SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Psychromonas sp. CNPT3

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

604 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2816
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 191
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 145
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 138
Actin-like ATPase domain Actin-like ATPase domain 124
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 92
C-terminal effector domain of the bipartite response regulators CheY-like 82
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 84
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 75
P-loop containing nucleoside triphosphate hydrolases Translation proteins 76
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 73
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 65
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 64
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 64
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 63
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 64
PurM N-terminal domain-like PurM C-terminal domain-like 52
Ribosomal protein S5 domain 2-like P-loop containing nucleoside triphosphate hydrolases 54
Alpha-L RNA-binding motif Pseudouridine synthase 51
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 55
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 53
OMPA-like OmpA-like 52
Nucleic acid-binding proteins Nucleic acid-binding proteins 54
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 51
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 53
Thiolase-like Thiolase-like 52
CheY-like P-loop containing nucleoside triphosphate hydrolases 52
Translation proteins EF-G C-terminal domain-like 43
GroES-like NAD(P)-binding Rossmann-fold domains 42
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 42
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
P-loop containing nucleoside triphosphate hydrolases MOP-like 41
Homeodomain-like SIS domain 41
EF-G C-terminal domain-like EF-G C-terminal domain-like 43
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 41
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 41
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 42
MetI-like MetI-like 42
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 42
CheY-like Homeodomain-like 41
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 33
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 31
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Translation proteins SH3-like domain Nucleic acid-binding proteins 32
PK beta-barrel domain-like PK C-terminal domain-like 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 33
Calcium ATPase, transduction domain A HAD-like 33
PLP-binding barrel Alanine racemase C-terminal domain-like 32
Nucleic acid-binding proteins RuvA domain 2-like 33
Invasin/intimin cell-adhesion fragments Invasin/intimin cell-adhesion fragments 32
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 32
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 31
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 31
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 33
Nucleotide cyclase EAL domain-like 31
Thioredoxin-like GST C-terminal domain-like 31
CheW-like CheY-like 32
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Triger factor/SurA peptide-binding domain-like FKBP-like 33
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 31
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 31
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 32
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
PreATP-grasp domain Rudiment single hybrid motif 32
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 32
Nucleotidyltransferase HD-domain/PDEase-like 32
HD-domain/PDEase-like ACT-like 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Ribosomal protein S5 domain 2-like EF-G C-terminal domain-like 32
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 33
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 31
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
cAMP-binding domain-like "Winged helix" DNA-binding domain 31
Homodimeric domain of signal transducing histidine kinase CheY-like 33
Nucleotidyltransferase ACT-like 32
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 33
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 31
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 33
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 31
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 31
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 31
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 22
Ribonuclease H-like DNA/RNA polymerases 22
RmlC-like cupins Homeodomain-like 22
FAD/NAD(P)-binding domain Rhodanese/Cell cycle control phosphatase 21
HD-domain/PDEase-like TGS-like 21
Carbamate kinase-like ACT-like 22
Translation proteins ThrRS/AlaRS common domain 22
Calcium ATPase, transmembrane domain M HAD-like 22
Nucleotidyltransferase TGS-like 21
PYP-like sensor domain (PAS domain) Homeodomain-like 22
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
PYP-like sensor domain (PAS domain) Nucleotide cyclase 22
CheY-like Histidine-containing phosphotransfer domain, HPT domain 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 22
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 22
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
CheY-like TPR-like 21
Macro domain-like Zn-dependent exopeptidases 21
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Zinc beta-ribbon Zinc beta-ribbon 22
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
cAMP-binding domain-like CBS-domain pair 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
TPR-like TPR-like 22
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 22
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 22
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 21
Homeodomain-like Homeodomain-like 22
Phoshotransferase/anion transport protein PTS system IIB component-like 22
P-loop containing nucleoside triphosphate hydrolases Glucocorticoid receptor-like (DNA-binding domain) 22
CheY-like HD-domain/PDEase-like 21
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 22
Aspartate/glutamate racemase Aspartate/glutamate racemase 21
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 22
LysM domain LysM domain 22
L30e-like alpha/beta knot 21
FAD/NAD-linked reductases, dimerisation (C-terminal) domain Rhodanese/Cell cycle control phosphatase 21
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 22
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 22
HPr-like Phoshotransferase/anion transport protein 22
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Single hybrid motif CoA-dependent acyltransferases 22
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 22
TGS-like ACT-like 21
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 22
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 21
ClpP/crotonase ClpP/crotonase 22
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 22
Cytochrome c Cytochrome c 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Enolase N-terminal domain-like Enolase C-terminal domain-like 21
CBS-domain pair FAD-binding/transporter-associated domain-like 21
ACT-like NAD(P)-binding Rossmann-fold domains 22
HMA, heavy metal-associated domain HAD-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Translation proteins Ribosomal protein S5 domain 2-like 21
Thiolase-like FabD/lysophospholipase-like 22
2Fe-2S ferredoxin-like alpha-helical ferredoxin 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
ACT-like ACT-like 22
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 22
Lysozyme-like beta-lactamase/transpeptidase-like 22
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 11
"Winged helix" DNA-binding domain PLP-dependent transferases 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
"Winged helix" DNA-binding domain GAF domain-like 11
MOSC N-terminal domain-like PK beta-barrel domain-like 11
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Phoshotransferase/anion transport protein Phoshotransferase/anion transport protein 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
"Winged helix" DNA-binding domain C-terminal domain of transcriptional repressors 11
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
PreATP-grasp domain Single hybrid motif 11
Trigger factor ribosome-binding domain FKBP-like 11
Nucleotidylyl transferase tRNA-binding arm 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Tex N-terminal region-like Ribonuclease H-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Periplasmic binding protein-like II ACT-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
beta-Roll beta-Roll 11
Nucleotide-binding domain Nucleotide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
TGS-like Class II aaRS and biotin synthetases 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
Phospholipase D/nuclease Phospholipase D/nuclease 11
Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain 11
RuvA domain 2-like RuvA domain 2-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Barwin-like endoglucanases Sporulation related repeat 11
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
Phage tail proteins gp5 N-terminal domain-like 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Nqo1 FMN-binding domain-like alpha-helical ferredoxin 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 11
vWA-like beta-Roll 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
FliG FliG 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
P-loop containing nucleoside triphosphate hydrolases Acyl-CoA N-acyltransferases (Nat) 11
PUA domain-like alpha/beta knot 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Zinc beta-ribbon DNA primase core 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
HAMP domain-like CheY-like 11
Lysozyme-like LysM domain 11
Nucleotidyltransferase Nucleotidyltransferase 11
Galactose-binding domain-like (Trans)glycosidases 11
P-loop containing nucleoside triphosphate hydrolases Zinc beta-ribbon 11
Carbamate kinase-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
NosL/MerB-like NosL/MerB-like 11
ClpP/crotonase Glutathione synthetase ATP-binding domain-like 11
TGS-like ThrRS/AlaRS common domain 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
PIN domain-like DNA/RNA polymerases 11
Carbamate kinase-like PUA domain-like 11
PurS-like PurM N-terminal domain-like 11
CBS-domain pair MgtE membrane domain-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
MFS general substrate transporter S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleic acid-binding proteins PheT/TilS domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Thiolase-like NAD(P)-binding Rossmann-fold domains 11
4Fe-4S ferredoxins Radical SAM enzymes 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
CheY-like Methylesterase CheB, C-terminal domain 11
Nucleic acid-binding proteins BRCT domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
MgtE N-terminal domain-like CBS-domain pair 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
OmpA-like OmpA-like 11
PTS system IIB component-like PTS system IIB component-like 11
P-loop containing nucleoside triphosphate hydrolases TPR-like 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
"Winged helix" DNA-binding domain Chorismate lyase-like 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Metallo-hydrolase/oxidoreductase SCP-like 11
ACT-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
HisI-like all-alpha NTP pyrophosphatases 11
PurS-like FGAM synthase PurL, linker domain 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
YjgF-like YjgF-like 11
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 11
Ribonuclease H-like Nucleic acid-binding proteins 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
ALDH-like Dehydroquinate synthase-like 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
CarD-like TRCF domain-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
YajQ-like YajQ-like 11
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
ACP-like ACP-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
DNA clamp DNA clamp 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
ACT-like Formyltransferase 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Ribbon-helix-helix Replication modulator SeqA, C-terminal DNA-binding domain 11
PYP-like sensor domain (PAS domain) CheY-like 11
"Winged helix" DNA-binding domain C-terminal domain of arginine repressor 11
Pseudouridine synthase PUA domain-like 11
PDZ domain-like ClpP/crotonase 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
TGS-like Class II aaRS ABD-related 11
SIS domain CBS-domain pair 11
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
THUMP domain-like Rhodanese/Cell cycle control phosphatase 11
P-loop containing nucleoside triphosphate hydrolases Phospholipase D/nuclease 11
PheT/TilS domain Putative DNA-binding domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Translation proteins "Winged helix" DNA-binding domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Carbamate kinase-like NAD(P)-binding Rossmann-fold domains 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Rudiment single hybrid motif Single hybrid motif 11
NTF2-like Sec-C motif 11
Formyltransferase FMT C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
GspK insert domain-like GspK insert domain-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
LeuD/IlvD-like Aconitase iron-sulfur domain 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
CheY-like cAMP-binding domain-like 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
PDZ domain-like PDZ domain-like 11
Tex N-terminal region-like RuvA domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Putative DNA-binding domain Translation proteins 11
HAD-like Ribosomal protein S5 domain 2-like 11
Thiolase-like Thioesterase/thiol ester dehydrase-isomerase 11
Zn-dependent exopeptidases LysM domain 11
UDP-Glycosyltransferase/glycogen phosphorylase S-adenosyl-L-methionine-dependent methyltransferases 11
FAD-linked oxidoreductase ALDH-like 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Translation proteins Translation proteins 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Ribonuclease H-like HRDC-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
DNA-glycosylase Nudix 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Chorismate mutase II NAD(P)-binding Rossmann-fold domains 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
CheY-like CheC-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
vWA-like Quinoprotein alcohol dehydrogenase-like 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Periplasmic binding protein-like II GlnB-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
PurS-like PurM C-terminal domain-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
FKBP-like FKBP-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
RNase III domain-like dsRNA-binding domain-like 11
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
FabD/lysophospholipase-like ACP-like 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
TerB-like Chaperone J-domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
PK beta-barrel domain-like 2Fe-2S ferredoxin-like 11
beta-Galactosidase/glucuronidase domain Galactose mutarotase-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Ribonuclease H-like RuvA domain 2-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
MOSC N-terminal domain-like 2Fe-2S ferredoxin-like 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
Thiolase-like ACP-like 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
Phage tail proteins Phage fibre proteins 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Nudix Nudix 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 11
Class II aaRS and biotin synthetases GAD domain-like 11
Phase 1 flagellin Phase 1 flagellin 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Nqo5-like HydB/Nqo4-like 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
PurS-like Class I glutamine amidotransferase-like 11
THUMP domain-like Adenine nucleotide alpha hydrolases-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
alpha-helical ferredoxin Nucleotide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases PGBD-like 11
ClpP/crotonase Single hybrid motif 11
Trypsin-like serine proteases PDZ domain-like 11
Globin-like Riboflavin synthase domain-like 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 11
CheC-like Surface presentation of antigens (SPOA) 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Invasin/intimin cell-adhesion fragments RCC1/BLIP-II 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
ClpP/crotonase PreATP-grasp domain 11
HesB-like domain Fe-S cluster assembly (FSCA) domain-like 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain 11
Pili subunits GspK insert domain-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
ClpP/crotonase Rudiment single hybrid motif 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
WD40 repeat-like MetI-like 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
DNA primase core DNA primase DnaG, C-terminal domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
cAMP-binding domain-like Homodimeric domain of signal transducing histidine kinase 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
PreATP-grasp domain Methylglyoxal synthase-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
DeoB insert domain-like Alkaline phosphatase-like 11
HIT-like HIT-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
ACP-like NAD(P)-binding Rossmann-fold domains 11
Ribokinase-like Nucleotidylyl transferase 11
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
Aldolase AFP III-like domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Nitrous oxide reductase, N-terminal domain Multiheme cytochromes 11
PreATP-grasp domain PreATP-grasp domain 11
Class II aaRS and biotin synthetases Translation proteins 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
FMN-binding split barrel UbiD C-terminal domain-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
PIN domain-like Ribonuclease H-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
HRDC-like HRDC-like 11
Single hybrid motif Single hybrid motif 11
RuvA domain 2-like BRCT domain 11
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
CheY-like CheY-like 11
Translation proteins PRC-barrel domain 11
PilZ domain-like PilZ domain-like 11
Periplasmic binding protein-like II Lysozyme-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Hsp33 domain HSP33 redox switch-like 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
DAK1/DegV-like DhaL-like 11
Galactose-binding domain-like Galactose mutarotase-like 11
Bacterial muramidases Lysozyme-like 11
Ribulose-phoshate binding barrel Ribulose-phoshate binding barrel 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Nucleic acid-binding proteins GAD domain-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
Ribosomal protein L6 Ribosomal protein L6 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
Ribokinase-like Thiamin phosphate synthase 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
TPR-like Nucleotide cyclase 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 11
gp5 N-terminal domain-like Phage fibre proteins 11
GroEL-intermediate domain like GroEL apical domain-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Phage tail proteins Phage tail proteins 11
Adenine nucleotide alpha hydrolases-like Rhodanese/Cell cycle control phosphatase 11
Class II aaRS and biotin synthetases SufE/NifU 11
Galactose-binding domain-like His-Me finger endonucleases 11
(Trans)glycosidases Galactose mutarotase-like 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Zn-binding ribosomal proteins 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Tetrahydrobiopterin biosynthesis enzymes-like Tetrahydrobiopterin biosynthesis enzymes-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
vWA-like TPR-like 11
Enolase C-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
cAMP-binding domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Chorismate mutase II 6-phosphogluconate dehydrogenase C-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
GroES-like GroES-like 11

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