SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Gluconacetobacter xylinus NBRC 3288

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


Add or remove domain pairs

The links below permit the addition or removal of specific sets of domain combination pairs.


Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Add or remove genomes

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Add or remove genomes:
Include genomes:
Exclude genomes:


Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

531 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 271
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2514
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 157
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 145
Nucleotide cyclase EAL domain-like 137
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 124
PYP-like sensor domain (PAS domain) EAL domain-like 126
PYP-like sensor domain (PAS domain) Nucleotide cyclase 126
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 124
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 112
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 116
GroES-like NAD(P)-binding Rossmann-fold domains 113
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 105
Actin-like ATPase domain Actin-like ATPase domain 104
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 105
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 105
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 105
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 92
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 92
PYP-like sensor domain (PAS domain) GAF domain-like 84
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 84
GAF domain-like Nucleotide cyclase 84
Resolvase-like Homeodomain-like 81
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 71
CheY-like C-terminal effector domain of the bipartite response regulators 71
GAF domain-like EAL domain-like 73
P-loop containing nucleoside triphosphate hydrolases Translation proteins 76
ParB/Sulfiredoxin KorB DNA-binding domain-like 61
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 63
Thioredoxin-like GST C-terminal domain-like 61
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 61
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 64
Cytochrome c Cytochrome c 64
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 63
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 64
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 52
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 53
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 51
ISP domain Bet v1-like 51
PurM N-terminal domain-like PurM C-terminal domain-like 42
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 41
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 42
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 43
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 42
E set domains (Trans)glycosidases 43
S-adenosyl-L-methionine-dependent methyltransferases P-loop containing nucleoside triphosphate hydrolases 44
OMPA-like OmpA-like 42
Phospholipase D/nuclease Phospholipase D/nuclease 43
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 41
HlyD-like secretion proteins HlyD-like secretion proteins 41
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 42
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
FKBP-like Triger factor/SurA peptide-binding domain-like 43
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 42
Nucleic acid-binding proteins Nucleic acid-binding proteins 44
Translation proteins EF-G C-terminal domain-like 43
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 42
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 41
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
Homeodomain-like Homeodomain-like 43
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 42
CheY-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
cAMP-binding domain-like "Winged helix" DNA-binding domain 31
Trypsin-like serine proteases PDZ domain-like 32
"Winged helix" DNA-binding domain PLP-dependent transferases 32
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 31
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 31
CBS-domain pair FAD-binding/transporter-associated domain-like 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 31
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 32
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
E set domains Glycosyl hydrolase domain 32
TPR-like TPR-like 33
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 33
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 33
Bacterial muramidases Lysozyme-like 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 33
DNA methylase specificity domain DNA methylase specificity domain 31
Alpha-L RNA-binding motif Pseudouridine synthase 31
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Nucleotide-diphospho-sugar transferases PilZ domain-like 31
PreATP-grasp domain Rudiment single hybrid motif 31
ACT-like ACT-like 33
PLP-binding barrel Alanine racemase C-terminal domain-like 32
(Trans)glycosidases Glycosyl hydrolase domain 32
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 21
HAD-like Calcium ATPase, transmembrane domain M 22
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
PDZ domain-like ClpP/crotonase 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
CheY-like Homeodomain-like 21
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
CheY-like Homodimeric domain of signal transducing histidine kinase 22
"Winged helix" DNA-binding domain GAF domain-like 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Ribosomal protein S5 domain 2-like EF-G C-terminal domain-like 22
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 22
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 22
CheY-like CheY-like 22
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 22
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 21
NAD(P)-binding Rossmann-fold domains ACT-like 22
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 22
Calcium ATPase, transduction domain A HAD-like 22
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
PYP-like sensor domain (PAS domain) CheY-like 22
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 22
alpha-helical ferredoxin Nucleotide-binding domain 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
Origin of replication-binding domain, RBD-like P-loop containing nucleoside triphosphate hydrolases 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
CheY-like P-loop containing nucleoside triphosphate hydrolases 21
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 22
Nucleotide-diphospho-sugar transferases UDP-Glycosyltransferase/glycogen phosphorylase 21
Nucleotide-diphospho-sugar transferases RmlC-like cupins 21
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Nucleic acid-binding proteins RuvA domain 2-like 22
Phage tail proteins Phage tail proteins 21
Nucleotidyltransferase HD-domain/PDEase-like 22
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 21
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 21
PDZ domain-like PDZ domain-like 21
FAD/NAD(P)-binding domain HI0933 insert domain-like 21
Single hybrid motif CoA-dependent acyltransferases 21
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Zinc beta-ribbon DNA primase core 11
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Methionine synthase domain Methionine synthase activation domain-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Nucleotidylyl transferase tRNA-binding arm 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
P-loop containing nucleoside triphosphate hydrolases Adenine nucleotide alpha hydrolases-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Carbamate kinase-like ACT-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Acyl-CoA N-acyltransferases (Nat) Nudix 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
Nucleic acid-binding proteins PheT/TilS domain 11
Nucleotidyltransferase ACT-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Voltage-gated potassium channels E set domains 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
lambda repressor-like DNA-binding domains Class I glutamine amidotransferase-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 11
Actin-like ATPase domain HD-domain/PDEase-like 11
"Winged helix" DNA-binding domain HRDC-like 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
RuvA domain 2-like BRCT domain 11
MetI-like MetI-like 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Formyltransferase FMT C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
Homeodomain-like Ribonuclease H-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
YrdC/RibB RibA-like 11
PLP-dependent transferases PLP-dependent transferases 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
HCP-like HCP-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain TPR-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
CheW-like CheY-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
PHP14-like Phospholipase D/nuclease 11
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 11
TGS-like Class II aaRS ABD-related 11
Single hybrid motif Thiamin diphosphate-binding fold (THDP-binding) 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Periplasmic binding protein-like II MetI-like 11
DAK1/DegV-like DhaL-like 11
Ribonuclease H-like DNA/RNA polymerases 11
Globin-like Riboflavin synthase domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
GAF domain-like Homodimeric domain of signal transducing histidine kinase 11
Quinoprotein alcohol dehydrogenase-like Cytochrome c 11
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 11
HMA, heavy metal-associated domain HAD-like 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Acid proteases Acid proteases 11
Carbamate kinase-like PUA domain-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Nucleotidyltransferase Nucleotidyltransferase 11
ACT-like Formyltransferase 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
GIY-YIG endonuclease RuvA domain 2-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
lambda repressor-like DNA-binding domains Carbamoyl phosphate synthetase, small subunit N-terminal domain 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
TGS-like Class II aaRS and biotin synthetases 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
FMN-linked oxidoreductases 4Fe-4S ferredoxins 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Histidine-containing phosphotransfer domain, HPT domain CheY-like 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
lambda repressor-like DNA-binding domains LexA/Signal peptidase 11
PK beta-barrel domain-like PK C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
GAF domain-like GAF domain-like 11
RmlC-like cupins Homeodomain-like 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Class II aaRS and biotin synthetases Translation proteins 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Adenine nucleotide alpha hydrolases-like GAF domain-like 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Fic-like "Winged helix" DNA-binding domain 11
DNA-glycosylase Nudix 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
vWA-like Class I glutamine amidotransferase-like 11
Nudix "Winged helix" DNA-binding domain 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
UROD/MetE-like UROD/MetE-like 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
GroEL equatorial domain-like GroEL apical domain-like 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Homodimeric domain of signal transducing histidine kinase 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Translation proteins ThrRS/AlaRS common domain 11
PPK N-terminal domain-like PHP14-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
Macro domain-like Zn-dependent exopeptidases 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Cupredoxins Cupredoxins 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Phosphoglycerate mutase-like "Winged helix" DNA-binding domain 11
TerB-like Chaperone J-domain 11
GroEL-intermediate domain like GroEL apical domain-like 11
RNase III domain-like dsRNA-binding domain-like 11
Ribosomal protein L6 Ribosomal protein L6 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Translation proteins PRC-barrel domain 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Galactose mutarotase-like Six-hairpin glycosidases 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Translation proteins Translation proteins 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
HD-domain/PDEase-like TGS-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
GAF domain-like CheY-like 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Heme-dependent catalase-like Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Class I glutamine amidotransferase-like Homeodomain-like 11
GroES-like GroES-like 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
GAF domain-like Homeodomain-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
CarD-like TRCF domain-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
P-loop containing nucleoside triphosphate hydrolases GAF domain-like 11
Galactose mutarotase-like E set domains 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Single hybrid motif alpha/beta-Hydrolases 11
Single hybrid motif TK C-terminal domain-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
CheY-like Methylesterase CheB, C-terminal domain 11
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
lambda repressor-like DNA-binding domains lambda repressor-like DNA-binding domains 11
Aldolase SIS domain 11
E set domains E set domains 11
Nucleic acid-binding proteins BRCT domain 11
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 11
Periplasmic binding protein-like II ACT-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Nucleic acid-binding proteins GAD domain-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
"Winged helix" DNA-binding domain Chorismate lyase-like 11
P-loop containing nucleoside triphosphate hydrolases MOP-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
PreATP-grasp domain PreATP-grasp domain 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Restriction endonuclease-like P-loop containing nucleoside triphosphate hydrolases 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Dihydropteroate synthetase-like Methionine synthase domain 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
Cobalamin (vitamin B12)-binding domain Radical SAM enzymes 11
"Winged helix" DNA-binding domain Iron-dependent repressor protein, dimerization domain 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Thioredoxin-like Thioredoxin-like 11
PUA domain-like alpha/beta knot 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
P-loop containing nucleoside triphosphate hydrolases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
"Winged helix" DNA-binding domain Ribokinase-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
PIN domain-like Ribonuclease H-like 11
YlxR-like L30e-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
DPP6 N-terminal domain-like alpha/beta-Hydrolases 11
PIN domain-like DNA/RNA polymerases 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Trigger factor ribosome-binding domain FKBP-like 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Nqo5-like HydB/Nqo4-like 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
YjeF N-terminal domain-like Ribokinase-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Inosine monophosphate dehydrogenase (IMPDH) Nitrite and sulphite reductase 4Fe-4S domain-like 11
Thioredoxin-like TPR-like 11
Single hybrid motif FAD/NAD(P)-binding domain 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
DNA clamp DNA clamp 11
P-loop containing nucleoside triphosphate hydrolases Microbial and mitochondrial ADK, insert "zinc finger" domain 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Galactose mutarotase-like Galactose mutarotase-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Acyl-CoA N-acyltransferases (Nat) Ribulose-phoshate binding barrel 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
"Winged helix" DNA-binding domain NosL/MerB-like 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
S-adenosyl-L-methionine-dependent methyltransferases TPR-like 11
Hsp33 domain HSP33 redox switch-like 11
HRDC-like HRDC-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Ribokinase-like Nucleotidylyl transferase 11
Ribonuclease H-like HRDC-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Nucleotidyltransferase TGS-like 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
TGS-like ThrRS/AlaRS common domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Homeodomain-like SIS domain 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Restriction endonuclease-like S-adenosyl-L-methionine-dependent methyltransferases 11
HD-domain/PDEase-like ACT-like 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
L30e-like alpha/beta knot 11
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 11
P-loop containing nucleoside triphosphate hydrolases Dehydroquinate synthase-like 11
Thiolase-like Thiolase-like 11

Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes · Domain combination pairs ]