SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Sphingopyxis alaskensis RB2256

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

581 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 273
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 1812
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 171
Thioredoxin-like GST C-terminal domain-like 161
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 145
Thiolase-like Thiolase-like 142
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 134
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 139
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 133
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 132
GroES-like NAD(P)-binding Rossmann-fold domains 112
Actin-like ATPase domain Actin-like ATPase domain 103
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 93
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 93
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 93
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 93
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 93
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 93
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 84
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 83
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 84
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 83
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 75
CheY-like P-loop containing nucleoside triphosphate hydrolases 73
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 71
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 73
CheY-like Homeodomain-like 73
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 65
Nucleotide cyclase EAL domain-like 65
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 61
CheY-like C-terminal effector domain of the bipartite response regulators 62
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 64
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 66
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
P-loop containing nucleoside triphosphate hydrolases Translation proteins 66
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 62
Homeodomain-like Ribonuclease H-like 61
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 52
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 55
HAD-like Calcium ATPase, transmembrane domain M 53
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 51
Calcium ATPase, transduction domain A HAD-like 53
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 51
PLP-binding barrel Alanine racemase C-terminal domain-like 52
PreATP-grasp domain Rudiment single hybrid motif 52
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 53
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 41
PYP-like sensor domain (PAS domain) Nucleotide cyclase 44
TPR-like TPR-like 44
DPP6 N-terminal domain-like alpha/beta-Hydrolases 42
Phospholipase D/nuclease Phospholipase D/nuclease 44
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 44
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 43
ParB/Sulfiredoxin KorB DNA-binding domain-like 41
Lysozyme-like beta-lactamase/transpeptidase-like 43
Ribosomal protein S5 domain 2-like P-loop containing nucleoside triphosphate hydrolases 44
Nucleic acid-binding proteins Nucleic acid-binding proteins 44
PurM N-terminal domain-like PurM C-terminal domain-like 42
Enolase N-terminal domain-like Enolase C-terminal domain-like 41
Ferritin-like HAD-like 31
Cupredoxins Cupredoxins 32
ClpP/crotonase ClpP/crotonase 33
Single hybrid motif CoA-dependent acyltransferases 32
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
PYP-like sensor domain (PAS domain) EAL domain-like 33
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Ferritin-like Calcium ATPase, transmembrane domain M 31
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 31
ACT-like ACT-like 33
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 31
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 31
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 32
Triger factor/SurA peptide-binding domain-like FKBP-like 33
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 32
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 32
P-loop containing nucleoside triphosphate hydrolases MOP-like 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 33
Chaperone J-domain HSP40/DnaJ peptide-binding domain 32
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 32
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 31
Translation proteins EF-G C-terminal domain-like 33
Ferritin-like Calcium ATPase, transduction domain A 31
cAMP-binding domain-like "Winged helix" DNA-binding domain 31
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 22
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
PreATP-grasp domain Single hybrid motif 21
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 22
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 22
Bacterial muramidases Lysozyme-like 21
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
Trypsin-like serine proteases PDZ domain-like 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 21
GroEL-intermediate domain like GroEL apical domain-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Alpha-L RNA-binding motif Pseudouridine synthase 22
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 22
Homodimeric domain of signal transducing histidine kinase CheY-like 22
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 22
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 22
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 21
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 22
P-loop containing nucleoside triphosphate hydrolases Glucocorticoid receptor-like (DNA-binding domain) 22
Multiheme cytochromes Multiheme cytochromes 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 21
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 22
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 22
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 22
PRTase-like PRTase-like 21
CBS-domain pair FAD-binding/transporter-associated domain-like 21
GroES-like GroES-like 21
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Nucleic acid-binding proteins RuvA domain 2-like 22
Macro domain-like Zn-dependent exopeptidases 22
Nucleotidyltransferase ACT-like 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 21
"Winged helix" DNA-binding domain Chorismate lyase-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Carbamate kinase-like ACT-like 22
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Glutathione synthetase ATP-binding domain-like Single hybrid motif 21
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 22
L30e-like alpha/beta knot 21
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 21
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 22
Aldolase AFP III-like domain 22
Aspartate/glutamate racemase Aspartate/glutamate racemase 21
S-adenosyl-L-methionine-dependent methyltransferases P-loop containing nucleoside triphosphate hydrolases 22
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
Rudiment single hybrid motif Single hybrid motif 21
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 21
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 21
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
GroEL equatorial domain-like GroEL-intermediate domain like 21
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
GroEL equatorial domain-like GroEL apical domain-like 21
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Class II aaRS and biotin synthetases Class II aaRS ABD-related 22
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
GAF domain-like Phosphohistidine domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 11
MetI-like MetI-like 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Ribokinase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Thioredoxin-like TPR-like 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
YlxR-like L30e-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 11
HCP-like Sporulation related repeat 11
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
CarD-like TRCF domain-like 11
Ribonuclease H-like HRDC-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
Galactose oxidase, central domain Galactose oxidase, central domain 11
YWTD domain Composite domain of metallo-dependent hydrolases 11
HRDC-like HRDC-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
PDZ domain-like ClpP/crotonase 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Trigger factor ribosome-binding domain FKBP-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Eukaryotic type KH-domain (KH-domain type I) P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
CBS-domain pair MgtE membrane domain-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Periplasmic binding protein-like II ACT-like 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 11
Serine metabolism enzymes domain ACT-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Nucleic acid-binding proteins BRCT domain 11
MFS general substrate transporter MFS general substrate transporter 11
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Nucleic acid-binding proteins PheT/TilS domain 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors CheY-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors NTF2-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Caspase-like HCP-like 11
Carbamate kinase-like PUA domain-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
HD-domain/PDEase-like TGS-like 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
TGS-like ThrRS/AlaRS common domain 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
HMA, heavy metal-associated domain HAD-like 11
MgtE N-terminal domain-like CBS-domain pair 11
YrdC/RibB RibA-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Pectin lyase-like Pectin lyase-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
DNA-glycosylase Nudix 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
PheT/TilS domain Putative DNA-binding domain 11
SMAD/FHA domain Multiheme cytochromes 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
OMPA-like OmpA-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
GspK insert domain-like GspK insert domain-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Methionine synthase domain Methionine synthase activation domain-like 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 11
HAD-like Glycerol-3-phosphate (1)-acyltransferase 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
GAF domain-like PYP-like sensor domain (PAS domain) 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Translation proteins PRC-barrel domain 11
Thioredoxin-like Peptide methionine sulfoxide reductase 11
Galactose mutarotase-like HAD-like 11
PDZ domain-like PDZ domain-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
JAB1/MPN domain "Winged helix" DNA-binding domain 11
ISP domain Bet v1-like 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Origin of replication-binding domain, RBD-like P-loop containing nucleoside triphosphate hydrolases 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
TPR-like P-loop containing nucleoside triphosphate hydrolases 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Cytochrome c Cytochrome c 11
FKBP-like FKBP-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
Dimeric alpha+beta barrel Dimeric alpha+beta barrel 11
FliG FliG 11
PUA domain-like alpha/beta knot 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
PHP14-like Phospholipase D/nuclease 11
RuvA domain 2-like JAB1/MPN domain 11
TGS-like Class II aaRS ABD-related 11
Pili subunits GspK insert domain-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
cAMP-binding domain-like 4Fe-4S ferredoxins 11
ACT-like Formyltransferase 11
lambda repressor-like DNA-binding domains Pheromone-binding domain of LuxR-like quorum-sensing transcription factors 11
DinB/YfiT-like putative metalloenzymes C-type lectin-like 11
Nucleotidyltransferase TGS-like 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
PA domain Zn-dependent exopeptidases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
PYP-like sensor domain (PAS domain) CheY-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
PPK N-terminal domain-like PHP14-like 11
Galactose-binding domain-like (Trans)glycosidases 11
HD-domain/PDEase-like Nucleotidyltransferase 11
Translation proteins ThrRS/AlaRS common domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Acid proteases Acid proteases 11
Nucleotide-binding domain Nucleotide-binding domain 11
ADC-like Cdc48 domain 2-like 11
TGS-like ACT-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Thioredoxin-like Thioredoxin-like 11
TrpR-like Ribonuclease H-like 11
CBS-domain pair PLP-dependent transferases 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Galactose mutarotase-like (Trans)glycosidases 11
YWTD domain Metallo-dependent hydrolases 11
PreATP-grasp domain PreATP-grasp domain 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
DNA clamp DNA clamp 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
YjeF N-terminal domain-like Ribokinase-like 11
RuvA domain 2-like BRCT domain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
YWTD domain DPP6 N-terminal domain-like 11
Hsp33 domain HSP33 redox switch-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
cAMP-binding domain-like cAMP-binding domain-like 11
lambda repressor-like DNA-binding domains RmlC-like cupins 11
DPP6 N-terminal domain-like Metallo-dependent hydrolases 11
Barwin-like endoglucanases Sporulation related repeat 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
PYP-like sensor domain (PAS domain) PilZ domain-like 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Nucleotidyltransferase Nucleotidyltransferase 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
"Winged helix" DNA-binding domain GAF domain-like 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
PIN domain-like DNA/RNA polymerases 11
Single hybrid motif Thiamin diphosphate-binding fold (THDP-binding) 11
FAD/NAD(P)-binding domain cAMP-binding domain-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Starch-binding domain-like Porins 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Formyltransferase YjbR-like 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Translation proteins Translation proteins 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 11
(Trans)glycosidases Glycosyl hydrolase domain 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
HD-domain/PDEase-like ACT-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Aldolase post-HMGL domain-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
AFP III-like domain Xylose isomerase-like 11
FAD-linked oxidoreductase ALDH-like 11
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Nucleic acid-binding proteins GAD domain-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Translation proteins Ribosomal protein S5 domain 2-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III TK C-terminal domain-like 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
PIN domain-like Ribonuclease H-like 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Inosine monophosphate dehydrogenase (IMPDH) Nitrite and sulphite reductase 4Fe-4S domain-like 11
Quinoprotein alcohol dehydrogenase-like Cytochrome c 11
Formyltransferase FMT C-terminal domain-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
CBS-domain pair Aldolase 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
PilZ domain-like lambda repressor-like DNA-binding domains 11
DPP6 N-terminal domain-like Composite domain of metallo-dependent hydrolases 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
"Winged helix" DNA-binding domain HRDC-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
EAL domain-like PilZ domain-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
TPR-like Sporulation related repeat 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
alpha/beta-Hydrolases FMN-binding split barrel 11
Carboxypeptidase regulatory domain-like Porins 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Aldolase Xylose isomerase-like 11
TGS-like Class II aaRS and biotin synthetases 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
HlyD-like secretion proteins HlyD-like secretion proteins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Ribosomal protein L6 Ribosomal protein L6 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Cdc48 domain 2-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleotide-diphospho-sugar transferases Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Ribonuclease H-like DNA/RNA polymerases 11
Galactose mutarotase-like Glycosyl hydrolase domain 11
Fe-S cluster assembly (FSCA) domain-like ISP domain 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 11
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 11
CoA-transferase family III (CaiB/BaiF) CoA-transferase family III (CaiB/BaiF) 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
alpha-helical ferredoxin ARM repeat 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
CBS-domain pair AFP III-like domain 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
Cadherin-like Soluble quinoprotein glucose dehydrogenase 11
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 11
Transmembrane di-heme cytochromes YceI-like 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Sm-like ribonucleoproteins Sm-like ribonucleoproteins 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
CheY-like Methylesterase CheB, C-terminal domain 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Class II aaRS ABD-related C-terminal domain of ProRS 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
Zinc beta-ribbon DNA primase core 11
CBS-domain pair Xylose isomerase-like 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
Class II aaRS and biotin synthetases C-terminal domain of ProRS 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Single hybrid motif TK C-terminal domain-like 11
alpha-helical ferredoxin Nucleotide-binding domain 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Nucleotide cyclase PilZ domain-like 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Sigma2 domain of RNA polymerase sigma factors NTF2-like 11
RNase III domain-like dsRNA-binding domain-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
YefM-like PYP-like sensor domain (PAS domain) 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
ADC-like P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Nucleotidylyl transferase tRNA-binding arm 11
TPR-like Clavaminate synthase-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
PilZ domain-like PilZ domain-like 11
Poly A polymerase C-terminal region-like ACT-like 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Six-hairpin glycosidases HAD-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Galactose mutarotase-like Six-hairpin glycosidases 11
Metallo-hydrolase/oxidoreductase SCP-like 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III Thiamin diphosphate-binding fold (THDP-binding) 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Nucleotidyltransferase substrate binding subunit/domain Poly A polymerase C-terminal region-like 11
GlcG-like GlcG-like 11

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