SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Brucella pinnipedialis B2/94

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

562 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2510
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 211
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 203
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 178
P-loop containing nucleoside triphosphate hydrolases MOP-like 162
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 165
Actin-like ATPase domain Actin-like ATPase domain 146
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 141
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 145
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 146
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 112
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 112
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 113
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 101
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 105
CheY-like C-terminal effector domain of the bipartite response regulators 102
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 85
GroES-like NAD(P)-binding Rossmann-fold domains 82
Thiolase-like Thiolase-like 81
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 83
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 73
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 76
Thioredoxin-like GST C-terminal domain-like 71
"Winged helix" DNA-binding domain GAF domain-like 71
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 76
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 74
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 63
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 61
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 63
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
cAMP-binding domain-like "Winged helix" DNA-binding domain 61
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 63
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 63
P-loop containing nucleoside triphosphate hydrolases Translation proteins 65
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 63
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 63
PreATP-grasp domain Rudiment single hybrid motif 63
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 51
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 53
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 52
"Winged helix" DNA-binding domain Chorismate lyase-like 51
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 54
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 52
HlyD-like secretion proteins HlyD-like secretion proteins 43
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 43
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 44
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 43
Enolase N-terminal domain-like Enolase C-terminal domain-like 41
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 41
Calcium ATPase, transduction domain A HAD-like 43
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 42
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 42
HAD-like Calcium ATPase, transmembrane domain M 43
Single hybrid motif CoA-dependent acyltransferases 42
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 41
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
Triger factor/SurA peptide-binding domain-like FKBP-like 44
Nucleic acid-binding proteins Nucleic acid-binding proteins 44
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 44
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Lysozyme-like PGBD-like 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 33
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 31
NAD(P)-binding Rossmann-fold domains ACT-like 33
Trypsin-like serine proteases PDZ domain-like 33
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 32
HMA, heavy metal-associated domain HAD-like 32
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 32
Nucleotide cyclase EAL domain-like 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 31
PLP-binding barrel Alanine racemase C-terminal domain-like 31
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Folate-binding domain Aminomethyltransferase beta-barrel domain 33
Lysozyme-like beta-lactamase/transpeptidase-like 33
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 31
ACT-like ACT-like 33
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 32
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 33
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 32
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 31
PreATP-grasp domain Single hybrid motif 32
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 32
PDZ domain-like PDZ domain-like 33
CheY-like Homeodomain-like 31
Alpha-L RNA-binding motif Pseudouridine synthase 32
CBS-domain pair FAD-binding/transporter-associated domain-like 31
Translation proteins EF-G C-terminal domain-like 33
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 31
CheY-like P-loop containing nucleoside triphosphate hydrolases 31
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 31
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 32
Nucleic acid-binding proteins RuvA domain 2-like 33
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
Homeodomain-like Homeodomain-like 32
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
Glutathione synthetase ATP-binding domain-like Single hybrid motif 32
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 31
Homeodomain-like SIS domain 32
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Rudiment single hybrid motif Single hybrid motif 32
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Nucleotide-diphospho-sugar transferases RmlC-like cupins 21
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 21
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 22
Translation proteins ThrRS/AlaRS common domain 22
Nucleotidyltransferase ACT-like 22
Pectin lyase-like Autotransporter 22
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 21
PYP-like sensor domain (PAS domain) EAL domain-like 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
MFS general substrate transporter MFS general substrate transporter 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 21
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 21
Homodimeric domain of signal transducing histidine kinase CheY-like 22
GroES-like GroES-like 21
Cytochrome c Cytochrome c 21
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 22
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 22
ClpP/crotonase ClpP/crotonase 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
TrkA C-terminal domain-like TrkA C-terminal domain-like 22
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
Class I glutamine amidotransferase-like Homeodomain-like 22
Cupredoxins Cupredoxins 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
RmlC-like cupins Homeodomain-like 21
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 21
FAD/NAD(P)-binding domain Folate-binding domain 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 21
PYP-like sensor domain (PAS domain) Nucleotide cyclase 22
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 21
Nucleotide-binding domain Nucleotide-binding domain 21
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
L30e-like alpha/beta knot 21
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 22
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Succinyl-CoA synthetase domains Glutathione synthetase ATP-binding domain-like 22
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 21
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 22
Pectin lyase-like Pectin lyase-like 22
lambda repressor-like DNA-binding domains RmlC-like cupins 22
PYP-like sensor domain (PAS domain) CheY-like 22
alpha-helical ferredoxin Nucleotide-binding domain 21
Phospholipase D/nuclease Phospholipase D/nuclease 22
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
Ribosomal protein S5 domain 2-like EF-G C-terminal domain-like 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 21
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 22
beta-lactamase/transpeptidase-like Sporulation related repeat 22
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 22
MetI-like MetI-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 22
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 22
Homeodomain-like Ribonuclease H-like 21
PurM N-terminal domain-like PurM C-terminal domain-like 22
Aldolase post-HMGL domain-like 22
CBS-domain pair MgtE membrane domain-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 11
PDZ domain-like ClpP/crotonase 11
RNase III domain-like dsRNA-binding domain-like 11
GAF domain-like Nucleotide cyclase 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
FliG FliG 11
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
GAF domain-like Phosphohistidine domain 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
MetI-like P-loop containing nucleoside triphosphate hydrolases 11
TPR-like S-adenosyl-L-methionine-dependent methyltransferases 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
DNA-glycosylase Nudix 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
Glycoside hydrolase/deacetylase UraD-Like 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Hsp33 domain HSP33 redox switch-like 11
PreATP-grasp domain post-HMGL domain-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
Duplicated hybrid motif PLP-dependent transferases 11
Thioredoxin-like Six-hairpin glycosidases 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Nucleic acid-binding proteins GAD domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Actin-like ATPase domain HD-domain/PDEase-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
PspA lactotransferrin-binding region OmpA-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
YlxR-like L30e-like 11
RuvA domain 2-like JAB1/MPN domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 11
NAD(P)-binding Rossmann-fold domains MurD-like peptide ligases, peptide-binding domain 11
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 11
"Winged helix" DNA-binding domain PLP-dependent transferases 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Glutathione synthetase ATP-binding domain-like post-HMGL domain-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Nucleotidyltransferase TGS-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Dihydropteroate synthetase-like Methionine synthase domain 11
HCP-like PGBD-like 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
GAF domain-like Homeodomain-like 11
Aldolase Single hybrid motif 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Ribonuclease H-like DNA/RNA polymerases 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
Formyltransferase FMT C-terminal domain-like 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
Single hybrid motif alpha/beta-Hydrolases 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
PGBD-like L,D-transpeptidase catalytic domain-like 11
PreATP-grasp domain Aldolase 11
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 11
Single hybrid motif Thiamin diphosphate-binding fold (THDP-binding) 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
HD-domain/PDEase-like Nucleotidyltransferase 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
FMN-binding split barrel UbiD C-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains MurD-like peptide ligases, catalytic domain 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
PRC-barrel domain PRC-barrel domain 11
Bacterial muramidases Lysozyme-like 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Ribosomal protein L6 Ribosomal protein L6 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 11
FMN-linked oxidoreductases 4Fe-4S ferredoxins 11
Poly A polymerase C-terminal region-like ACT-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
RmlC-like cupins S-adenosyl-L-methionine-dependent methyltransferases 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Nucleotidylyl transferase tRNA-binding arm 11
lambda repressor-like DNA-binding domains PUA domain-like 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
YjeF N-terminal domain-like Ribokinase-like 11
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
DNA clamp DNA clamp 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
P-loop containing nucleoside triphosphate hydrolases Protein kinase-like (PK-like) 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
PLP-dependent transferases PLP-dependent transferases 11
Nucleic acid-binding proteins PheT/TilS domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
YebC-like PFL-like glycyl radical enzymes 11
ADC synthase Class I glutamine amidotransferase-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Cytochrome c Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
D-aminopeptidase, middle and C-terminal domains D-aminopeptidase, middle and C-terminal domains 11
PUA domain-like alpha/beta knot 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 11
Flavoproteins Riboflavin synthase domain-like 11
NagB/RpiA/CoA transferase-like DAK1/DegV-like 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Ribonuclease H-like HRDC-like 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
HD-domain/PDEase-like ACT-like 11
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
TGS-like ACT-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
FAD-linked reductases, C-terminal domain Folate-binding domain 11
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
SIS domain CBS-domain pair 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Carbamate kinase-like ACT-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
FAD-linked reductases, C-terminal domain Aminomethyltransferase beta-barrel domain 11
Isochorismatase-like hydrolases ACP-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
RuvA domain 2-like RuvA domain 2-like 11
PHP14-like Phospholipase D/nuclease 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Carbamate kinase-like PUA domain-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Clc chloride channel CBS-domain pair 11
Nucleotidyltransferase substrate binding subunit/domain Poly A polymerase C-terminal region-like 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Thioredoxin-like TPR-like 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
DNA methylase specificity domain DNA methylase specificity domain 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex alpha/beta-Hydrolases 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Nucleic acid-binding proteins BRCT domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
P-loop containing nucleoside triphosphate hydrolases Cytidine deaminase-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
GIY-YIG endonuclease RuvA domain 2-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Class II aaRS and biotin synthetases GAD domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Protein kinase-like (PK-like) PLP-dependent transferases 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
post-HMGL domain-like Single hybrid motif 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
MgtE N-terminal domain-like CBS-domain pair 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
alpha-helical ferredoxin ARM repeat 11
ISP domain Bet v1-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Serine metabolism enzymes domain ACT-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Class II aaRS and biotin synthetases Translation proteins 11
YrdC/RibB RibA-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Tex N-terminal region-like RuvA domain 2-like 11
Macro domain-like Zn-dependent exopeptidases 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors DAK1/DegV-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Ribbon-helix-helix ACT-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
FAD-linked oxidoreductase ALDH-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
PheT/TilS domain Putative DNA-binding domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
Rudiment single hybrid motif post-HMGL domain-like 11
lambda repressor-like DNA-binding domains S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Tex N-terminal region-like Ribonuclease H-like 11
TPR-like TPR-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
PIN domain-like Ribonuclease H-like 11
ACT-like Formyltransferase 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Protein kinase-like (PK-like) Duplicated hybrid motif 11
S-adenosyl-L-methionine-dependent methyltransferases L30e-like 11
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
CoA-dependent acyltransferases CoA-dependent acyltransferases 11
CbiG N-terminal domain-like Tetrapyrrole methylase 11
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 11
TGS-like ThrRS/AlaRS common domain 11
Rudiment single hybrid motif Aldolase 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
beta-lactamase/transpeptidase-like D-aminopeptidase, middle and C-terminal domains 11
PHP domain-like AF1531-like 11
CarD-like TRCF domain-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
CheY-like CheY-like 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
RuvA domain 2-like BRCT domain 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
TGS-like Class II aaRS and biotin synthetases 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
HRDC-like HRDC-like 11
CheY-like Nucleotide cyclase 11
GroEL-intermediate domain like GroEL apical domain-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
PreATP-grasp domain PreATP-grasp domain 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors NagB/RpiA/CoA transferase-like 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
dUTPase-like dUTPase-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Apolipoprotein A-I Apolipoprotein A-I 11
Tropomyosin PGBD-like 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Ribonuclease H-like RuvA domain 2-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
Translation proteins PRC-barrel domain 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
PIN domain-like DNA/RNA polymerases 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Zinc beta-ribbon DNA primase core 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
TerB-like Chaperone J-domain 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
PGBD-like PGBD-like 11
Tropomyosin HCP-like 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
PPK N-terminal domain-like PHP14-like 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
Nitrous oxide reductase, N-terminal domain Cupredoxins 11
HD-domain/PDEase-like TGS-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
TGS-like Class II aaRS ABD-related 11
Single hybrid motif TK C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Aldolase 11
Translation proteins Translation proteins 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Periplasmic binding protein-like II ACT-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11

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