SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Bdellovibrio bacteriovorus HD100

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


Add or remove domain pairs

The links below permit the addition or removal of specific sets of domain combination pairs.


Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Add or remove genomes

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Add or remove genomes:
Include genomes:
Exclude genomes:


Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

558 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 3922
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2815
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1713
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 1612
Homodimeric domain of signal transducing histidine kinase CheY-like 1511
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 1511
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 151
Actin-like ATPase domain Actin-like ATPase domain 133
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 125
TPR-like TPR-like 119
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 84
RCC1/BLIP-II RCC1/BLIP-II 87
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 73
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 77
CheY-like Homeodomain-like 72
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 73
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 73
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 73
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 74
Ribosomal protein S5 domain 2-like P-loop containing nucleoside triphosphate hydrolases 75
PYP-like sensor domain (PAS domain) CheY-like 76
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 74
Phospholipase D/nuclease Phospholipase D/nuclease 73
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 73
CheY-like P-loop containing nucleoside triphosphate hydrolases 61
P-loop containing nucleoside triphosphate hydrolases Translation proteins 65
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 62
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
CalX-like RCC1/BLIP-II 65
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 63
Thiolase-like Thiolase-like 61
Class II aaRS and biotin synthetases Class II aaRS ABD-related 54
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 53
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 52
cAMP-binding domain-like "Winged helix" DNA-binding domain 51
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 53
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 54
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 55
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 53
CheY-like C-terminal effector domain of the bipartite response regulators 52
GAF domain-like Homodimeric domain of signal transducing histidine kinase 55
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 54
Triger factor/SurA peptide-binding domain-like FKBP-like 43
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 43
PDZ domain-like ClpP/crotonase 42
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 41
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 41
Nucleic acid-binding proteins Nucleic acid-binding proteins 44
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 44
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 44
GroES-like NAD(P)-binding Rossmann-fold domains 42
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 42
PurM N-terminal domain-like PurM C-terminal domain-like 42
Calcium ATPase, transmembrane domain M HAD-like 44
Calcium ATPase, transduction domain A HAD-like 44
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
Thioredoxin-like GST C-terminal domain-like 41
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
EF-G C-terminal domain-like EF-G C-terminal domain-like 43
PGBD-like L,D-transpeptidase catalytic domain-like 41
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 42
Translation proteins EF-G C-terminal domain-like 43
TrkA C-terminal domain-like TrkA C-terminal domain-like 32
PDZ domain-like PDZ domain-like 33
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 32
(Trans)glycosidases Glycosyl hydrolase domain 32
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 33
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 33
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 33
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 32
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 32
PUA domain-like Ribosomal protein S5 domain 2-like 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 33
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
cAMP-binding domain-like CheY-like 32
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 31
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
PreATP-grasp domain Rudiment single hybrid motif 32
Nucleic acid-binding proteins RuvA domain 2-like 33
Lysozyme-like beta-lactamase/transpeptidase-like 33
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 31
GAF domain-like CheY-like 33
PLP-binding barrel Alanine racemase C-terminal domain-like 32
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 33
Alpha-L RNA-binding motif Pseudouridine synthase 31
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 31
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 33
Cytochrome c Cytochrome c 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 21
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 22
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 22
Trypsin-like serine proteases PDZ domain-like 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Cupredoxins Cytochrome c 22
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 21
CheY-like Methylesterase CheB, C-terminal domain 22
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 21
ISP domain FAD/NAD(P)-binding domain 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 22
Bacterial muramidases Lysozyme-like 21
Single hybrid motif CoA-dependent acyltransferases 22
ClpP/crotonase ClpP/crotonase 21
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 21
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 21
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 22
Formyltransferase FMT C-terminal domain-like 21
Translation proteins Ribosomal protein S5 domain 2-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
HD-domain/PDEase-like ACT-like 22
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 21
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 21
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
Subtilisin-like Galactose-binding domain-like 22
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 22
CheY-like Nucleotide cyclase 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
HMA, heavy metal-associated domain HAD-like 22
HAMP domain-like PYP-like sensor domain (PAS domain) 22
Nucleotidyltransferase HD-domain/PDEase-like 22
Histidine-containing phosphotransfer domain, HPT domain CheW-like 22
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 21
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
Aconitase iron-sulfur domain LeuD/IlvD-like 21
SMAD/FHA domain TPR-like 22
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 22
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
Fibrinogen C-terminal domain-like Fibrinogen C-terminal domain-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Spermadhesin, CUB domain RCC1/BLIP-II 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
CheY-like Histidine-containing phosphotransfer domain, HPT domain 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
Periplasmic binding protein-like I Periplasmic binding protein-like II 21
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
HAMP domain-like CheY-like 22
Nucleotidyltransferase ACT-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 22
Integrin alpha N-terminal domain Integrin alpha N-terminal domain 22
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 22
Fibronectin type III Integrin alpha N-terminal domain 22
Spermadhesin, CUB domain CalX-like 22
Pseudouridine synthase S-adenosyl-L-methionine-dependent methyltransferases 11
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 11
Nucleotidylyl transferase Riboflavin kinase-like 11
P-loop containing nucleoside triphosphate hydrolases Probable GTPase Der, C-terminal domain 11
Nucleotidylyl transferase Nucleotidyltransferase 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Class II aaRS and biotin synthetases SufE/NifU 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
FAD-linked oxidoreductase ALDH-like 11
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Nucleotidyltransferase 11
CheY-like EspE N-terminal domain-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
GroES-like GroES-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Alkaline phosphatase-like alpha/beta-Hydrolases 11
TPR-like Nucleotide cyclase 11
MOSC N-terminal domain-like PK beta-barrel domain-like 11
LysM domain LysM domain 11
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
ADC-like 4Fe-4S ferredoxins 11
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
Bet v1-like Bet v1-like 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Zinc beta-ribbon DNA primase core 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
TPR-like Lysozyme-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Class II aaRS and biotin synthetases Translation proteins 11
PPK N-terminal domain-like PHP14-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
MalF N-terminal region-like MetI-like 11
PA domain Subtilisin-like 11
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
DPP6 N-terminal domain-like NHL repeat 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 11
YWTD domain YWTD domain 11
TATA-box binding protein-like DNA-glycosylase 11
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Regulatory protein AraC Homeodomain-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Nucleic acid-binding proteins GAD domain-like 11
Lysozyme-like LysM domain 11
CBS-domain pair MgtE membrane domain-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
E set domains Glycosyl hydrolase domain 11
RNase III domain-like dsRNA-binding domain-like 11
Homeodomain-like TATA-box binding protein-like 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
GroEL equatorial domain-like GroEL apical domain-like 11
Nucleotide cyclase ARM repeat 11
Thioredoxin-like TPR-like 11
Periplasmic binding protein-like II MetI-like 11
Penicillin binding protein dimerisation domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
MgtE N-terminal domain-like CBS-domain pair 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
Macro domain-like Zn-dependent exopeptidases 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
CheY-like CheC-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Cytidine deaminase-like Nudix 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Putative DNA-binding domain Cobalamin (vitamin B12)-binding domain 11
Translation proteins PRC-barrel domain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
P-loop containing nucleoside triphosphate hydrolases Aminoacid dehydrogenase-like, N-terminal domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Subtilisin-like PilZ domain-like 11
CarD-like TRCF domain-like 11
PLP-dependent transferases PLP-dependent transferases 11
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
beta-lactamase/transpeptidase-like Penicillin-binding protein 2x (pbp-2x), c-terminal domain 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
P-loop containing nucleoside triphosphate hydrolases Aldolase 11
lambda repressor-like DNA-binding domains RmlC-like cupins 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
PreATP-grasp domain PreATP-grasp domain 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Cobalamin (vitamin B12)-binding domain Radical SAM enzymes 11
HAMP domain-like Nucleotide cyclase 11
PKD domain PKD domain 11
Nucleotidyltransferase Nucleotidyltransferase 11
Aldolase AFP III-like domain 11
Sialidases Sialidases 11
HCP-like C-terminal effector domain of the bipartite response regulators 11
TGS-like ThrRS/AlaRS common domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
PA domain Zn-dependent exopeptidases 11
Ribosomal protein L6 Ribosomal protein L6 11
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
Cupredoxins Cupredoxins 11
NAD(P)-binding Rossmann-fold domains RmlC-like cupins 11
Carbamate kinase-like ACT-like 11
SMAD/FHA domain P-loop containing nucleoside triphosphate hydrolases 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
PRTase-like alpha/beta-Hydrolases 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Nqo5-like HydB/Nqo4-like 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
Thioredoxin-like Thioredoxin-like 11
P-loop containing nucleoside triphosphate hydrolases Cobalamin (vitamin B12)-dependent enzymes 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
ABC transporter transmembrane region ABC transporter transmembrane region 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
ISP domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
CNF1/YfiH-like putative cysteine hydrolases CheY-like 11
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Translation proteins ThrRS/AlaRS common domain 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Fibronectin type III Concanavalin A-like lectins/glucanases 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
HD-domain/PDEase-like TGS-like 11
Trigger factor ribosome-binding domain FKBP-like 11
L30e-like alpha/beta knot 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
CNF1/YfiH-like putative cysteine hydrolases Methylesterase CheB, C-terminal domain 11
Fibronectin type III Anthrax protective antigen 11
TGS-like ACT-like 11
Cobalamin (vitamin B12)-binding domain P-loop containing nucleoside triphosphate hydrolases 11
PIN domain-like DNA/RNA polymerases 11
cAMP-binding domain-like cAMP-binding domain-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
FMN-binding split barrel GAF domain-like 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
FliG FliG 11
Subtilisin-like Spermadhesin, CUB domain 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
Class II aaRS and biotin synthetases C-terminal domain of ProRS 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
CheC-like Surface presentation of antigens (SPOA) 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Spermadhesin, CUB domain Spermadhesin, CUB domain 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
CalX-like Fibronectin type III 11
TGS-like Class II aaRS and biotin synthetases 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
ClpP/crotonase NfeD domain-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Periplasmic binding protein-like II Lysozyme-like 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
ACT-like ACT-like 11
S-adenosylmethionine decarboxylase S-adenosyl-L-methionine-dependent methyltransferases 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
NAD-binding domain of HMG-CoA reductase Substrate-binding domain of HMG-CoA reductase 11
DPP6 N-terminal domain-like PA domain 11
DNA methylase specificity domain DNA methylase specificity domain 11
E set domains (Trans)glycosidases 11
CBS-domain pair Nucleotide-diphospho-sugar transferases 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) TATA-box binding protein-like 11
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
L,D-transpeptidase catalytic domain-like NTF2-like 11
Ribonuclease H-like RuvA domain 2-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
MetI-like MetI-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Nucleotidyltransferase Acyl-CoA N-acyltransferases (Nat) 11
Ribonuclease H-like Nucleic acid-binding proteins 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Zn-dependent exopeptidases PDZ domain-like 11
PheT/TilS domain Putative DNA-binding domain 11
SMAD/FHA domain SMAD/FHA domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Hsp33 domain HSP33 redox switch-like 11
Rhodanese/Cell cycle control phosphatase P-loop containing nucleoside triphosphate hydrolases 11
Subtilisin-like Invasin/intimin cell-adhesion fragments 11
GroEL-intermediate domain like GroEL apical domain-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
DPP6 N-terminal domain-like Zn-dependent exopeptidases 11
GIY-YIG endonuclease RuvA domain 2-like 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 11
Translation proteins Translation proteins 11
RuvA domain 2-like RuvA domain 2-like 11
RuvA domain 2-like BRCT domain 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
PKD domain Hedgehog/intein (Hint) domain 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
TGS-like Class II aaRS ABD-related 11
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase 3-carboxy-cis,cis-mucoante lactonizing enzyme 11
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 11
Fibronectin type III Fibronectin type III 11
PA domain PDZ domain-like 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Nucleic acid-binding proteins PheT/TilS domain 11
DPP6 N-terminal domain-like alpha/beta-Hydrolases 11
Nucleotidylyl transferase tRNA-binding arm 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
P-loop containing nucleoside triphosphate hydrolases Myosin rod fragments 11
GAF domain-like Homeodomain-like 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
YrdC/RibB RibA-like 11
Aldolase Aminoacid dehydrogenase-like, N-terminal domain 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
Tex N-terminal region-like Ribonuclease H-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
CheY-like CheY-like 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 11
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
CalX-like CalX-like 11
Ribonuclease H-like GIY-YIG endonuclease 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
DNA clamp DNA clamp 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Single hybrid motif Single hybrid motif 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Nucleotidyltransferase TGS-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
Homeodomain-like DNA-glycosylase 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) DNA-glycosylase 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
DPP6 N-terminal domain-like DPP6 N-terminal domain-like 11
NHL repeat Calcium-dependent phosphotriesterase 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Class II aaRS ABD-related C-terminal domain of ProRS 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
ISP domain Flavoproteins 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
PHP14-like Phospholipase D/nuclease 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
NAD(P)-binding Rossmann-fold domains Bet v1-like 11
PUA domain-like alpha/beta knot 11
NHL repeat NHL repeat 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Nucleic acid-binding proteins BRCT domain 11
Inosine monophosphate dehydrogenase (IMPDH) Inosine monophosphate dehydrogenase (IMPDH) 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
P-loop containing nucleoside triphosphate hydrolases MOP-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
cAMP-binding domain-like EAL domain-like 11
TSP-1 type 1 repeat Hedgehog/intein (Hint) domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
SMAD/FHA domain Nucleotide cyclase 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
TPR-like C-terminal effector domain of the bipartite response regulators 11
SMAD/FHA domain Homeodomain-like 11
Tex N-terminal region-like RuvA domain 2-like 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Cobalamin (vitamin B12)-binding domain Cobalamin (vitamin B12)-dependent enzymes 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
Prim-pol domain DNA/RNA polymerases 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
CheW-like CheW-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
PYP-like sensor domain (PAS domain) GAF domain-like 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
PKD domain TSP-1 type 1 repeat 11
Periplasmic binding protein-like II MalF N-terminal region-like 11
Pili subunits Pili subunits 11
ISP domain Bet v1-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
YajQ-like YajQ-like 11
Cytochrome c oxidase subunit I-like Cytochrome c 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Fibronectin type III RCC1/BLIP-II 11
alpha/beta-Hydrolases Acetyl-CoA synthetase-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
DPP6 N-terminal domain-like PDZ domain-like 11
DNA repair protein MutS, domain III SMR domain-like 11
Periplasmic binding protein-like II Periplasmic binding protein-like II 11
Nucleic acid-binding proteins HD-domain/PDEase-like 11

Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes · Domain combination pairs ]