SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Photobacterium profundum SS9

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

835 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 821
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 3820
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 3715
Homeodomain-like Homeodomain-like 297
Actin-like ATPase domain Actin-like ATPase domain 217
CheY-like C-terminal effector domain of the bipartite response regulators 212
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 185
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 167
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 166
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 166
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 1512
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 152
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 143
Homodimeric domain of signal transducing histidine kinase CheY-like 1411
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 135
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 125
Homeodomain-like Ribonuclease H-like 122
CheY-like P-loop containing nucleoside triphosphate hydrolases 124
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 124
CheY-like Homeodomain-like 113
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 112
Thioredoxin-like GST C-terminal domain-like 111
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 111
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 114
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 101
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 103
P-loop containing nucleoside triphosphate hydrolases Translation proteins 107
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 107
Nucleotide cyclase EAL domain-like 104
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 103
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 103
Thiolase-like Thiolase-like 104
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 92
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 94
(Trans)glycosidases Glycosyl hydrolase domain 96
GroES-like NAD(P)-binding Rossmann-fold domains 92
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 93
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 81
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 86
Cytochrome c Cytochrome c 84
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 87
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 74
MetI-like MetI-like 73
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 76
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 71
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 71
ACT-like ACT-like 74
Alpha-L RNA-binding motif Pseudouridine synthase 72
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 76
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 76
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 71
PYP-like sensor domain (PAS domain) Nucleotide cyclase 66
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 61
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 64
Regulatory protein AraC Homeodomain-like 62
Acetyl-CoA synthetase-like ACP-like 66
E set domains (Trans)glycosidases 64
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 63
TPR-like TPR-like 64
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 65
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 61
P-loop containing nucleoside triphosphate hydrolases MOP-like 61
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 66
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 64
Translation proteins EF-G C-terminal domain-like 53
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 53
E set domains Glycosyl hydrolase domain 53
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 53
CoA-dependent acyltransferases CoA-dependent acyltransferases 55
CoA-dependent acyltransferases Acetyl-CoA synthetase-like 55
Nucleic acid-binding proteins Nucleic acid-binding proteins 54
PurM N-terminal domain-like PurM C-terminal domain-like 52
Homeodomain-like SIS domain 51
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 54
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 52
CheY-like Histidine-containing phosphotransfer domain, HPT domain 55
alpha-helical ferredoxin Nucleotide-binding domain 54
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 55
PLP-binding barrel Alanine racemase C-terminal domain-like 52
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 42
"Winged helix" DNA-binding domain PLP-dependent transferases 41
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 44
TrkA C-terminal domain-like TrkA C-terminal domain-like 42
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 42
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 44
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 42
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 43
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 42
EF-G C-terminal domain-like EF-G C-terminal domain-like 42
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 42
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 42
CheY-like PYP-like sensor domain (PAS domain) 43
HlyD-like secretion proteins HlyD-like secretion proteins 41
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 41
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 41
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 41
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 41
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 42
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 43
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
CoA-dependent acyltransferases ACP-like 44
CheY-like CheY-like 43
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 43
Phospholipase D/nuclease Phospholipase D/nuclease 43
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 43
Sensory domain-like PYP-like sensor domain (PAS domain) 43
Calcium ATPase, transduction domain A HAD-like 32
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 32
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 32
Nucleic acid-binding proteins Translation proteins SH3-like domain 32
HMA, heavy metal-associated domain HAD-like 32
Lysozyme-like beta-lactamase/transpeptidase-like 32
PYP-like sensor domain (PAS domain) EAL domain-like 33
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 32
cAMP-binding domain-like CBS-domain pair 31
CheY-like Nucleotide cyclase 32
HD-domain/PDEase-like Nucleotidyltransferase 32
Sensory domain-like Nucleotide cyclase 33
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 32
Galactose-binding domain-like (Trans)glycosidases 32
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 32
Nucleotidyltransferase ACT-like 32
Ribosomal protein S5 domain 2-like EF-G C-terminal domain-like 32
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 31
HD-domain/PDEase-like ACT-like 32
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 33
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 32
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 32
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 32
HAMP domain-like CheY-like 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 32
PreATP-grasp domain Rudiment single hybrid motif 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
Enolase N-terminal domain-like Enolase C-terminal domain-like 31
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 33
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 33
Carbohydrate binding domain (Trans)glycosidases 33
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 32
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 31
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
CheY-like TPR-like 32
Galactose-binding domain-like Galactose mutarotase-like 32
Nucleic acid-binding proteins RuvA domain 2-like 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 33
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 33
FKBP-like Triger factor/SurA peptide-binding domain-like 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 33
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 32
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 32
Phoshotransferase/anion transport protein PTS system IIB component-like 33
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 32
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 33
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 31
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 32
ACP-like ACP-like 33
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 32
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 32
"Winged helix" DNA-binding domain GAF domain-like 31
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 33
EAL domain-like HD-domain/PDEase-like 31
Single hybrid motif CoA-dependent acyltransferases 32
2Fe-2S ferredoxin-like alpha-helical ferredoxin 32
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 31
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 32
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 33
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 33
beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain 32
HAD-like Calcium ATPase, transmembrane domain M 32
RmlC-like cupins Homeodomain-like 31
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 31
beta-N-acetylhexosaminidase-like domain (Trans)glycosidases 33
P-loop containing nucleoside triphosphate hydrolases TPR-like 22
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 21
Chitinase insertion domain Carbohydrate binding domain 22
Thiolase-like NAD(P)-binding Rossmann-fold domains 22
HD-domain/PDEase-like TGS-like 21
PDZ domain-like PDZ domain-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 21
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 21
(Trans)glycosidases Chitinase insertion domain 22
Carbamate kinase-like ACT-like 22
Class II aaRS and biotin synthetases SufE/NifU 21
CheY-like Methylesterase CheB, C-terminal domain 22
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Trypsin-like serine proteases PDZ domain-like 22
cAMP-binding domain-like "Winged helix" DNA-binding domain 21
Carbohydrate-binding domain (Trans)glycosidases 22
alpha-helical ferredoxin 4Fe-4S ferredoxins 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 22
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 21
NAD(P)-binding Rossmann-fold domains S-adenosyl-L-methionine-dependent methyltransferases 22
beta-Galactosidase/glucuronidase domain Galactose mutarotase-like 21
Pentapeptide repeat-like Pentapeptide repeat-like 21
Thiolase-like FabD/lysophospholipase-like 22
Aldolase Single hybrid motif 21
(Trans)glycosidases Galactose mutarotase-like 21
PK beta-barrel domain-like PK C-terminal domain-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 21
FabD/lysophospholipase-like ACP-like 22
gamma-Crystallin-like gamma-Crystallin-like 21
Nucleotide-binding domain 4Fe-4S ferredoxins 22
Phoshotransferase/anion transport protein HPr-like 22
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 21
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
Zinc beta-ribbon Zinc beta-ribbon 22
DNA methylase specificity domain DNA methylase specificity domain 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
ACT-like P-loop containing nucleoside triphosphate hydrolases 22
CheC-like Surface presentation of antigens (SPOA) 22
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
Carbohydrate-binding domain beta-N-acetylhexosaminidase-like domain 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 21
GroES-like GroES-like 21
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 22
TGS-like ACT-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
CoA-dependent acyltransferases S-adenosyl-L-methionine-dependent methyltransferases 22
Nucleotidyltransferase TGS-like 21
Carbamate kinase-like NAD(P)-binding Rossmann-fold domains 22
Aspartate/glutamate racemase Aspartate/glutamate racemase 21
Aldolase post-HMGL domain-like 21
Cupredoxins Cytochrome c 22
CheW-like CheY-like 21
NAD(P)-binding Rossmann-fold domains ACP-like 22
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 21
ACP-like S-adenosyl-L-methionine-dependent methyltransferases 22
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 21
Translation proteins Ribosomal protein S5 domain 2-like 21
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 22
HAMP domain-like PYP-like sensor domain (PAS domain) 22
PYP-like sensor domain (PAS domain) Sporulation response regulatory protein Spo0B 21
Folate-binding domain Aminomethyltransferase beta-barrel domain 21
Protein kinase-like (PK-like) Protein kinase-like (PK-like) 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 21
Carbamate kinase-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
Periplasmic binding protein-like II Lysozyme-like 22
MalF N-terminal region-like MetI-like 22
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 22
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
P-loop containing nucleoside triphosphate hydrolases Glucocorticoid receptor-like (DNA-binding domain) 22
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 21
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 22
E set domains E set domains 22
Carbohydrate binding domain Carbohydrate binding domain 22
Sporulation response regulatory protein Spo0B ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
Actin-like ATPase domain HD-domain/PDEase-like 22
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 22
Succinyl-CoA synthetase domains Glutathione synthetase ATP-binding domain-like 22
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 21
Histidine-containing phosphotransfer domain, HPT domain CheW-like 21
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
MoeA N-terminal region -like MoeA C-terminal domain-like 22
LysM domain LysM domain 22
FliG FliG 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 21
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 21
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 21
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 21
Ribonuclease H-like DNA/RNA polymerases 22
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 21
OMPA-like OmpA-like 21
Lysozyme-like LysM domain 22
"Winged helix" DNA-binding domain C-terminal domain of arginine repressor 21
CBS-domain pair FAD-binding/transporter-associated domain-like 21
Thiolase-like ACP-like 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
Acetyl-CoA synthetase-like S-adenosyl-L-methionine-dependent methyltransferases 22
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 21
Sensory domain-like Sporulation response regulatory protein Spo0B 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 22
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 21
Riboflavin synthase domain-like Riboflavin synthase domain-like 21
ACT-like Formyltransferase 21
Nucleotide-diphospho-sugar transferases PilZ domain-like 21
"Winged helix" DNA-binding domain Actin-like ATPase domain 21
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 22
FMN-linked oxidoreductases Nucleotide-binding domain 22
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 21
Siroheme synthase middle domains-like Tetrapyrrole methylase 21
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 21
post-HMGL domain-like Single hybrid motif 21
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 22
PLP-dependent transferases PLP-dependent transferases 22
Class I glutamine amidotransferase-like Homeodomain-like 21
cAMP-binding domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Homodimeric domain of signal transducing histidine kinase CheW-like 21
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 21
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 22
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 22
gamma-Crystallin-like PLC-like phosphodiesterases 21
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 21
THUMP domain-like Adenine nucleotide alpha hydrolases-like 11
HAD-like Ribosomal protein S5 domain 2-like 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Phage tail proteins Phage fibre proteins 11
PH0987 N-terminal domain-like Cyclophilin-like 11
L domain-like Protein kinase-like (PK-like) 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
alpha-helical ferredoxin Formate dehydrogenase/DMSO reductase, domains 1-3 11
P-loop containing nucleoside triphosphate hydrolases Nudix 11
gp5 N-terminal domain-like Phage fibre proteins 11
Galactose-binding domain-like Chondroitin AC/alginate lyase 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
Starch-binding domain-like E set domains 11
Voltage-gated potassium channels Periplasmic binding protein-like II 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
NTF2-like Sec-C motif 11
DNA primase core DNA primase DnaG, C-terminal domain 11
2Fe-2S ferredoxin-like ADC-like 11
Homeodomain-like TATA-box binding protein-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
PTS system fructose IIA component-like Phosphohistidine domain 11
Chorismate mutase II Periplasmic binding protein-like II 11
Aldolase AFP III-like domain 11
PIN domain-like DNA/RNA polymerases 11
Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain 11
Porins Porins 11
Protease propeptides/inhibitors Subtilisin-like 11
TGS-like Class II aaRS and biotin synthetases 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
HIT-like HIT-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Phoshotransferase/anion transport protein Phoshotransferase/anion transport protein 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Origin of replication-binding domain, RBD-like P-loop containing nucleoside triphosphate hydrolases 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Phosphotyrosine protein phosphatases I "Winged helix" DNA-binding domain 11
Galactose mutarotase-like Six-hairpin glycosidases 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase S-adenosyl-L-methionine-dependent methyltransferases 11
Chorismate mutase II 6-phosphogluconate dehydrogenase C-terminal domain-like 11
Chorismate mutase II NAD(P)-binding Rossmann-fold domains 11
Ribonuclease H-like Nucleic acid-binding proteins 11
MFS general substrate transporter MFS general substrate transporter 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
FabD/lysophospholipase-like CoA-dependent acyltransferases 11
Chondroitin AC/alginate lyase Galactose mutarotase-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Ribonuclease H-like HRDC-like 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
C-type lectin-like S-adenosyl-L-methionine-dependent methyltransferases 11
Acid proteases Acid proteases 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
ALDH-like Dehydroquinate synthase-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Cupredoxins Cupredoxins 11
HPr-like Phosphoenolpyruvate/pyruvate domain 11
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 11
HAMP domain-like Nucleotide cyclase 11
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
PilZ domain-like PilZ domain-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
Globin-like Riboflavin synthase domain-like 11
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Carbohydrate-binding domain E set domains 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
PreATP-grasp domain Methylglyoxal synthase-like 11
HPr-like Phosphohistidine domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 11
Isochorismatase-like hydrolases ACP-like 11
TPR-like Nucleotide cyclase 11
RuvA domain 2-like BRCT domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Homeodomain-like NagB/RpiA/CoA transferase-like 11
FAD/NAD(P)-binding domain Thioredoxin-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Thiolase-like CoA-dependent acyltransferases 11
PPK N-terminal domain-like PHP14-like 11
CBD9-like Homodimeric domain of signal transducing histidine kinase 11
CheY-like cAMP-binding domain-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
4Fe-4S ferredoxins Radical SAM enzymes 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
Putative DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
Thiolase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
CO dehydrogenase ISP C-domain like CO dehydrogenase molybdoprotein N-domain-like 11
HesB-like domain Fe-S cluster assembly (FSCA) domain-like 11
FAD/NAD(P)-binding domain Rhodanese/Cell cycle control phosphatase 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
FAD/NAD-linked reductases, dimerisation (C-terminal) domain Rhodanese/Cell cycle control phosphatase 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Galactose-binding domain-like Hyaluronate lyase-like, C-terminal domain 11
Tex N-terminal region-like RuvA domain 2-like 11
Nucleic acid-binding proteins PheT/TilS domain 11
Thioredoxin-like Six-hairpin glycosidases 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
P-loop containing nucleoside triphosphate hydrolases C-terminal effector domain of the bipartite response regulators 11
Trigger factor ribosome-binding domain FKBP-like 11
Macro domain-like Zn-dependent exopeptidases 11
Zn-dependent exopeptidases Fibronectin type III 11
Lysozyme-like L,D-transpeptidase catalytic domain-like 11
MOSC N-terminal domain-like Riboflavin synthase domain-like 11
Nucleotide-binding domain Formate dehydrogenase/DMSO reductase, domains 1-3 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
UDP-Glycosyltransferase/glycogen phosphorylase Acyl-CoA N-acyltransferases (Nat) 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Periplasmic binding protein-like II GlnB-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
MOSC N-terminal domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Flavoproteins Rubredoxin-like 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Acyl-CoA N-acyltransferases (Nat) 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
4Fe-4S ferredoxins ADC-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
"Winged helix" DNA-binding domain MOP-like 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Nitrous oxide reductase, N-terminal domain Cupredoxins 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
Flavoproteins Riboflavin synthase domain-like 11
P-loop containing nucleoside triphosphate hydrolases Zn-binding ribosomal proteins 11
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 11
Ribosomal protein L6 Ribosomal protein L6 11
Ribbon-helix-helix Replication modulator SeqA, C-terminal DNA-binding domain 11
GAF domain-like Homeodomain-like 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
CheY-like EAL domain-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
TGS-like ThrRS/AlaRS common domain 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
RmlC-like cupins RmlC-like cupins 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidyltransferase Nucleotidyltransferase 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
beta-Roll Carbohydrate binding domain 11
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
CBS-domain pair MgtE membrane domain-like 11
CheY-like CheC-like 11
HlyD-like secretion proteins Outer membrane efflux proteins (OEP) 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
PTS system fructose IIA component-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Starch-binding domain-like (Trans)glycosidases 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
MOP-like MOP-like 11
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 11
CBD9-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Sporulation related repeat C-type lectin-like 11
Subtilisin-like Galactose-binding domain-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase CoA-dependent acyltransferases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
Translation proteins ThrRS/AlaRS common domain 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
PTS system fructose IIA component-like HPr-like 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Protease propeptides/inhibitors Galactose-binding domain-like 11
Thioredoxin-like TPR-like 11
cAMP-binding domain-like Homodimeric domain of signal transducing histidine kinase 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
PIN domain-like Ribonuclease H-like 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
ADC-like Cytochrome c 11
Ribonuclease H-like RuvA domain 2-like 11
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Metallo-hydrolase/oxidoreductase Flavoproteins 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
MOSC N-terminal domain-like 2Fe-2S ferredoxin-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
ACT-like Homeodomain-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
NTF2-like NTF2-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 11
FabD/lysophospholipase-like Acetyl-CoA synthetase-like 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Sensory domain-like Sensory domain-like 11
PK beta-barrel domain-like 2Fe-2S ferredoxin-like 11
L9 N-domain-like Ribonuclease H-like 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
TPR-like C-terminal effector domain of the bipartite response regulators 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
DeoB insert domain-like Alkaline phosphatase-like 11
Radical SAM enzymes Radical SAM enzymes 11
Translation proteins Translation proteins 11
Acetyl-CoA synthetase-like Glycerol-3-phosphate (1)-acyltransferase 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
PYP-like sensor domain (PAS domain) Homeodomain-like 11
Ribonuclease H-like Transposase IS200-like 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
vWA-like TPR-like 11
L30e-like alpha/beta knot 11
Homeodomain-like DNA-glycosylase 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Ribokinase-like Nucleotidylyl transferase 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
TK C-terminal domain-like 4Fe-4S ferredoxins 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains Acetyl-CoA synthetase-like 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 4Fe-4S ferredoxins 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
UbiD C-terminal domain-like UbiD C-terminal domain-like 11
Phage tail proteins Phage tail proteins 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
GAF domain-like Phosphohistidine domain 11
TPR-like HCP-like 11
PurS-like FGAM synthase PurL, linker domain 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Thiolase-like Thioesterase/thiol ester dehydrase-isomerase 11
CRISPR-associated protein CRISPR-associated protein 11
L-aspartase-like Acyl-CoA N-acyltransferases (Nat) 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
RNase III domain-like dsRNA-binding domain-like 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Bet v1-like 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Nudix Acid phosphatase/Vanadium-dependent haloperoxidase 11
Formyltransferase FMT C-terminal domain-like 11
Cytidine deaminase-like Cytidine deaminase-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Nucleic acid-binding proteins BRCT domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Adenine nucleotide alpha hydrolases-like Rhodanese/Cell cycle control phosphatase 11
ACP-like alpha/beta-Hydrolases 11
GroEL equatorial domain-like GroEL equatorial domain-like 11
E set domains Six-hairpin glycosidases 11
Nucleic acid-binding proteins GAD domain-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Chaperone J-domain HSP40/DnaJ peptide-binding domain 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
P-loop containing nucleoside triphosphate hydrolases Molybdenum cofactor biosynthesis proteins 11
Nucleotide-binding domain ADC-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Molybdenum cofactor biosynthesis proteins CinA-like 11
Caspase-like PKD domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
DNA clamp DNA clamp 11
FKBP-like FKBP-like 11
Lysozyme-like Carbohydrate binding domain 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Multiheme cytochromes Multiheme cytochromes 11
FabD/lysophospholipase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Barwin-like endoglucanases Sporulation related repeat 11
Subtilisin-like Carbohydrate binding domain 11
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 11
PP2C-like Protein kinase-like (PK-like) 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Acetyl-CoA synthetase-like alpha/beta-Hydrolases 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Starch-binding domain-like Glycosyl hydrolase domain 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
alpha/beta-Hydrolases alpha/beta-Hydrolases 11
GIY-YIG endonuclease RuvA domain 2-like 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Nitrous oxide reductase, N-terminal domain Multiheme cytochromes 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Tricorn protease domain 2 MetI-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
FMN-linked oxidoreductases 4Fe-4S ferredoxins 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) DNA-glycosylase 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
beta-Roll beta-Roll 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Nucleotidylyl transferase tRNA-binding arm 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase Acetyl-CoA synthetase-like 11
Galactose mutarotase-like Hyaluronate lyase-like, C-terminal domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 11
MgtE N-terminal domain-like CBS-domain pair 11
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 11
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
PUA domain-like alpha/beta knot 11
P-loop containing nucleoside triphosphate hydrolases MoeA C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Tex N-terminal region-like Ribonuclease H-like 11
PurS-like PurM N-terminal domain-like 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
C-type lectin-like Aerolisin/ETX pore-forming domain 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
MOSC N-terminal domain-like PK beta-barrel domain-like 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Thiamin diphosphate-binding fold (THDP-binding) 4Fe-4S ferredoxins 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Pili subunits GspK insert domain-like 11
PGBD-like L,D-transpeptidase catalytic domain-like 11
FAD-linked oxidoreductase ALDH-like 11
Acyl-CoA N-acyltransferases (Nat) Thioesterase/thiol ester dehydrase-isomerase 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
HisI-like all-alpha NTP pyrophosphatases 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
H-NS histone-like proteins H-NS histone-like proteins 11
Putative DNA-binding domain Translation proteins 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Cytochrome c 11
UROD/MetE-like UROD/MetE-like 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
PHP14-like Phospholipase D/nuclease 11
Sensory domain-like EAL domain-like 11
ClpP/crotonase NfeD domain-like 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Nqo1 FMN-binding domain-like alpha-helical ferredoxin 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
Chorismate mutase II ACT-like 11
HRDC-like HRDC-like 11
Galactose-binding domain-like Galactose-binding domain-like 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Metalloproteases ("zincins"), catalytic domain Galactose-binding domain-like 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
PurS-like Class I glutamine amidotransferase-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Phage tail proteins gp5 N-terminal domain-like 11
FMN-binding split barrel UbiD C-terminal domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
"Winged helix" DNA-binding domain MukF C-terminal domain-like 11
Zn-dependent exopeptidases LysM domain 11
ACP-like Glycerol-3-phosphate (1)-acyltransferase 11
2Fe-2S ferredoxin-like Nucleotide-binding domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
PTS system IIB component-like PTS system IIB component-like 11
Carbamate kinase-like PUA domain-like 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 11
PreATP-grasp domain PreATP-grasp domain 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
P-loop containing nucleoside triphosphate hydrolases Acyl-CoA N-acyltransferases (Nat) 11
Acyl-CoA N-acyltransferases (Nat) Nucleotidylyl transferase 11
PK beta-barrel domain-like Riboflavin synthase domain-like 11
"Winged helix" DNA-binding domain C-terminal domain of transcriptional repressors 11
TATA-box binding protein-like DNA-glycosylase 11
Metallo-hydrolase/oxidoreductase Rubredoxin-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
RuvA domain 2-like RuvA domain 2-like 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
DNA-glycosylase Nudix 11
PheT/TilS domain Putative DNA-binding domain 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Hsp33 domain HSP33 redox switch-like 11
ABC transporter involved in vitamin B12 uptake, BtuC ABC transporter involved in vitamin B12 uptake, BtuC 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
FAS1 domain FAS1 domain 11
lambda repressor-like DNA-binding domains RmlC-like cupins 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
ACT-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
YjgF-like YjgF-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
YjeF N-terminal domain-like Ribokinase-like 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
P-loop containing nucleoside triphosphate hydrolases MoeA N-terminal region -like 11
Tetrahydrobiopterin biosynthesis enzymes-like Tetrahydrobiopterin biosynthesis enzymes-like 11
alpha-helical ferredoxin ADC-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
LysM domain L,D-transpeptidase catalytic domain-like 11
Translation proteins "Winged helix" DNA-binding domain 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
CarD-like TRCF domain-like 11
beta-N-acetylhexosaminidase-like domain E set domains 11
LeuD/IlvD-like Aconitase iron-sulfur domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Translation proteins PRC-barrel domain 11
CO dehydrogenase ISP C-domain like Molybdenum cofactor-binding domain 11
PK beta-barrel domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
YbiA-like RibA-like 11
Nudix Nudix 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Thiolase-like Acetyl-CoA synthetase-like 11
Zinc beta-ribbon DNA primase core 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
THUMP domain-like Rhodanese/Cell cycle control phosphatase 11
Multiheme cytochromes Cytochrome c 11
FMN-linked oxidoreductases alpha-helical ferredoxin 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) TATA-box binding protein-like 11
CBS-domain pair CBS-domain pair 11
YajQ-like YajQ-like 11
Ribulose-phoshate binding barrel Ribulose-phoshate binding barrel 11
ClpP/crotonase ClpP/crotonase 11
PHP domain-like Nucleic acid-binding proteins 11
NAD(P)-binding Rossmann-fold domains CoA-dependent acyltransferases 11
GAF domain-like Nucleotide cyclase 11
alpha-helical ferredoxin alpha-helical ferredoxin 11
GspK insert domain-like GspK insert domain-like 11
"Winged helix" DNA-binding domain Chorismate lyase-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Methionine synthase domain Methionine synthase activation domain-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Chondroitin AC/alginate lyase Hyaluronate lyase-like, C-terminal domain 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
P-loop containing nucleoside triphosphate hydrolases PGBD-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
PDZ domain-like ClpP/crotonase 11
Periplasmic binding protein-like II ACT-like 11
TerB-like Chaperone J-domain 11
Pseudouridine synthase PUA domain-like 11
PTS system fructose IIA component-like Phosphoenolpyruvate/pyruvate domain 11
Single hybrid motif Single hybrid motif 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Glycoside hydrolase/deacetylase Carbohydrate binding domain 11
PurS-like PurM C-terminal domain-like 11
Periplasmic binding protein-like I Homeodomain-like 11
YrdC/RibB RibA-like 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Bacterial muramidases Lysozyme-like 11
Metallo-hydrolase/oxidoreductase SCP-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11

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