SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Cryptosporidium parvum Iowa II

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

527 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 5230
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 2214
RNA-binding domain, RBD RNA-binding domain, RBD 1810
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 179
Actin-like ATPase domain Actin-like ATPase domain 165
ABC transporter transmembrane region ABC transporter transmembrane region 157
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 137
Calcium ATPase, transduction domain A HAD-like 126
HAD-like Calcium ATPase, transmembrane domain M 126
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 104
TPR-like TPR-like 107
Ypt/Rab-GAP domain of gyp1p Ypt/Rab-GAP domain of gyp1p 105
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 104
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 104
Protein kinase-like (PK-like) EF-hand 107
ARM repeat ARM repeat 97
GroEL-intermediate domain like GroEL apical domain-like 92
GroEL equatorial domain-like GroEL-intermediate domain like 92
GroEL equatorial domain-like GroEL apical domain-like 92
TSP-1 type 1 repeat TSP-1 type 1 repeat 87
P-loop containing nucleoside triphosphate hydrolases Translation proteins 75
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 61
WD40 repeat-like WD40 repeat-like 65
FYVE/PHD zinc finger FYVE/PHD zinc finger 65
Thioredoxin-like Thioredoxin-like 66
Homeodomain-like Homeodomain-like 55
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 53
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 53
Nucleic acid-binding proteins Nucleic acid-binding proteins 55
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 52
CRAL/TRIO N-terminal domain CRAL/TRIO domain 55
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 55
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 53
Ubiquitin-like UBA-like 54
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 43
Class II aaRS and biotin synthetases Class II aaRS ABD-related 44
Cullin repeat-like Cullin homology domain 43
ARM repeat Protein kinase-like (PK-like) 44
Nucleotide-diphospho-sugar transferases Ricin B-like lectins 43
Cyclin-like Cyclin-like 44
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 42
Chaperone J-domain HSP40/DnaJ peptide-binding domain 43
beta-sandwich domain of Sec23/24 Zn-finger domain of Sec23/24 33
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 31
SNARE-like Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor 32
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 33
Cullin repeat-like "Winged helix" DNA-binding domain 32
Cullin homology domain "Winged helix" DNA-binding domain 32
C2 domain (Calcium/lipid-binding domain, CaLB) C2 domain (Calcium/lipid-binding domain, CaLB) 32
beta-sandwich domain of Sec23/24 Helical domain of Sec23/24 33
F1F0 ATP synthase subunit C F1F0 ATP synthase subunit C 31
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 31
Nucleotidyltransferase PAP/OAS1 substrate-binding domain 33
beta-sandwich domain of Sec23/24 vWA-like 33
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 32
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 32
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 32
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 32
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 32
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 33
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 32
TSP-1 type 1 repeat EGF/Laminin 32
Helical domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 33
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 33
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 33
CCCH zinc finger CCCH zinc finger 32
Sec63 N-terminal domain-like E set domains 33
cAMP-binding domain-like cAMP-binding domain-like 33
EF-hand EF-hand 33
Flavoproteins Riboflavin synthase domain-like 33
Zn-finger domain of Sec23/24 Helical domain of Sec23/24 33
vWA-like C-terminal, gelsolin-like domain of Sec23/24 33
RCC1/BLIP-II RCC1/BLIP-II 33
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 32
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 32
Growth factor receptor domain Growth factor receptor domain 33
beta-sandwich domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 33
Zn-finger domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 33
Ribonuclease H-like DNA/RNA polymerases 33
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 31
P-loop containing nucleoside triphosphate hydrolases TGS-like 31
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 32
RING/U-box SMAD/FHA domain 33
SNARE-like SNARE fusion complex 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 32
EGF/Laminin EGF/Laminin 33
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 32
Translation proteins EF-G C-terminal domain-like 33
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 32
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 33
Translation proteins Ribosomal protein S5 domain 2-like 33
Zn-finger domain of Sec23/24 vWA-like 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 33
vWA-like Helical domain of Sec23/24 33
GroES-like NAD(P)-binding Rossmann-fold domains 33
Nucleotide cyclase Nucleotide cyclase 22
UBC-like Protein kinase-like (PK-like) 21
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 21
Ricin B-like lectins LCCL domain 21
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
Acetyl-CoA synthetase-like Thiolase-like 22
UBA-like PUG domain-like 22
Ubiquitin-like Ubiquitin-like 22
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Protein kinase-like (PK-like) 22
DHS-like NAD/FAD-binding domain NAD(P)-binding Rossmann-fold domains 21
Acetyl-CoA synthetase-like FabD/lysophospholipase-like 22
Restriction endonuclease-like RuvA domain 2-like 21
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 22
ACP-like ACP-like 22
Thiolase-like NAD(P)-binding Rossmann-fold domains 22
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
FabD/lysophospholipase-like FabD/lysophospholipase-like 22
Eukaryotic type KH-domain (KH-domain type I) Eukaryotic type KH-domain (KH-domain type I) 22
Ubiquitin-like Zn-binding ribosomal proteins 21
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 22
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 22
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 22
Acetyl-CoA synthetase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
SAM/Pointed domain Protein kinase-like (PK-like) 22
HCP-like HCP-like 22
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 22
P-loop containing nucleoside triphosphate hydrolases Sec63 N-terminal domain-like 22
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 22
FYVE/PHD zinc finger SET domain 22
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 22
Galactose-binding domain-like Fibrinogen C-terminal domain-like 21
Glycerol-3-phosphate (1)-acyltransferase Glycerol-3-phosphate (1)-acyltransferase 22
Phosphofructokinase Phosphofructokinase 21
ADC-like P-loop containing nucleoside triphosphate hydrolases 22
Ricin B-like lectins Fibrinogen C-terminal domain-like 21
ACP-like FabD/lysophospholipase-like 22
ACP-like Thiolase-like 22
Chromo domain-like Acyl-CoA N-acyltransferases (Nat) 21
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 22
Fibrinogen C-terminal domain-like LCCL domain 21
Dipeptidyl peptidase I (cathepsin C), exclusion domain Cysteine proteinases 22
ACP-like GroES-like 22
Chromo domain-like Chromo domain-like 22
Acetyl-CoA synthetase-like GroES-like 22
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 22
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 21
Galactose-binding domain-like LCCL domain 21
ARM repeat Clathrin adaptor appendage domain 22
RING/U-box Cysteine proteinases 22
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 22
Chromo domain-like P-loop containing nucleoside triphosphate hydrolases 22
Phospholipase D/nuclease Phospholipase D/nuclease 21
Thiolase-like FabD/lysophospholipase-like 22
Thiolase-like GroES-like 22
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 22
Nucleotidylyl transferase Ribosomal protein L25-like 22
POZ domain Kelch motif 22
Ricin B-like lectins Galactose-binding domain-like 21
(Trans)glycosidases Glycosyl hydrolase domain 22
Chaperone J-domain Thioredoxin-like 22
HAD-like BRCT domain 21
Rad51 N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 21
Translation initiation factor 2 beta, aIF2beta, N-terminal domain Zinc-binding domain of translation initiation factor 2 beta 22
P-loop containing nucleoside triphosphate hydrolases RCC1/BLIP-II 22
(Trans)glycosidases E set domains 22
P-loop containing nucleoside triphosphate hydrolases RING/U-box 22
Acetyl-CoA synthetase-like NAD(P)-binding Rossmann-fold domains 22
DHS-like NAD/FAD-binding domain Formate/glycerate dehydrogenase catalytic domain-like 21
"Winged helix" DNA-binding domain Sec63 N-terminal domain-like 22
Thiolase-like Thiolase-like 22
Creatinase/aminopeptidase "Winged helix" DNA-binding domain 22
Growth factor receptor domain EGF/Laminin 22
Acetyl-CoA synthetase-like ACP-like 22
Kazal-type serine protease inhibitors Kazal-type serine protease inhibitors 22
ACP-like NAD(P)-binding Rossmann-fold domains 22
Kelch motif Kelch motif 22
TATA-box binding protein-like TATA-box binding protein-like 22
GroES-like GroES-like 22
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Bromodomain P-loop containing nucleoside triphosphate hydrolases 22
ACP-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
FabD/lysophospholipase-like GroES-like 22
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain SAM/Pointed domain 22
DNA clamp DNA clamp 21
Zinc beta-ribbon Cyclin-like 22
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
GroES-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
NAD(P)-binding Rossmann-fold domains Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 22
N-terminal, heterodimerisation domain of RBP7 (RpoE) Nucleic acid-binding proteins 21
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 22
beta-beta-alpha zinc fingers beta-beta-alpha zinc fingers 22
Translational machinery components L30e-like 22
P-loop containing nucleoside triphosphate hydrolases RNA-binding domain, RBD 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Protein kinase-like (PK-like) KA1-like 11
DNase I-like DNase I-like 11
Kelch motif Metallo-dependent phosphatases 11
Macro domain-like Zn-dependent exopeptidases 11
PH domain-like C2 domain (Calcium/lipid-binding domain, CaLB) 11
Thiamin diphosphate-binding fold (THDP-binding) Flavoproteins 11
WWE domain RING/U-box 11
BRCT domain P-loop containing nucleoside triphosphate hydrolases 11
Ubiquitin-like XPC-binding domain 11
Glucocorticoid receptor-like (DNA-binding domain) RING/U-box 11
Trimeric LpxA-like enzymes Trimeric LpxA-like enzymes 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Retrovirus zinc finger-like domains RING/U-box 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
UBC-like UBA-like 11
PLP-dependent transferases PLP-dependent transferases 11
ENTH/VHS domain ARM repeat 11
Clathrin adaptor appendage domain Subdomain of clathrin and coatomer appendage domain 11
FYVE/PHD zinc finger P-loop containing nucleoside triphosphate hydrolases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
TRAF domain-like ARM repeat 11
RNA-binding domain, RBD WW domain 11
P-loop containing nucleoside triphosphate hydrolases WD40 repeat-like 11
Ubiquitin-like Acid proteases 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
SNARE-like P-loop containing nucleoside triphosphate hydrolases 11
Thiamin diphosphate-binding fold (THDP-binding) Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Creatinase/aminopeptidase PH domain-like 11
Ribonuclease H-like Ribonuclease H-like 11
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Activating enzymes of the ubiquitin-like proteins Activating enzymes of the ubiquitin-like proteins 11
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
Class II aaRS and biotin synthetases Translation proteins 11
P-loop containing nucleoside triphosphate hydrolases PRTase-like 11
Nucleotidylyl transferase Nucleotidylyl transferase 11
Lipase/lipooxygenase domain (PLAT/LH2 domain) Concanavalin A-like lectins/glucanases 11
RING/U-box FYVE/PHD zinc finger 11
Single hybrid motif ClpP/crotonase 11
SMAD/FHA domain BRCT domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
PAH2 domain PAH2 domain 11
Growth factor receptor domain Hairpin loop containing domain-like 11
MIT domain P-loop containing nucleoside triphosphate hydrolases 11
Activator of Hsp90 ATPase, Aha1 Activator of Hsp90 ATPase, Aha1 11
"Winged helix" DNA-binding domain E2F-DP heterodimerization region 11
PH domain-like BEACH domain 11
Starch-binding domain-like EF-hand 11
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Chromo domain-like Bromodomain 11
Nucleic acid-binding proteins eIF2alpha middle domain-like 11
Dom34/Pelota N-terminal domain-like Translational machinery components 11
HMA, heavy metal-associated domain HAD-like 11
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
TK C-terminal domain-like Flavoproteins 11
Lipase/lipooxygenase domain (PLAT/LH2 domain) SRCR-like 11
SMAD/FHA domain SMAD/FHA domain 11
PUA domain-like eIF1-like 11
EF-hand SAICAR synthase-like 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
beta-beta-alpha zinc fingers S-adenosyl-L-methionine-dependent methyltransferases 11
CRAL/TRIO N-terminal domain Supernatant protein factor (SPF), C-terminal domain 11
Starch-binding domain-like Protein kinase-like (PK-like) 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
cAMP-binding domain-like Protein kinase-like (PK-like) 11
Mannose 6-phosphate receptor domain YccV-like 11
ADP-ribosylation B-box zinc-binding domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
TRAF domain-like Cysteine proteinases 11
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 11
Ribokinase-like Ribokinase-like 11
Concanavalin A-like lectins/glucanases Amine oxidase catalytic domain 11
TK C-terminal domain-like 4Fe-4S ferredoxins 11
EF-hand Metallo-dependent phosphatases 11
PH domain-like Oxysterol-binding protein-like 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
RCC1/BLIP-II Chromo domain-like 11
RING/U-box Ran binding protein zinc finger-like 11
Dihydrofolate reductase-like Thymidylate synthase/dCMP hydroxymethylase 11
Taf5 N-terminal domain-like WD40 repeat-like 11
PUG domain-like Ubiquitin-like 11
ARM repeat "Winged helix" DNA-binding domain 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Thiamin diphosphate-binding fold (THDP-binding) Riboflavin synthase domain-like 11
RING/U-box Homeodomain-like 11
WD40 repeat-like Bromodomain 11
UDP-Glycosyltransferase/glycogen phosphorylase HAD-like 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III Riboflavin synthase domain-like 11
PreATP-grasp domain Single hybrid motif 11
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 L30e-like 11
Thiamin diphosphate-binding fold (THDP-binding) 4Fe-4S ferredoxins 11
Translation initiation factor 2 beta, aIF2beta, N-terminal domain ARM repeat 11
NTF2-like RNA-binding domain, RBD 11
Oligoxyloglucan reducing end-specific cellobiohydrolase Oligoxyloglucan reducing end-specific cellobiohydrolase 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
Surp module (SWAP domain) Surp module (SWAP domain) 11
Glucocorticoid receptor-like (DNA-binding domain) AN1-like Zinc finger 11
ARM repeat P-loop containing nucleoside triphosphate hydrolases 11
CCCH zinc finger RING/U-box 11
Pre-PUA domain PUA domain-like 11
Pseudouridine synthase PUA domain-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Trimeric LpxA-like enzymes ARM repeat 11
Ribosomal protein L6 Ribosomal protein L6 11
SRCR-like Concanavalin A-like lectins/glucanases 11
P-loop containing nucleoside triphosphate hydrolases EF-hand 11
Zinc beta-ribbon Zinc beta-ribbon 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
Chaperone J-domain E set domains 11
P-loop containing nucleoside triphosphate hydrolases HAND domain of the nucleosome remodeling ATPase ISWI 11
PreATP-grasp domain ClpP/crotonase 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Hect, E3 ligase catalytic domain Hect, E3 ligase catalytic domain 11
AN1-like Zinc finger AN1-like Zinc finger 11
E set domains Glycosyl hydrolase domain 11
tRNA-binding arm Class II aaRS and biotin synthetases 11
TPR-like RNA-binding domain, RBD 11
(Trans)glycosidases Six-hairpin glycosidases 11
Chaperone J-domain Homeodomain-like 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
NSFL1 (p97 ATPase) cofactor p47, SEP domain Ubiquitin-like 11
ADC-like Cdc48 domain 2-like 11
WD40 repeat-like Quinoprotein alcohol dehydrogenase-like 11
SNARE-like Domain of the SRP/SRP receptor G-proteins 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III Ferredoxin reductase-like, C-terminal NADP-linked domain 11
WD40 repeat-like Cyclophilin-like 11
(Trans)glycosidases UDP-Glycosyltransferase/glycogen phosphorylase 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
SET domain Ankyrin repeat 11
Sec63 N-terminal domain-like Sec63 N-terminal domain-like 11
(Phosphotyrosine protein) phosphatases II PUG domain-like 11
PX domain WD40 repeat-like 11
Acid proteases UBA-like 11
UBA-like XPC-binding domain 11
Voltage-gated potassium channels E set domains 11
Zinc-binding domain of translation initiation factor 2 beta ARM repeat 11
E set domains E set domains 11
Dom34/Pelota N-terminal domain-like L30e-like 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
P-loop containing nucleoside triphosphate hydrolases E set domains 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
WD40 repeat-like Nitrous oxide reductase, N-terminal domain 11
alpha/beta knot Nucleic acid-binding proteins 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
vWA-like Cysteine-rich domain 11
Elongation factor TFIIS domain 2 Zinc beta-ribbon 11
RNA-binding domain, RBD Clavaminate synthase-like 11
Ankyrin repeat S-adenosyl-L-methionine-dependent methyltransferases 11
Carbamate kinase-like PUA domain-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Phosphoglycerate mutase-like 11
SET domain HIT/MYND zinc finger-like 11
UBA-like UBA-like 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Hypothetical protein AF0491, middle domain beta-beta-alpha zinc fingers 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Calcium ATPase, transmembrane domain M Nucleotide cyclase 11
EF-hand cAMP-binding domain-like 11
Ankyrin repeat Arginase/deacetylase 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
CRAL/TRIO domain GTPase activation domain, GAP 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Cdc48 domain 2-like P-loop containing nucleoside triphosphate hydrolases 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Translation proteins ThrRS/AlaRS common domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
ClpP/crotonase ClpP/crotonase 11
EGF/Laminin Hairpin loop containing domain-like 11
PreATP-grasp domain Rudiment single hybrid motif 11
HAND domain of the nucleosome remodeling ATPase ISWI Homeodomain-like 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
PriA/YqbF domain GINS helical bundle-like 11
RING/U-box RNA-binding domain, RBD 11
CRAL/TRIO domain Supernatant protein factor (SPF), C-terminal domain 11
Ankyrin repeat Hect, E3 ligase catalytic domain 11
Metallo-hydrolase/oxidoreductase Metallo-hydrolase/oxidoreductase 11
HAD-like HAD-like 11
BRCT domain post-AAA+ oligomerization domain-like 11
SNARE fusion complex SNARE fusion complex 11
PH domain-like PLC-like phosphodiesterases 11
CCCH zinc finger RNA-binding domain, RBD 11
FYVE/PHD zinc finger ARM repeat 11
CYTH-like phosphatases S-adenosyl-L-methionine-dependent methyltransferases 11
WD40 repeat-like Ribonuclease H-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Chaperone J-domain CSL zinc finger 11
Bromodomain SET domain 11
PH domain-like EF-hand 11
TPR-like Formin homology 2 domain (FH2 domain) 11
Homeodomain-like CHY zinc finger-like 11
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
Cyclophilin-like RNA-binding domain, RBD 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
POZ domain Skp1 dimerisation domain-like 11
Calcium ATPase, transduction domain A Nucleotide cyclase 11
t-snare proteins SNARE fusion complex 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Chaperone J-domain Sec63 N-terminal domain-like 11
Cysteine-rich domain NAD kinase/diacylglycerol kinase-like 11
SRCR-like SRCR-like 11
eIF2alpha middle domain-like eIF-2-alpha, C-terminal domain 11
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Translational machinery components 11
Class II aaRS and biotin synthetases C-terminal domain of ProRS 11
Ankyrin repeat Complement control module/SCR domain 11
RNI-like RNI-like 11
Trimeric LpxA-like enzymes HAD-like 11
Ankyrin repeat PH domain-like 11
Lipase/lipooxygenase domain (PLAT/LH2 domain) LCCL domain 11
WD40 repeat-like Cysteine proteinases 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
GMP synthetase C-terminal dimerisation domain GMP synthetase C-terminal dimerisation domain 11
TK C-terminal domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III Flavoproteins 11
Concanavalin A-like lectins/glucanases Concanavalin A-like lectins/glucanases 11
GST C-terminal domain-like eEF1-gamma domain 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 4Fe-4S ferredoxins 11
Calponin-homology domain, CH-domain EB1 dimerisation domain-like 11
Concanavalin A-like lectins/glucanases Hect, E3 ligase catalytic domain 11
Nucleotide-diphospho-sugar transferases ARM repeat 11
Rudiment single hybrid motif Single hybrid motif 11
Eukaryotic type KH-domain (KH-domain type I) Retrovirus zinc finger-like domains 11
Sec7 domain Ypt/Rab-GAP domain of gyp1p 11
4Fe-4S ferredoxins Flavoproteins 11
Zinc hairpin stack RING/U-box 11
YbaK/ProRS associated domain Class II aaRS and biotin synthetases 11
ARM repeat Subdomain of clathrin and coatomer appendage domain 11
LCCL domain LCCL domain 11
Radical SAM enzymes Acyl-CoA N-acyltransferases (Nat) 11
Acyl-CoA binding protein Ankyrin repeat 11
"Winged helix" DNA-binding domain Zinc beta-ribbon 11
Ankyrin repeat Ankyrin repeat 11
PLC-like phosphodiesterases C2 domain (Calcium/lipid-binding domain, CaLB) 11
PRP4-like WD40 repeat-like 11
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Cullin repeat-like Cullin repeat-like 11
E set domains Six-hairpin glycosidases 11
FYVE/PHD zinc finger Bromodomain 11
TPR-like Activator of Hsp90 ATPase, Aha1 11
(Phosphotyrosine protein) phosphatases II (Phosphotyrosine protein) phosphatases II 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 Elongation factor TFIIS domain 2 11
CHY zinc finger-like RING/U-box 11
PR-1-like PR-1-like 11
Nucleic acid-binding proteins TPR-like 11
DNA polymerase beta, N-terminal domain-like Restriction endonuclease-like 11
Kelch motif ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
FYSH domain beta-beta-alpha zinc fingers 11
FYSH domain Hypothetical protein AF0491, middle domain 11
LCCL domain Concanavalin A-like lectins/glucanases 11
TPR-like Metallo-dependent phosphatases 11
Ankyrin repeat TPR-like 11
(Trans)glycosidases (Trans)glycosidases 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
ATP-dependent DNA ligase DNA-binding domain Nucleic acid-binding proteins 11
Glutathione synthetase ATP-binding domain-like ClpP/crotonase 11
TK C-terminal domain-like Riboflavin synthase domain-like 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
Clathrin heavy-chain terminal domain ARM repeat 11
ThrRS/AlaRS common domain Nucleotidylyl transferase 11
dsRNA-binding domain-like P-loop containing nucleoside triphosphate hydrolases 11
RING/U-box WD40 repeat-like 11
4Fe-4S ferredoxins Riboflavin synthase domain-like 11
ALDH-like Dehydroquinate synthase-like 11
MFS general substrate transporter MFS general substrate transporter 11
Putative DNA-binding domain Putative DNA-binding domain 11
EF-hand PLC-like phosphodiesterases 11
EF-hand C2 domain (Calcium/lipid-binding domain, CaLB) 11
Nucleotidyltransferase PAP/Archaeal CCA-adding enzyme, C-terminal domain 11
TRAF domain-like POZ domain 11
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 Zinc beta-ribbon 11
Thioredoxin-like FAD-dependent thiol oxidase 11
CCCH zinc finger WD40 repeat-like 11
YbaK/ProRS associated domain C-terminal domain of ProRS 11
Putative isomerase YbhE WD40 repeat-like 11
Galactose mutarotase-like (Trans)glycosidases 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Bromodomain Bromodomain 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
Nucleic acid-binding proteins Eukaryotic type KH-domain (KH-domain type I) 11
Initiation factor IF2/eIF5b, domain 3 Translation proteins 11
Cysteine proteinases Ribonuclease H-like 11
ATP-dependent DNA ligase DNA-binding domain DNA ligase/mRNA capping enzyme, catalytic domain 11
Activating enzymes of the ubiquitin-like proteins Rhodanese/Cell cycle control phosphatase 11
CHY zinc finger-like Zinc hairpin stack 11
LCCL domain SRCR-like 11
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 11
GST C-terminal domain-like eEF-1beta-like 11
Eukaryotic RPB5 N-terminal domain RPB5-like RNA polymerase subunit 11
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment DNA breaking-rejoining enzymes 11
Cdc48 domain 2-like RING/U-box 11
Class II aaRS ABD-related C-terminal domain of ProRS 11
Chaperone J-domain beta-beta-alpha zinc fingers 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
PK beta-barrel domain-like PK C-terminal domain-like 11
Dcp2 domain-like Nudix 11
Ubiquitin-like Cysteine proteinases 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
RNA-binding domain, RBD Eukaryotic type KH-domain (KH-domain type I) 11
4Fe-4S ferredoxins P-loop containing nucleoside triphosphate hydrolases 11
PLP-dependent transferases Adenine nucleotide alpha hydrolases-like 11
ARM repeat RING/U-box 11
Ribonuclease H-like HRDC-like 11
4Fe-4S ferredoxins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
RNA-binding domain, RBD PABC (PABP) domain 11
TSP-1 type 1 repeat Kringle-like 11
PAP/OAS1 substrate-binding domain PAP/Archaeal CCA-adding enzyme, C-terminal domain 11
WD40 repeat-like Nucleoporin domain 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
"Winged helix" DNA-binding domain E set domains 11
"Winged helix" DNA-binding domain Protein kinase-like (PK-like) 11
GST C-terminal domain-like Nucleic acid-binding proteins 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Ankyrin repeat Bromodomain 11
Rudiment single hybrid motif ClpP/crotonase 11
Nucleic acid-binding proteins eIF-2-alpha, C-terminal domain 11
PRP4-like Functional domain of the splicing factor Prp18 11
Acyl-CoA N-acyltransferases (Nat) Bromodomain 11
TATA-box binding protein-like DNA-glycosylase 11

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