SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Sulfuricurvum kujiense DSM 16994

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


Add or remove domain pairs

The links below permit the addition or removal of specific sets of domain combination pairs.


Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Add or remove genomes

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Add or remove genomes:
Include genomes:
Exclude genomes:


Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

566 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 4621
Nucleotide cyclase EAL domain-like 3015
PYP-like sensor domain (PAS domain) Nucleotide cyclase 2719
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 2119
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 199
CheY-like C-terminal effector domain of the bipartite response regulators 121
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 1110
PYP-like sensor domain (PAS domain) EAL domain-like 118
Homodimeric domain of signal transducing histidine kinase CheY-like 109
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1010
CheY-like PYP-like sensor domain (PAS domain) 97
CheY-like Nucleotide cyclase 95
Actin-like ATPase domain Actin-like ATPase domain 94
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 99
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 86
Periplasmic binding protein-like II Nucleotide cyclase 86
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 73
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 73
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 73
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 73
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 64
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 62
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 62
GAF domain-like Nucleotide cyclase 66
CheY-like CheY-like 64
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 62
Cytochrome c Cytochrome c 63
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 65
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 65
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
PYP-like sensor domain (PAS domain) HD-domain/PDEase-like 54
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 52
CheY-like HD-domain/PDEase-like 54
CheY-like Histidine-containing phosphotransfer domain, HPT domain 55
PreATP-grasp domain Rudiment single hybrid motif 53
EAL domain-like HD-domain/PDEase-like 51
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 53
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 52
P-loop containing nucleoside triphosphate hydrolases Translation proteins 55
Ribosomal protein S5 domain 2-like P-loop containing nucleoside triphosphate hydrolases 55
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 53
Sensory domain-like Nucleotide cyclase 54
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 43
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 42
GAF domain-like PYP-like sensor domain (PAS domain) 44
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 41
CBS-domain pair Nucleotide cyclase 44
Calcium ATPase, transduction domain A HAD-like 43
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 41
cAMP-binding domain-like "Winged helix" DNA-binding domain 41
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 41
PurM N-terminal domain-like PurM C-terminal domain-like 42
CheW-like CheY-like 43
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 43
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 42
PLP-binding barrel Alanine racemase C-terminal domain-like 42
HAD-like Calcium ATPase, transmembrane domain M 43
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 42
GAF domain-like EAL domain-like 44
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 41
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 41
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 43
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 43
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 33
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 31
ParB/Sulfiredoxin KorB DNA-binding domain-like 31
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 31
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 32
RuvA domain 2-like Nucleic acid-binding proteins 33
CheY-like EAL domain-like 31
DNA methylase specificity domain DNA methylase specificity domain 32
FKBP-like Triger factor/SurA peptide-binding domain-like 32
Periplasmic binding protein-like II Periplasmic binding protein-like II 32
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Alpha-L RNA-binding motif Pseudouridine synthase 31
Histidine-containing phosphotransfer domain, HPT domain CheW-like 32
Resolvase-like Homeodomain-like 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
Homodimeric domain of signal transducing histidine kinase CheW-like 32
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 32
FAD/NAD(P)-binding domain HI0933 insert domain-like 31
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 31
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Aldolase post-HMGL domain-like 33
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 32
P-loop containing nucleoside triphosphate hydrolases GAF domain-like 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 32
L30e-like alpha/beta knot 21
Protein kinase-like (PK-like) GAF domain-like 22
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 21
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 22
Phospholipase D/nuclease Phospholipase D/nuclease 22
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 22
P-loop containing nucleoside triphosphate hydrolases TrpR-like 21
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 21
GAF domain-like Homodimeric domain of signal transducing histidine kinase 22
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 21
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 21
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
NAD(P)-binding Rossmann-fold domains ACT-like 22
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
FliG FliG 21
TT1751-like TT1751-like 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
HD-domain/PDEase-like HD-domain/PDEase-like 22
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 21
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 22
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 22
Aldolase AFP III-like domain 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 22
CheC-like Surface presentation of antigens (SPOA) 22
HD-domain/PDEase-like Nucleotide cyclase 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 21
ACT-like ACT-like 22
CheY-like Methylesterase CheB, C-terminal domain 21
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 21
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
Nucleotide-diphospho-sugar transferases Phosphoglucomutase, C-terminal domain 22
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 21
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 22
Phase 1 flagellin Phase 1 flagellin 21
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
MOP-like MOP-like 22
Periplasmic binding protein-like II PYP-like sensor domain (PAS domain) 22
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
Nucleic acid-binding proteins Nucleic acid-binding proteins 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 22
2Fe-2S ferredoxin-like alpha-helical ferredoxin 22
Sensory domain-like EAL domain-like 22
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 22
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 22
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 21
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 21
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 22
TPR-like TPR-like 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
Nucleotide-diphospho-sugar transferases Phosphoglucomutase, first 3 domains 22
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 21
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
4Fe-4S ferredoxins 4Fe-4S ferredoxins 21
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 21
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 22
CBS-domain pair CBS-domain pair 22
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 21
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
MoeA N-terminal region -like MoeA C-terminal domain-like 21
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 21
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
HD-domain/PDEase-like Nucleotidyltransferase 22
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 21
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 22
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
alpha-helical ferredoxin Nucleotide-binding domain 22
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 21
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 21
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 21
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
FMN-dependent nitroreductase-like FMN-dependent nitroreductase-like 21
GAF domain-like HD-domain/PDEase-like 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
EAL domain-like CBS-domain pair 22
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 21
Oxidoreductase molybdopterin-binding domain E set domains 22
Sensory domain-like PYP-like sensor domain (PAS domain) 22
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 21
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 22
SufE/NifU Fe-S cluster assembly (FSCA) domain-like 22
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 21
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 21
Translation proteins EF-G C-terminal domain-like 22
GroEL equatorial domain-like GroEL apical domain-like 11
Outer membrane efflux proteins (OEP) HCP-like 11
PHP14-like Phospholipase D/nuclease 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
TK C-terminal domain-like 4Fe-4S ferredoxins 11
Class II aaRS and biotin synthetases GAD domain-like 11
UbiD C-terminal domain-like UbiD C-terminal domain-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
P-loop containing nucleoside triphosphate hydrolases Nucleotide cyclase 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
GroEL-intermediate domain like GroEL apical domain-like 11
Cyclophilin-like Cyclophilin-like 11
Thiolase-like Thiolase-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Actin-like ATPase domain HD-domain/PDEase-like 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
TSP type-3 repeat Concanavalin A-like lectins/glucanases 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Ribonuclease H-like RuvA domain 2-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
RuvA domain 2-like BRCT domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Periplasmic binding protein-like II GAF domain-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Methylated DNA-protein cysteine methyltransferase, C-terminal domain Acyl-CoA N-acyltransferases (Nat) 11
TPR-like EAL domain-like 11
Metallo-hydrolase/oxidoreductase HD-domain/PDEase-like 11
SpoIIaa-like cAMP-binding domain-like 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Protein kinase-like (PK-like) PYP-like sensor domain (PAS domain) 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
PPK N-terminal domain-like PHP14-like 11
Radical SAM enzymes Nitrogenase accessory factor-like 11
Lysozyme-like LysM domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Metallo-hydrolase/oxidoreductase GAF domain-like 11
YajQ-like YajQ-like 11
HCP-like Fe-S cluster assembly (FSCA) domain-like 11
HD-domain/PDEase-like ACT-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
cAMP-binding domain-like CBS-domain pair 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Nucleic acid-binding proteins GAD domain-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
Translation proteins ThrRS/AlaRS common domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Protein kinase-like (PK-like) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
DNA clamp DNA clamp 11
Rubredoxin-like Ferritin-like 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Barwin-like endoglucanases Sporulation related repeat 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Fibronectin type III Fibronectin type III 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
PreATP-grasp domain Methylglyoxal synthase-like 11
CarD-like TRCF domain-like 11
TTHA1013/TTHA0281-like Fe-S cluster assembly (FSCA) domain-like 11
NTF2-like NTF2-like 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Thiamin diphosphate-binding fold (THDP-binding) 4Fe-4S ferredoxins 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Trigger factor ribosome-binding domain FKBP-like 11
NAD(P)-binding Rossmann-fold domains Citrate synthase 11
Nucleotidylyl transferase tRNA-binding arm 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
YrdC/RibB Actin-like ATPase domain 11
Metallo-hydrolase/oxidoreductase Flavoproteins 11
PDZ domain-like ClpP/crotonase 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Rad50 coiled-coil Zn hook 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Ribonuclease H-like Nucleic acid-binding proteins 11
HCP-like Outer membrane phospholipase A (OMPLA) 11
TTHA1013/TTHA0281-like HCP-like 11
Voltage-gated potassium channels TrkA C-terminal domain-like 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Chorismate mutase II Periplasmic binding protein-like II 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
L domain-like Protein kinase-like (PK-like) 11
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Methylated DNA-protein cysteine methyltransferase domain Acyl-CoA N-acyltransferases (Nat) 11
Periplasmic binding protein-like II ACT-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Aldolase S-adenosyl-L-methionine-dependent methyltransferases 11
FAD/NAD(P)-binding domain HydA/Nqo6-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Glycerol-3-phosphate (1)-acyltransferase Acyl-CoA N-acyltransferases (Nat) 11
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 11
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
TPR-like Nucleotide cyclase 11
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Homeodomain-like Homeodomain-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
ACT-like Formyltransferase 11
E set domains Glycosyl hydrolase domain 11
(Trans)glycosidases Glycosyl hydrolase domain 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
OMPA-like TSP type-3 repeat 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Protein kinase-like (PK-like) TPR-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Cyclophilin-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
post-HMGL domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Ribosomal protein L6 Ribosomal protein L6 11
S-adenosyl-L-methionine-dependent methyltransferases DNA methylase specificity domain 11
Rudiment single hybrid motif Cyclophilin-like 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
RuvA domain 2-like RuvA domain 2-like 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
PreATP-grasp domain PH0987 N-terminal domain-like 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
PIN domain-like Ribonuclease H-like 11
Porins Porins 11
Periplasmic binding protein-like II HD-domain/PDEase-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
PIN domain-like DNA/RNA polymerases 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
CBS-domain pair PYP-like sensor domain (PAS domain) 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
HIT-like HIT-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Nitrogenase accessory factor-like 11
Ferredoxin thioredoxin reductase (FTR), catalytic beta chain Rhodanese/Cell cycle control phosphatase 11
Chorismate mutase II ACT-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
beta-Roll beta-Roll 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 11
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Glycoside hydrolase/deacetylase Galactose mutarotase-like 11
Thioredoxin-like Six-hairpin glycosidases 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 11
Cyclophilin-like Single hybrid motif 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
HisI-like all-alpha NTP pyrophosphatases 11
Trimeric LpxA-like enzymes Trimeric LpxA-like enzymes 11
Cupredoxins Cupredoxins 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Nucleotidylyl transferase GatB/YqeY motif 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
DNA-glycosylase Nudix 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Nucleotidylyl transferase Riboflavin kinase-like 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
beta-Roll Concanavalin A-like lectins/glucanases 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
post-HMGL domain-like Single hybrid motif 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 11
GAF domain-like Homeodomain-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Translation proteins Translation proteins 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
PreATP-grasp domain Single hybrid motif 11
TSP type-3 repeat beta-Roll 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
OMPA-like OmpA-like 11
Macro domain-like Zn-dependent exopeptidases 11
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
Class II aaRS and biotin synthetases Translation proteins 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
HAMP domain-like HD-domain/PDEase-like 11
Protein kinase-like (PK-like) Homodimeric domain of signal transducing histidine kinase 11
Translation proteins PRC-barrel domain 11
P-loop containing nucleoside triphosphate hydrolases PYP-like sensor domain (PAS domain) 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Rudiment single hybrid motif Single hybrid motif 11
RNase III domain-like dsRNA-binding domain-like 11
PH0987 N-terminal domain-like Single hybrid motif 11
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 11
Ribokinase-like Nucleotidylyl transferase 11
P-loop containing nucleoside triphosphate hydrolases TPR-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Homeodomain-like Acyl-CoA N-acyltransferases (Nat) 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
C-terminal effector domain of the bipartite response regulators PYP-like sensor domain (PAS domain) 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
P-loop containing nucleoside triphosphate hydrolases Homodimeric domain of signal transducing histidine kinase 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
HMA, heavy metal-associated domain HAD-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
PUA domain-like Nucleotidylyl transferase 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
CheY-like P-loop containing nucleoside triphosphate hydrolases 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
PDZ domain-like PDZ domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Protein kinase-like (PK-like) Nucleotide cyclase 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Protein kinase-like (PK-like) EAL domain-like 11
Carbamate kinase-like ACT-like 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
Sec-C motif NTF2-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Formyltransferase FMT C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Zinc beta-ribbon Zinc beta-ribbon 11
YrdC/RibB RibA-like 11
Serine metabolism enzymes domain ACT-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
PHP domain-like AF1531-like 11
Trimeric LpxA-like enzymes Phosphoglucomutase, first 3 domains 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
"Winged helix" DNA-binding domain MOP-like 11
UROD/MetE-like UROD/MetE-like 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
YjeF N-terminal domain-like Ribokinase-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Methionine synthase domain Methionine synthase activation domain-like 11
Trypsin-like serine proteases CalX-like 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
LeuD/IlvD-like Aconitase iron-sulfur domain 11
Nucleic acid-binding proteins BRCT domain 11
OMPA-like OMPA-like 11
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 11
Glutathione synthetase ATP-binding domain-like PH0987 N-terminal domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
Acylphosphatase/BLUF domain-like Actin-like ATPase domain 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
Zinc beta-ribbon DNA primase core 11
Nqo1C-terminal domain-like Nucleotide-binding domain 11
Trypsin-like serine proteases Type III secretory system chaperone-like 11
Rudiment single hybrid motif PH0987 N-terminal domain-like 11
Nucleotide-binding domain Nucleotide-binding domain 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Ribonuclease H-like DNA/RNA polymerases 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Nucleotidyltransferase TGS-like 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
vWA-like TPR-like 11
Nucleotidyltransferase ACT-like 11
PreATP-grasp domain PreATP-grasp domain 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
L,D-transpeptidase catalytic domain-like NTF2-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
PreATP-grasp domain Cyclophilin-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Trimeric LpxA-like enzymes Phosphoglucomutase, C-terminal domain 11
Homocysteine S-methyltransferase Methionine synthase domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein L25-like GatB/YqeY motif 11
Trypsin-like serine proteases PDZ domain-like 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
Nqo1C-terminal domain-like alpha-helical ferredoxin 11
P-loop containing nucleoside triphosphate hydrolases EAL domain-like 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
Aldolase Single hybrid motif 11
Homeodomain-like Probable bacterial effector-binding domain 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 4Fe-4S ferredoxins 11
TSP type-3 repeat OmpA-like 11
Tex N-terminal region-like Ribonuclease H-like 11
HD-domain/PDEase-like TGS-like 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Cyclophilin-like PH0987 N-terminal domain-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Rubredoxin-like Rubredoxin-like 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
PK beta-barrel domain-like PK C-terminal domain-like 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Tex N-terminal region-like RuvA domain 2-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
E set domains (Trans)glycosidases 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
PP2C-like Protein kinase-like (PK-like) 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
TPR-like GAF domain-like 11
FMN-binding split barrel UbiD C-terminal domain-like 11

Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes · Domain combination pairs ]