SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Acidithiobacillus ferrooxidans ATCC 53993

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

563 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2413
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 141
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 134
HAD-like Calcium ATPase, transmembrane domain M 134
Calcium ATPase, transduction domain A HAD-like 134
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 134
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 136
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 124
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 113
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 113
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 113
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 113
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 102
P-loop containing nucleoside triphosphate hydrolases Translation proteins 96
Actin-like ATPase domain Actin-like ATPase domain 83
CheY-like Homeodomain-like 82
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 82
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 84
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 74
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 72
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 73
CheY-like P-loop containing nucleoside triphosphate hydrolases 71
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 63
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 64
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 63
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Thioredoxin-like GST C-terminal domain-like 61
CheY-like C-terminal effector domain of the bipartite response regulators 62
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 52
DNA methylase specificity domain DNA methylase specificity domain 52
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 53
Alpha-L RNA-binding motif Pseudouridine synthase 51
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 52
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 53
NAD(P)-binding Rossmann-fold domains GroES-like 53
ACT-like ACT-like 54
Ribosomal protein S5 domain 2-like P-loop containing nucleoside triphosphate hydrolases 54
Phospholipase D/nuclease Phospholipase D/nuclease 53
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 42
PurM N-terminal domain-like PurM C-terminal domain-like 42
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 43
TPR-like TPR-like 43
PDZ domain-like PDZ domain-like 42
RuBisCO, large subunit, small (N-terminal) domain RuBisCo, C-terminal domain 41
Cytochrome c Cytochrome c 42
Nucleotidyltransferase Poly A polymerase C-terminal region-like 43
cAMP-binding domain-like "Winged helix" DNA-binding domain 41
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 42
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 42
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 41
PreATP-grasp domain Rudiment single hybrid motif 41
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 41
Translation proteins EF-G C-terminal domain-like 43
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 32
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 32
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 32
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 33
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
Trypsin-like serine proteases PDZ domain-like 31
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 33
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 31
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 33
Triger factor/SurA peptide-binding domain-like FKBP-like 33
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Nucleotide cyclase EAL domain-like 33
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 32
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 31
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
PLP-binding barrel Alanine racemase C-terminal domain-like 32
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 31
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 31
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 32
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 32
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
HMA, heavy metal-associated domain FAD/NAD(P)-binding domain 33
PK beta-barrel domain-like PK C-terminal domain-like 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
Single hybrid motif CoA-dependent acyltransferases 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Carbamate kinase-like PUA domain-like 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 21
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 21
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 21
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 21
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 21
Galactose mutarotase-like Six-hairpin glycosidases 22
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 21
PYP-like sensor domain (PAS domain) EAL domain-like 22
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 21
Thiolase-like Thiolase-like 21
PYP-like sensor domain (PAS domain) Nucleotide cyclase 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 21
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
PUA domain-like Ribosomal protein S5 domain 2-like 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 22
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
NAD(P)-binding Rossmann-fold domains ACT-like 22
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 21
Lysozyme-like beta-lactamase/transpeptidase-like 22
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 21
Nucleotide-diphospho-sugar transferases RmlC-like cupins 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
"Winged helix" DNA-binding domain GAF domain-like 21
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 21
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 22
HlyD-like secretion proteins HlyD-like secretion proteins 22
Nucleotidyltransferase ACT-like 22
CBS-domain pair FAD-binding/transporter-associated domain-like 21
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 21
Nucleic acid-binding proteins RuvA domain 2-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 21
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
E set domains (Trans)glycosidases 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
GAF domain-like EAL domain-like 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
GAF domain-like Homeodomain-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Globin-like GAF domain-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
Flavoproteins Riboflavin synthase domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Hsp33 domain HSP33 redox switch-like 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
PurS-like Class I glutamine amidotransferase-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
UDP-Glycosyltransferase/glycogen phosphorylase HAD-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Homeodomain-like Homeodomain-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
FMN-dependent nitroreductase-like FMN-dependent nitroreductase-like 11
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
Radical SAM enzymes Nitrogenase accessory factor-like 11
GAF domain-like Homodimeric domain of signal transducing histidine kinase 11
HD-domain/PDEase-like TGS-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
(Trans)glycosidases Glycosyl hydrolase domain 11
Thiolase-like NAD(P)-binding Rossmann-fold domains 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 11
CoA-dependent acyltransferases FAD/NAD(P)-binding domain 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 11
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
TGS-like ACT-like 11
P-loop containing nucleoside triphosphate hydrolases MOP-like 11
SufE/NifU Fe-S cluster assembly (FSCA) domain-like 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
ClpP/crotonase ClpP/crotonase 11
Rhodanese/Cell cycle control phosphatase Ankyrin repeat 11
RuvA domain 2-like Nucleotidyltransferase 11
HMA, heavy metal-associated domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Homeodomain-like TATA-box binding protein-like 11
Actin-like ATPase domain HD-domain/PDEase-like 11
TGS-like Class II aaRS ABD-related 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
PIN domain-like DNA/RNA polymerases 11
Ribosomal protein L6 Ribosomal protein L6 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Nitrous oxide reductase, N-terminal domain Alkaline phosphatase-like 11
Nudix Thiamin phosphate synthase 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
FabD/lysophospholipase-like GroES-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Macro domain-like Zn-dependent exopeptidases 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
HMA, heavy metal-associated domain HAD-like 11
RuvA domain 2-like PHP domain-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
TGS-like Class II aaRS and biotin synthetases 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
Glycoside hydrolase/deacetylase Galactose mutarotase-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Serine metabolism enzymes domain ACT-like 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
TPR-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins BRCT domain 11
Single hybrid motif Single hybrid motif 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Nucleotide-binding domain Riboflavin synthase domain-like 11
DNA-glycosylase Nudix 11
HCP-like HCP-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
lambda repressor-like DNA-binding domains RmlC-like cupins 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
DNA repair protein MutS, domain III SMR domain-like 11
CoA-dependent acyltransferases FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
TATA-box binding protein-like DNA-glycosylase 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Fe-S cluster assembly (FSCA) domain-like ISP domain 11
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 11
GroEL equatorial domain-like GroEL apical domain-like 11
Nucleotidyltransferase TGS-like 11
SIS domain Nucleotidylyl transferase 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Clc chloride channel CBS-domain pair 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Galactose mutarotase-like E set domains 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
Aldolase post-HMGL domain-like 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Nucleotidylyl transferase P-loop containing nucleoside triphosphate hydrolases 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
ADP-ribosylglycohydrolase Thioredoxin-like 11
NAD(P)-binding Rossmann-fold domains ACP-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase GroES-like 11
FabD/lysophospholipase-like ACP-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
RmlC-like cupins RmlC-like cupins 11
Thiolase-like FabD/lysophospholipase-like 11
Periplasmic binding protein-like II ACT-like 11
Chorismate mutase II Periplasmic binding protein-like II 11
Nqo5-like HydB/Nqo4-like 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Thiolase-like ACP-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Formyltransferase FMT C-terminal domain-like 11
Putative DNA-binding domain Translation proteins 11
GroES-like GroES-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
RuvA domain 2-like JAB1/MPN domain 11
PreATP-grasp domain PreATP-grasp domain 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Nucleotidyltransferase PHP domain-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Bacterial muramidases Lysozyme-like 11
Restriction endonuclease-like Zinc beta-ribbon 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
HD-domain/PDEase-like ACT-like 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
FAD-linked oxidases, C-terminal domain FAD-linked oxidases, C-terminal domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
L30e-like alpha/beta knot 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Myosin rod fragments 11
Metalloproteases ("zincins"), catalytic domain PDZ domain-like 11
DNA clamp DNA clamp 11
GAF domain-like PYP-like sensor domain (PAS domain) 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Nucleic acid-binding proteins PheT/TilS domain 11
RuvA domain 2-like BRCT domain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Single hybrid motif FAD/NAD(P)-binding domain 11
TPR-like Periplasmic binding protein-like I 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Thiolase-like GroES-like 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
Nucleotidylyl transferase tRNA-binding arm 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
HprK N-terminal domain-like PEP carboxykinase-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Adhesin YadA, collagen-binding domain Pili subunits 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
E set domains E set domains 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
Barwin-like endoglucanases Sporulation related repeat 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
S-adenosyl-L-methionine-dependent methyltransferases PKD domain 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Protein kinase-like (PK-like) Zinc beta-ribbon 11
Pseudouridine synthase PUA domain-like 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Thioredoxin-like TPR-like 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
HisI-like all-alpha NTP pyrophosphatases 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Chorismate mutase II ACT-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
PHP domain-like P-loop containing nucleoside triphosphate hydrolases 11
YrdC/RibB RibA-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex FAD/NAD(P)-binding domain 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
PurS-like FGAM synthase PurL, linker domain 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
PYP-like sensor domain (PAS domain) Homeodomain-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
Ribonuclease H-like DNA/RNA polymerases 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
DNA polymerase beta, N-terminal domain-like PHP domain-like 11
Homeodomain-like Ribonuclease H-like 11
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
YajQ-like YajQ-like 11
SIS domain CBS-domain pair 11
Nucleotidyltransferase substrate binding subunit/domain Poly A polymerase C-terminal region-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 11
PUA domain-like alpha/beta knot 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
UROD/MetE-like UROD/MetE-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
E set domains Glycosyl hydrolase domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 11
TGS-like ThrRS/AlaRS common domain 11
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 11
Translation proteins Translation proteins 11
Nucleotidylyl transferase Riboflavin kinase-like 11
HD-domain/PDEase-like Nucleotidyltransferase 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) DNA-glycosylase 11
GIY-YIG endonuclease RuvA domain 2-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
PIN domain-like Ribonuclease H-like 11
FKBP-like FKBP-like 11
"Winged helix" DNA-binding domain Chorismate lyase-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
DNA polymerase beta, N-terminal domain-like RuvA domain 2-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
4Fe-4S ferredoxins Clavaminate synthase-like 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
YbjQ-like YbjQ-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
Aldolase Dimeric alpha+beta barrel 11
PurS-like PurM N-terminal domain-like 11
4Fe-4S ferredoxins ADC-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Globin-like EAL domain-like 11
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Translation proteins PRC-barrel domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
LysM domain LysM domain 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Zinc beta-ribbon DNA primase core 11
GroEL-intermediate domain like GroEL apical domain-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
RNase III domain-like dsRNA-binding domain-like 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
PHP14-like Phospholipase D/nuclease 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Lysozyme-like LysM domain 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Smc hinge domain Myosin rod fragments 11
Carbamate kinase-like ACT-like 11
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Homeodomain-like DNA-glycosylase 11
PurS-like PurM C-terminal domain-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) TATA-box binding protein-like 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
GAF domain-like Nucleotide cyclase 11
CarD-like TRCF domain-like 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Quinoprotein alcohol dehydrogenase-like Quinoprotein alcohol dehydrogenase-like 11
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
GroES-like ACP-like 11
PDZ domain-like ClpP/crotonase 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Adenine nucleotide alpha hydrolases-like GAF domain-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Nucleic acid-binding proteins GAD domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
Class II aaRS and biotin synthetases GAD domain-like 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Translation proteins ThrRS/AlaRS common domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Enolase C-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
Globin-like Nucleotide cyclase 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Poly A polymerase C-terminal region-like ACT-like 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
2Fe-2S ferredoxin-like ADC-like 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
PUA domain-like Nucleotidylyl transferase 11
FMN-binding split barrel UbiD C-terminal domain-like 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Dimeric alpha+beta barrel Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
C-type lectin-like S-adenosyl-L-methionine-dependent methyltransferases 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
PPK N-terminal domain-like PHP14-like 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Adhesin YadA, collagen-binding domain Adhesin YadA, collagen-binding domain 11
PheT/TilS domain Putative DNA-binding domain 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11

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