SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Nitrosomonas europaea ATCC 19718

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

608 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 253
Homeodomain-like Ribonuclease H-like 231
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2111
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 126
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 105
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 94
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 94
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 94
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 93
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 94
Actin-like ATPase domain Actin-like ATPase domain 93
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 84
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 82
P-loop containing nucleoside triphosphate hydrolases Translation proteins 85
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 73
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 74
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 74
Cupredoxins Cupredoxins 76
Cytochrome c Cytochrome c 74
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 73
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 64
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 65
TPR-like TPR-like 66
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 52
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 54
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 55
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 51
PLP-binding barrel Alanine racemase C-terminal domain-like 42
CheY-like Homeodomain-like 41
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 42
Translation proteins EF-G C-terminal domain-like 43
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 43
PurM N-terminal domain-like PurM C-terminal domain-like 42
Nucleotide cyclase EAL domain-like 44
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 41
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 42
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 43
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 43
CheY-like C-terminal effector domain of the bipartite response regulators 41
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 43
Thioredoxin-like GST C-terminal domain-like 41
GroES-like NAD(P)-binding Rossmann-fold domains 43
CheY-like P-loop containing nucleoside triphosphate hydrolases 41
Alpha-L RNA-binding motif Pseudouridine synthase 41
Triger factor/SurA peptide-binding domain-like FKBP-like 44
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 42
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 43
PreATP-grasp domain Rudiment single hybrid motif 42
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 33
Thiolase-like Thiolase-like 31
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
HAD-like Calcium ATPase, transmembrane domain M 33
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 32
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 31
Calcium ATPase, transduction domain A HAD-like 33
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 33
PYP-like sensor domain (PAS domain) CheY-like 33
Nucleic acid-binding proteins RuvA domain 2-like 33
Phospholipase D/nuclease Phospholipase D/nuclease 32
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 33
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 33
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 32
P-loop containing nucleoside triphosphate hydrolases MOP-like 31
HAMP domain-like PYP-like sensor domain (PAS domain) 33
Resolvase-like Homeodomain-like 31
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 33
PYP-like sensor domain (PAS domain) EAL domain-like 33
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 32
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
DNA methylase specificity domain DNA methylase specificity domain 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 33
CheY-like EAL domain-like 33
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 33
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 22
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
C-terminal effector domain of the bipartite response regulators TPR-like 22
CheY-like Histidine-containing phosphotransfer domain, HPT domain 22
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 22
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, catalytic domain 22
PYP-like sensor domain (PAS domain) Nucleotide cyclase 22
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 21
Nucleotidylyl transferase Ribosomal protein L25-like 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
PDZ domain-like PDZ domain-like 22
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 22
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Cyclophilin-like Single hybrid motif 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
ACT-like ACT-like 22
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 22
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 21
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 21
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 22
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 21
cAMP-binding domain-like "Winged helix" DNA-binding domain 21
CBS-domain pair FAD-binding/transporter-associated domain-like 21
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 22
Cyclophilin-like PH0987 N-terminal domain-like 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 22
PH0987 N-terminal domain-like Single hybrid motif 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 22
L30e-like alpha/beta knot 21
Class I glutamine amidotransferase-like Homeodomain-like 21
HAMP domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 22
Trypsin-like serine proteases PDZ domain-like 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
CheY-like Nucleotide cyclase 22
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Cyclophilin-like Cyclophilin-like 22
GAF domain-like PYP-like sensor domain (PAS domain) 22
GAF domain-like CheY-like 22
MetI-like MetI-like 21
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 21
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 21
HAMP domain-like Nucleotide cyclase 22
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
TPR-like HCP-like 22
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Fic-like "Winged helix" DNA-binding domain 21
HlyD-like secretion proteins HlyD-like secretion proteins 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
Histidine-containing phosphotransfer domain, HPT domain CheW-like 22
Single hybrid motif CoA-dependent acyltransferases 22
Folate-binding domain Aminomethyltransferase beta-barrel domain 21
PUA domain-like Ribosomal protein S5 domain 2-like 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 21
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Chorismate mutase II Periplasmic binding protein-like II 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
SAM/Pointed domain P-loop containing nucleoside triphosphate hydrolases 11
ISP domain Bet v1-like 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
PGBD-like L,D-transpeptidase catalytic domain-like 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases UDP-Glycosyltransferase/glycogen phosphorylase 11
NE0471 N-terminal domain-like lambda repressor-like DNA-binding domains 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
CBS-domain pair AFP III-like domain 11
MesJ substrate recognition domain-like PheT/TilS domain 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
TGS-like Class II aaRS ABD-related 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
S-adenosyl-L-methionine-dependent methyltransferases GroES-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 11
SAM/Pointed domain Nucleotide cyclase 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
PurS-like PurM C-terminal domain-like 11
Translation proteins PRC-barrel domain 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
HCP-like Porins 11
Barwin-like endoglucanases Sporulation related repeat 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
HD-domain/PDEase-like P-loop containing nucleoside triphosphate hydrolases 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
FAD/NAD(P)-binding domain Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Homocysteine S-methyltransferase Methionine synthase domain 11
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
TGS-like ACT-like 11
Di-copper centre-containing domain Collagen-binding domain 11
PUA domain-like alpha/beta knot 11
Translation proteins Translation proteins 11
Carbamate kinase-like PUA domain-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
ClpP/crotonase NfeD domain-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Chelatase Chelatase 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
CBS-domain pair Aldolase 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 11
PurS-like PurM N-terminal domain-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Ribonuclease H-like RuvA domain 2-like 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Adenine nucleotide alpha hydrolases-like Protein kinase-like (PK-like) 11
HprK N-terminal domain-like PEP carboxykinase-like 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
Lysozyme-like LysM domain 11
FabD/lysophospholipase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
TGS-like Class II aaRS and biotin synthetases 11
Nucleotidyltransferase TGS-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Thiolase-like NAD(P)-binding Rossmann-fold domains 11
CheC-like Surface presentation of antigens (SPOA) 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Nucleic acid-binding proteins BRCT domain 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
HMA, heavy metal-associated domain HAD-like 11
HCP-like HCP-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
PreATP-grasp domain Methylglyoxal synthase-like 11
SAM/Pointed domain TPR-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
LysM domain LysM domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
NAD(P)-binding Rossmann-fold domains ACP-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Rudiment single hybrid motif Single hybrid motif 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Thioredoxin-like Six-hairpin glycosidases 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
GAF domain-like EAL domain-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
CarD-like TRCF domain-like 11
Bacterial muramidases Lysozyme-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Periplasmic binding protein-like II ACT-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
CheY-like Methylesterase CheB, C-terminal domain 11
Collagen-binding domain Collagen-binding domain 11
Methyl-accepting chemotaxis protein (MCP) signaling domain Methyl-accepting chemotaxis protein (MCP) signaling domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
FKBP-like FKBP-like 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
PreATP-grasp domain Cyclophilin-like 11
RuBisCO, large subunit, small (N-terminal) domain RuBisCo, C-terminal domain 11
DinB/YfiT-like putative metalloenzymes S-adenosyl-L-methionine-dependent methyltransferases 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
PDZ domain-like ClpP/crotonase 11
C-type lectin-like S-adenosyl-L-methionine-dependent methyltransferases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
PIN domain-like Ribonuclease H-like 11
GroES-like ACP-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Pectin lyase-like Autotransporter 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
PIN domain-like DNA/RNA polymerases 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
alpha/beta-Hydrolases Subtilisin-like 11
(Trans)glycosidases Glycosyl hydrolase domain 11
Glutathione synthetase ATP-binding domain-like Cyclophilin-like 11
P-loop containing nucleoside triphosphate hydrolases TPR-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
CBS-domain pair MgtE membrane domain-like 11
Ribonuclease H-like DNA/RNA polymerases 11
ISP domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Thiolase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Aldolase AFP III-like domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
CheW-like CheW-like 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
FAD/NAD(P)-binding domain Riboflavin synthase domain-like 11
Ribosomal protein L6 Ribosomal protein L6 11
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
LysM domain Duplicated hybrid motif 11
PreATP-grasp domain PH0987 N-terminal domain-like 11
Macro domain-like Zn-dependent exopeptidases 11
Nucleotidyltransferase Nucleotidyltransferase 11
GroEL equatorial domain-like GroEL apical domain-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
FabD/lysophospholipase-like ACP-like 11
P-loop containing nucleoside triphosphate hydrolases HCP-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Glycoside hydrolase/deacetylase Galactose mutarotase-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Peptide methionine sulfoxide reductase Thioredoxin-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Putative DNA-binding domain LexA/Signal peptidase 11
GAF domain-like Nucleotide cyclase 11
6-phosphogluconate dehydrogenase C-terminal domain-like ClpP/crotonase 11
GAF domain-like Homodimeric domain of signal transducing histidine kinase 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
GAF domain-like HAMP domain-like 11
Thiolase-like GroES-like 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
PRTase-like PRTase-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
YajQ-like YajQ-like 11
HD-domain/PDEase-like ACT-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
PreATP-grasp domain PreATP-grasp domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Carbamate kinase-like ACT-like 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
CheW-like CheY-like 11
Metalloproteases ("zincins"), catalytic domain Zn-dependent exopeptidases 11
Nucleotide cyclase P-loop containing nucleoside triphosphate hydrolases 11
UROD/MetE-like UROD/MetE-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
FliG FliG 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
TPR-like Porins 11
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 11
Thioredoxin-like Mss4-like 11
Nudix Thiamin phosphate synthase 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
E set domains Glycosyl hydrolase domain 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
MgtE N-terminal domain-like CBS-domain pair 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
Nucleotide cyclase Nucleotide cyclase 11
EreA/ChaN-like PDZ domain-like 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 11
ISP domain FAD/NAD(P)-binding domain 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
CheY-like CheY-like 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
UDP-Glycosyltransferase/glycogen phosphorylase HAD-like 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Tex N-terminal region-like Ribonuclease H-like 11
Nucleotidylyl transferase tRNA-binding arm 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
AFP III-like domain Xylose isomerase-like 11
Nucleotidyltransferase ACT-like 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Translation proteins ThrRS/AlaRS common domain 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Thiolase-like FabD/lysophospholipase-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
PheT/TilS domain Putative DNA-binding domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Rhodanese/Cell cycle control phosphatase P-loop containing nucleoside triphosphate hydrolases 11
DNA-glycosylase Nudix 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
HAMP domain-like CheY-like 11
Actin-like ATPase domain HD-domain/PDEase-like 11
HD-domain/PDEase-like Nucleotide cyclase 11
HCP-like Lysozyme-like 11
Single hybrid motif FAD/NAD(P)-binding domain 11
GAF domain-like EspE N-terminal domain-like 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
GroEL-intermediate domain like GroEL apical domain-like 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
GIY-YIG endonuclease RuvA domain 2-like 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase GroES-like 11
RuvA domain 2-like RuvA domain 2-like 11
GroES-like GroES-like 11
HMA, heavy metal-associated domain FAD/NAD(P)-binding domain 11
HMA, heavy metal-associated domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Cupredoxins Nitrous oxide reductase, N-terminal domain 11
Galactose mutarotase-like E set domains 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
E set domains (Trans)glycosidases 11
PurS-like Class I glutamine amidotransferase-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Formyltransferase FMT C-terminal domain-like 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
DPP6 N-terminal domain-like DPP6 N-terminal domain-like 11
RuvA domain 2-like BRCT domain 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 11
Methionine synthase domain Methionine synthase activation domain-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Thiolase-like ACP-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 11
DNA clamp DNA clamp 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
TGS-like ThrRS/AlaRS common domain 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
Flavoproteins Riboflavin synthase domain-like 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
Glutathione synthetase ATP-binding domain-like PH0987 N-terminal domain-like 11
GAF domain-like Histidine-containing phosphotransfer domain, HPT domain 11
CoA-transferase family III (CaiB/BaiF) CoA-transferase family III (CaiB/BaiF) 11
Zinc beta-ribbon DNA primase core 11
Pseudouridine synthase PUA domain-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
PurS-like FGAM synthase PurL, linker domain 11
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, peptide-binding domain 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Nucleic acid-binding proteins PheT/TilS domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
HD-domain/PDEase-like Nucleotidyltransferase 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Aldolase Xylose isomerase-like 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
S-adenosyl-L-methionine-dependent methyltransferases ACP-like 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase S-adenosyl-L-methionine-dependent methyltransferases 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Nucleic acid-binding proteins GAD domain-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Metalloproteases ("zincins"), catalytic domain PDZ domain-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
PreATP-grasp domain Single hybrid motif 11
Zn-dependent exopeptidases PDZ domain-like 11
Lysozyme-like PGBD-like 11
DinB/YfiT-like putative metalloenzymes C-type lectin-like 11
PHP14-like Phospholipase D/nuclease 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Cytochrome c Thioredoxin-like 11
RNase III domain-like dsRNA-binding domain-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
YrdC/RibB RibA-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
HAMP domain-like EAL domain-like 11
Nucleotide cyclase TPR-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Nucleotide-diphospho-sugar transferases UDP-Glycosyltransferase/glycogen phosphorylase 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
"Winged helix" DNA-binding domain C-terminal domain of transcriptional repressors 11
Chorismate mutase II ACT-like 11
NAD(P)-binding Rossmann-fold domains ClpP/crotonase 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
P-loop containing nucleoside triphosphate hydrolases PRTase-like 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
HD-domain/PDEase-like TGS-like 11
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 11
Ribonuclease H-like Nucleic acid-binding proteins 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
YjeF N-terminal domain-like Ribokinase-like 11
"Winged helix" DNA-binding domain GAF domain-like 11
FabD/lysophospholipase-like GroES-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Putative DNA-binding domain Translation proteins 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
DNA primase core DNA primase DnaG, C-terminal domain 11
Class II aaRS and biotin synthetases GAD domain-like 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
CBS-domain pair Xylose isomerase-like 11
Rudiment single hybrid motif Cyclophilin-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 11
Tex N-terminal region-like RuvA domain 2-like 11
Rudiment single hybrid motif PH0987 N-terminal domain-like 11
PPK N-terminal domain-like PHP14-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Homodimeric domain of signal transducing histidine kinase CheY-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Peptide methionine sulfoxide reductase Mss4-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11

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