SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Burkholderia xenovorans LB400

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

846 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 1722
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 6424
Homeodomain-like Homeodomain-like 548
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 5316
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 503
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 477
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 423
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 413
"Winged helix" DNA-binding domain GAF domain-like 372
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 376
GroES-like NAD(P)-binding Rossmann-fold domains 342
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 328
CheY-like C-terminal effector domain of the bipartite response regulators 313
Thiolase-like Thiolase-like 292
ISP domain Bet v1-like 283
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 2616
Homodimeric domain of signal transducing histidine kinase CheY-like 2515
Actin-like ATPase domain Actin-like ATPase domain 248
Thioredoxin-like GST C-terminal domain-like 241
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 248
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 228
P-loop containing nucleoside triphosphate hydrolases MOP-like 222
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 219
Class I glutamine amidotransferase-like Homeodomain-like 201
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 204
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 204
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 209
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 191
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1812
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 183
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 181
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 178
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 178
Cytochrome c Cytochrome c 177
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 178
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 174
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 174
Nucleotide cyclase EAL domain-like 179
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 178
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 171
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 178
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 163
"Winged helix" DNA-binding domain PLP-dependent transferases 161
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 154
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 1510
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 156
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 143
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 149
PYP-like sensor domain (PAS domain) Nucleotide cyclase 138
Homeodomain-like Ribonuclease H-like 135
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 133
"Winged helix" DNA-binding domain Chorismate lyase-like 131
Enolase N-terminal domain-like Enolase C-terminal domain-like 131
cAMP-binding domain-like "Winged helix" DNA-binding domain 122
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 124
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 123
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 113
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 116
Homeodomain-like SIS domain 112
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 113
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 113
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 111
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 111
PYP-like sensor domain (PAS domain) CheY-like 117
P-loop containing nucleoside triphosphate hydrolases Translation proteins 106
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 104
PYP-like sensor domain (PAS domain) EAL domain-like 95
RmlC-like cupins Homeodomain-like 93
HAD-like Calcium ATPase, transmembrane domain M 84
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 84
Calcium ATPase, transduction domain A HAD-like 84
lambda repressor-like DNA-binding domains RmlC-like cupins 82
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 84
Regulatory protein AraC Homeodomain-like 83
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 84
PreATP-grasp domain Rudiment single hybrid motif 84
CheY-like CheY-like 85
Phospholipase D/nuclease Phospholipase D/nuclease 86
Aspartate receptor, ligand-binding domain Methyl-accepting chemotaxis protein (MCP) signaling domain 83
FMN-binding split barrel UbiD C-terminal domain-like 74
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 74
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 73
HMA, heavy metal-associated domain Cation efflux protein transmembrane domain-like 71
HlyD-like secretion proteins HlyD-like secretion proteins 74
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 71
ParB/Sulfiredoxin KorB DNA-binding domain-like 71
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 74
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 61
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 64
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 62
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 61
Triger factor/SurA peptide-binding domain-like FKBP-like 64
GAF domain-like Homeodomain-like 63
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 62
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 64
GAF domain-like Homodimeric domain of signal transducing histidine kinase 64
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 61
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 63
PurM N-terminal domain-like PurM C-terminal domain-like 62
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 63
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 62
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 61
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 66
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 63
Phage tail proteins Phage tail proteins 53
GroEL-intermediate domain like GroEL apical domain-like 51
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 53
GroEL equatorial domain-like GroEL-intermediate domain like 51
CheY-like P-loop containing nucleoside triphosphate hydrolases 52
TPR-like TPR-like 54
GAF domain-like CheY-like 53
Translation proteins EF-G C-terminal domain-like 53
GAF domain-like Nucleotide cyclase 54
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 52
Aldolase post-HMGL domain-like 52
CheY-like Homeodomain-like 52
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 52
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 53
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 52
ClpP/crotonase ClpP/crotonase 53
Nucleotide-diphospho-sugar transferases RmlC-like cupins 51
GroEL equatorial domain-like GroEL apical domain-like 51
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 54
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 53
Ribosomal protein S5 domain 2-like P-loop containing nucleoside triphosphate hydrolases 54
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 53
ACT-like ACT-like 53
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 52
PYP-like sensor domain (PAS domain) Homeodomain-like 53
Alpha-L RNA-binding motif Pseudouridine synthase 54
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 42
Rudiment single hybrid motif Single hybrid motif 43
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 41
Phage tail proteins gp5 N-terminal domain-like 42
Glutathione synthetase ATP-binding domain-like Single hybrid motif 43
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 42
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 43
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 42
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 42
Galactose-binding domain-like Galactose-binding domain-like 41
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 42
(Trans)glycosidases Glycosyl hydrolase domain 43
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 43
Adhesin YadA, collagen-binding domain Adhesin YadA, collagen-binding domain 44
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 42
Cupredoxins Cytochrome c 42
PreATP-grasp domain Single hybrid motif 43
GAF domain-like EAL domain-like 43
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 42
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 42
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 44
PLP-binding barrel Alanine racemase C-terminal domain-like 42
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 42
Adhesin YadA, collagen-binding domain Pili subunits 44
EAL domain-like Sensory domain-like 42
E set domains (Trans)glycosidases 43
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 43
gp5 N-terminal domain-like Phage fibre proteins 42
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 42
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 41
Trypsin-like serine proteases PDZ domain-like 43
PYP-like sensor domain (PAS domain) GAF domain-like 43
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
Phage tail proteins Phage fibre proteins 42
P-loop containing nucleoside triphosphate hydrolases C-terminal effector domain of the bipartite response regulators 42
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 43
Lysozyme-like beta-lactamase/transpeptidase-like 43
EF-G C-terminal domain-like EF-G C-terminal domain-like 42
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 42
Methylesterase CheB, C-terminal domain CheY-like 32
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 33
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 32
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 31
HAMP domain-like Nucleotide cyclase 33
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 31
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 31
Nucleotidyltransferase ACT-like 32
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 32
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 31
E set domains Glycosyl hydrolase domain 32
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 33
MetI-like MetI-like 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Sm-like ribonucleoproteins cAMP-binding domain-like 33
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 33
PRC-barrel domain PRC-barrel domain 32
Folate-binding domain Aminomethyltransferase beta-barrel domain 33
CBS-domain pair FAD-binding/transporter-associated domain-like 32
MOP-like MOP-like 32
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 32
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 31
LeuD/IlvD-like Aconitase iron-sulfur domain 32
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 32
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 33
lambda repressor-like DNA-binding domains P-loop containing nucleoside triphosphate hydrolases 31
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 31
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 32
MFS general substrate transporter MFS general substrate transporter 31
Nucleic acid-binding proteins RuvA domain 2-like 33
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 31
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 32
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 31
PDZ domain-like PDZ domain-like 32
Galactose mutarotase-like Six-hairpin glycosidases 32
LysM domain Duplicated hybrid motif 31
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 32
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
Nucleotide cyclase Sensory domain-like 33
TPR-like P-loop containing nucleoside triphosphate hydrolases 32
HD-domain/PDEase-like ACT-like 32
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 32
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 32
alpha/beta-Hydrolases NTF2-like 31
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
CheY-like Histidine-containing phosphotransfer domain, HPT domain 33
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 33
alpha/beta-Hydrolases alpha/beta-Hydrolases 32
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 32
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 31
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 31
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 33
Translation proteins ThrRS/AlaRS common domain 32
Aspartate/glutamate racemase Aspartate/glutamate racemase 32
Cupredoxins Cupredoxins 33
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 31
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 32
Single hybrid motif CoA-dependent acyltransferases 32
Nucleotidyltransferase HD-domain/PDEase-like 32
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 32
Nqo1 middle domain-like Nqo1C-terminal domain-like 32
MetI-like P-loop containing nucleoside triphosphate hydrolases 33
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
TrpR-like Homeodomain-like 22
Methylesterase CheB, C-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 21
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 22
Thioesterase/thiol ester dehydrase-isomerase Isocitrate/Isopropylmalate dehydrogenase-like 21
L30e-like alpha/beta knot 21
HD-domain/PDEase-like TGS-like 21
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 21
H-NS histone-like proteins H-NS histone-like proteins 22
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
Acetyl-CoA synthetase-like CoA-dependent acyltransferases 22
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 22
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 21
HAMP domain-like PYP-like sensor domain (PAS domain) 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
TPR-like C-terminal effector domain of the bipartite response regulators 21
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 22
FAD/NAD(P)-binding domain Folate-binding domain 22
S-adenosyl-L-methionine-dependent methyltransferases Nucleotide-diphospho-sugar transferases 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 21
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 21
Chemotaxis receptor methyltransferase CheR, N-terminal domain PYP-like sensor domain (PAS domain) 21
MoeA N-terminal region -like MoeA C-terminal domain-like 22
Clc chloride channel CBS-domain pair 21
Nucleotidyltransferase TGS-like 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 22
Methylesterase CheB, C-terminal domain PYP-like sensor domain (PAS domain) 21
P-loop containing nucleoside triphosphate hydrolases ACT-like 21
EAL domain-like HD-domain/PDEase-like 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 22
PrpR receptor domain-like Homeodomain-like 21
GroES-like GroES-like 21
Translation proteins Ribosomal protein S5 domain 2-like 21
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 21
Acetyl-CoA synthetase-like ACP-like 22
4Fe-4S ferredoxins Riboflavin synthase domain-like 21
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 22
alpha-helical ferredoxin Nucleotide-binding domain 22
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 22
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 21
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 22
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
FAD/NAD(P)-binding domain HI0933 insert domain-like 21
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 22
Chemotaxis receptor methyltransferase CheR, N-terminal domain Homodimeric domain of signal transducing histidine kinase 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
PrpR receptor domain-like PYP-like sensor domain (PAS domain) 21
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Thioredoxin-like Nqo1 middle domain-like 21
CoA-dependent acyltransferases CoA-dependent acyltransferases 22
4Fe-4S ferredoxins Ferredoxin reductase-like, C-terminal NADP-linked domain 21
CoA-transferase family III (CaiB/BaiF) CoA-transferase family III (CaiB/BaiF) 21
S-adenosyl-L-methionine-dependent methyltransferases Homodimeric domain of signal transducing histidine kinase 21
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 21
S-adenosyl-L-methionine-dependent methyltransferases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 22
ACP-like CoA-dependent acyltransferases 22
ACP-like ACP-like 22
Galactose mutarotase-like Galactose mutarotase-like 21
Thioredoxin-like Nqo1C-terminal domain-like 21
TGS-like ACT-like 21
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 21
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 21
cAMP-binding domain-like FAD/NAD(P)-binding domain 21
Thioredoxin-like FAD/NAD(P)-binding domain 22
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
UDP-Glycosyltransferase/glycogen phosphorylase Nucleotide-diphospho-sugar transferases 22
Methylesterase CheB, C-terminal domain Homodimeric domain of signal transducing histidine kinase 21
PH0987 N-terminal domain-like Cyclophilin-like 22
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 21
Putative DNA-binding domain Citrate synthase 22
Oxidoreductase molybdopterin-binding domain E set domains 21
Methylesterase CheB, C-terminal domain Chemotaxis receptor methyltransferase CheR, N-terminal domain 21
Chemotaxis receptor methyltransferase CheR, N-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
Formyltransferase FMT C-terminal domain-like 21
PapD-like Periplasmic chaperone C-domain 22
PrpR receptor domain-like P-loop containing nucleoside triphosphate hydrolases 21
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 21
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 21
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 22
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 21
S-adenosyl-L-methionine-dependent methyltransferases UDP-Glycosyltransferase/glycogen phosphorylase 22
ACT-like Formyltransferase 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
Methylesterase CheB, C-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
Thioredoxin-like Nqo1 FMN-binding domain-like 21
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 21
Ribonuclease H-like DNA/RNA polymerases 22
RuBisCO, large subunit, small (N-terminal) domain RuBisCo, C-terminal domain 21
S-adenosyl-L-methionine-dependent methyltransferases PYP-like sensor domain (PAS domain) 21
TrkA C-terminal domain-like TrkA C-terminal domain-like 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 22
ALDH-like ALDH-like 21
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 21
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 22
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 22
Chemotaxis receptor methyltransferase CheR, N-terminal domain CheY-like 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
HMA, heavy metal-associated domain HAD-like 22
Nqo5-like HydB/Nqo4-like 21
S-adenosyl-L-methionine-dependent methyltransferases CheY-like 21
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 11
L domain-like Protein kinase-like (PK-like) 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Actin-like ATPase domain HD-domain/PDEase-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Hsp33 domain HSP33 redox switch-like 11
FAD-linked reductases, C-terminal domain Folate-binding domain 11
FAD/NAD(P)-binding domain Glutaminase/Asparaginase 11
TGS-like Class II aaRS and biotin synthetases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Carboxypeptidase regulatory domain-like Porins 11
beta-lactamase/transpeptidase-like beta-lactamase/transpeptidase-like 11
Putative DNA-binding domain Translation proteins 11
ADC-like Flavoproteins 11
PurS-like Class I glutamine amidotransferase-like 11
Ribbon-helix-helix FAD-linked oxidoreductase 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
PurS-like FGAM synthase PurL, linker domain 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
TGS-like ThrRS/AlaRS common domain 11
Rudiment single hybrid motif ClpP/crotonase 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Class II aaRS and biotin synthetases Translation proteins 11
Homodimeric domain of signal transducing histidine kinase Homodimeric domain of signal transducing histidine kinase 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Glutathione synthetase ATP-binding domain-like PH0987 N-terminal domain-like 11
AhpD-like AhpD-like 11
ATP-dependent DNA ligase DNA-binding domain Nucleic acid-binding proteins 11
Family A G protein-coupled receptor-like CBS-domain pair 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
PHP14-like Phospholipase D/nuclease 11
HCP-like HCP-like 11
Voltage-gated potassium channels E set domains 11
Acylphosphatase/BLUF domain-like Rhodanese/Cell cycle control phosphatase 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Cyclophilin-like Cyclophilin-like 11
Globin-like EAL domain-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
MesJ substrate recognition domain-like PheT/TilS domain 11
PPK N-terminal domain-like PHP14-like 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
cAMP-binding domain-like ABC transporter transmembrane region 11
PheT/TilS domain Putative DNA-binding domain 11
a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Phase 1 flagellin Phase 1 flagellin 11
Fe,Mn superoxide dismutase (SOD), C-terminal domain Rhodanese/Cell cycle control phosphatase 11
FAD-linked oxidases, C-terminal domain FAD-linked oxidases, C-terminal domain 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
DNA methylase specificity domain DNA methylase specificity domain 11
Glutathione synthetase ATP-binding domain-like ClpP/crotonase 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Cyclophilin-like 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Flavoproteins 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
SMAD/FHA domain SMAD/FHA domain 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
RuvA domain 2-like RuvA domain 2-like 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
ADC-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
FAD-linked reductases, C-terminal domain Aminomethyltransferase beta-barrel domain 11
Molybdenum cofactor-binding domain Bet v1-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Purple acid phosphatase, N-terminal domain Metallo-dependent phosphatases 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
CBS-domain pair Nucleotide cyclase 11
HAMP domain-like EAL domain-like 11
Radical SAM enzymes Nitrogenase accessory factor-like 11
4Fe-4S ferredoxins ADC-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Periplasmic binding protein-like II Cytochrome c 11
Actin-like ATPase domain Homeodomain-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Chitinase insertion domain PKD domain 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Histidine-containing phosphotransfer domain, HPT domain CheY-binding domain of CheA 11
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
PurS-like PurM N-terminal domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Tex N-terminal region-like Ribonuclease H-like 11
Cobalamin (vitamin B12)-binding domain Radical SAM enzymes 11
P-loop containing nucleoside triphosphate hydrolases Cobalamin (vitamin B12)-dependent enzymes 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
PIN domain-like DNA/RNA polymerases 11
LysM domain LysM domain 11
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
ClpP/crotonase NfeD domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Trypsin-like serine proteases PKD domain 11
Homeodomain-like Probable bacterial effector-binding domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Alkaline phosphatase-like Concanavalin A-like lectins/glucanases 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
PIN domain-like Ribonuclease H-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
PK beta-barrel domain-like PK C-terminal domain-like 11
ATP-dependent DNA ligase DNA-binding domain DNA ligase/mRNA capping enzyme, catalytic domain 11
Glycosyl hydrolase domain Protein kinase-like (PK-like) 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Thioredoxin-like TPR-like 11
YajQ-like YajQ-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
PreATP-grasp domain PreATP-grasp domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Rudiment single hybrid motif PH0987 N-terminal domain-like 11
FMN-binding split barrel Ferredoxin reductase-like, C-terminal NADP-linked domain 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
Ricin B-like lectins Integrin alpha N-terminal domain 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
Resolvase-like Homeodomain-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
EAL domain-like CBS-domain pair 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
Tropomyosin Smc hinge domain 11
cAMP-binding domain-like cAMP-binding domain-like 11
NagB/RpiA/CoA transferase-like 4Fe-4S ferredoxins 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
FKBP-like FKBP-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
CheY-binding domain of CheA CheW-like 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 11
Acetyl-CoA synthetase-like Acetyl-CoA synthetase-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
PUA domain-like alpha/beta knot 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Carbamate kinase-like ACT-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
DNA clamp DNA clamp 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
HMA, heavy metal-associated domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Nucleic acid-binding proteins BRCT domain 11
CheY-binding domain of CheA ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
RuvA domain 2-like BRCT domain 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain "Winged helix" DNA-binding domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Molybdenum cofactor-binding domain Cytochrome c 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Calcium-dependent phosphotriesterase NHL repeat 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
SMAD/FHA domain P-loop containing nucleoside triphosphate hydrolases 11
Dimeric alpha+beta barrel Dimeric alpha+beta barrel 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
Duplicated hybrid motif Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
lambda repressor-like DNA-binding domains lambda repressor-like DNA-binding domains 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
ISP domain FAD/NAD(P)-binding domain 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
Thermostable phytase (3-phytase) Lamin A/C globular tail domain 11
FMN-binding split barrel 2Fe-2S ferredoxin-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Duplicated hybrid motif HPr-like 11
"Winged helix" DNA-binding domain MOP-like 11
Acetyl-CoA synthetase-like Thioesterase/thiol ester dehydrase-isomerase 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Homeodomain-like Acetamidase/Formamidase-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Ribonuclease H-like GIY-YIG endonuclease 11
PreATP-grasp domain PH0987 N-terminal domain-like 11
LmbE-like Integrin alpha N-terminal domain 11
Flavoproteins Riboflavin synthase domain-like 11
Ribosomal protein L6 Ribosomal protein L6 11
Globin-like GAF domain-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Nucleotide-binding domain Nucleotide-binding domain 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
PLP-dependent transferases PLP-dependent transferases 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Sensory domain-like HAMP domain-like 11
CarD-like TRCF domain-like 11
Calcium-dependent phosphotriesterase Calcium-dependent phosphotriesterase 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
TGS-like Class II aaRS ABD-related 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Metallo-dependent phosphatases P-loop containing nucleoside triphosphate hydrolases 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
CO dehydrogenase molybdoprotein N-domain-like Cytochrome c 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases Tropomyosin 11
C-terminal effector domain of the bipartite response regulators C-terminal effector domain of the bipartite response regulators 11
(Trans)glycosidases PKD domain 11
Pseudouridine synthase PUA domain-like 11
RmlC-like cupins RmlC-like cupins 11
Cupredoxins OmpA-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
CheC-like Surface presentation of antigens (SPOA) 11
(Phosphotyrosine protein) phosphatases II FAD/NAD(P)-binding domain 11
Ribbon-helix-helix ACT-like 11
NHL repeat Thermostable phytase (3-phytase) 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 11
Periplasmic binding protein-like I Homeodomain-like 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Ferredoxin reductase-like, C-terminal NADP-linked domain 11
TPR-like Nucleotide cyclase 11
Rhodanese/Cell cycle control phosphatase Ankyrin repeat 11
Periplasmic binding protein-like II PYP-like sensor domain (PAS domain) 11
Cobalamin (vitamin B12)-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Single hybrid motif FAD/NAD(P)-binding domain 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Formylmethanofuran:tetrahydromethanopterin formyltransferase Formylmethanofuran:tetrahydromethanopterin formyltransferase 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Rudiment single hybrid motif Cyclophilin-like 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
MFS general substrate transporter S-adenosyl-L-methionine-dependent methyltransferases 11
FAD-linked oxidoreductase ALDH-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
Nucleotidylyl transferase tRNA-binding arm 11
Translation proteins "Winged helix" DNA-binding domain 11
Protease propeptides/inhibitors Subtilisin-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
YjeF N-terminal domain-like Ribokinase-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Cytochrome c oxidase subunit II-like, transmembrane region OmpA-like 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Adenine nucleotide alpha hydrolases-like GAF domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase PP2C-like 11
Caspase-like C-type lectin-like 11
Single hybrid motif alpha/beta-Hydrolases 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Trigger factor ribosome-binding domain FKBP-like 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
FMN-linked oxidoreductases Nucleotide-binding domain 11
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 11
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 11
Translation proteins PRC-barrel domain 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
TTHA1013/TTHA0281-like Ribbon-helix-helix 11
Periplasmic binding protein-like II Periplasmic binding protein-like II 11
FMN-dependent nitroreductase-like FMN-dependent nitroreductase-like 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
Duplicated hybrid motif Phosphoenolpyruvate/pyruvate domain 11
AhpD-like RmlC-like cupins 11
Bacterial luciferase-like Bacterial luciferase-like 11
TrpR-like Ribonuclease H-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
DAK1/DegV-like DhaL-like 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
Single hybrid motif ClpP/crotonase 11
Nucleic acid-binding proteins GAD domain-like 11
FliG FliG 11
Cytochrome c oxidase subunit I-like Cytochrome c oxidase subunit III-like 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
PDZ domain-like ClpP/crotonase 11
Translation proteins Translation proteins 11
Methionine synthase domain Methionine synthase activation domain-like 11
Chorismate mutase II Periplasmic binding protein-like II 11
FAD/NAD(P)-binding domain alpha/beta-Hydrolases 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
HMA, heavy metal-associated domain FAD/NAD(P)-binding domain 11
S-adenosyl-L-methionine-dependent methyltransferases EreA/ChaN-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Bacterial muramidases Lysozyme-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Pectin lyase-like Autotransporter 11
Globin-like Riboflavin synthase domain-like 11
CO dehydrogenase molybdoprotein N-domain-like Bet v1-like 11
(Trans)glycosidases (Trans)glycosidases 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
YdfO-like YdfO-like 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Family A G protein-coupled receptor-like FAD-binding/transporter-associated domain-like 11
Tex N-terminal region-like RuvA domain 2-like 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Rhodanese/Cell cycle control phosphatase P-loop containing nucleoside triphosphate hydrolases 11
ADC-like Riboflavin synthase domain-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Nucleic acid-binding proteins PheT/TilS domain 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Cytochrome c OmpA-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Metalloproteases ("zincins"), catalytic domain PDZ domain-like 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Rhodanese/Cell cycle control phosphatase 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
RNase III domain-like dsRNA-binding domain-like 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
PreATP-grasp domain Cyclophilin-like 11
Thioredoxin-like DinB/YfiT-like putative metalloenzymes 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
PH0987 N-terminal domain-like Single hybrid motif 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
ABC transporter involved in vitamin B12 uptake, BtuC ABC transporter involved in vitamin B12 uptake, BtuC 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
Nucleotide-diphospho-sugar transferases PilZ domain-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
DNA-glycosylase Nudix 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
CheY-binding domain of CheA Homodimeric domain of signal transducing histidine kinase 11
Zinc beta-ribbon DNA primase core 11
Single hybrid motif Single hybrid motif 11
Macro domain-like Zn-dependent exopeptidases 11
PurS-like PurM C-terminal domain-like 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
Thioredoxin-like Thioredoxin-like 11
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 11
Periplasmic binding protein-like II CheY-like 11
HprK N-terminal domain-like PEP carboxykinase-like 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Toll/Interleukin receptor TIR domain Staphylococcal nuclease 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
HPr-like Phosphohistidine domain 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
MOSC N-terminal domain-like PK beta-barrel domain-like 11
GAF domain-like GAF domain-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
ISP domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
CbiG N-terminal domain-like Tetrapyrrole methylase 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
PIN domain-like "Winged helix" DNA-binding domain 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
FMN-linked oxidoreductases 4Fe-4S ferredoxins 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Ribbon-helix-helix ALDH-like 11
PKD domain PKD domain 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Actin-like ATPase domain SIS domain 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
2Fe-2S ferredoxin-like ADC-like 11
Glutathione synthetase ATP-binding domain-like Acyl-CoA N-acyltransferases (Nat) 11
HPr-like Phosphoenolpyruvate/pyruvate domain 11
DHS-like NAD/FAD-binding domain Ribonuclease H-like 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
Carbamate kinase-like PUA domain-like 11
Mechanosensitive channel protein MscS (YggB), C-terminal domain cAMP-binding domain-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Heme-dependent catalase-like Class I glutamine amidotransferase-like 11
Chorismate mutase II ACT-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
Cobalamin (vitamin B12)-binding domain Cobalamin (vitamin B12)-dependent enzymes 11
cAMP-binding domain-like P-loop containing nucleoside triphosphate hydrolases 11
4Fe-4S ferredoxins Respiratory nitrate reductase 1 gamma chain 11
FMN-binding split barrel Riboflavin synthase domain-like 11
Cyclophilin-like Single hybrid motif 11
DNA topoisomerase I domain DNA breaking-rejoining enzymes 11
YrdC/RibB RibA-like 11
Glucose permease domain IIB Glucose permease domain IIB 11
(Trans)glycosidases Chitinase insertion domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Periplasmic binding protein-like II ACT-like 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Riboflavin synthase domain-like 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Lysozyme-like LysM domain 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
vWA-like TPR-like 11
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
PreATP-grasp domain ClpP/crotonase 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
UROD/MetE-like UROD/MetE-like 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Periplasmic binding protein-like II Histidine-containing phosphotransfer domain, HPT domain 11
Cysteine proteinases TPR-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Ribbon-helix-helix N-terminal domain of bifunctional PutA protein 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Duplicated hybrid motif Phosphohistidine domain 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
Phosphoenolpyruvate/pyruvate domain Nucleotide-diphospho-sugar transferases 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
LmbE-like Ricin B-like lectins 11
CheW-like CheY-like 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
Galactose-binding domain-like (Trans)glycosidases 11
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Ribonuclease H-like RuvA domain 2-like 11

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