SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Sulfurimonas denitrificans DSM 1251

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

502 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 3115
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 1711
Nucleotide cyclase EAL domain-like 1610
PYP-like sensor domain (PAS domain) Nucleotide cyclase 1110
CheY-like C-terminal effector domain of the bipartite response regulators 102
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 109
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 97
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 93
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 97
Homodimeric domain of signal transducing histidine kinase CheY-like 98
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 86
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 86
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 86
Actin-like ATPase domain Actin-like ATPase domain 84
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 86
P-loop containing nucleoside triphosphate hydrolases Translation proteins 76
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 64
PurM N-terminal domain-like PurM C-terminal domain-like 62
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 65
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 62
PYP-like sensor domain (PAS domain) EAL domain-like 65
PYP-like sensor domain (PAS domain) CheY-like 65
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 65
Cytochrome c Cytochrome c 63
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 53
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 52
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 53
CheY-like Nucleotide cyclase 44
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 43
CheY-like Histidine-containing phosphotransfer domain, HPT domain 44
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 44
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 43
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 44
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 44
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 42
PLP-binding barrel Alanine racemase C-terminal domain-like 42
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
cAMP-binding domain-like "Winged helix" DNA-binding domain 41
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 31
PreATP-grasp domain Rudiment single hybrid motif 32
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 32
Class II aaRS and biotin synthetases Class II aaRS ABD-related 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
CheW-like CheY-like 32
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 31
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 31
FAD/NAD(P)-binding domain HI0933 insert domain-like 31
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 33
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 33
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 32
Nucleic acid-binding proteins RuvA domain 2-like 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
Sensory domain-like Nucleotide cyclase 33
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 32
HCP-like HCP-like 32
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 32
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 31
Translation proteins EF-G C-terminal domain-like 32
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 33
Alpha-L RNA-binding motif Pseudouridine synthase 31
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 31
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 22
Calcium ATPase, transduction domain A HAD-like 22
S-adenosyl-L-methionine-dependent methyltransferases P-loop containing nucleoside triphosphate hydrolases 21
Nucleic acid-binding proteins Nucleic acid-binding proteins 22
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 21
vWA-like TPR-like 22
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 22
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
MOP-like MOP-like 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 22
alpha-helical ferredoxin Nucleotide-binding domain 22
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 22
MgtE N-terminal domain-like CBS-domain pair 21
PDZ domain-like PDZ domain-like 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
CheC-like Surface presentation of antigens (SPOA) 22
Aldolase post-HMGL domain-like 22
Nucleotide-binding domain Nucleotide-binding domain 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 22
TT1751-like TT1751-like 22
HAD-like Calcium ATPase, transmembrane domain M 22
CBS-domain pair MgtE membrane domain-like 21
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 21
GAF domain-like Nucleotide cyclase 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Enolase N-terminal domain-like Enolase C-terminal domain-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Periplasmic binding protein-like II PYP-like sensor domain (PAS domain) 22
HD-domain/PDEase-like Nucleotidyltransferase 22
Phospholipase D/nuclease Phospholipase D/nuclease 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 22
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 22
Nitrous oxide reductase, N-terminal domain Cupredoxins 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
Cupredoxins Cytochrome c 21
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 22
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 22
2Fe-2S ferredoxin-like alpha-helical ferredoxin 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
CheY-like EAL domain-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 22
Ribokinase-like Nucleotidylyl transferase 22
Voltage-gated potassium channels TrkA C-terminal domain-like 22
Nitrous oxide reductase, N-terminal domain Cytochrome c 21
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Homodimeric domain of signal transducing histidine kinase CheW-like 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 21
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 21
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 22
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 22
MgtE N-terminal domain-like MgtE membrane domain-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 22
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 22
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 22
ACT-like ACT-like 22
Periplasmic binding protein-like II Periplasmic binding protein-like II 22
Histidine-containing phosphotransfer domain, HPT domain CheW-like 22
DNA methylase specificity domain DNA methylase specificity domain 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
L30e-like alpha/beta knot 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
Formyltransferase FMT C-terminal domain-like 22
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 22
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 21
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
post-HMGL domain-like Single hybrid motif 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
C-type lectin-like S-adenosyl-L-methionine-dependent methyltransferases 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Thiolase-like Thiolase-like 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
NAD(P)-binding Rossmann-fold domains Citrate synthase 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Nucleic acid-binding proteins BRCT domain 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Carbamate kinase-like ACT-like 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 11
Chorismate mutase II Periplasmic binding protein-like II 11
Nqo1C-terminal domain-like Nucleotide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 11
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Zinc beta-ribbon DNA primase core 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Metallo-hydrolase/oxidoreductase GAF domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Nucleotidyltransferase TGS-like 11
DNA clamp DNA clamp 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Thioredoxin-like Six-hairpin glycosidases 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
YrdC/RibB RibA-like 11
Sensory domain-like EAL domain-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
CBS-domain pair Nucleotide-diphospho-sugar transferases 11
Metallo-hydrolase/oxidoreductase Homodimeric domain of signal transducing histidine kinase 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
PheT/TilS domain Putative DNA-binding domain 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
YajQ-like YajQ-like 11
HisI-like all-alpha NTP pyrophosphatases 11
Ribonuclease H-like Nucleic acid-binding proteins 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
GroEL equatorial domain-like GroEL apical domain-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Globin-like Homodimeric domain of signal transducing histidine kinase 11
Barwin-like endoglucanases Sporulation related repeat 11
LeuD/IlvD-like Aconitase iron-sulfur domain 11
SufE/NifU Fe-S cluster assembly (FSCA) domain-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Acyl-CoA N-acyltransferases (Nat) Carbon-nitrogen hydrolase 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Zinc beta-ribbon Zinc beta-ribbon 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Ferredoxin thioredoxin reductase (FTR), catalytic beta chain Rhodanese/Cell cycle control phosphatase 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
CheY-like CheY-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Globin-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
"Winged helix" DNA-binding domain MOP-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
UROD/MetE-like UROD/MetE-like 11
PHP domain-like AF1531-like 11
HD-domain/PDEase-like ACT-like 11
4Fe-4S ferredoxins NosL/MerB-like 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
ACT-like Formyltransferase 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Periplasmic binding protein-like II ACT-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
GAF domain-like PYP-like sensor domain (PAS domain) 11
Translation proteins PRC-barrel domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 11
FKBP-like Triger factor/SurA peptide-binding domain-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
beta-Roll beta-Roll 11
Acyl-CoA N-acyltransferases (Nat) Arginase/deacetylase 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
CheY-like P-loop containing nucleoside triphosphate hydrolases 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
GroEL-intermediate domain like GroEL apical domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
NosL/MerB-like NosL/MerB-like 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
FAD-linked oxidoreductase ALDH-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheC-like 11
(Trans)glycosidases Nucleotide-diphospho-sugar transferases 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Metallo-hydrolase/oxidoreductase Flavoproteins 11
Nucleotide cyclase Nucleotide cyclase 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
4Fe-4S ferredoxins ADC-like 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
Metallo-hydrolase/oxidoreductase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
Translation proteins ThrRS/AlaRS common domain 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
4Fe-4S ferredoxins 4Fe-4S ferredoxins 11
UbiD C-terminal domain-like UbiD C-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Cytochrome c C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase 11
Nucleotidyltransferase ACT-like 11
"Winged helix" DNA-binding domain HRDC-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 11
PIN domain-like DNA/RNA polymerases 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
PIN domain-like Ribonuclease H-like 11
Ribonuclease H-like RuvA domain 2-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Class II aaRS and biotin synthetases Translation proteins 11
Aldolase Single hybrid motif 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Hemerythrin-like Nucleotide cyclase 11
RNase III domain-like dsRNA-binding domain-like 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Fibronectin type III Fibronectin type III 11
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Ribonuclease H-like DNA/RNA polymerases 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
OMPA-like TSP type-3 repeat 11
HD-domain/PDEase-like TGS-like 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Nqo1C-terminal domain-like alpha-helical ferredoxin 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
Trypsin-like serine proteases CalX-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Oxidoreductase molybdopterin-binding domain E set domains 11
TSP type-3 repeat OmpA-like 11
HCP-like Outer membrane phospholipase A (OMPLA) 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
HMA, heavy metal-associated domain HAD-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Translation proteins "Winged helix" DNA-binding domain 11
PHP14-like Phospholipase D/nuclease 11
Chorismate mutase II ACT-like 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
GAF domain-like HD-domain/PDEase-like 11
Globin-like CheY-like 11
Ferritin-like Rubredoxin-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
CheY-like Methylesterase CheB, C-terminal domain 11
Aldolase AFP III-like domain 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
alpha-helical ferredoxin alpha-helical ferredoxin 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 11
TPR-like Porins 11
Trypsin-like serine proteases Type III secretory system chaperone-like 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
FMT C-terminal domain-like ClpP/crotonase 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Periplasmic binding protein-like II Lysozyme-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Formyltransferase ClpP/crotonase 11
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
Metallo-hydrolase/oxidoreductase HD-domain/PDEase-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Periplasmic binding protein-like II CheY-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
AraD/HMP-PK domain-like NAD(P)-binding Rossmann-fold domains 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Serine metabolism enzymes domain ACT-like 11
OMPA-like OmpA-like 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
Lysozyme-like LysM domain 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
CheY-like HD-domain/PDEase-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Hemerythrin-like PYP-like sensor domain (PAS domain) 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Nucleic acid-binding proteins GAD domain-like 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
cAMP-binding domain-like CBS-domain pair 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Sensory domain-like PYP-like sensor domain (PAS domain) 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Hemerythrin-like EAL domain-like 11
Homeodomain-like Homeodomain-like 11
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Nucleotidylyl transferase tRNA-binding arm 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Tex N-terminal region-like RuvA domain 2-like 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain "Winged helix" DNA-binding domain 11
Periplasmic binding protein-like II Histidine-containing phosphotransfer domain, HPT domain 11
L,D-transpeptidase catalytic domain-like NTF2-like 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Ribosomal protein L6 Ribosomal protein L6 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Trypsin-like serine proteases PDZ domain-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Macro domain-like Zn-dependent exopeptidases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
FliG FliG 11
PDZ domain-like ClpP/crotonase 11
Translation proteins Translation proteins 11
Origin of replication-binding domain, RBD-like P-loop containing nucleoside triphosphate hydrolases 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
C-terminal effector domain of the bipartite response regulators PYP-like sensor domain (PAS domain) 11
Nucleic acid-binding proteins PheT/TilS domain 11
YjeF N-terminal domain-like Ribokinase-like 11
HCP-like TPR-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
CarD-like TRCF domain-like 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
NTF2-like Sec-C motif 11
Resolvase-like Homeodomain-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Homeodomain-like Probable bacterial effector-binding domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
PreATP-grasp domain PreATP-grasp domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Mss4-like Peptide methionine sulfoxide reductase 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
GAF domain-like EAL domain-like 11
ACP-like Glycerol-3-phosphate (1)-acyltransferase 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Restriction endonuclease-like Restriction endonuclease-like 11
PUA domain-like Nucleotidylyl transferase 11
RuvA domain 2-like BRCT domain 11
Trigger factor ribosome-binding domain FKBP-like 11
RuvA domain 2-like RuvA domain 2-like 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
PPK N-terminal domain-like PHP14-like 11
Tex N-terminal region-like Ribonuclease H-like 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
HD-domain/PDEase-like HD-domain/PDEase-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
2Fe-2S ferredoxin-like ADC-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11

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