside triphosphate hydrolases 22
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 22
Methylesterase CheB, C-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 22
Translation proteins ThrRS/AlaRS common domain 22
CoA-transferase family III (CaiB/BaiF) CoA-transferase family III (CaiB/BaiF) 21
Rudiment single hybrid motif ClpP/crotonase 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 21
Ligand-binding domain in the NO signalling and Golgi transport Homeodomain-like 22
MoeA N-terminal region -like MoeA C-terminal domain-like 21
2Fe-2S ferredoxin-like alpha-helical ferredoxin 21
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 21
Clc chloride channel CBS-domain pair 21
Methylesterase CheB, C-terminal domain PYP-like sensor domain (PAS domain) 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
GAF domain-like Nucleotide cyclase 22
Adhesin YadA, collagen-binding domain Adhesin YadA, collagen-binding domain 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Thioredoxin-like Nqo1 middle domain-like 22
ACT-like Formyltransferase 21
Ribonuclease H-like DNA/RNA polymerases 22
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, catalytic domain 22
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 22
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 22
PK beta-barrel domain-like PK C-terminal domain-like 21
PYP-like sensor domain (PAS domain) GAF domain-like 22
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
HD-domain/PDEase-like TGS-like 21
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 21
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 22
Galactose mutarotase-like E set domains 21
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
HAMP domain-like PYP-like sensor domain (PAS domain) 22
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 21
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
Flavoproteins Riboflavin synthase domain-like 22
MOP-like MOP-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
YrdC/RibB RibA-like 21
Metallo-hydrolase/oxidoreductase SCP-like 22
GroEL equatorial domain-like GroEL apical domain-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Quinoprotein alcohol dehydrogenase-like Cytochrome c 21
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 21
GAF domain-like EAL domain-like 22
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 21
FMN-binding split barrel UbiD C-terminal domain-like 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
Adhesin YadA, collagen-binding domain Pili subunits 22
Single hybrid motif ClpP/crotonase 21
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 21
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
lambda repressor-like DNA-binding domains RmlC-like cupins 21
GroEL equatorial domain-like GroEL-intermediate domain like 21
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Aspartate/glutamate racemase Aspartate/glutamate racemase 21
Heme-dependent peroxidases Heme-dependent peroxidases 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
Oxidoreductase molybdopterin-binding domain E set domains 21
TGS-like ACT-like 21
MFS general substrate transporter S-adenosyl-L-methionine-dependent methyltransferases 22
GAF domain-like Homodimeric domain of signal transducing histidine kinase 22
PreATP-grasp domain ClpP/crotonase 21
PapD-like Periplasmic chaperone C-domain 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
PPK N-terminal domain-like PHP14-like 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 21
Glutathione synthetase ATP-binding domain-like ClpP/crotonase 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
PH0987 N-terminal domain-like Single hybrid motif 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
DHS-like NAD/FAD-binding domain CBS-domain pair 11
Nucleotide-binding domain Nucleotide-binding domain 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
Ribonuclease H-like GIY-YIG endonuclease 11
PDZ domain-like ClpP/crotonase 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
FliG FliG 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
PrpR receptor domain-like PYP-like sensor domain (PAS domain) 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
Translation proteins PRC-barrel domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
ABC transporter transmembrane region CheY-like 11
Rudiment single hybrid motif Cyclophilin-like 11
Homodimeric domain of signal transducing histidine kinase Homodimeric domain of signal transducing histidine kinase 11
vWA-like TPR-like 11
Protease propeptides/inhibitors Subtilisin-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
ADC-like Riboflavin synthase domain-like 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
PreATP-grasp domain PH0987 N-terminal domain-like 11
PLP-dependent transferases PLP-dependent transferases 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain CheY-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
PurS-like FGAM synthase PurL, linker domain 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
PGBD-like L,D-transpeptidase catalytic domain-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
FAS1 domain FAS1 domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
PreATP-grasp domain PreATP-grasp domain 11
Nucleic acid-binding proteins PheT/TilS domain 11
YajQ-like YajQ-like 11
FMN-binding split barrel GAF domain-like 11
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
GAF domain-like CheY-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Aldolase 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Pili subunits Pili subunits 11
Glutathione synthetase ATP-binding domain-like Cyclophilin-like 11
Ribbon-helix-helix ALDH-like 11
HMA, heavy metal-associated domain FAD/NAD(P)-binding domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
FAD/NAD(P)-binding domain Metallo-hydrolase/oxidoreductase 11
Single hybrid motif FAD/NAD(P)-binding domain 11
TGS-like Class II aaRS and biotin synthetases 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Nucleotidylyl transferase tRNA-binding arm 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
Phage tail proteins Phage fibre proteins 11
Cytochrome P450 Ferredoxin reductase-like, C-terminal NADP-linked domain 11
HAMP domain-like GAF domain-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) DNA-glycosylase 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase PP2C-like 11
Molybdenum cofactor-binding domain Bet v1-like 11
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
P-loop containing nucleoside triphosphate hydrolases WD40 repeat-like 11
PIN domain-like DNA/RNA polymerases 11
CBS-domain pair Nucleotide cyclase 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
cAMP-binding domain-like P-loop containing nucleoside triphosphate hydrolases 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
YjeF N-terminal domain-like Ribokinase-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 11
FAD-linked oxidoreductase ALDH-like 11
RuvA domain 2-like JAB1/MPN domain 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Pili subunits GspK insert domain-like 11
PurS-like PurM N-terminal domain-like 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Bacterial muramidases Lysozyme-like 11
4Fe-4S ferredoxins Riboflavin synthase domain-like 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
RNase III domain-like dsRNA-binding domain-like 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Homeodomain-like DNA-glycosylase 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
P-loop containing nucleoside triphosphate hydrolases ARM repeat 11
beta-Roll beta-Roll 11
PurS-like PurM C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
WD40 repeat-like WD40 repeat-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
S-adenosyl-L-methionine-dependent methyltransferases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Riboflavin synthase domain-like 11
Chorismate mutase II ACT-like 11
CBS-domain pair EAL domain-like 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
Sigma2 domain of RNA polymerase sigma factors NTF2-like 11
Nudix Metallo-hydrolase/oxidoreductase 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
EAL domain-like HD-domain/PDEase-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Single hybrid motif Single hybrid motif 11
lambda repressor-like DNA-binding domains PYP-like sensor domain (PAS domain) 11
Putative DNA-binding domain Cobalamin (vitamin B12)-binding domain 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Methylesterase CheB, C-terminal domain Homodimeric domain of signal transducing histidine kinase 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
"Winged helix" DNA-binding domain MOP-like 11
Carbamate kinase-like PUA domain-like 11
Carbamate kinase-like ACT-like 11
Tex N-terminal region-like Ribonuclease H-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
UROD/MetE-like UROD/MetE-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
S-adenosyl-L-methionine-dependent methyltransferases TPR-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
4Fe-4S ferredoxins Respiratory nitrate reductase 1 gamma chain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
FMN-linked oxidoreductases Nucleotide-binding domain 11
FAD-linked reductases, C-terminal domain Metallo-hydrolase/oxidoreductase 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Methylesterase CheB, C-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Ribbon-helix-helix FAD-linked oxidoreductase 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Nucleic acid-binding proteins BRCT domain 11
ClpP/crotonase NfeD domain-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Periplasmic binding protein-like II MetI-like 11
Resolvase-like Homeodomain-like 11
FAD-linked reductases, C-terminal domain SCP-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Tex N-terminal region-like RuvA domain 2-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Putative DNA-binding domain Translation proteins 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
PheT/TilS domain Putative DNA-binding domain 11
Cytochrome P450 2Fe-2S ferredoxin-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
FKBP-like FKBP-like 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Cobalamin (vitamin B12)-binding domain P-loop containing nucleoside triphosphate hydrolases 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Acetyl-CoA synthetase-like Thioesterase/thiol ester dehydrase-isomerase 11
Galactose-binding domain-like (Trans)glycosidases 11
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Ferritin-like Calcium ATPase, transmembrane domain M 11
Trigger factor ribosome-binding domain FKBP-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Ribosomal protein L6 Ribosomal protein L6 11
Ferritin-like Calcium ATPase, transduction domain A 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Cytochrome P450 Riboflavin synthase domain-like 11
alpha/beta-Hydrolases S-adenosyl-L-methionine-dependent methyltransferases 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 11
P-loop containing nucleoside triphosphate hydrolases WGR domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 11
FAD/NAD(P)-binding domain Folate-binding domain 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Bet v1-like GST C-terminal domain-like 11
Dihydropteroate synthetase-like Methionine synthase domain 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
DNA topoisomerase I domain DNA breaking-rejoining enzymes 11
CheY-like HD-domain/PDEase-like 11
ABC transporter transmembrane region ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
TGS-like Class II aaRS ABD-related 11
Rudiment single hybrid motif PH0987 N-terminal domain-like 11
cAMP-binding domain-like ABC transporter transmembrane region 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Ribonuclease H-like RuvA domain 2-like 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
lambda repressor-like DNA-binding domains P-loop containing nucleoside triphosphate hydrolases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
ADC-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
E set domains Autotransporter 11
Cobalamin (vitamin B12)-binding domain Cobalamin (vitamin B12)-dependent enzymes 11
PurS-like Class I glutamine amidotransferase-like 11
MFS general substrate transporter MFS general substrate transporter 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
HprK N-terminal domain-like PEP carboxykinase-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Translation proteins Translation proteins 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Dimeric alpha+beta barrel Dimeric alpha+beta barrel 11
CBS-domain pair CBS-domain pair 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
PUA domain-like alpha/beta knot 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like post-HMGL domain-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
HMA, heavy metal-associated domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
(Trans)glycosidases (Trans)glycosidases 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Globin-like Riboflavin synthase domain-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Chorismate mutase II Periplasmic binding protein-like II 11
CO dehydrogenase molybdoprotein N-domain-like Bet v1-like 11
SMAD/FHA domain SMAD/FHA domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
CheY-binding domain of CheA ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
CO dehydrogenase molybdoprotein N-domain-like Cytochrome c 11
a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
gp5 N-terminal domain-like Phage fibre proteins 11
Rudiment single hybrid motif post-HMGL domain-like 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
CBS-domain pair PYP-like sensor domain (PAS domain) 11
DinB/YfiT-like putative metalloenzymes C-type lectin-like 11
Homeodomain-like TPR-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
S-adenosyl-L-methionine-dependent methyltransferases Homodimeric domain of signal transducing histidine kinase 11
Alkaline phosphatase-like Concanavalin A-like lectins/glucanases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
lambda repressor-like DNA-binding domains LexA/Signal peptidase 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
Nucleic acid-binding proteins GAD domain-like 11
4Fe-4S ferredoxins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
PrpR receptor domain-like P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Cupredoxins Cupredoxins 11
YgfB-like Sec-C motif 11
Zinc beta-ribbon DNA primase core 11
RuvA domain 2-like RuvA domain 2-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
CheC-like Surface presentation of antigens (SPOA) 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors NTF2-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
PIN domain-like Ribonuclease H-like 11
PreATP-grasp domain post-HMGL domain-like 11
P-loop containing nucleoside triphosphate hydrolases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
TrkA C-terminal domain-like FAD-binding/transporter-associated domain-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
CheY-binding domain of CheA CheW-like 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
KorB DNA-binding domain-like C-terminal domain of transcriptional repressors 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Homeodomain-like C-terminal effector domain of the bipartite response regulators 11
Class II aaRS and biotin synthetases Translation proteins 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 11
Homeodomain-like TATA-box binding protein-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Glutathione synthetase ATP-binding domain-like PH0987 N-terminal domain-like 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
Histidine-containing phosphotransfer domain, HPT domain CheY-binding domain of CheA 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Hsp33 domain HSP33 redox switch-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
"Winged helix" DNA-binding domain ClpP/crotonase 11
DNA clamp DNA clamp 11
alpha/beta-Hydrolases NTF2-like 11
Nucleotide-diphospho-sugar transferases UDP-Glycosyltransferase/glycogen phosphorylase 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Glycosyl hydrolase domain Protein kinase-like (PK-like) 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
cAMP-binding domain-like FAD/NAD(P)-binding domain 11
(Phosphotyrosine protein) phosphatases II FAD/NAD(P)-binding domain 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Nucleotide cyclase SMAD/FHA domain 11
DNA-glycosylase Nudix 11
Periplasmic binding protein-like II ACT-like 11
RuvA domain 2-like BRCT domain 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
CO dehydrogenase ISP C-domain like Bet v1-like 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
YefM-like RelE-like 11
PreATP-grasp domain Cyclophilin-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
FabD/lysophospholipase-like FabD/lysophospholipase-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases UDP-Glycosyltransferase/glycogen phosphorylase 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Aldolase Single hybrid motif 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Rudiment single hybrid motif Aldolase 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
HD-domain/PDEase-like GAF domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases CheY-like 11
TATA-box binding protein-like DNA-glycosylase 11
CarD-like TRCF domain-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Lysozyme-like LysM domain 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
PrpR receptor domain-like Homeodomain-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
Molybdenum cofactor-binding domain Cytochrome c 11
TGS-like ThrRS/AlaRS common domain 11
Ribbon-helix-helix N-terminal domain of bifunctional PutA protein 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Bet v1-like Thioredoxin-like 11
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
DNA primase core DNA primase DnaG, C-terminal domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Single hybrid motif alpha/beta-Hydrolases 11
S-adenosyl-L-methionine-dependent methyltransferases Nucleotide-diphospho-sugar transferases 11
ParB/Sulfiredoxin S-adenosyl-L-methionine-dependent methyltransferases 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Thioredoxin-like TPR-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) TATA-box binding protein-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
RuvA domain 2-like MCP/YpsA-like 11
Cyclophilin-like Single hybrid motif 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Phase 1 flagellin Phase 1 flagellin 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Cobalamin (vitamin B12)-dependent enzymes 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
cAMP-binding domain-like cAMP-binding domain-like 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Macro domain-like Zn-dependent exopeptidases 11
Actin-like ATPase domain HD-domain/PDEase-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
Pseudouridine synthase PUA domain-like 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
2Fe-2S ferredoxin-like Bet v1-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
CheY-binding domain of CheA Homodimeric domain of signal transducing histidine kinase 11
Metalloproteases ("zincins"), catalytic domain PDZ domain-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
post-HMGL domain-like Single hybrid motif 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain Homodimeric domain of signal transducing histidine kinase 11
Periplasmic binding protein-like II Lysozyme-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Ribonuclease H-like Nucleic acid-binding proteins 11
FAD/NAD(P)-binding domain SCP-like 11
Putative DNA-binding domain CheY-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
PreATP-grasp domain Aldolase 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
ParB/Sulfiredoxin C-terminal domain of transcriptional repressors 11
Ferritin-like HAD-like 11
Class I glutamine amidotransferase-like Glycoside hydrolase/deacetylase 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
alpha/beta-Hydrolases AhpD-like 11

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