SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Spiribacter sp. UAH-SP71

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

531 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2413
Actin-like ATPase domain Actin-like ATPase domain 113
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 101
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 83
P-loop containing nucleoside triphosphate hydrolases MOP-like 81
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 88
PYP-like sensor domain (PAS domain) Nucleotide cyclase 88
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 82
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 74
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 72
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 61
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
GroES-like NAD(P)-binding Rossmann-fold domains 62
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Nucleotide cyclase EAL domain-like 66
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 63
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 63
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 62
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 63
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 64
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 54
P-loop containing nucleoside triphosphate hydrolases Translation proteins 55
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 55
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 43
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 44
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 44
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
Cytochrome c Cytochrome c 42
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 42
Triger factor/SurA peptide-binding domain-like FKBP-like 44
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 43
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 43
cAMP-binding domain-like "Winged helix" DNA-binding domain 41
Calcium ATPase, transduction domain A HAD-like 44
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 43
Thioredoxin-like GST C-terminal domain-like 41
PurM N-terminal domain-like PurM C-terminal domain-like 43
HAD-like Calcium ATPase, transmembrane domain M 44
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 42
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 44
Trypsin-like serine proteases PDZ domain-like 32
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 32
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 33
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
Translation proteins EF-G C-terminal domain-like 33
ACT-like ACT-like 32
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 32
PYP-like sensor domain (PAS domain) EAL domain-like 33
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 31
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 32
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 31
HD-domain/PDEase-like ACT-like 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Enolase N-terminal domain-like Enolase C-terminal domain-like 31
PDZ domain-like PDZ domain-like 32
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 33
PreATP-grasp domain Rudiment single hybrid motif 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 33
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 31
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 33
Nucleotidyltransferase ACT-like 32
CheY-like C-terminal effector domain of the bipartite response regulators 31
Alpha-L RNA-binding motif Pseudouridine synthase 31
Nucleotidyltransferase HD-domain/PDEase-like 32
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 32
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
MetI-like MetI-like 32
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 31
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
CheY-like Homeodomain-like 31
Thiolase-like Thiolase-like 31
CheY-like P-loop containing nucleoside triphosphate hydrolases 31
NAD(P)-binding Rossmann-fold domains ACT-like 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
PDZ domain-like ClpP/crotonase 21
Lysozyme-like LysM domain 22
CBS-domain pair Nucleotidyltransferase 21
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
HMA, heavy metal-associated domain HAD-like 22
CBS-domain pair FAD-binding/transporter-associated domain-like 21
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 22
TrkA C-terminal domain-like TrkA C-terminal domain-like 22
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 21
Phospholipase D/nuclease Phospholipase D/nuclease 22
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
LysM domain LysM domain 22
Homodimeric domain of signal transducing histidine kinase CheY-like 22
Nucleic acid-binding proteins RuvA domain 2-like 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
CheY-like Nucleotide cyclase 22
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
HD-domain/PDEase-like TGS-like 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 22
Nucleotidyltransferase TGS-like 21
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
TGS-like ACT-like 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 22
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 22
Succinyl-CoA synthetase domains Glutathione synthetase ATP-binding domain-like 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 21
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 22
cAMP-binding domain-like Nucleotidyltransferase 21
GAF domain-like Nucleotide cyclase 22
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 22
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 21
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 22
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
Aspartate/glutamate racemase Aspartate/glutamate racemase 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
PLP-binding barrel Alanine racemase C-terminal domain-like 21
PUA domain-like Ribosomal protein S5 domain 2-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
cAMP-binding domain-like CBS-domain pair 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 21
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
CheY-like EAL domain-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 21
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
MgtE N-terminal domain-like CBS-domain pair 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
PurS-like FGAM synthase PurL, linker domain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Peptide methionine sulfoxide reductase Mss4-like 11
Lysozyme-like PGBD-like 11
FKBP-like FKBP-like 11
Translation proteins ThrRS/AlaRS common domain 11
FAD/NAD(P)-binding domain PurM C-terminal domain-like 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Nucleotidyltransferase Nucleotidyltransferase 11
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 11
PurS-like PurM N-terminal domain-like 11
Zn-dependent exopeptidases LysM domain 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
Ribokinase-like Nucleotidylyl transferase 11
Phospholipase D/nuclease P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Translation proteins PRC-barrel domain 11
DNA-glycosylase Nudix 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Nudix Thiamin phosphate synthase 11
PheT/TilS domain Putative DNA-binding domain 11
Chorismate mutase II ACT-like 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
PYP-like sensor domain (PAS domain) Homeodomain-like 11
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 11
PIN domain-like DNA/RNA polymerases 11
Ribonuclease H-like DNA/RNA polymerases 11
Barwin-like endoglucanases Sporulation related repeat 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
ACT-like Formyltransferase 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Hedgehog/intein (Hint) domain Homing endonucleases 11
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 11
Nucleotide-binding domain Riboflavin synthase domain-like 11
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
P-loop containing nucleoside triphosphate hydrolases Hedgehog/intein (Hint) domain 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
CheY-like CheY-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Thioredoxin-like Six-hairpin glycosidases 11
Class II aaRS and biotin synthetases Translation proteins 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 11
CBS-domain pair MgtE membrane domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
GIY-YIG endonuclease RuvA domain 2-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
PYP-like sensor domain (PAS domain) GAF domain-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PurS-like Class I glutamine amidotransferase-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
N-terminal domain of DnaB helicase Homing endonucleases 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
Hsp33 domain HSP33 redox switch-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
FAD/NAD(P)-binding domain PurM N-terminal domain-like 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
PHP14-like Phospholipase D/nuclease 11
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
4Fe-4S ferredoxins ADC-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Translation proteins Ribosomal protein S10 11
DNA breaking-rejoining enzymes DNA breaking-rejoining enzymes 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
PreATP-grasp domain Methylglyoxal synthase-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Nucleic acid-binding proteins GAD domain-like 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
FAD/NAD(P)-binding domain Riboflavin synthase domain-like 11
PrpR receptor domain-like P-loop containing nucleoside triphosphate hydrolases 11
alpha/beta-Hydrolases OsmC-like 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Carbamate kinase-like ACT-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
ACP-like Glycerol-3-phosphate (1)-acyltransferase 11
P-loop containing nucleoside triphosphate hydrolases Acyl-CoA N-acyltransferases (Nat) 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 11
Acetyl-CoA synthetase-like Glycerol-3-phosphate (1)-acyltransferase 11
Thioesterase/thiol ester dehydrase-isomerase Isocitrate/Isopropylmalate dehydrogenase-like 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
PYP-like sensor domain (PAS domain) Ribonuclease H-like 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Single hybrid motif CoA-dependent acyltransferases 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
TerB-like Chaperone J-domain 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 11
Actin-like ATPase domain HD-domain/PDEase-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
TGS-like Class II aaRS ABD-related 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Acyl-CoA N-acyltransferases (Nat) 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Single hybrid motif FAD/NAD(P)-binding domain 11
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
PrpR receptor domain-like PYP-like sensor domain (PAS domain) 11
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 11
Ribosomal protein L6 Ribosomal protein L6 11
TGS-like ThrRS/AlaRS common domain 11
PurS-like PurM C-terminal domain-like 11
Pseudouridine synthase PUA domain-like 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
SIS domain CBS-domain pair 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
GroES-like GroES-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
RmlC-like cupins RmlC-like cupins 11
P-loop containing nucleoside triphosphate hydrolases LexA/Signal peptidase 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
TPR-like TPR-like 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
Translation proteins Translation proteins 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Nucleotidylyl transferase Riboflavin kinase-like 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
"Winged helix" DNA-binding domain GAF domain-like 11
YrdC/RibB RibA-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
Carbamate kinase-like PUA domain-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
ACT-like HAD-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Dihydropteroate synthetase-like Methionine synthase domain 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Acetyl-CoA synthetase-like ACP-like 11
YjeF N-terminal domain-like Ribokinase-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Formyltransferase FMT C-terminal domain-like 11
PPK N-terminal domain-like PHP14-like 11
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Resolvase-like Homeodomain-like 11
DNA clamp DNA clamp 11
GAF domain-like Phosphohistidine domain 11
Methionine synthase domain Methionine synthase activation domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
DinB/YfiT-like putative metalloenzymes C-type lectin-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
TGS-like Class II aaRS and biotin synthetases 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Putative DNA-binding domain Translation proteins 11
PUA domain-like Nucleotidylyl transferase 11
L30e-like alpha/beta knot 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
DNA primase core DNA primase DnaG, C-terminal domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
N-terminal domain of DnaB helicase Hedgehog/intein (Hint) domain 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
ClpP/crotonase NfeD domain-like 11
CarD-like TRCF domain-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
SMAD/FHA domain P-loop containing nucleoside triphosphate hydrolases 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
Chorismate mutase II Periplasmic binding protein-like II 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
GAF domain-like EAL domain-like 11
P-loop containing nucleoside triphosphate hydrolases UDP-Glycosyltransferase/glycogen phosphorylase 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
2Fe-2S ferredoxin-like ADC-like 11
Nucleotidylyl transferase P-loop containing nucleoside triphosphate hydrolases 11
Periplasmic binding protein-like II ACT-like 11
CheY-like PYP-like sensor domain (PAS domain) 11
RNase III domain-like dsRNA-binding domain-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
NagB/RpiA/CoA transferase-like DAK1/DegV-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S10 11
Nudix "Winged helix" DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Homing endonucleases 11
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
PreATP-grasp domain PreATP-grasp domain 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
Fic-like "Winged helix" DNA-binding domain 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Acyl-CoA N-acyltransferases (Nat) Carbon-nitrogen hydrolase 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Nucleic acid-binding proteins PheT/TilS domain 11
PP2C-like Protein kinase-like (PK-like) 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
MalF N-terminal region-like MetI-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
PIN domain-like Ribonuclease H-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
GroEL-intermediate domain like GroEL apical domain-like 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
PrpR receptor domain-like Homeodomain-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Tropomyosin OmpA-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
RuvA domain 2-like BRCT domain 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Zinc beta-ribbon DNA primase core 11
Nucleotidylyl transferase tRNA-binding arm 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
Nucleic acid-binding proteins BRCT domain 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
Class II aaRS and biotin synthetases GAD domain-like 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
FAD-linked oxidoreductase ALDH-like 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11

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