SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Plasmodium yoelii ssp. yoelii 1

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).

Add or remove domain pairs

The links below permit the addition or removal of specific sets of domain combination pairs.


Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Add or remove genomes

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Add or remove genomes:
Include genomes:
Exclude genomes:


Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

601 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 5332
P-loop containing nucleoside triphosphate hydrolases Translation proteins 2012
RNA-binding domain, RBD RNA-binding domain, RBD 1813
Actin-like ATPase domain Actin-like ATPase domain 1710
GroEL equatorial domain-like GroEL apical domain-like 125
Calcium ATPase, transduction domain A HAD-like 118
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 118
HAD-like Calcium ATPase, transmembrane domain M 118
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 109
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 104
Nucleic acid-binding proteins Nucleic acid-binding proteins 98
GroEL equatorial domain-like GroEL-intermediate domain like 92
GroEL-intermediate domain like GroEL apical domain-like 92
Translation proteins EF-G C-terminal domain-like 86
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 86
ARM repeat ARM repeat 87
EF-G C-terminal domain-like EF-G C-terminal domain-like 86
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 74
WD40 repeat-like WD40 repeat-like 75
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 75
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 71
Ypt/Rab-GAP domain of gyp1p Ypt/Rab-GAP domain of gyp1p 74
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 71
Protein kinase-like (PK-like) EF-hand 63
TPR-like TPR-like 65
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 66
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 64
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 64
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 64
RNA-binding domain, RBD WW domain 55
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 54
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 55
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 53
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 52
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 54
Class II aaRS and biotin synthetases Class II aaRS ABD-related 54
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 54
Chaperone J-domain HSP40/DnaJ peptide-binding domain 54
Thioredoxin-like Thioredoxin-like 53
SNARE-like Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor 53
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 53
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 55
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 53
Translation proteins Ribosomal protein S5 domain 2-like 53
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 53
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 42
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 44
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 44
Translation proteins Initiation factor IF2/eIF5b, domain 3 44
Nucleotidyltransferase PAP/OAS1 substrate-binding domain 43
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 42
CCCH zinc finger CCCH zinc finger 41
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 44
Nucleotidylyl transferase ValRS/IleRS/LeuRS editing domain 43
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 43
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 42
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 44
ARM repeat Clathrin adaptor appendage domain 44
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 43
DNA/RNA polymerases Ribonuclease H-like 44
PP2C-like PP2C-like 33
Helical domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 33
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 33
Ricin B-like lectins Galactose-binding domain-like 32
Ubiquitin-like UBA-like 33
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 33
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 32
Cdc48 domain 2-like P-loop containing nucleoside triphosphate hydrolases 32
ADC-like P-loop containing nucleoside triphosphate hydrolases 32
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 32
vWA-like TSP-1 type 1 repeat 33
vWA-like Helical domain of Sec23/24 33
P-loop containing nucleoside triphosphate hydrolases TGS-like 32
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 32
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 33
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 32
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 33
Ribonuclease H-like Ribonuclease H-like 33
Galactose-binding domain-like Galactose-binding domain-like 33
Nucleotidylyl transferase Nucleotidylyl transferase 33
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 32
Kelch motif Kelch motif 33
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 32
beta-sandwich domain of Sec23/24 vWA-like 33
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 32
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 33
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 31
Eukaryotic type KH-domain (KH-domain type I) Eukaryotic type KH-domain (KH-domain type I) 33
beta-sandwich domain of Sec23/24 Zn-finger domain of Sec23/24 33
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 31
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 33
HCP-like HCP-like 33
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 33
SAM/Pointed domain Protein kinase-like (PK-like) 33
Nucleic acid-binding proteins Translation proteins SH3-like domain 32
vWA-like C-terminal, gelsolin-like domain of Sec23/24 33
beta-sandwich domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 33
beta-sandwich domain of Sec23/24 Helical domain of Sec23/24 33
EGF/Laminin EGF/Laminin 31
RING/U-box SMAD/FHA domain 32
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Protein kinase-like (PK-like) 33
cAMP-binding domain-like cAMP-binding domain-like 33
Single hybrid motif CoA-dependent acyltransferases 33
ADC-like Cdc48 domain 2-like 32
Growth factor receptor domain Growth factor receptor domain 22
Nucleotide cyclase Nucleotide cyclase 22
Kelch motif POZ domain 22
Galactose-binding domain-like Fibrinogen C-terminal domain-like 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
Sec63 N-terminal domain-like E set domains 22
TATA-box binding protein-like TATA-box binding protein-like 22
Phosphofructokinase Phosphofructokinase 22
P-loop containing nucleoside triphosphate hydrolases WD40 repeat-like 22
RCC1/BLIP-II RCC1/BLIP-II 22
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 22
Zn-finger domain of Sec23/24 Helical domain of Sec23/24 22
Alpha-L RNA-binding motif Pseudouridine synthase 21
Nucleic acid-binding proteins Eukaryotic type KH-domain (KH-domain type I) 22
Cullin homology domain "Winged helix" DNA-binding domain 21
Hect, E3 ligase catalytic domain Hect, E3 ligase catalytic domain 22
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 22
PK beta-barrel domain-like PK C-terminal domain-like 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Folate-binding domain Aminomethyltransferase beta-barrel domain 22
Galactose-binding domain-like LCCL domain 21
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 22
Zn-finger domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Ricin B-like lectins LCCL domain 21
Dipeptidyl peptidase I (cathepsin C), exclusion domain Cysteine proteinases 21
RING/U-box Cysteine proteinases 22
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 22
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain SAM/Pointed domain 22
DNase I-like DNase I-like 22
beta-beta-alpha zinc fingers beta-beta-alpha zinc fingers 22
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
Thiolase-like Thiolase-like 21
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 22
P-loop containing nucleoside triphosphate hydrolases Sec63 N-terminal domain-like 22
Enolase N-terminal domain-like Enolase C-terminal domain-like 21
EF-hand EF-hand 22
P-loop containing nucleoside triphosphate hydrolases FYVE/PHD zinc finger 22
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 21
Cyclin-like Cyclin-like 22
DNA clamp DNA clamp 21
E set domains E set domains 22
C2 domain (Calcium/lipid-binding domain, CaLB) C2 domain (Calcium/lipid-binding domain, CaLB) 22
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 22
Zn-finger domain of Sec23/24 vWA-like 22
Homeodomain-like Homeodomain-like 22
Macro domain-like Zn-dependent exopeptidases 22
beta and beta-prime subunits of DNA dependent RNA-polymerase beta and beta-prime subunits of DNA dependent RNA-polymerase 22
Cullin repeat-like "Winged helix" DNA-binding domain 21
Sec63 N-terminal domain-like Sec63 N-terminal domain-like 22
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 22
PheT/TilS domain Putative DNA-binding domain 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 22
PH domain-like Protein kinase-like (PK-like) 22
Fibrinogen C-terminal domain-like LCCL domain 21
Cap-Gly domain Ubiquitin-like 22
Ricin B-like lectins Fibrinogen C-terminal domain-like 21
E set domains P-loop containing nucleoside triphosphate hydrolases 22
Acid proteases DNA/RNA polymerases 22
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 22
ABC transporter transmembrane region ABC transporter transmembrane region 22
Translation initiation factor 2 beta, aIF2beta, N-terminal domain Zinc-binding domain of translation initiation factor 2 beta 22
PH domain-like EF-hand 22
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 22
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 22
Thioredoxin-like GST C-terminal domain-like 22
vWA-like vWA-like 22
Nucleotidylyl transferase Ribosomal protein L25-like 22
WW domain FF domain 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 22
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 22
N-terminal, heterodimerisation domain of RBP7 (RpoE) Nucleic acid-binding proteins 21
Rad51 N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 22
Pseudouridine synthase Pseudouridine synthase 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases DNA/RNA polymerases 22
GST C-terminal domain-like Nucleotidylyl transferase 22
ARM repeat Protein kinase-like (PK-like) 21
P-loop containing nucleoside triphosphate hydrolases RING/U-box 22
FYVE/PHD zinc finger FYVE/PHD zinc finger 22
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 22
Protein kinase-like (PK-like) Protein kinase-like (PK-like) 22
Restriction endonuclease-like RuvA domain 2-like 22
Ribosomal L27 protein-like Nucleic acid-binding proteins 22
Chaperone J-domain Thioredoxin-like 22
Cullin repeat-like Cullin homology domain 21
PRP4-like WD40 repeat-like 11
Nucleotide-diphospho-sugar transferases EF-hand 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Cap-Gly domain RNI-like 11
P-loop containing nucleoside triphosphate hydrolases Microbial and mitochondrial ADK, insert "zinc finger" domain 11
LCCL domain LCCL domain 11
LCCL domain SRCR-like 11
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 11
Oxysterol-binding protein-like Oxysterol-binding protein-like 11
TPR-like Formin homology 2 domain (FH2 domain) 11
FYSH domain Hypothetical protein AF0491, middle domain 11
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 11
Anthrax protective antigen LCCL domain 11
WD40 repeat-like Cyclophilin-like 11
ThrRS/AlaRS common domain Nucleotidylyl transferase 11
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase P-loop containing nucleoside triphosphate hydrolases 11
Kelch motif P-loop containing nucleoside triphosphate hydrolases 11
FumA C-terminal domain-like FumA C-terminal domain-like 11
SRCR-like S-adenosyl-L-methionine-dependent methyltransferases 11
SRCR-like SRCR-like 11
Single hybrid motif Single hybrid motif 11
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
Obg GTP-binding protein N-terminal domain Obg GTP-binding protein C-terminal domain 11
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) alpha-helical ferredoxin 11
PreATP-grasp domain Rudiment single hybrid motif 11
alpha/beta-Hydrolases alpha/beta-Hydrolases 11
ARM repeat "Winged helix" DNA-binding domain 11
Translational machinery components L30e-like 11
Folate-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Acid proteases Ribonuclease H-like 11
vWA-like Cysteine-rich domain 11
TSP-1 type 1 repeat TSP-1 type 1 repeat 11
P-loop containing nucleoside triphosphate hydrolases Tropomyosin 11
YbaK/ProRS associated domain C-terminal domain of ProRS 11
Calponin-homology domain, CH-domain EB1 dimerisation domain-like 11
Ankyrin repeat Hect, E3 ligase catalytic domain 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
Kelch motif ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Protein kinase-like (PK-like) Release factor 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
"Winged helix" DNA-binding domain HRDC-like 11
Ribosomal L27 protein-like Eukaryotic type KH-domain (KH-domain type I) 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
UBA-like PUG domain-like 11
DNA polymerase beta, N-terminal domain-like Restriction endonuclease-like 11
Activating enzymes of the ubiquitin-like proteins Rhodanese/Cell cycle control phosphatase 11
t-snare proteins SNARE fusion complex 11
Apolipoprotein A-I Apolipoprotein A-I 11
TATA-box binding protein-like DNA-glycosylase 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
WD40 repeat-like Quinoprotein alcohol dehydrogenase-like 11
TPR-like Metallo-dependent phosphatases 11
ADP-ribosylation B-box zinc-binding domain 11
Trimeric LpxA-like enzymes ARM repeat 11
Clathrin adaptor appendage domain Subdomain of clathrin and coatomer appendage domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Nucleotide-binding domain 11
Smc hinge domain Tropomyosin 11
Glycerol-3-phosphate (1)-acyltransferase Glycerol-3-phosphate (1)-acyltransferase 11
GST C-terminal domain-like Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
ATP-dependent DNA ligase DNA-binding domain Nucleic acid-binding proteins 11
PurM N-terminal domain-like PurM C-terminal domain-like 11
Alpha subunit of glutamate synthase, C-terminal domain alpha-helical ferredoxin 11
P-loop containing nucleoside triphosphate hydrolases Obg GTP-binding protein C-terminal domain 11
Pentapeptide repeat-like SET domain 11
Kelch motif Insect cysteine-rich antifreeze protein 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Rudiment single hybrid motif ClpP/crotonase 11
Cysteine proteinases UBC-like 11
LCCL domain S-adenosyl-L-methionine-dependent methyltransferases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases P-loop containing nucleoside triphosphate hydrolases 11
ISP transmembrane anchor ISP domain 11
Folate-binding domain TrmE connector domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Quinoprotein alcohol dehydrogenase-like Insect cysteine-rich antifreeze protein 11
P-loop containing nucleoside triphosphate hydrolases Concanavalin A-like lectins/glucanases 11
DNA primase core P-loop containing nucleoside triphosphate hydrolases 11
HIT/MYND zinc finger-like SET domain 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
RNA-binding domain, RBD PABC (PABP) domain 11
SWIB/MDM2 domain eIF1-like 11
Single hybrid motif ClpP/crotonase 11
SNARE-like Domain of the SRP/SRP receptor G-proteins 11
Dcp2 domain-like Nudix 11
Chaperone J-domain beta-beta-alpha zinc fingers 11
DNA primase core DNA/RNA polymerases 11
Flavoproteins Radical SAM enzymes 11
UBC-like Release factor 11
GroES-like NAD(P)-binding Rossmann-fold domains 11
Galactose oxidase, central domain S-adenosyl-L-methionine-dependent methyltransferases 11
Kringle-like TNF receptor-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
TPR-like RING/U-box 11
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 Elongation factor TFIIS domain 2 11
SNARE fusion complex SNARE fusion complex 11
CRAL/TRIO N-terminal domain CRAL/TRIO domain 11
Ribosomal protein L6 Ribosomal protein L6 11
Cytochrome c Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor 11
RNA-binding domain, RBD Surp module (SWAP domain) 11
TPR-like ARM repeat 11
Nucleotidyltransferase PAP/Archaeal CCA-adding enzyme, C-terminal domain 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Sec1/munc18-like (SM) proteins Sec1/munc18-like (SM) proteins 11
Protein kinase-like (PK-like) beta-lactamase/transpeptidase-like 11
Alpha subunit of glutamate synthase, C-terminal domain FAD/NAD(P)-binding domain 11
Nucleic acid-binding proteins eIF-2-alpha, C-terminal domain 11
UBC-like Protein kinase-like (PK-like) 11
Bet v1-like PH domain-like 11
Translation proteins ThrRS/AlaRS common domain 11
Ubiquitin-like XPC-binding domain 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Alpha subunit of glutamate synthase, C-terminal domain Nucleotide-binding domain 11
Metallo-hydrolase/oxidoreductase Metallo-hydrolase/oxidoreductase 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Chromo domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase P-loop containing nucleoside triphosphate hydrolases 11
Ubiquitin-like Zn-binding ribosomal proteins 11
Growth factor receptor domain TNF receptor-like 11
DHS-like NAD/FAD-binding domain Formate/glycerate dehydrogenase catalytic domain-like 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Mitochondrial carrier Mitochondrial carrier 11
Acetyl-CoA synthetase-like DHS-like NAD/FAD-binding domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
SET domain Ankyrin repeat 11
GST C-terminal domain-like eEF-1beta-like 11
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment DNA breaking-rejoining enzymes 11
Pseudouridine synthase PUA domain-like 11
HAD-like BRCT domain 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Pentapeptide repeat-like Nucleotidylyl transferase 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Ribosomal protein L22 Ribosomal protein L22 11
Lipase/lipooxygenase domain (PLAT/LH2 domain) S-adenosyl-L-methionine-dependent methyltransferases 11
CRAL/TRIO domain GTPase activation domain, GAP 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
GST C-terminal domain-like Nucleic acid-binding proteins 11
Acyl-CoA binding protein Ankyrin repeat 11
Phosphoglucomutase, C-terminal domain PRTase-like 11
Phosphoglucomutase, first 3 domains PRTase-like 11
DNA/RNA polymerases DNA/RNA polymerases 11
Chaperone J-domain Sec63 N-terminal domain-like 11
Class I glutamine amidotransferase-like PreATP-grasp domain 11
TPR-like Activator of Hsp90 ATPase, Aha1 11
Fe-only hydrogenase E set domains 11
ThrRS/AlaRS common domain ThrRS/AlaRS common domain 11
Surp module (SWAP domain) Surp module (SWAP domain) 11
PreATP-grasp domain ClpP/crotonase 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
ClpP/crotonase ClpP/crotonase 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Translation initiation factor 2 beta, aIF2beta, N-terminal domain ARM repeat 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Pectin lyase-like HD-domain/PDEase-like 11
Nucleic acid-binding proteins eIF2alpha middle domain-like 11
WW domain WW domain 11
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 11
SNARE-like SNARE fusion complex 11
Ubiquitin-like Ubiquitin-like 11
DNase I-like Aminoacid dehydrogenase-like, N-terminal domain 11
Macro domain-like CRAL/TRIO domain 11
NagB/RpiA/CoA transferase-like NAD(P)-binding Rossmann-fold domains 11
CBS-domain pair cAMP-binding domain-like 11
UBC-like UBA-like 11
Concanavalin A-like lectins/glucanases S-adenosyl-L-methionine-dependent methyltransferases 11
Creatinase/aminopeptidase Creatinase/aminopeptidase 11
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 11
Lipase/lipooxygenase domain (PLAT/LH2 domain) Concanavalin A-like lectins/glucanases 11
Bet v1-like Bet v1-like 11
Dihydrofolate reductase-like Thymidylate synthase/dCMP hydroxymethylase 11
Thioredoxin-like FAD-dependent thiol oxidase 11
alpha-helical ferredoxin FAD/NAD(P)-binding domain 11
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 Zinc beta-ribbon 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Carbamoyl phosphate synthetase, large subunit connection domain 11
DNA primase core Ribonuclease H-like 11
PYP-like sensor domain (PAS domain) GAF domain-like 11
PUA domain-like SWIB/MDM2 domain 11
DNase I-like NAD(P)-binding Rossmann-fold domains 11
HAD-like P-loop containing nucleoside triphosphate hydrolases 11
Flavoproteins Riboflavin synthase domain-like 11
HMG-box HMG-box 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
Kelch motif E set domains 11
4Fe-4S ferredoxins P-loop containing nucleoside triphosphate hydrolases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
PUA domain-like eIF1-like 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
LCCL domain Concanavalin A-like lectins/glucanases 11
Ankyrin repeat Ankyrin repeat 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
PH domain-like Oxysterol-binding protein-like 11
Chaperone J-domain CSL zinc finger 11
Cysteine proteinases Calpain large subunit, middle domain (domain III) 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Tricorn protease domain 2 WD40 repeat-like 11
Zinc-binding domain of translation initiation factor 2 beta ARM repeat 11
ISP domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
FMN-linked oxidoreductases alpha-helical ferredoxin 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
CCCH zinc finger RING/U-box 11
Chaperone J-domain Homeodomain-like 11
DHS-like NAD/FAD-binding domain NAD(P)-binding Rossmann-fold domains 11
EF-hand SAICAR synthase-like 11
Arginase/deacetylase SAICAR synthase-like 11
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 L30e-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Ribosomal protein L25-like Ribosomal protein L25-like 11
Chromo domain-like Chromo domain-like 11
Glutathione synthetase ATP-binding domain-like Phosphoglycerate mutase-like 11
Staphylococcal nuclease Tudor/PWWP/MBT 11
NAD(P)-binding Rossmann-fold domains P-loop containing nucleoside triphosphate hydrolases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
RING/U-box Homeodomain-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Metalloproteases ("zincins"), catalytic domain 4'-phosphopantetheinyl transferase 11
DPP6 N-terminal domain-like GYF domain 11
Cysteine proteinases UBA-like 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Activating enzymes of the ubiquitin-like proteins Activating enzymes of the ubiquitin-like proteins 11
Ubiquitin-like UBC-like 11
SNARE-like P-loop containing nucleoside triphosphate hydrolases 11
Putative DNA-binding domain Putative DNA-binding domain 11
ISP domain FAD/NAD(P)-binding domain 11
Insect cysteine-rich antifreeze protein Galactose oxidase, central domain 11
Lipase/lipooxygenase domain (PLAT/LH2 domain) LCCL domain 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
Nucleotide-diphospho-sugar transferases ARM repeat 11
Chromo domain-like Acyl-CoA N-acyltransferases (Nat) 11
Ribonuclease H-like DNA-binding domain of retroviral integrase 11
MIT domain P-loop containing nucleoside triphosphate hydrolases 11
RNI-like Ubiquitin-like 11
eIF2alpha middle domain-like eIF-2-alpha, C-terminal domain 11
PAP/OAS1 substrate-binding domain PAP/Archaeal CCA-adding enzyme, C-terminal domain 11
NSFL1 (p97 ATPase) cofactor p47, SEP domain Ubiquitin-like 11
ARM repeat GroEL apical domain-like 11
PX domain WD40 repeat-like 11
ARM repeat Sec7 domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
N-terminal Zn binding domain of HIV integrase DNA-binding domain of retroviral integrase 11
RNI-like RNI-like 11
Radical SAM enzymes Acyl-CoA N-acyltransferases (Nat) 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
TRAF domain-like Cysteine proteinases 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
EF-hand Metallo-dependent phosphatases 11
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FAD/NAD(P)-binding domain 11
PreATP-grasp domain Single hybrid motif 11
DUSP-like Cysteine proteinases 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Macro domain-like DNA polymerase III chi subunit 11
ATP-dependent DNA ligase DNA-binding domain DNA ligase/mRNA capping enzyme, catalytic domain 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Zinc beta-ribbon Zinc beta-ribbon 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
ARM repeat Subdomain of clathrin and coatomer appendage domain 11
Eukaryotic type KH-domain (KH-domain type I) Retrovirus zinc finger-like domains 11
Staphylococcal nuclease Staphylococcal nuclease 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Class I glutamine amidotransferase-like Glutathione synthetase ATP-binding domain-like 11
S-adenosylmethionine decarboxylase Alanine racemase C-terminal domain-like 11
Cysteine proteinases Cysteine proteinases 11
PH domain-like BEACH domain 11
GST C-terminal domain-like eEF1-gamma domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) N-terminal nucleophile aminohydrolases (Ntn hydrolases) 11
Elongation factor TFIIS domain 2 Zinc beta-ribbon 11
Rudiment single hybrid motif Single hybrid motif 11
Cdc48 domain 2-like RING/U-box 11
Chaperone J-domain E set domains 11
FYVE/PHD zinc finger Bromodomain 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Class II aaRS ABD-related C-terminal domain of ProRS 11
Eukaryotic RPB5 N-terminal domain RPB5-like RNA polymerase subunit 11
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 11
Ubiquitin-like Cysteine proteinases 11
WD40 repeat-like DPP6 N-terminal domain-like 11
Pentapeptide repeat-like Translation proteins 11
RING/U-box WD40 repeat-like 11
PH domain-like WD40 repeat-like 11
Cell-division protein ZipA, C-terminal domain DNA ligase/mRNA capping enzyme, catalytic domain 11
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 11
FMN-linked oxidoreductases Nucleotide-binding domain 11
GroEL equatorial domain-like GroEL equatorial domain-like 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
alpha/beta knot Nucleic acid-binding proteins 11
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 11
DNA mismatch repair protein MutL DNA mismatch repair protein MutL 11
Acetyl-CoA synthetase-like Thiamin diphosphate-binding fold (THDP-binding) 11
Protein prenylyltransferase L domain-like 11
Class I glutamine amidotransferase-like ADC synthase 11
YbaK/ProRS associated domain Class II aaRS and biotin synthetases 11
Kelch motif S-adenosyl-L-methionine-dependent methyltransferases 11
Trypsin-like serine proteases PDZ domain-like 11
CCCH zinc finger RNA-binding domain, RBD 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Zn-dependent exopeptidases DNA polymerase III chi subunit 11
Thioredoxin-like Ubiquitin-like 11
MCP/YpsA-like P-loop containing nucleoside triphosphate hydrolases 11
Protein prenylyltransferase Rps17e-like 11
S-adenosylmethionine decarboxylase PLP-binding barrel 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
FF domain FF domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Translational machinery components 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
Glutathione synthetase ATP-binding domain-like ClpP/crotonase 11
Acyl-CoA N-acyltransferases (Nat) Bromodomain 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
PLP-binding barrel Alanine racemase C-terminal domain-like 11
Lipase/lipooxygenase domain (PLAT/LH2 domain) SRCR-like 11
UBA-like UBA-like 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
SRCR-like Concanavalin A-like lectins/glucanases 11
Formate/glycerate dehydrogenase catalytic domain-like Formate/glycerate dehydrogenase catalytic domain-like 11
SMAD/FHA domain RNA-binding domain, RBD 11
Aldolase LuxS/MPP-like metallohydrolase 11
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 11
Creatinase/aminopeptidase "Winged helix" DNA-binding domain 11
SMAD/FHA domain SMAD/FHA domain 11
Nucleic acid-binding proteins Translation proteins 11
BRCT domain post-AAA+ oligomerization domain-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain PreATP-grasp domain 11
Calcium ATPase, transmembrane domain M Calcium ATPase, transmembrane domain M 11
Thioredoxin-like eEF1-gamma domain 11
PRTase-like PRTase-like 11
YWTD domain Growth factor receptor domain 11
Calpain large subunit, middle domain (domain III) Calpain large subunit, middle domain (domain III) 11
NagB/RpiA/CoA transferase-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
"Winged helix" DNA-binding domain Protein kinase-like (PK-like) 11
P-loop containing nucleoside triphosphate hydrolases Rad50 coiled-coil Zn hook 11
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 11
Class I glutamine amidotransferase-like Class I glutamine amidotransferase-like 11
Class II aaRS and biotin synthetases C-terminal domain of ProRS 11
FKBP-like TPR-like 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 11
P-loop containing nucleoside triphosphate hydrolases Ribonuclease H-like 11
Phospholipase D/nuclease Phospholipase D/nuclease 11
Class II aaRS and biotin synthetases SufE/NifU 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase GAF domain-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Anthrax protective antigen Galactose-binding domain-like 11
Translation proteins Translation proteins 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
PUA domain-like SET domain 11
Ribosomal protein L16p/L10e Ribosomal protein L14 11
Kringle-like Growth factor receptor domain 11
cAMP-binding domain-like Protein kinase-like (PK-like) 11
POZ domain Skp1 dimerisation domain-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Clathrin heavy-chain terminal domain ARM repeat 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
GST C-terminal domain-like Ribosomal protein L25-like 11
SET domain FYVE/PHD zinc finger 11
RING/U-box RING/U-box 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
N-terminal Zn binding domain of HIV integrase Ribonuclease H-like 11
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 11
ARM repeat GroEL equatorial domain-like 11
BRCT domain P-loop containing nucleoside triphosphate hydrolases 11
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
BEACH domain WD40 repeat-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Glutathione synthetase ATP-binding domain-like 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK Dihydropteroate synthetase-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Zinc beta-ribbon Cyclin-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Nucleic acid-binding proteins Initiation factor IF2/eIF5b, domain 3 11
Ubiquitin-like Acid proteases 11
RING/U-box RNA-binding domain, RBD 11
Galactose oxidase, central domain Metallo-dependent phosphatases 11
TPR-like PDZ domain-like 11
Class I glutamine amidotransferase-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
UBA-like XPC-binding domain 11
Pentapeptide repeat-like FYVE/PHD zinc finger 11
Insect cysteine-rich antifreeze protein S-adenosyl-L-methionine-dependent methyltransferases 11
L30e-like alpha/beta knot 11
Oligoxyloglucan reducing end-specific cellobiohydrolase Oligoxyloglucan reducing end-specific cellobiohydrolase 11
RNA-binding domain, RBD Tricorn protease domain 2 11
P-loop containing nucleoside triphosphate hydrolases EF-hand 11
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
tRNA-binding arm Class II aaRS and biotin synthetases 11
Kelch motif Galactose oxidase, central domain 11
Glycerol-3-phosphate (1)-acyltransferase Acetyl-CoA synthetase-like 11
RING/U-box UBA-like 11
"Winged helix" DNA-binding domain Sec63 N-terminal domain-like 11

Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes · Domain combination pairs ]