SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Babela massiliensis

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

202 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Ankyrin repeat Ankyrin repeat 198
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 97
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 55
P-loop containing nucleoside triphosphate hydrolases Translation proteins 44
Immunoglobulin Immunoglobulin 44
Class II aaRS and biotin synthetases Class II aaRS ABD-related 43
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 33
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Actin-like ATPase domain Actin-like ATPase domain 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
L30e-like alpha/beta knot 21
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 22
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 22
PUA domain-like Ribosomal protein S5 domain 2-like 22
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 22
Translation proteins ThrRS/AlaRS common domain 22
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 22
Trypsin-like serine proteases PDZ domain-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 22
Translation proteins EF-G C-terminal domain-like 22
Nucleic acid-binding proteins Nucleic acid-binding proteins 22
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 22
Alpha-L RNA-binding motif Pseudouridine synthase 21
FAD/NAD(P)-binding domain Thioredoxin-like 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
3-carboxy-cis,cis-mucoante lactonizing enzyme Immunoglobulin 22
PDZ domain-like PDZ domain-like 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
PKD domain Immunoglobulin 22
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
HAD-like Calcium ATPase, transmembrane domain M 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
F1F0 ATP synthase subunit C F1F0 ATP synthase subunit C 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Ankyrin repeat beta-beta-alpha zinc fingers 11
Ribosomal protein L6 Ribosomal protein L6 11
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
Class II aaRS and biotin synthetases GAD domain-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
CBS-domain pair FAD-binding/transporter-associated domain-like 11
Zinc beta-ribbon Zinc beta-ribbon 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Zinc beta-ribbon DNA primase core 11
Class II aaRS and biotin synthetases Translation proteins 11
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Class II aaRS ABD-related C-terminal domain of ProRS 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 11
Nucleotidylyl transferase P-loop containing nucleoside triphosphate hydrolases 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases MOP-like 11
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
PIN domain-like Ribonuclease H-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
TolB, C-terminal domain Immunoglobulin 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Pectin lyase-like Immunoglobulin 11
PKD domain PKD domain 11
Putative isomerase YbhE PKD domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Nucleic acid-binding proteins GAD domain-like 11
lambda repressor-like DNA-binding domains LexA/Signal peptidase 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
P-loop containing nucleoside triphosphate hydrolases Glucocorticoid receptor-like (DNA-binding domain) 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Ribonuclease H-like DNA/RNA polymerases 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
PIN domain-like DNA/RNA polymerases 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
MgtE N-terminal domain-like CBS-domain pair 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Calcium ATPase, transduction domain A HAD-like 11
Macro domain-like Zn-dependent exopeptidases 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Translation proteins Ribosomal protein S5 domain 2-like 11
3-carboxy-cis,cis-mucoante lactonizing enzyme TolB, C-terminal domain 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
PUA domain-like Nucleotidylyl transferase 11
Putative isomerase YbhE Immunoglobulin 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
GatB/YqeY motif GatB/YqeY motif 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
PheT/TilS domain Putative DNA-binding domain 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
RuvA domain 2-like P-loop containing nucleoside triphosphate hydrolases 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
ATP-dependent DNA ligase DNA-binding domain DNA ligase/mRNA capping enzyme, catalytic domain 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Integrin alpha N-terminal domain Pili subunits 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
CBS-domain pair MgtE membrane domain-like 11
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Translation proteins Translation proteins 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
GroEL equatorial domain-like GroEL equatorial domain-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 11
PDZ domain-like ClpP/crotonase 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
ATP-dependent DNA ligase DNA-binding domain Nucleic acid-binding proteins 11
GroES-like NAD(P)-binding Rossmann-fold domains 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Nucleotidyltransferase PAP/OAS1 substrate-binding domain 11
Chaperone J-domain HSP40/DnaJ peptide-binding domain 11
Nucleic acid-binding proteins RuvA domain 2-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
TROVE domain-like vWA-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Rad50 coiled-coil Zn hook 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 11
Metallo-dependent phosphatases Periplasmic binding protein-like I 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
DNA clamp DNA clamp 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Class II aaRS and biotin synthetases C-terminal domain of ProRS 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Pectin lyase-like PKD domain 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 11
GroEL equatorial domain-like GroEL apical domain-like 11
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11

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