SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Gluconobacter oxydans 621H

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

519 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2414
Homeodomain-like Ribonuclease H-like 231
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 181
Actin-like ATPase domain Actin-like ATPase domain 126
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 127
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 106
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 102
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 94
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 93
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 84
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 85
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 85
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 85
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 85
CheY-like C-terminal effector domain of the bipartite response regulators 71
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 74
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 74
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 62
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 62
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 63
Cytochrome c Cytochrome c 64
GroES-like NAD(P)-binding Rossmann-fold domains 62
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
P-loop containing nucleoside triphosphate hydrolases Translation proteins 66
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 54
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 54
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 55
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 52
UDP-Glycosyltransferase/glycogen phosphorylase Nucleotide-diphospho-sugar transferases 52
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 41
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 41
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 43
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 41
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
PreATP-grasp domain Rudiment single hybrid motif 41
Triger factor/SurA peptide-binding domain-like FKBP-like 43
Thioredoxin-like GST C-terminal domain-like 41
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 43
Nucleotide cyclase EAL domain-like 43
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 41
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 41
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 44
ISP domain Bet v1-like 41
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 33
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 33
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 31
Trypsin-like serine proteases PDZ domain-like 32
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
PurM N-terminal domain-like PurM C-terminal domain-like 32
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 31
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 32
Alpha-L RNA-binding motif Pseudouridine synthase 31
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 32
CheY-like Homodimeric domain of signal transducing histidine kinase 33
GAF domain-like PYP-like sensor domain (PAS domain) 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
ACT-like ACT-like 33
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 32
HlyD-like secretion proteins HlyD-like secretion proteins 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 33
Resolvase-like Homeodomain-like 31
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 32
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 31
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 33
Translation proteins EF-G C-terminal domain-like 33
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 32
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 32
PLP-binding barrel Alanine racemase C-terminal domain-like 31
CheY-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 33
PYP-like sensor domain (PAS domain) Nucleotide cyclase 33
PDZ domain-like ClpP/crotonase 32
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
Acid proteases Acid proteases 21
DPP6 N-terminal domain-like alpha/beta-Hydrolases 22
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 22
CBS-domain pair FAD-binding/transporter-associated domain-like 21
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 22
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 21
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 22
P-loop containing nucleoside triphosphate hydrolases MOP-like 21
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 22
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
Phospholipase D/nuclease Phospholipase D/nuclease 22
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
TPR-like TPR-like 22
Single hybrid motif CoA-dependent acyltransferases 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 21
FAD/NAD(P)-binding domain HI0933 insert domain-like 21
ParB/Sulfiredoxin KorB DNA-binding domain-like 21
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 22
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 22
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 21
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
PYP-like sensor domain (PAS domain) EAL domain-like 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
Nucleic acid-binding proteins RuvA domain 2-like 22
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 21
HD-domain/PDEase-like Nucleotidyltransferase 22
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 22
CheY-like PYP-like sensor domain (PAS domain) 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
GAF domain-like GAF domain-like 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
OMPA-like OmpA-like 22
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 22
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 21
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 22
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 21
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 22
PDZ domain-like PDZ domain-like 21
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Formyltransferase FMT C-terminal domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
HRDC-like HRDC-like 11
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Nucleotide-diphospho-sugar transferases MoaD/ThiS 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
Quinoprotein alcohol dehydrogenase-like Cytochrome c 11
"Winged helix" DNA-binding domain Chorismate lyase-like 11
RNase III domain-like dsRNA-binding domain-like 11
GAF domain-like CheY-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
PLP-dependent transferases PLP-dependent transferases 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
Ribosomal protein L6 Ribosomal protein L6 11
Single hybrid motif TK C-terminal domain-like 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 11
DNA clamp DNA clamp 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Sensory domain-like GAF domain-like 11
Sensory domain-like Nucleotide cyclase 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Calcium ATPase, transmembrane domain M HAD-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Dihydropteroate synthetase-like Methionine synthase domain 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Class II aaRS and biotin synthetases Translation proteins 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Macro domain-like Zn-dependent exopeptidases 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
P-loop containing nucleoside triphosphate hydrolases Dehydroquinate synthase-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Tricorn protease N-terminal domain ClpP/crotonase 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
L30e-like alpha/beta knot 11
Activating enzymes of the ubiquitin-like proteins JAB1/MPN domain 11
Class I glutamine amidotransferase-like Homeodomain-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Phase 1 flagellin Phase 1 flagellin 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Ribonuclease H-like Porins 11
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
beta-N-acetylhexosaminidase-like domain (Trans)glycosidases 11
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 11
Nucleic acid-binding proteins GAD domain-like 11
Ferritin-like MFS general substrate transporter 11
CheY-like P-loop containing nucleoside triphosphate hydrolases 11
beta-Roll beta-Roll 11
Radical SAM enzymes RuvA domain 2-like 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
TGS-like Class II aaRS and biotin synthetases 11
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 11
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
"Winged helix" DNA-binding domain HRDC-like 11
Eukaryotic type KH-domain (KH-domain type I) P-loop containing nucleoside triphosphate hydrolases 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Tricorn protease domain 2 PDZ domain-like 11
Hsp33 domain HSP33 redox switch-like 11
Aldolase SIS domain 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Periplasmic binding protein-like II MetI-like 11
Cupredoxins Cupredoxins 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Clc chloride channel CBS-domain pair 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
PA domain Zn-dependent exopeptidases 11
Galactose mutarotase-like E set domains 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Nucleotidyltransferase ACT-like 11
Acyl-CoA N-acyltransferases (Nat) Ribulose-phoshate binding barrel 11
Nucleotidyltransferase TGS-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
RmlC-like cupins Homeodomain-like 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Zinc beta-ribbon DNA primase core 11
CheY-like Homeodomain-like 11
DNA-glycosylase Nudix 11
Cobalamin (vitamin B12)-binding domain Radical SAM enzymes 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
Methionine synthase domain Methionine synthase activation domain-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
Nucleic acid-binding proteins BRCT domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
ISP domain FAD/NAD(P)-binding domain 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Tricorn protease N-terminal domain Tricorn protease domain 2 11
Single hybrid motif Thiamin diphosphate-binding fold (THDP-binding) 11
Globin-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
TolA/TonB C-terminal domain TolA/TonB C-terminal domain 11
PUA domain-like alpha/beta knot 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
DNA methylase specificity domain DNA methylase specificity domain 11
HAMP domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Globin-like Riboflavin synthase domain-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Acyl-CoA N-acyltransferases (Nat) Nudix 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Arabinanase/levansucrase/invertase Arabinanase/levansucrase/invertase 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
(Trans)glycosidases Glycosyl hydrolase domain 11
Phage tail proteins Phage tail proteins 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
lambda repressor-like DNA-binding domains RmlC-like cupins 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Ribonuclease H-like HRDC-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
RuvA domain 2-like BRCT domain 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases GAD domain-like 11
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Thioredoxin-like TPR-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Translation proteins Ribosomal protein S5 domain 2-like 11
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
GAF domain-like Homodimeric domain of signal transducing histidine kinase 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
DAK1/DegV-like DhaL-like 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
GroES-like GroES-like 11
CarD-like TRCF domain-like 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Nucleotide-binding domain Nucleotide-binding domain 11
Inosine monophosphate dehydrogenase (IMPDH) Nitrite and sulphite reductase 4Fe-4S domain-like 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
Nucleotide-diphospho-sugar transferases Phosphoglucomutase, first 3 domains 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
YrdC/RibB RibA-like 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
YlxR-like L30e-like 11
Tricorn protease N-terminal domain PDZ domain-like 11
"Winged helix" DNA-binding domain GAF domain-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
YjeF N-terminal domain-like Ribokinase-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Metallo-hydrolase/oxidoreductase Metallo-hydrolase/oxidoreductase 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
PreATP-grasp domain PreATP-grasp domain 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
Ribonuclease H-like DNA/RNA polymerases 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
HCP-like HCP-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Translation proteins Translation proteins 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Nucleotide-diphospho-sugar transferases Phosphoglucomutase, C-terminal domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Origin of replication-binding domain, RBD-like P-loop containing nucleoside triphosphate hydrolases 11
HD-domain/PDEase-like ACT-like 11
Voltage-gated potassium channels E set domains 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
beta-lactamase/transpeptidase-like D-aminopeptidase, middle and C-terminal domains 11
CheY-like CheY-like 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
DNase I-like Hedgehog/intein (Hint) domain 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
GAF domain-like Homeodomain-like 11
Bacterial muramidases Lysozyme-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Carbamate kinase-like PUA domain-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Nucleic acid-binding proteins PheT/TilS domain 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
PHP14-like Phospholipase D/nuclease 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
TGS-like Class II aaRS ABD-related 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
TerB-like Chaperone J-domain 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
P-loop containing nucleoside triphosphate hydrolases alpha/beta-Hydrolases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
GroEL-intermediate domain like GroEL apical domain-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Acetyl-CoA synthetase-like Thioesterase/thiol ester dehydrase-isomerase 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
PPK N-terminal domain-like PHP14-like 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
DNase I-like UDP-Glycosyltransferase/glycogen phosphorylase 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
Thiolase-like Thiolase-like 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
MetI-like MetI-like 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
cAMP-binding domain-like "Winged helix" DNA-binding domain 11
Ribokinase-like Nucleotidylyl transferase 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Tricorn protease domain 2 ClpP/crotonase 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
PIN domain-like Ribonuclease H-like 11
Heme-dependent catalase-like Class I glutamine amidotransferase-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 11
PIN domain-like DNA/RNA polymerases 11
S-adenosyl-L-methionine-dependent methyltransferases P-loop containing nucleoside triphosphate hydrolases 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
HMA, heavy metal-associated domain HAD-like 11
PH0987 N-terminal domain-like Cyclophilin-like 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
CheC-like Surface presentation of antigens (SPOA) 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
Tetrahydrobiopterin biosynthesis enzymes-like 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
GroEL equatorial domain-like GroEL apical domain-like 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
DNA topoisomerase I domain DNA breaking-rejoining enzymes 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
FAD-linked oxidoreductase ALDH-like 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
GAF domain-like Nucleotide cyclase 11
CheY-like Methylesterase CheB, C-terminal domain 11
PheT/TilS domain Putative DNA-binding domain 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Translation proteins ThrRS/AlaRS common domain 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
TGS-like ThrRS/AlaRS common domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Calcium ATPase, transduction domain A HAD-like 11
Periplasmic binding protein-like II ACT-like 11
FliG FliG 11
ACT-like Formyltransferase 11
Hedgehog/intein (Hint) domain UDP-Glycosyltransferase/glycogen phosphorylase 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Carbamate kinase-like ACT-like 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
HD-domain/PDEase-like TGS-like 11
Thioredoxin-like Thioredoxin-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Nucleotidylyl transferase tRNA-binding arm 11

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