SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Pseudomonas protegens Pf-5

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Graph of adjacent domain pairs.


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Domain combination pairs

861 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 1411
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 7234
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 3915
CheY-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 3225
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 313
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 314
CheY-like Homodimeric domain of signal transducing histidine kinase 2922
CheY-like C-terminal effector domain of the bipartite response regulators 281
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 282
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 271
Homeodomain-like Homeodomain-like 256
GroES-like NAD(P)-binding Rossmann-fold domains 243
Thiolase-like Thiolase-like 237
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 235
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 2215
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 2114
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 219
Thioredoxin-like GST C-terminal domain-like 192
Nucleotide cyclase EAL domain-like 1812
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 175
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 177
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 165
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 1613
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 161
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 163
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 162
ACP-like ACP-like 1514
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 146
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 144
Actin-like ATPase domain Actin-like ATPase domain 144
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 147
PYP-like sensor domain (PAS domain) Nucleotide cyclase 1412
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 144
PYP-like sensor domain (PAS domain) CheY-like 1310
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 1311
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 123
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 123
"Winged helix" DNA-binding domain PLP-dependent transferases 121
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 123
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 123
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 123
RmlC-like cupins Homeodomain-like 122
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 124
CheY-like Histidine-containing phosphotransfer domain, HPT domain 1210
P-loop containing nucleoside triphosphate hydrolases MOP-like 121
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 124
ACP-like CoA-dependent acyltransferases 1110
CoA-dependent acyltransferases CoA-dependent acyltransferases 1110
Cytochrome c Cytochrome c 115
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 119
Acetyl-CoA synthetase-like ACP-like 1110
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 103
PYP-like sensor domain (PAS domain) EAL domain-like 108
CheY-like P-loop containing nucleoside triphosphate hydrolases 102
Class I glutamine amidotransferase-like Homeodomain-like 102
CoA-dependent acyltransferases Acetyl-CoA synthetase-like 109
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 93
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 91
Regulatory protein AraC Homeodomain-like 93
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 93
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 92
"Winged helix" DNA-binding domain GAF domain-like 91
CheY-like Homeodomain-like 91
HAD-like Calcium ATPase, transmembrane domain M 85
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 83
ACP-like Thiolase-like 88
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 83
Calcium ATPase, transduction domain A HAD-like 85
PreATP-grasp domain Rudiment single hybrid motif 83
PYP-like sensor domain (PAS domain) Homeodomain-like 85
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 82
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 85
P-loop containing nucleoside triphosphate hydrolases Translation proteins 86
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 82
Thiolase-like NAD(P)-binding Rossmann-fold domains 77
ISP domain Bet v1-like 72
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 74
Phospholipase D/nuclease Phospholipase D/nuclease 74
NAD(P)-binding Rossmann-fold domains ACP-like 77
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 71
lambda repressor-like DNA-binding domains RmlC-like cupins 71
Acetyl-CoA synthetase-like Acetyl-CoA synthetase-like 76
Homeodomain-like SIS domain 61
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 63
Ribosomal protein S5 domain 2-like P-loop containing nucleoside triphosphate hydrolases 66
PLP-binding barrel Alanine racemase C-terminal domain-like 62
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 66
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 61
HlyD-like secretion proteins HlyD-like secretion proteins 62
ACT-like ACT-like 63
MetI-like MetI-like 62
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 51
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 52
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 55
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 54
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 51
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 53
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 54
"Winged helix" DNA-binding domain Chorismate lyase-like 51
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 55
Alpha-L RNA-binding motif Pseudouridine synthase 52
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 51
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 53
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 53
CheY-like EAL domain-like 53
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 52
CheW-like CheY-like 54
lambda repressor-like DNA-binding domains LexA/Signal peptidase 41
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
UDP-Glycosyltransferase/glycogen phosphorylase Nucleotide-diphospho-sugar transferases 42
Periplasmic binding protein-like II PYP-like sensor domain (PAS domain) 43
(Trans)glycosidases Glycosyl hydrolase domain 44
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 41
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 43
ACP-like S-adenosyl-L-methionine-dependent methyltransferases 44
CheY-like Nucleotide cyclase 44
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 42
P-loop containing nucleoside triphosphate hydrolases ACT-like 42
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 43
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 43
NAD(P)-binding Rossmann-fold domains S-adenosyl-L-methionine-dependent methyltransferases 44
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 43
CheY-like CheY-like 44
CBS-domain pair FAD-binding/transporter-associated domain-like 41
GAF domain-like Homodimeric domain of signal transducing histidine kinase 44
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 41
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 43
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 42
ACP-like alpha/beta-Hydrolases 44
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
cAMP-binding domain-like "Winged helix" DNA-binding domain 41
GAF domain-like PYP-like sensor domain (PAS domain) 44
P-loop containing nucleoside triphosphate hydrolases GAF domain-like 44
Class II aaRS and biotin synthetases Class II aaRS ABD-related 43
Folate-binding domain Aminomethyltransferase beta-barrel domain 42
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 43
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 43
Phage tail proteins Phage tail proteins 44
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
Nucleic acid-binding proteins RuvA domain 2-like 44
PurM N-terminal domain-like PurM C-terminal domain-like 42
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 42
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 32
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 32
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 32
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 31
Acetyl-CoA synthetase-like alpha/beta-Hydrolases 33
Periplasmic binding protein-like II Histidine-containing phosphotransfer domain, HPT domain 32
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 33
Nucleotidyltransferase ACT-like 32
HD-domain/PDEase-like ACT-like 32
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 31
HMA, heavy metal-associated domain HAD-like 32
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 32
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 32
ClpP/crotonase ClpP/crotonase 32
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 31
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Aldolase post-HMGL domain-like 32
PreATP-grasp domain Single hybrid motif 32
ARM repeat TPR-like 33
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 32
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 33
Formyltransferase FMT C-terminal domain-like 33
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 33
Glutathione synthetase ATP-binding domain-like Single hybrid motif 32
E set domains (Trans)glycosidases 33
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 33
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 31
PapD-like Periplasmic chaperone C-domain 31
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 31
HPr-like Phosphoenolpyruvate/pyruvate domain 32
LeuD/IlvD-like Aconitase iron-sulfur domain 33
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 31
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 32
Periplasmic binding protein-like II Periplasmic binding protein-like II 32
Triger factor/SurA peptide-binding domain-like FKBP-like 33
Single hybrid motif CoA-dependent acyltransferases 33
Thiolase-like S-adenosyl-L-methionine-dependent methyltransferases 33
Enolase N-terminal domain-like Enolase C-terminal domain-like 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Histidine-containing phosphotransfer domain, HPT domain CheW-like 33
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
HPr-like Phosphohistidine domain 32
Cupredoxins Cupredoxins 32
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 32
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 32
beta-Roll beta-Roll 32
Nucleotide-diphospho-sugar transferases RmlC-like cupins 31
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 32
GAF domain-like Nucleotide cyclase 33
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 33
CoA-dependent acyltransferases alpha/beta-Hydrolases 33
Translation proteins EF-G C-terminal domain-like 33
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
Phage tail proteins gp5 N-terminal domain-like 33
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 32
GAF domain-like Homeodomain-like 33
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 33
Periplasmic binding protein-like II CheY-like 32
gp5 N-terminal domain-like Phage fibre proteins 33
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 32
CheY-like HD-domain/PDEase-like 31
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 31
Rudiment single hybrid motif Single hybrid motif 32
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 31
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 32
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 31
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 31
Nucleotidyltransferase HD-domain/PDEase-like 32
PK beta-barrel domain-like PK C-terminal domain-like 21
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 21
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 22
TGS-like Class II aaRS and biotin synthetases 21
PUA domain-like Ribosomal protein S5 domain 2-like 22
TGS-like ThrRS/AlaRS common domain 21
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 21
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
HAMP domain-like CheY-like 22
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 22
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
P-loop containing nucleoside triphosphate hydrolases TPR-like 21
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 22
MOP-like MOP-like 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
ThrRS/AlaRS common domain Class II aaRS ABD-related 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 21
Ribosomal protein S5 domain 2-like EF-G C-terminal domain-like 22
Phage tail proteins Phage fibre proteins 22
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 21
Duplicated hybrid motif Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 21
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
Acetyl-CoA synthetase-like S-adenosyl-L-methionine-dependent methyltransferases 22
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Duplicated hybrid motif Phosphoenolpyruvate/pyruvate domain 21
Metalloproteases ("zincins"), catalytic domain beta-Roll 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 22
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 22
PH0987 N-terminal domain-like Cyclophilin-like 21
DsbC/DsbG N-terminal domain-like Thioredoxin-like 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
TPR-like C-terminal effector domain of the bipartite response regulators 21
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 21
HD-domain/PDEase-like TGS-like 21
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 21
Cytidine deaminase-like Dihydrofolate reductase-like 21
TGS-like Class II aaRS ABD-related 21
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
alpha/beta-Hydrolases beta-Roll 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 22
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 22
Duplicated hybrid motif HPr-like 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 21
Trypsin-like serine proteases PDZ domain-like 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 22
Duplicated hybrid motif Phosphohistidine domain 21
Lysozyme-like beta-lactamase/transpeptidase-like 22
E set domains Glycosyl hydrolase domain 22
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 22
vWA-like TPR-like 21
TGS-like ACT-like 21
alpha/beta-Hydrolases S-adenosyl-L-methionine-dependent methyltransferases 22
ACT-like Formyltransferase 21
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 22
Protein kinase-like (PK-like) PLP-dependent transferases 22
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 22
FAD/NAD(P)-binding domain HI0933 insert domain-like 21
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 21
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 22
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
Pectin lyase-like Autotransporter 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
PLP-dependent transferases PLP-dependent transferases 21
CheY-like Methylesterase CheB, C-terminal domain 21
Nucleotidyltransferase TGS-like 21
Galactose mutarotase-like E set domains 22
Thiolase-like FabD/lysophospholipase-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
alpha-D-mannose-specific plant lectins alpha-D-mannose-specific plant lectins 21
FabD/lysophospholipase-like ACP-like 22
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 21
2Fe-2S ferredoxin-like ADC-like 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
MoeA N-terminal region -like MoeA C-terminal domain-like 21
P-loop containing nucleoside triphosphate hydrolases C-terminal effector domain of the bipartite response regulators 21
Adenine nucleotide alpha hydrolases-like GAF domain-like 22
TPR-like TPR-like 22
Periplasmic binding protein-like II Lysozyme-like 22
PDZ domain-like PDZ domain-like 22
Ribonuclease H-like DNA/RNA polymerases 22
4Fe-4S ferredoxins ADC-like 21
HAMP domain-like PYP-like sensor domain (PAS domain) 21
Aspartate/glutamate racemase Aspartate/glutamate racemase 21
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 21
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 21
GAF domain-like EAL domain-like 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
alpha/beta-Hydrolases alpha/beta-Hydrolases 22
Subtilisin-like Autotransporter 21
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 22
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
PDZ domain-like ClpP/crotonase 21
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Nqo1 middle domain-like Nqo1C-terminal domain-like 22
E set domains E set domains 22
"Winged helix" DNA-binding domain LexA/Signal peptidase 21
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 21
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
alpha-helical ferredoxin Nucleotide-binding domain 22
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 22
RuvA domain 2-like RuvA domain 2-like 22
Translation proteins ThrRS/AlaRS common domain 22
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
"Winged helix" DNA-binding domain Metallo-dependent hydrolases 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
FMN-linked oxidoreductases 4Fe-4S ferredoxins 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
FMN-dependent nitroreductase-like Thiolase-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
CalX-like beta-Roll 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Ribonuclease H-like RuvA domain 2-like 11
Sensory domain-like PYP-like sensor domain (PAS domain) 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
(Trans)glycosidases Nucleotide-diphospho-sugar transferases 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
CBS-domain pair Nucleotide cyclase 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
Acetyl-CoA synthetase-like Thioesterase/thiol ester dehydrase-isomerase 11
PIN domain-like Ribonuclease H-like 11
Zn-dependent exopeptidases LysM domain 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
Nucleic acid-binding proteins PheT/TilS domain 11
Flavoproteins Riboflavin synthase domain-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
L domain-like Protein kinase-like (PK-like) 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Phoshotransferase/anion transport protein HPr-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
PurS-like PurM C-terminal domain-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Lysozyme-like LysM domain 11
Clavaminate synthase-like WD40 repeat-like 11
Zinc beta-ribbon Zinc beta-ribbon 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases MetI-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
TATA-box binding protein-like DNA-glycosylase 11
Pili subunits RuvA domain 2-like 11
GroEL-intermediate domain like GroEL apical domain-like 11
Phoshotransferase/anion transport protein Phosphohistidine domain 11
E set domains Cadherin-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
PHP14-like Phospholipase D/nuclease 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
FliG FliG 11
Sensory domain-like Histidine-containing phosphotransfer domain, HPT domain 11
HAMP domain-like Nucleotide cyclase 11
WD40 repeat-like Putative isomerase YbhE 11
Periplasmic binding protein-like II ACT-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Mechanosensitive channel protein MscS (YggB), C-terminal domain cAMP-binding domain-like 11
Trigger factor ribosome-binding domain FKBP-like 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Globin-like Riboflavin synthase domain-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Inosine monophosphate dehydrogenase (IMPDH) Nitrite and sulphite reductase 4Fe-4S domain-like 11
YrdC/RibB RibA-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
Ribokinase-like Nucleotidylyl transferase 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 11
FAD/NAD(P)-binding domain alpha/beta-Hydrolases 11
"Winged helix" DNA-binding domain MOP-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
EAL domain-like Sensory domain-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Heme-dependent catalase-like Class I glutamine amidotransferase-like 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
YajQ-like YajQ-like 11
PUA domain-like alpha/beta knot 11
Protein kinase-like (PK-like) vWA-like 11
RuvA domain 2-like JAB1/MPN domain 11
THUMP domain-like Adenine nucleotide alpha hydrolases-like 11
Pili subunits Pili subunits 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
Acyl-CoA N-acyltransferases (Nat) FKBP-like 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Chorismate mutase II ACT-like 11
Ribbon-helix-helix ALDH-like 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
THUMP domain-like Rhodanese/Cell cycle control phosphatase 11
Single hybrid motif Single hybrid motif 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
PheT/TilS domain Putative DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 11
UDP-Glycosyltransferase/glycogen phosphorylase Acyl-CoA N-acyltransferases (Nat) 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
PurS-like Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases Adenine nucleotide alpha hydrolases-like 11
HD-domain/PDEase-like HD-domain/PDEase-like 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Macro domain-like Zn-dependent exopeptidases 11
YWTD domain Nucleotide-diphospho-sugar transferases 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Phoshotransferase/anion transport protein Phosphoenolpyruvate/pyruvate domain 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Phoshotransferase/anion transport protein Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
alpha/beta-Hydrolases Glutathione synthetase ATP-binding domain-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
beta-Roll vWA-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Lysozyme-like PGBD-like 11
Glucose permease domain IIB Glucose permease domain IIB 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Bacterial muramidases Lysozyme-like 11
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 11
GIY-YIG endonuclease RuvA domain 2-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 11
FMN-binding split barrel Riboflavin synthase domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Hsp33 domain HSP33 redox switch-like 11
P-loop containing nucleoside triphosphate hydrolases Lysozyme-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
Ribosomal protein L6 Ribosomal protein L6 11
CheY-like TPR-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
(Trans)glycosidases Fibronectin type III 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
CheY-like CheC-like 11
FKBP-like FKBP-like 11
Periplasmic binding protein-like II OmpA-like 11
FAD-linked oxidoreductase ALDH-like 11
TSP type-3 repeat OmpA-like 11
Sensory domain-like CheY-like 11
Nucleotidylyl transferase YegP-like 11
Formyltransferase ClpP/crotonase 11
Single hybrid motif alpha/beta-Hydrolases 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
NAD(P)-binding Rossmann-fold domains alpha/beta-Hydrolases 11
Fibronectin type III Carbohydrate binding domain 11
PreATP-grasp domain ClpP/crotonase 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
GAF domain-like GAF domain-like 11
Cytochrome c E set domains 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Acyl-CoA N-acyltransferases (Nat) CoA-dependent acyltransferases 11
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
Carbamate kinase-like ACT-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
Ribbon-helix-helix FAD-linked oxidoreductase 11
GroES-like GroES-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
TROVE domain-like vWA-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
YbaK/ProRS associated domain HD-domain/PDEase-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
CheC-like Surface presentation of antigens (SPOA) 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Duplicated hybrid motif PLP-dependent transferases 11
Acetyl-CoA synthetase-like NAD(P)-binding Rossmann-fold domains 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Glutathione synthetase ATP-binding domain-like ClpP/crotonase 11
FMN-binding split barrel 2Fe-2S ferredoxin-like 11
Phage fibre proteins Phage fibre proteins 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
EPT/RTPC-like RNA 3'-terminal phosphate cyclase, RPTC, insert domain 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Pectin lyase-like Hedgehog/intein (Hint) domain 11
Nudix Nudix 11
ACT-like Homeodomain-like 11
Formyltransferase NAD(P)-binding Rossmann-fold domains 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
DNA methylase specificity domain DNA methylase specificity domain 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
P-loop containing nucleoside triphosphate hydrolases beta-lactamase/transpeptidase-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
PreATP-grasp domain PreATP-grasp domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
GAF domain-like HD-domain/PDEase-like 11
CoA-transferase family III (CaiB/BaiF) CoA-transferase family III (CaiB/BaiF) 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
cAMP-binding domain-like CBS-domain pair 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
RNase III domain-like dsRNA-binding domain-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
ALDH-like Thioesterase/thiol ester dehydrase-isomerase 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
Cupredoxins Cytochrome c 11
Galactose mutarotase-like Galactose mutarotase-like 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
CBS-domain pair MgtE membrane domain-like 11
LysM domain LysM domain 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
E set domains Autotransporter 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
Chorismate mutase II Periplasmic binding protein-like II 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Caspase-like 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Homeodomain-like Probable bacterial effector-binding domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
ACT-like PYP-like sensor domain (PAS domain) 11
6-phosphogluconate dehydrogenase C-terminal domain-like EPT/RTPC-like 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Ribbon-helix-helix N-terminal domain of bifunctional PutA protein 11
Zinc beta-ribbon DNA primase core 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 11
Thiolase-like alpha/beta-Hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Tropomyosin 11
HlyD-like secretion proteins Outer membrane efflux proteins (OEP) 11
FabD/lysophospholipase-like FabD/lysophospholipase-like 11
Acetyl-CoA synthetase-like Thiolase-like 11
Putative DNA-binding domain Translation proteins 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
PTS system IIB component-like PTS system IIB component-like 11
Galactose mutarotase-like Six-hairpin glycosidases 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Ribonuclease H-like Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
FMN-binding split barrel Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Acyl-CoA N-acyltransferases (Nat) Thiolase-like 11
Class II aaRS and biotin synthetases Translation proteins 11
post-HMGL domain-like Single hybrid motif 11
S-adenosyl-L-methionine-dependent methyltransferases FAD/NAD(P)-binding domain 11
Rudiment single hybrid motif ClpP/crotonase 11
NTF2-like Homeodomain-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
PGBD-like L,D-transpeptidase catalytic domain-like 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
FMN-dependent nitroreductase-like S-adenosyl-L-methionine-dependent methyltransferases 11
CoA-dependent acyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
FMN-dependent nitroreductase-like NAD(P)-binding Rossmann-fold domains 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 11
EPT/RTPC-like EPT/RTPC-like 11
Pili subunits GspK insert domain-like 11
(Trans)glycosidases Carbohydrate binding domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Nudix Thiamin phosphate synthase 11
HRDC-like HRDC-like 11
JAB1/MPN domain Cysteine proteinases 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
NAD(P)-binding Rossmann-fold domains EPT/RTPC-like 11
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 11
EAL domain-like CBS-domain pair 11
alpha/beta-Hydrolases Phosphohistidine domain 11
Tex N-terminal region-like RuvA domain 2-like 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
FAD/NAD(P)-binding domain Folate-binding domain 11
CbiG N-terminal domain-like Tetrapyrrole methylase 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Heme oxygenase-like Heme oxygenase-like 11
Barwin-like endoglucanases Sporulation related repeat 11
Nucleotidyltransferase Nucleotidyltransferase 11
DPP6 N-terminal domain-like alpha/beta-Hydrolases 11
FMT C-terminal domain-like ClpP/crotonase 11
PurS-like FGAM synthase PurL, linker domain 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
TerB-like Chaperone J-domain 11
"Winged helix" DNA-binding domain Rhodanese/Cell cycle control phosphatase 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
CarD-like TRCF domain-like 11
Phase 1 flagellin Phase 1 flagellin 11
GntR ligand-binding domain-like Metallo-dependent hydrolases 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
WD40 repeat-like WD40 repeat-like 11
DNA topoisomerase I domain DNA breaking-rejoining enzymes 11
Periplasmic binding protein-like II EAL domain-like 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
Acetyl-CoA synthetase-like FMN-dependent nitroreductase-like 11
Sensory domain-like Nucleotide cyclase 11
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Periplasmic binding protein-like II LigB-like 11
UROD/MetE-like UROD/MetE-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
(Trans)glycosidases Glycoside hydrolase/deacetylase 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
HD-domain/PDEase-like P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases GAD domain-like 11
Adenine nucleotide alpha hydrolases-like Rhodanese/Cell cycle control phosphatase 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Single hybrid motif ClpP/crotonase 11
Tex N-terminal region-like Ribonuclease H-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain TPR-like 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
FMN-linked oxidoreductases Nucleotide-binding domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
PPK N-terminal domain-like PHP14-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Translation proteins Translation proteins 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Galactose-binding domain-like Galactose-binding domain-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Translation proteins PRC-barrel domain 11
YegP-like YegP-like 11
Quinohemoprotein amine dehydrogenase A chain, domain 3 E set domains 11
DNA-glycosylase Nudix 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
"Winged helix" DNA-binding domain C-terminal domain of transcriptional repressors 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
L30e-like alpha/beta knot 11
RuvA domain 2-like BRCT domain 11
Periplasmic binding protein-like II Nucleotide cyclase 11
ADP-ribosylglycohydrolase Mss4-like 11
PHP domain-like AF1531-like 11
Periplasmic binding protein-like I Periplasmic binding protein-like I 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
FMT C-terminal domain-like NAD(P)-binding Rossmann-fold domains 11
Aldolase AFP III-like domain 11
OMPA-like OmpA-like 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
GspK insert domain-like RuvA domain 2-like 11
Thiolase-like CoA-dependent acyltransferases 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Cadherin-like Cadherin-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Carbamate kinase-like PUA domain-like 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
HD-domain/PDEase-like "Winged helix" DNA-binding domain 11
GAF domain-like CheY-like 11
Sm-like ribonucleoproteins cAMP-binding domain-like 11
PP2C-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
CalX-like vWA-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
Multiheme cytochromes TPR-like 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 11
P-loop containing nucleoside triphosphate hydrolases Homodimeric domain of signal transducing histidine kinase 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Ribonuclease H-like HRDC-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Nucleotide-binding domain Nucleotide-binding domain 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
Nucleic acid-binding proteins GAD domain-like 11
Acyl-CoA N-acyltransferases (Nat) ACP-like 11
Cytochrome c Quinohemoprotein amine dehydrogenase A chain, domain 3 11
Glycosyl hydrolase domain Protein kinase-like (PK-like) 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
NTF2-like Sec-C motif 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins BRCT domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
DNA clamp DNA clamp 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
HAMP domain-like EAL domain-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
Radical SAM enzymes RuvA domain 2-like 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Multiheme cytochromes ARM repeat 11
Protein kinase-like (PK-like) Duplicated hybrid motif 11
Pectin lyase-like Pectin lyase-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Phoshotransferase/anion transport protein Phoshotransferase/anion transport protein 11
Nqo5-like HydB/Nqo4-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
GAF domain-like Phosphohistidine domain 11
Tropomyosin Smc hinge domain 11
Thermostable phytase (3-phytase) Thermostable phytase (3-phytase) 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
CheY-like PP2C-like 11
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 11
ImpE-like TPR-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
MFS general substrate transporter S-adenosyl-L-methionine-dependent methyltransferases 11
Protein kinase-like (PK-like) Protein kinase-like (PK-like) 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
PIN domain-like DNA/RNA polymerases 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
Putative DNA-binding domain Probable bacterial effector-binding domain 11
Aldolase Single hybrid motif 11
Thioredoxin-like TPR-like 11
HesB-like domain Fe-S cluster assembly (FSCA) domain-like 11
DNA primase core DNA primase DnaG, C-terminal domain 11
Thioredoxin-like Thioredoxin-like 11
MgtE N-terminal domain-like CBS-domain pair 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
ACT-like HAD-like 11
TrkA C-terminal domain-like FAD-binding/transporter-associated domain-like 11
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 11
P-loop containing nucleoside triphosphate hydrolases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Pseudouridine synthase PUA domain-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
PurS-like PurM N-terminal domain-like 11
FMN-binding split barrel UbiD C-terminal domain-like 11
MOSC N-terminal domain-like PK beta-barrel domain-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Acyl-CoA N-acyltransferases (Nat) Glutathione synthetase ATP-binding domain-like 11
HCP-like HCP-like 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Cadherin-like Autotransporter 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
ACP-like FMN-dependent nitroreductase-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Quinoprotein alcohol dehydrogenase-like MetI-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Nucleotidylyl transferase tRNA-binding arm 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
S-adenosyl-L-methionine-dependent methyltransferases TPR-like 11
Methionine synthase domain Methionine synthase activation domain-like 11

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