SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Klebsiella oxytoca E718

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

868 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 912
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 4814
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 331
Homeodomain-like Homeodomain-like 318
Actin-like ATPase domain Actin-like ATPase domain 277
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 245
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 2411
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 226
GroES-like NAD(P)-binding Rossmann-fold domains 202
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 201
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 181
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 176
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 173
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 165
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 161
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 162
P-loop containing nucleoside triphosphate hydrolases MOP-like 151
Enolase N-terminal domain-like Enolase C-terminal domain-like 151
CheY-like C-terminal effector domain of the bipartite response regulators 151
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 144
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 145
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 133
PapD-like Periplasmic chaperone C-domain 132
Thioredoxin-like GST C-terminal domain-like 131
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 133
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 133
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 133
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 138
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 133
"Winged helix" DNA-binding domain Chorismate lyase-like 121
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 123
Glutathione synthetase ATP-binding domain-like PreATP-grasp domain 126
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 124
Thiolase-like Thiolase-like 111
"Winged helix" DNA-binding domain PLP-dependent transferases 111
Homeodomain-like SIS domain 111
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 112
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 103
Regulatory protein AraC Homeodomain-like 103
RmlC-like cupins Homeodomain-like 92
P-loop containing nucleoside triphosphate hydrolases Translation proteins 97
(Trans)glycosidases Glycosyl hydrolase domain 98
"Winged helix" DNA-binding domain GAF domain-like 81
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 81
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 81
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 85
Resolvase-like Homeodomain-like 81
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 75
MetI-like MetI-like 73
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 75
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 71
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 65
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 65
PreATP-grasp domain Rudiment single hybrid motif 62
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 62
Nucleotide cyclase EAL domain-like 62
ACT-like ACT-like 65
HAD-like Calcium ATPase, transmembrane domain M 63
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 63
Calcium ATPase, transduction domain A HAD-like 63
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 63
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 63
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 63
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
lambda repressor-like DNA-binding domains RmlC-like cupins 51
E set domains (Trans)glycosidases 54
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 53
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 54
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 52
Phospholipase D/nuclease Phospholipase D/nuclease 53
Nucleic acid-binding proteins Nucleic acid-binding proteins 54
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 53
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 52
CBS-domain pair FAD-binding/transporter-associated domain-like 51
PTS-regulatory domain, PRD PTS-regulatory domain, PRD 53
PurM N-terminal domain-like PurM C-terminal domain-like 52
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 52
Alpha-L RNA-binding motif Pseudouridine synthase 51
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 51
MFS general substrate transporter MFS general substrate transporter 52
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 52
"Winged helix" DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 55
HlyD-like secretion proteins HlyD-like secretion proteins 53
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 51
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 53
RuvA domain 2-like Nucleic acid-binding proteins 44
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 41
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 41
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 42
Translation proteins EF-G C-terminal domain-like 43
PLP-binding barrel Alanine racemase C-terminal domain-like 42
P-loop containing nucleoside triphosphate hydrolases PTS-regulatory domain, PRD 43
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 41
Aldolase post-HMGL domain-like 43
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 42
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 42
Phage tail proteins Phage tail proteins 43
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 42
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 42
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 44
TrkA C-terminal domain-like TrkA C-terminal domain-like 42
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
Galactose mutarotase-like (Trans)glycosidases 43
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 43
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 41
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 41
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 42
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 41
EF-G C-terminal domain-like EF-G C-terminal domain-like 43
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 42
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 43
Phage tail proteins gp5 N-terminal domain-like 43
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 44
LeuD/IlvD-like Aconitase iron-sulfur domain 42
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 42
P-loop containing nucleoside triphosphate hydrolases PTS system fructose IIA component-like 43
GAF domain-like Homeodomain-like 42
PTS system fructose IIA component-like PTS-regulatory domain, PRD 43
E set domains alpha/beta-Hydrolases 32
TPR-like TPR-like 33
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 33
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 33
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 33
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 31
PDZ domain-like PDZ domain-like 33
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
Beta-D-glucan exohydrolase, C-terminal domain (Trans)glycosidases 32
P-loop containing nucleoside triphosphate hydrolases C-terminal effector domain of the bipartite response regulators 32
Glucose permease domain IIB Duplicated hybrid motif 32
FMN-binding split barrel UbiD C-terminal domain-like 32
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 33
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 31
H-NS histone-like proteins H-NS histone-like proteins 31
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 33
Homeodomain-like Ribonuclease H-like 32
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 33
Nucleic acid-binding proteins Translation proteins SH3-like domain 32
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 31
HD-domain/PDEase-like ACT-like 32
Aspartate/glutamate racemase Aspartate/glutamate racemase 31
Single hybrid motif CoA-dependent acyltransferases 33
Homeodomain-like Probable bacterial effector-binding domain 32
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 33
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
Sporulation response regulatory protein Spo0B ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 33
PYP-like sensor domain (PAS domain) Homeodomain-like 32
Lysozyme-like beta-lactamase/transpeptidase-like 32
CoA-dependent acyltransferases ACP-like 33
Phoshotransferase/anion transport protein HPr-like 33
Cyclophilin-like PH0987 N-terminal domain-like 32
Triger factor/SurA peptide-binding domain-like FKBP-like 33
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 32
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 33
(Trans)glycosidases Galactose-binding domain-like 32
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 33
Homodimeric domain of signal transducing histidine kinase CheY-like 33
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 33
"Winged helix" DNA-binding domain Actin-like ATPase domain 31
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
Class I glutamine amidotransferase-like Homeodomain-like 31
Sensory domain-like Sporulation response regulatory protein Spo0B 31
PYP-like sensor domain (PAS domain) Sporulation response regulatory protein Spo0B 31
GAF domain-like Nucleotide cyclase 32
Ribosomal protein S5 domain 2-like EF-G C-terminal domain-like 32
cAMP-binding domain-like "Winged helix" DNA-binding domain 31
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 32
E set domains Glycosyl hydrolase domain 33
Nucleotidyltransferase HD-domain/PDEase-like 32
Sensory domain-like PYP-like sensor domain (PAS domain) 31
Nucleotidyltransferase ACT-like 32
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
CoA-dependent acyltransferases CoA-dependent acyltransferases 33
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Trypsin-like serine proteases PDZ domain-like 33
P-loop containing nucleoside triphosphate hydrolases ACT-like 32
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 33
CheY-like P-loop containing nucleoside triphosphate hydrolases 31
CheY-like Homeodomain-like 31
FMN-linked oxidoreductases Nucleotide-binding domain 22
Nqo1 FMN-binding domain-like alpha-helical ferredoxin 22
post-HMGL domain-like Single hybrid motif 21
GroEL-intermediate domain like GroEL apical domain-like 21
PEP carboxykinase N-terminal domain PEP carboxykinase-like 21
"Winged helix" DNA-binding domain PTS-regulatory domain, PRD 22
2Fe-2S ferredoxin-like alpha-helical ferredoxin 21
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 22
Aldolase Single hybrid motif 21
HPr-like Phosphohistidine domain 22
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Thiamin diphosphate-binding fold (THDP-binding) 4Fe-4S ferredoxins 21
Nucleotidyltransferase TGS-like 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
P-loop containing nucleoside triphosphate hydrolases Glucocorticoid receptor-like (DNA-binding domain) 22
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 21
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
HD-domain/PDEase-like HD-domain/PDEase-like 21
CheY-like Histidine-containing phosphotransfer domain, HPT domain 22
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
Translation proteins Ribosomal protein S5 domain 2-like 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
TGS-like ACT-like 21
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
Translation proteins ThrRS/AlaRS common domain 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
Periplasmic binding protein-like II Lysozyme-like 22
ParB/Sulfiredoxin KorB DNA-binding domain-like 21
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 22
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 22
Aconitase B, N-terminal domain LeuD/IlvD-like 21
Chitinase insertion domain Carbohydrate binding domain 21
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 22
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 22
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 22
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 22
ClpP/crotonase ClpP/crotonase 22
Acetyl-CoA synthetase-like ACP-like 22
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 21
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 22
gp5 N-terminal domain-like Phage fibre proteins 22
E set domains E set domains 22
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
HMA, heavy metal-associated domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 22
TPR-like C-terminal effector domain of the bipartite response regulators 21
HMA, heavy metal-associated domain HAD-like 22
ACP-like S-adenosyl-L-methionine-dependent methyltransferases 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 21
SacY-like RNA-binding domain PTS-regulatory domain, PRD 21
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 21
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 22
Folate-binding domain Aminomethyltransferase beta-barrel domain 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
4Fe-4S ferredoxins Nucleotide-binding domain 21
GroEL equatorial domain-like GroEL apical domain-like 21
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 21
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 21
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 22
Phage tail proteins Phage fibre proteins 22
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 21
CoA-dependent acyltransferases S-adenosyl-L-methionine-dependent methyltransferases 22
Nqo5-like HydB/Nqo4-like 21
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 22
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 21
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
HD-domain/PDEase-like TGS-like 21
GspK insert domain-like GspK insert domain-like 21
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 22
(Trans)glycosidases Chitinase insertion domain 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Galactose mutarotase-like E set domains 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
CcmK-like CcmK-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Carbamate kinase-like NAD(P)-binding Rossmann-fold domains 22
Galactose mutarotase-like Glycosyl hydrolase domain 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 22
DsbC/DsbG N-terminal domain-like Thioredoxin-like 21
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
ACP-like alpha/beta-Hydrolases 22
(Trans)glycosidases Class I glutamine amidotransferase-like 21
HMA, heavy metal-associated domain FAD/NAD(P)-binding domain 22
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 21
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
beta-Galactosidase/glucuronidase domain Galactose mutarotase-like 21
Nucleotide-diphospho-sugar transferases PilZ domain-like 22
L30e-like alpha/beta knot 22
TK C-terminal domain-like 4Fe-4S ferredoxins 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Cupredoxins Cupredoxins 21
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 21
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 21
beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain 21
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 4Fe-4S ferredoxins 21
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
CoA-dependent acyltransferases alpha/beta-Hydrolases 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
CheY-like CheY-like 22
AhpD-like AhpD-like 21
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 21
Galactose-binding domain-like Galactose mutarotase-like 21
(Trans)glycosidases Carbohydrate binding domain 21
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 22
PK beta-barrel domain-like PK C-terminal domain-like 21
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 21
P-loop containing nucleoside triphosphate hydrolases TPR-like 21
GroEL equatorial domain-like GroEL-intermediate domain like 21
MalF N-terminal region-like MetI-like 22
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 21
FucI/AraA N-terminal and middle domains FucI/AraA C-terminal domain-like 21
ACP-like ACP-like 22
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
CBS-domain pair MgtE membrane domain-like 22
Pili subunits GspK insert domain-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 22
ACT-like NAD(P)-binding Rossmann-fold domains 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 21
Siroheme synthase middle domains-like Tetrapyrrole methylase 21
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 21
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 21
Actin-like ATPase domain HD-domain/PDEase-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
alpha-helical ferredoxin Nucleotide-binding domain 22
Tropomyosin Porins 21
MetI-like P-loop containing nucleoside triphosphate hydrolases 21
CoA-dependent acyltransferases Acetyl-CoA synthetase-like 22
Acylphosphatase/BLUF domain-like EAL domain-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 21
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 21
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
Carbamate kinase-like ACT-like 22
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 22
Formyltransferase FMT C-terminal domain-like 22
Carbamate kinase-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 22
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
THUMP domain-like Rhodanese/Cell cycle control phosphatase 11
Tex N-terminal region-like Ribonuclease H-like 11
Copper amine oxidase, domain N Amine oxidase N-terminal region 11
Nudix "Winged helix" DNA-binding domain 11
SIS domain CBS-domain pair 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes CBS-domain pair 11
PYP-like sensor domain (PAS domain) CheY-like 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Pseudouridine synthase PUA domain-like 11
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 11
Periplasmic binding protein-like II ACT-like 11
HAD-like Ribosomal protein S5 domain 2-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain 11
(Phosphotyrosine protein) phosphatases II Autotransporter 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Glycerol-3-phosphate (1)-acyltransferase Acyl-CoA N-acyltransferases (Nat) 11
Thiolase-like alpha/beta-Hydrolases 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase alpha/beta-Hydrolases 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
FMN-linked oxidoreductases alpha-helical ferredoxin 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Zinc beta-ribbon Zinc beta-ribbon 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
YajQ-like YajQ-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Nitrous oxide reductase, N-terminal domain Nitrous oxide reductase, N-terminal domain 11
NAD(P)-binding Rossmann-fold domains CoA-dependent acyltransferases 11
PrpR receptor domain-like Homeodomain-like 11
Translation proteins "Winged helix" DNA-binding domain 11
PurS-like PurM C-terminal domain-like 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
RuvA domain 2-like BRCT domain 11
Chorismate mutase II 6-phosphogluconate dehydrogenase C-terminal domain-like 11
PreATP-grasp domain Cyclophilin-like 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
CO dehydrogenase molybdoprotein N-domain-like CO dehydrogenase flavoprotein C-terminal domain-like 11
RNase III domain-like dsRNA-binding domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
PrpR receptor domain-like P-loop containing nucleoside triphosphate hydrolases 11
FAD/NAD(P)-binding domain ISP domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
"Winged helix" DNA-binding domain Iron-dependent repressor protein, dimerization domain 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
GAF domain-like GAF domain-like 11
Globin-like Nucleotide cyclase 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Class II aaRS and biotin synthetases Translation proteins 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
FabD/lysophospholipase-like alpha/beta-Hydrolases 11
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
DNA-glycosylase Nudix 11
Acetyl-CoA synthetase-like alpha/beta-Hydrolases 11
GIY-YIG endonuclease RuvA domain 2-like 11
HAMP domain-like Nucleotide cyclase 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
P-loop containing nucleoside triphosphate hydrolases Acyl-CoA N-acyltransferases (Nat) 11
Glutathione synthetase ATP-binding domain-like Acyl-CoA N-acyltransferases (Nat) 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
LysM domain L,D-transpeptidase catalytic domain-like 11
PHP14-like Phospholipase D/nuclease 11
PGBD-like L,D-transpeptidase catalytic domain-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
HPr-like Phosphoenolpyruvate/pyruvate domain 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
Class II aaRS and biotin synthetases SufE/NifU 11
Fibronectin type III Galactose-binding domain-like 11
Nitrite and sulphite reductase 4Fe-4S domain-like ISP domain 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
FKBP-like FKBP-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 11
Chorismate mutase II NAD(P)-binding Rossmann-fold domains 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
ClpP/crotonase TPR-like 11
4Fe-4S ferredoxins Radical SAM enzymes 11
Ribbon-helix-helix ALDH-like 11
Class I glutamine amidotransferase-like Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
S-adenosyl-L-methionine-dependent methyltransferases alpha/beta-Hydrolases 11
Nucleic acid-binding proteins BRCT domain 11
Homeodomain-like Periplasmic binding protein-like II 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Carbamate kinase-like PUA domain-like 11
MgtE N-terminal domain-like CBS-domain pair 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Thioredoxin-like Thioredoxin-like 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
FabD/lysophospholipase-like ACP-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
MFS general substrate transporter PilZ domain-like 11
Radical SAM enzymes Nitrogenase accessory factor-like 11
PreATP-grasp domain PH0987 N-terminal domain-like 11
Lysozyme-like PKD domain 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Zinc beta-ribbon "Winged helix" DNA-binding domain 11
HAMP domain-like GAF domain-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
CheY-like Ornithine decarboxylase C-terminal domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Macro domain-like Zn-dependent exopeptidases 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Glutathione synthetase ATP-binding domain-like PH0987 N-terminal domain-like 11
Nucleotidylyl transferase tRNA-binding arm 11
GroES-like GroES-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
TGS-like Class II aaRS ABD-related 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
MOSC N-terminal domain-like PK beta-barrel domain-like 11
Bacterial adhesins Bacterial adhesins 11
Lysozyme-like LysM domain 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
TATA-box binding protein-like DNA-glycosylase 11
IHF-like DNA-binding proteins TraM-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Cytochrome c Cytochrome c 11
Thioredoxin-like TPR-like 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
PTS system fructose IIA component-like PTS IIb component 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
"Winged helix" DNA-binding domain Phoshotransferase/anion transport protein 11
PTS system IIB component-like Phoshotransferase/anion transport protein 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Cysteine proteinases PreATP-grasp domain 11
YgfB-like Sec-C motif 11
Cyclophilin-like Single hybrid motif 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Ribonuclease H-like RuvA domain 2-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Homeodomain-like NagB/RpiA/CoA transferase-like 11
Copper amine oxidase, domain N Amine oxidase catalytic domain 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Acyl-CoA N-acyltransferases (Nat) Nucleotidylyl transferase 11
Zinc beta-ribbon DNA primase core 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
CheY-like "Winged helix" DNA-binding domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
PYP-like sensor domain (PAS domain) EAL domain-like 11
Formyltransferase NAD(P)-binding Rossmann-fold domains 11
(Trans)glycosidases Fibronectin type III 11
Methionine synthase domain Methionine synthase activation domain-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
PH0987 N-terminal domain-like Single hybrid motif 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain "Winged helix" DNA-binding domain 11
Pectin lyase-like Pectin lyase-like 11
Cytidine deaminase-like Cytidine deaminase-like 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
UDP-Glycosyltransferase/glycogen phosphorylase Nucleotide-diphospho-sugar transferases 11
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 11
Class II aaRS and biotin synthetases GAD domain-like 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
"Winged helix" DNA-binding domain C-terminal domain of arginine repressor 11
ACT-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
Starch-binding domain-like Glycosyl hydrolase domain 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
CarD-like TRCF domain-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
HIT-like HIT-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Starch-binding domain-like E set domains 11
Acyl-CoA N-acyltransferases (Nat) Thioesterase/thiol ester dehydrase-isomerase 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 11
UROD/MetE-like UROD/MetE-like 11
Nucleic acid-binding proteins PheT/TilS domain 11
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
RuvA domain 2-like RuvA domain 2-like 11
NAD(P)-binding Rossmann-fold domains ACP-like 11
Hsp33 domain HSP33 redox switch-like 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
Chorismate mutase II Periplasmic binding protein-like II 11
DAK1/DegV-like DhaL-like 11
"Winged helix" DNA-binding domain C-terminal domain of transcriptional repressors 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
lambda repressor-like DNA-binding domains Nucleotidylyl transferase 11
Nitrite/Sulfite reductase N-terminal domain-like ISP domain 11
4Fe-4S ferredoxins Iron-sulfur subunit of formate dehydrogenase N, transmembrane anchor 11
PLP-dependent transferases PLP-dependent transferases 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Zn-binding ribosomal proteins 11
PTS-regulatory domain, PRD PTS system IIB component-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phoshotransferase/anion transport protein 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 11
"Winged helix" DNA-binding domain MukF C-terminal domain-like 11
GAF domain-like EAL domain-like 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
"Winged helix" DNA-binding domain PTS system fructose IIA component-like 11
PTS system fructose IIA component-like Phosphohistidine domain 11
LysM domain Duplicated hybrid motif 11
FAD-linked oxidoreductase ALDH-like 11
Nucleotidylyl transferase P-loop containing nucleoside triphosphate hydrolases 11
PreATP-grasp domain Methylglyoxal synthase-like 11
DNA primase core DNA primase DnaG, C-terminal domain 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases FAD/NAD(P)-binding domain 11
Isochorismatase-like hydrolases ACP-like 11
FMN-linked oxidoreductases Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 11
DeoB insert domain-like Alkaline phosphatase-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Cobalamin adenosyltransferase-like GlcG-like 11
Barwin-like endoglucanases Sporulation related repeat 11
PYP-like sensor domain (PAS domain) Nucleotide cyclase 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Activating enzymes of the ubiquitin-like proteins JAB1/MPN domain 11
P-loop containing nucleoside triphosphate hydrolases beta-sandwich domain of Sec23/24 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 11
ACT-like Formyltransferase 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Glycerol-3-phosphate (1)-acyltransferase Acetyl-CoA synthetase-like 11
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
PTS system fructose IIA component-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Phosphohistidine domain Phoshotransferase/anion transport protein 11
Band 7/SPFH domain Band 7/SPFH domain 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Nudix Nudix 11
ALDH-like Acetyl-CoA synthetase-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
ALDH-like Thioesterase/thiol ester dehydrase-isomerase 11
Phosphoenolpyruvate/pyruvate domain Phoshotransferase/anion transport protein 11
Pentapeptide repeat-like Pentapeptide repeat-like 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
YdgH-like YdgH-like 11
Galactose mutarotase-like Putative glucosidase YicI, C-terminal domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Tex N-terminal region-like RuvA domain 2-like 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 11
(Trans)glycosidases Putative glucosidase YicI, C-terminal domain 11
ALDH-like Dehydroquinate synthase-like 11
PPK N-terminal domain-like PHP14-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
PIN domain-like DNA/RNA polymerases 11
Thiolase-like CoA-dependent acyltransferases 11
SufE/NifU Fe-S cluster assembly (FSCA) domain-like 11
TrkA C-terminal domain-like FAD-binding/transporter-associated domain-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Swiveling domain of dehydratase reactivase alpha subunit Actin-like ATPase domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Amine oxidase N-terminal region Amine oxidase N-terminal region 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
HRDC-like HRDC-like 11
Ribonuclease H-like HRDC-like 11
ABC transporter involved in vitamin B12 uptake, BtuC ABC transporter involved in vitamin B12 uptake, BtuC 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Rudiment single hybrid motif PH0987 N-terminal domain-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Molybdenum cofactor biosynthesis proteins CinA-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
PDZ domain-like ClpP/crotonase 11
4Fe-4S ferredoxins Respiratory nitrate reductase 1 gamma chain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Phoshotransferase/anion transport protein Phoshotransferase/anion transport protein 11
Heme-dependent catalase-like Class I glutamine amidotransferase-like 11
CheY-like PLP-dependent transferases 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
PurS-like Class I glutamine amidotransferase-like 11
Periplasmic binding protein-like II GlnB-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
ACT-like PYP-like sensor domain (PAS domain) 11
Amine oxidase N-terminal region Amine oxidase catalytic domain 11
HCP-like HCP-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Putative DNA-binding domain Translation proteins 11
PTS system IIB component-like PTS system IIB component-like 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
Ribbon-helix-helix FAD-linked oxidoreductase 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
Glutathione synthetase ATP-binding domain-like Cyclophilin-like 11
PreATP-grasp domain PreATP-grasp domain 11
Fic-like "Winged helix" DNA-binding domain 11
Periplasmic binding protein-like I Homeodomain-like 11
HisI-like all-alpha NTP pyrophosphatases 11
Acetyl-CoA synthetase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
PIN domain-like Ribonuclease H-like 11
TGS-like ThrRS/AlaRS common domain 11
TGS-like Class II aaRS and biotin synthetases 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
NAD(P)-binding Rossmann-fold domains Bet v1-like 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
MOP-like MOP-like 11
4Fe-4S ferredoxins ADC-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
lambda repressor-like DNA-binding domains P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Periplasmic binding protein-like II 11
Nqo1 middle domain-like alpha-helical ferredoxin 11
Translation proteins PRC-barrel domain 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
MOSC N-terminal domain-like 2Fe-2S ferredoxin-like 11
Metallo-hydrolase/oxidoreductase Rubredoxin-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Bacterial muramidases Lysozyme-like 11
PheT/TilS domain Putative DNA-binding domain 11
DNA clamp DNA clamp 11
"Winged helix" DNA-binding domain MOP-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Flavoproteins Rubredoxin-like 11
CRISPR-associated protein CRISPR-associated protein 11
Globin-like Riboflavin synthase domain-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
HesB-like domain Fe-S cluster assembly (FSCA) domain-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
Thiolase-like FabD/lysophospholipase-like 11
Adenine nucleotide alpha hydrolases-like Rhodanese/Cell cycle control phosphatase 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
PUA domain-like alpha/beta knot 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
PreATP-grasp domain Single hybrid motif 11
FabD/lysophospholipase-like S-adenosyl-L-methionine-dependent methyltransferases 11
"Winged helix" DNA-binding domain Ribokinase-like 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
FabD/lysophospholipase-like CoA-dependent acyltransferases 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Ribbon-helix-helix ACT-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Chorismate mutase II ACT-like 11
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 11
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 11
Starch-binding domain-like (Trans)glycosidases 11
Thiolase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
alpha-helical ferredoxin alpha-helical ferredoxin 11
Ribbon-helix-helix Replication modulator SeqA, C-terminal DNA-binding domain 11
Molybdenum cofactor-binding domain CO dehydrogenase flavoprotein C-terminal domain-like 11
Ribbon-helix-helix N-terminal domain of bifunctional PutA protein 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Cysteine proteinases Glutathione synthetase ATP-binding domain-like 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Rudiment single hybrid motif Single hybrid motif 11
RuvA domain 2-like JAB1/MPN domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
PurS-like FGAM synthase PurL, linker domain 11
YjeF N-terminal domain-like Ribokinase-like 11
Rudiment single hybrid motif Cyclophilin-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Origin of replication-binding domain, RBD-like P-loop containing nucleoside triphosphate hydrolases 11
Glycosyl hydrolase domain Putative glucosidase YicI, C-terminal domain 11
PTS-regulatory domain, PRD Phoshotransferase/anion transport protein 11
ACT-like Homeodomain-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase CoA-dependent acyltransferases 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase S-adenosyl-L-methionine-dependent methyltransferases 11
Ribonuclease H-like DNA/RNA polymerases 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
CbiG N-terminal domain-like CobE/GbiG C-terminal domain-like 11
Homeodomain-like (Trans)glycosidases 11
OMPA-like OmpA-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Metallo-hydrolase/oxidoreductase Flavoproteins 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
Thiolase-like ACP-like 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Cyclophilin-like Cyclophilin-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Metallo-hydrolase/oxidoreductase SCP-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
Flavoproteins Riboflavin synthase domain-like 11
NAD(P)-binding Rossmann-fold domains alpha/beta-Hydrolases 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
FMT C-terminal domain-like NAD(P)-binding Rossmann-fold domains 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
PK beta-barrel domain-like 2Fe-2S ferredoxin-like 11
Ribokinase-like Nucleotidylyl transferase 11
ISP domain Bet v1-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Homeodomain-like Glycosyl hydrolase domain 11
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Translation proteins Translation proteins 11
Pectin lyase-like Autotransporter 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
PurS-like PurM N-terminal domain-like 11
LysM domain LysM domain 11
HAMP domain-like CheY-like 11
Zinc beta-ribbon P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
THUMP domain-like Adenine nucleotide alpha hydrolases-like 11
DNA methylase specificity domain DNA methylase specificity domain 11
Thiolase-like NAD(P)-binding Rossmann-fold domains 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 11
PTS system fructose IIA component-like HPr-like 11
Molybdenum cofactor-binding domain FAD-binding/transporter-associated domain-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
Fibronectin type III Pectin lyase-like 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
CO dehydrogenase molybdoprotein N-domain-like FAD-binding/transporter-associated domain-like 11
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 11
MFS general substrate transporter Proline/betaine transporter ProP, C-terminal cytoplasmic domain 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
MFS general substrate transporter Nucleotide-diphospho-sugar transferases 11
GAF domain-like Phosphohistidine domain 11
Single hybrid motif Single hybrid motif 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
NTF2-like Sec-C motif 11
2Fe-2S ferredoxin-like ADC-like 11
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 11
Class I glutamine amidotransferase-like Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Ribosomal protein L6 Ribosomal protein L6 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
PFL-like glycyl radical enzymes PFL-like glycyl radical enzymes 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
Ribulose-phoshate binding barrel Ribulose-phoshate binding barrel 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11

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