SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Francisella sp. TX077308

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

480 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 1210
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 111
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 93
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 86
Actin-like ATPase domain Actin-like ATPase domain 82
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 72
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 74
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 73
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 64
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 52
P-loop containing nucleoside triphosphate hydrolases Translation proteins 55
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 52
PLP-binding barrel Alanine racemase C-terminal domain-like 52
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 53
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 42
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 43
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 42
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 42
PreATP-grasp domain Rudiment single hybrid motif 42
Thiolase-like Thiolase-like 41
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 44
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 33
GroES-like NAD(P)-binding Rossmann-fold domains 33
Alpha-L RNA-binding motif Pseudouridine synthase 31
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Thioredoxin-like GST C-terminal domain-like 31
Carbohydrate binding domain Carbohydrate binding domain 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 31
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 32
Translation proteins EF-G C-terminal domain-like 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 31
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
CBS-domain pair FAD-binding/transporter-associated domain-like 31
PurM N-terminal domain-like PurM C-terminal domain-like 32
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 31
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 22
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 21
HD-domain/PDEase-like TGS-like 22
NAD(P)-binding Rossmann-fold domains ACP-like 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 21
Phospholipase D/nuclease Phospholipase D/nuclease 21
E set domains Carbohydrate binding domain 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 22
HCP-like HCP-like 22
ACT-like ACT-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 21
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Carbamate kinase-like ACT-like 22
lambda repressor-like DNA-binding domains LexA/Signal peptidase 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Nucleotidyltransferase TGS-like 22
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
MetI-like MetI-like 22
(Trans)glycosidases (Trans)glycosidases 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
TrkA C-terminal domain-like TrkA C-terminal domain-like 22
Triger factor/SurA peptide-binding domain-like FKBP-like 22
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 22
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 22
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Enolase N-terminal domain-like Enolase C-terminal domain-like 21
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 22
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 21
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 21
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
NAD(P)-binding Rossmann-fold domains ACT-like 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Nucleic acid-binding proteins RuvA domain 2-like 22
CheY-like C-terminal effector domain of the bipartite response regulators 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 21
Carbohydrate binding domain (Trans)glycosidases 21
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
L30e-like alpha/beta knot 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
Single hybrid motif Single hybrid motif 22
(Trans)glycosidases Glycosyl hydrolase domain 22
E set domains (Trans)glycosidases 22
HD-domain/PDEase-like Nucleotidyltransferase 22
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
MetI-like Periplasmic binding protein-like II 11
Nucleotidylyl transferase tRNA-binding arm 11
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
PurS-like Class I glutamine amidotransferase-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Calcium ATPase, transduction domain A HAD-like 11
Macro domain-like Zn-dependent exopeptidases 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
PUA domain-like alpha/beta knot 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
TGS-like Class II aaRS ABD-related 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 11
"Winged helix" DNA-binding domain GAF domain-like 11
TGS-like ThrRS/AlaRS common domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
TGS-like ACT-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Ribosomal protein L6 Ribosomal protein L6 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Dimeric alpha+beta barrel AhpD-like 11
Carbamate kinase-like PUA domain-like 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
P-loop containing nucleoside triphosphate hydrolases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
SAICAR synthase-like Glutathione synthetase ATP-binding domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Translation proteins Ribosomal protein S5 domain 2-like 11
PheT/TilS domain Putative DNA-binding domain 11
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 11
Purine and uridine phosphorylases alpha/beta-Hydrolases 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
GIY-YIG endonuclease RuvA domain 2-like 11
Galactose mutarotase-like (Trans)glycosidases 11
ACT-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 11
HlyD-like secretion proteins HlyD-like secretion proteins 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Zinc beta-ribbon Zinc beta-ribbon 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Acyl-CoA binding protein ClpP/crotonase 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Nucleotidylyl transferase Riboflavin kinase-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
CarD-like TRCF domain-like 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
Thiolase-like GroES-like 11
Periplasmic binding protein-like II GlnB-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 11
ALDH-like ALDH-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
RNase III domain-like dsRNA-binding domain-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
PreATP-grasp domain PreATP-grasp domain 11
6-phosphogluconate dehydrogenase C-terminal domain-like ClpP/crotonase 11
GroEL-intermediate domain like GroEL apical domain-like 11
Thiolase-like NAD(P)-binding Rossmann-fold domains 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Periplasmic binding protein-like II ACT-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
FabD/lysophospholipase-like ACP-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
beta-lactamase/transpeptidase-like Ankyrin repeat 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK Dihydropteroate synthetase-like 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 11
PurS-like PurM N-terminal domain-like 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 11
Phospholipase D/nuclease P-loop containing nucleoside triphosphate hydrolases 11
Zinc beta-ribbon DNA primase core 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
FabD/lysophospholipase-like GroES-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
Galactose mutarotase-like Glycosyl hydrolase domain 11
GroES-like ACP-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Globin-like Riboflavin synthase domain-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
FKBP-like FKBP-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Translation proteins ThrRS/AlaRS common domain 11
TPR-like TPR-like 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
GroES-like GroES-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
PIN domain-like Ribonuclease H-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Nucleic acid-binding proteins PheT/TilS domain 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
HisI-like all-alpha NTP pyrophosphatases 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
Nucleotidylyl transferase Nudix 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
Acyl-CoA binding protein NAD(P)-binding Rossmann-fold domains 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
Putative DNA-binding domain Translation proteins 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
E set domains Glycosyl hydrolase domain 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
P-loop containing nucleoside triphosphate hydrolases MOP-like 11
HD-domain/PDEase-like ACT-like 11
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 11
Translation proteins PRC-barrel domain 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Ribulose-phoshate binding barrel Ribulose-phoshate binding barrel 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
YrdC/RibB RibA-like 11
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
P-loop containing nucleoside triphosphate hydrolases beta-sandwich domain of Sec23/24 11
HRDC-like HRDC-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase GroES-like 11
DeoB insert domain-like Alkaline phosphatase-like 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
Nucleotidyltransferase ACT-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
YjeF N-terminal domain-like Ribokinase-like 11
Acetyl-CoA synthetase-like NAD(P)-binding Rossmann-fold domains 11
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, peptide-binding domain 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
ACT-like Formyltransferase 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
OMPA-like OmpA-like 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
SAICAR synthase-like Rudiment single hybrid motif 11
PurS-like PurM C-terminal domain-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
HIT-like HIT-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
HAD-like Calcium ATPase, transmembrane domain M 11
HAD-like Ribosomal protein S5 domain 2-like 11
Acid proteases Acid proteases 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
RmlC-like cupins Homeodomain-like 11
Single hybrid motif CoA-dependent acyltransferases 11
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Thiolase-like ACP-like 11
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 11
GroEL equatorial domain-like GroEL apical domain-like 11
Formyltransferase FMT C-terminal domain-like 11
Nicotinic receptor ligand binding domain-like Neurotransmitter-gated ion-channel transmembrane pore 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 11
Ribonuclease H-like HRDC-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
TGS-like Class II aaRS and biotin synthetases 11
P-loop containing nucleoside triphosphate hydrolases Adenine nucleotide alpha hydrolases-like 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
Ribonuclease H-like DNA/RNA polymerases 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
FAD/NAD(P)-binding domain Rhodanese/Cell cycle control phosphatase 11
RuvA domain 2-like BRCT domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
DNA methylase specificity domain DNA methylase specificity domain 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Mss4-like Peptide methionine sulfoxide reductase 11
Nucleic acid-binding proteins GAD domain-like 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Acetyl-CoA synthetase-like ACP-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Acyl-CoA binding protein 6-phosphogluconate dehydrogenase C-terminal domain-like 11
SAICAR synthase-like PreATP-grasp domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
post-AAA+ oligomerization domain-like beta-sandwich domain of Sec23/24 11
Carbamate kinase-like NAD(P)-binding Rossmann-fold domains 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
FAD/NAD-linked reductases, dimerisation (C-terminal) domain Rhodanese/Cell cycle control phosphatase 11
Carbohydrate binding domain Lysozyme-like 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
HD-domain/PDEase-like HD-domain/PDEase-like 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
beta-N-acetylhexosaminidase-like domain (Trans)glycosidases 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
FAD-linked oxidoreductase ALDH-like 11
Trigger factor ribosome-binding domain FKBP-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Ribokinase-like Thiamin phosphate synthase 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Thiolase-like FabD/lysophospholipase-like 11
PIN domain-like DNA/RNA polymerases 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases GAD domain-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
"Winged helix" DNA-binding domain C-terminal domain of arginine repressor 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains ClpP/crotonase 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, catalytic domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Cysteine proteinases 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
Acyl-CoA N-acyltransferases (Nat) Carbon-nitrogen hydrolase 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
P-loop containing nucleoside triphosphate hydrolases Homodimeric domain of signal transducing histidine kinase 11
Carbamate kinase-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
Bacterial muramidases Lysozyme-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
ISP domain Bet v1-like 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
PurS-like FGAM synthase PurL, linker domain 11
Nucleic acid-binding proteins BRCT domain 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Nucleotide-diphospho-sugar transferases UDP-Glycosyltransferase/glycogen phosphorylase 11
Translation proteins Translation proteins 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
DNA clamp DNA clamp 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Thioredoxin-like Ferritin-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11

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