SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Cupriavidus necator N-1

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

770 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 2102
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 685
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 4421
"Winged helix" DNA-binding domain GAF domain-like 431
GroES-like NAD(P)-binding Rossmann-fold domains 382
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 3415
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 343
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 333
CheY-like C-terminal effector domain of the bipartite response regulators 323
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 319
Thiolase-like Thiolase-like 311
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 305
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 297
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 297
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 286
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 273
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 272
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 236
Thioredoxin-like GST C-terminal domain-like 232
Homeodomain-like P-loop containing nucleoside triphosphate hydrolases 2211
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 214
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 214
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 203
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 204
Homeodomain-like Homeodomain-like 195
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 186
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 186
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 187
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 183
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 175
"Winged helix" DNA-binding domain PLP-dependent transferases 172
Actin-like ATPase domain Actin-like ATPase domain 176
P-loop containing nucleoside triphosphate hydrolases TPR-like 178
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 175
"Winged helix" DNA-binding domain Chorismate lyase-like 172
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 175
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 164
ISP domain Bet v1-like 152
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 155
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 151
PreATP-grasp domain Rudiment single hybrid motif 155
P-loop containing nucleoside triphosphate hydrolases C-terminal effector domain of the bipartite response regulators 146
TPR-like TPR-like 149
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 144
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 135
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 131
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 136
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 123
Cytochrome c Cytochrome c 125
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1211
P-loop containing nucleoside triphosphate hydrolases Translation proteins 127
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 1210
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 115
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 1110
ClpP/crotonase ClpP/crotonase 113
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 104
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 103
PYP-like sensor domain (PAS domain) Nucleotide cyclase 107
cAMP-binding domain-like "Winged helix" DNA-binding domain 102
Homodimeric domain of signal transducing histidine kinase CheY-like 108
Nucleotide cyclase TPR-like 105
Nucleotide cyclase P-loop containing nucleoside triphosphate hydrolases 105
CheY-like Homeodomain-like 93
P-loop containing nucleoside triphosphate hydrolases MOP-like 91
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 98
EAL domain-like Nucleotide cyclase 97
TPR-like C-terminal effector domain of the bipartite response regulators 95
CheY-like P-loop containing nucleoside triphosphate hydrolases 93
Aldolase post-HMGL domain-like 93
Enolase N-terminal domain-like Enolase C-terminal domain-like 91
Glutathione synthetase ATP-binding domain-like Single hybrid motif 93
Rudiment single hybrid motif Single hybrid motif 93
PreATP-grasp domain Single hybrid motif 93
Class I glutamine amidotransferase-like Homeodomain-like 83
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 85
Phospholipase D/nuclease Phospholipase D/nuclease 85
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 72
Homeodomain-like Ribonuclease H-like 74
Molybdenum cofactor-binding domain CO dehydrogenase molybdoprotein N-domain-like 72
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 72
HlyD-like secretion proteins HlyD-like secretion proteins 72
P-loop containing nucleoside triphosphate hydrolases GAF domain-like 74
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 71
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 72
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 73
ParB/Sulfiredoxin KorB DNA-binding domain-like 62
Lysozyme-like beta-lactamase/transpeptidase-like 64
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 62
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 61
Homeodomain-like SIS domain 62
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 61
Translation proteins EF-G C-terminal domain-like 63
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 63
LeuD/IlvD-like Aconitase iron-sulfur domain 63
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 63
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 64
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 63
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 62
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 52
MetI-like MetI-like 52
P-loop containing nucleoside triphosphate hydrolases PYP-like sensor domain (PAS domain) 53
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 52
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 52
PurM N-terminal domain-like PurM C-terminal domain-like 52
PYP-like sensor domain (PAS domain) EAL domain-like 54
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 55
Triger factor/SurA peptide-binding domain-like FKBP-like 54
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 53
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 54
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 53
Calcium ATPase, transduction domain A HAD-like 55
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 53
EF-G C-terminal domain-like EF-G C-terminal domain-like 52
GAF domain-like Homeodomain-like 53
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 52
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 52
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 52
HAD-like Calcium ATPase, transmembrane domain M 55
Alpha-L RNA-binding motif Pseudouridine synthase 53
PYP-like sensor domain (PAS domain) CheY-like 55
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 52
ADC-like 2Fe-2S ferredoxin-like 42
PLP-binding barrel Alanine racemase C-terminal domain-like 42
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 43
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 43
GAF domain-like Homodimeric domain of signal transducing histidine kinase 43
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 41
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 43
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 43
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 41
Oxidoreductase molybdopterin-binding domain E set domains 42
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 43
PK beta-barrel domain-like PK C-terminal domain-like 41
Formate dehydrogenase/DMSO reductase, domains 1-3 2Fe-2S ferredoxin-like 42
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 42
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 43
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
Nucleic acid-binding proteins Nucleic acid-binding proteins 43
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 41
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 42
ACT-like ACT-like 43
Trypsin-like serine proteases PDZ domain-like 43
Nqo1 middle domain-like Nqo1C-terminal domain-like 43
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 42
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 43
lambda repressor-like DNA-binding domains RmlC-like cupins 42
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 33
CBS-domain pair FAD-binding/transporter-associated domain-like 31
HMA, heavy metal-associated domain HAD-like 33
Histidine-containing phosphotransfer domain, HPT domain CheW-like 33
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 33
Glutathione synthetase ATP-binding domain-like post-HMGL domain-like 31
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 32
Rudiment single hybrid motif Aldolase 31
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 32
Nucleic acid-binding proteins RuvA domain 2-like 33
2Fe-2S ferredoxin-like alpha-helical ferredoxin 31
HD-domain/PDEase-like Nucleotidyltransferase 33
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 33
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
post-HMGL domain-like Single hybrid motif 31
Single hybrid motif CoA-dependent acyltransferases 32
HD-domain/PDEase-like ACT-like 33
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
E set domains (Trans)glycosidases 33
Aldolase Single hybrid motif 31
Rudiment single hybrid motif post-HMGL domain-like 31
Glutathione synthetase ATP-binding domain-like Aldolase 31
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 31
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 33
Histidine-containing phosphotransfer domain, HPT domain CheY-like 33
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 32
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 32
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 32
GAF domain-like PYP-like sensor domain (PAS domain) 32
Translation proteins Ribosomal protein S5 domain 2-like 31
PDZ domain-like PDZ domain-like 32
PreATP-grasp domain Aldolase 31
PYP-like sensor domain (PAS domain) Homeodomain-like 32
Nucleotidyltransferase ACT-like 33
(Trans)glycosidases Glycosyl hydrolase domain 33
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 32
CheW-like CheY-like 33
Nucleotide-diphospho-sugar transferases PilZ domain-like 32
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 32
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 31
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 31
GroES-like GroES-like 31
Translation proteins SH3-like domain Nucleic acid-binding proteins 32
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 31
RmlC-like cupins Homeodomain-like 31
4Fe-4S ferredoxins Ferredoxin reductase-like, C-terminal NADP-linked domain 31
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 31
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 32
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 32
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
PreATP-grasp domain post-HMGL domain-like 31
4Fe-4S ferredoxins ADC-like 31
4Fe-4S ferredoxins Riboflavin synthase domain-like 31
Cytochrome c C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 22
P-loop containing nucleoside triphosphate hydrolases Homodimeric domain of signal transducing histidine kinase 21
Protein kinase-like (PK-like) PYP-like sensor domain (PAS domain) 21
FMN-dependent nitroreductase-like FMN-dependent nitroreductase-like 22
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 21
E set domains Glycosyl hydrolase domain 22
NagB/RpiA/CoA transferase-like 4Fe-4S ferredoxins 21
FAD/NAD(P)-binding domain HI0933 insert domain-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Protein kinase-like (PK-like) GAF domain-like 21
RuBisCO, large subunit, small (N-terminal) domain RuBisCo, C-terminal domain 21
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 22
Thioredoxin-like Nqo1 middle domain-like 22
P-loop containing nucleoside triphosphate hydrolases TGS-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
NAD(P)-binding Rossmann-fold domains ACT-like 22
HD-domain/PDEase-like TGS-like 22
Nucleotidyltransferase TGS-like 22
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
PHP14-like Phospholipase D/nuclease 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
ACT-like Formyltransferase 21
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 22
Cytochrome P450 Riboflavin synthase domain-like 22
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 21
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 21
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
Thioredoxin-like Nqo1 FMN-binding domain-like 22
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 21
Glutathione synthetase ATP-binding domain-like ClpP/crotonase 21
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 21
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 21
4Fe-4S ferredoxins Respiratory nitrate reductase 1 gamma chain 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Galactose mutarotase-like E set domains 21
Regulatory protein AraC Homeodomain-like 21
CoA-transferase family III (CaiB/BaiF) CoA-transferase family III (CaiB/BaiF) 21
Cytochrome P450 Ferredoxin reductase-like, C-terminal NADP-linked domain 22
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 21
Globin-like Riboflavin synthase domain-like 21
PrpR receptor domain-like PYP-like sensor domain (PAS domain) 21
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 22
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 21
P-loop containing nucleoside triphosphate hydrolases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 22
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 21
PH0987 N-terminal domain-like Cyclophilin-like 22
Folate-binding domain Aminomethyltransferase beta-barrel domain 22
Cupredoxins Cytochrome c 22
Formyltransferase FMT C-terminal domain-like 21
C-terminal effector domain of the bipartite response regulators Nucleotide cyclase 22
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 21
Flavoproteins Riboflavin synthase domain-like 22
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, peptide-binding domain 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
PrpR receptor domain-like P-loop containing nucleoside triphosphate hydrolases 21
PrpR receptor domain-like Homeodomain-like 21
Thioredoxin-like Nqo1C-terminal domain-like 22
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
YrdC/RibB RibA-like 21
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Quinoprotein alcohol dehydrogenase-like Cytochrome c 22
PreATP-grasp domain ClpP/crotonase 21
L30e-like alpha/beta knot 21
Clc chloride channel CBS-domain pair 21
Protein kinase-like (PK-like) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 21
TGS-like ACT-like 22
Protein kinase-like (PK-like) Homodimeric domain of signal transducing histidine kinase 21
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase NM domain-like 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Acyl-CoA dehydrogenase C-terminal domain-like Acyl-CoA dehydrogenase C-terminal domain-like 21
DinB/YfiT-like putative metalloenzymes C-type lectin-like 21
MoeA N-terminal region -like MoeA C-terminal domain-like 21
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 22
Translation proteins ThrRS/AlaRS common domain 22
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 21
Nucleotide-diphospho-sugar transferases RmlC-like cupins 21
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 22
CheY-like Nucleotide cyclase 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
Single hybrid motif ClpP/crotonase 21
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 21
PPK N-terminal domain-like Phospholipase D/nuclease 22
CheY-like Methylesterase CheB, C-terminal domain 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Ribonuclease H-like DNA/RNA polymerases 22
Rudiment single hybrid motif ClpP/crotonase 21
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 21
PPK N-terminal domain-like PHP14-like 22
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 21
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, catalytic domain 21
lambda repressor-like DNA-binding domains P-loop containing nucleoside triphosphate hydrolases 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 22
Chorismate mutase II Periplasmic binding protein-like II 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
Ribonuclease H-like Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
Ligand-binding domain in the NO signalling and Golgi transport P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase tRNA-binding arm 11
"Winged helix" DNA-binding domain MOP-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
ALDH-like ALDH-like 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Nucleic acid-binding proteins PheT/TilS domain 11
beta-Roll beta-Roll 11
2Fe-2S ferredoxin-like Nucleotide cyclase 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
ACP-like Acetyl-CoA synthetase-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
PurS-like PurM N-terminal domain-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
alpha/beta-Hydrolases AhpD-like 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
Fumarate reductase respiratory complex transmembrane subunits Nucleotide cyclase 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
RmlC-like cupins RmlC-like cupins 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Kelch motif Galactose oxidase, central domain 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Translation proteins Translation proteins 11
CheY-binding domain of CheA CheW-like 11
Ligand-binding domain in the NO signalling and Golgi transport Homeodomain-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases FAD/NAD(P)-binding domain 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Nucleotide-binding domain Nucleotide-binding domain 11
LysM domain Duplicated hybrid motif 11
Thioredoxin-like TPR-like 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Nucleotide cyclase SMAD/FHA domain 11
alpha/beta-Hydrolases C-terminal effector domain of the bipartite response regulators 11
HD-domain/PDEase-like HD-domain/PDEase-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) DNA-glycosylase 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
DNA clamp DNA clamp 11
ISP domain FAD/NAD(P)-binding domain 11
Nucleic acid-binding proteins BRCT domain 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
TTHA1013/TTHA0281-like lambda repressor-like DNA-binding domains 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
KorB DNA-binding domain-like H-NS histone-like proteins 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
PLP-dependent transferases PLP-dependent transferases 11
FAD-linked oxidoreductase ALDH-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Putative DNA-binding domain Translation proteins 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
TGS-like Class II aaRS and biotin synthetases 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
PurS-like FGAM synthase PurL, linker domain 11
Cytochrome P450 2Fe-2S ferredoxin-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Macro domain-like Zn-dependent exopeptidases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
alpha/beta-Hydrolases FMN-binding split barrel 11
Hsp33 domain HSP33 redox switch-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Pili subunits Pili subunits 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
FAD/NAD(P)-binding domain Folate-binding domain 11
HD-domain/PDEase-like "Winged helix" DNA-binding domain 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Nucleic acid-binding proteins GAD domain-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
Ribonuclease H-like RuvA domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases WGR domain-like 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
PGBD-like L,D-transpeptidase catalytic domain-like 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
Aspartate receptor, ligand-binding domain Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Riboflavin synthase domain-like 11
RNase III domain-like dsRNA-binding domain-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Acetyl-CoA synthetase-like Thioesterase/thiol ester dehydrase-isomerase 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Single hybrid motif Single hybrid motif 11
4Fe-4S ferredoxins Iron-sulfur subunit of formate dehydrogenase N, transmembrane anchor 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
Metallo-hydrolase/oxidoreductase SCP-like 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Trigger factor ribosome-binding domain FKBP-like 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
FMN-linked oxidoreductases Nucleotide-binding domain 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Ribbon-helix-helix ALDH-like 11
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
PRTase-like alpha/beta-Hydrolases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Thioredoxin-like Six-hairpin glycosidases 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Actin-like ATPase domain HD-domain/PDEase-like 11
2Fe-2S ferredoxin-like Bet v1-like 11
E set domains E set domains 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Periplasmic binding protein-like II Lysozyme-like 11
FAD/NAD(P)-binding domain Thioredoxin-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
FAD-linked reductases, C-terminal domain Aminomethyltransferase beta-barrel domain 11
YajQ-like YajQ-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
Acetyl-CoA synthetase-like Glycerol-3-phosphate (1)-acyltransferase 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Sialidases Sialidases 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
PIN domain-like Ribonuclease H-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Periplasmic binding protein-like II ACT-like 11
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 11
Single hybrid motif FAD/NAD(P)-binding domain 11
CarD-like TRCF domain-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
RuvA domain 2-like BRCT domain 11
DNA breaking-rejoining enzymes Homeodomain-like 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Adenine nucleotide alpha hydrolases-like GAF domain-like 11
FabD/lysophospholipase-like FabD/lysophospholipase-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
ACP-like Glycerol-3-phosphate (1)-acyltransferase 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
ClpP/crotonase NfeD domain-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
CheY-like CheY-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Cadherin-like Kelch motif 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
PheT/TilS domain Putative DNA-binding domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Sensory domain-like HAMP domain-like 11
ParB/Sulfiredoxin H-NS histone-like proteins 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Alkaline phosphatase-like Concanavalin A-like lectins/glucanases 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Galactose mutarotase-like Galactose mutarotase-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Rhodanese/Cell cycle control phosphatase P-loop containing nucleoside triphosphate hydrolases 11
Glycosyl hydrolase domain Protein kinase-like (PK-like) 11
ADC-like Riboflavin synthase domain-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
CO dehydrogenase ISP C-domain like Bet v1-like 11
PreATP-grasp domain PreATP-grasp domain 11
Tex N-terminal region-like RuvA domain 2-like 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain "Winged helix" DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
lambda repressor-like DNA-binding domains PYP-like sensor domain (PAS domain) 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Cadherin-like Cadherin-like 11
FliG FliG 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Histidine-containing phosphotransfer domain, HPT domain CheY-binding domain of CheA 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
TGS-like ThrRS/AlaRS common domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
YjeF N-terminal domain-like Ribokinase-like 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
UROD/MetE-like UROD/MetE-like 11
alpha/beta-Hydrolases NTF2-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Pili subunits GspK insert domain-like 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
CheY-binding domain of CheA Homodimeric domain of signal transducing histidine kinase 11
Translation proteins "Winged helix" DNA-binding domain 11
Zinc beta-ribbon DNA primase core 11
P-loop containing nucleoside triphosphate hydrolases Pyrimidine nucleoside phosphorylase C-terminal domain 11
AhpD-like AhpD-like 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Galactose mutarotase-like Six-hairpin glycosidases 11
Methionine synthase domain Methionine synthase activation domain-like 11
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
Carbamate kinase-like ACT-like 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
HAMP domain-like GAF domain-like 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
Periplasmic binding protein-like II MetI-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
cAMP-binding domain-like FAD/NAD(P)-binding domain 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Bet v1-like PEBP-like 11
Chorismate mutase II ACT-like 11
S-adenosyl-L-methionine-dependent methyltransferases TPR-like 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Class II aaRS and biotin synthetases Translation proteins 11
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 11
"Winged helix" DNA-binding domain Rhodanese/Cell cycle control phosphatase 11
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 11
Carbamate kinase-like PUA domain-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
GAF domain-like EAL domain-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Molybdenum cofactor-binding domain Cytochrome c 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Lysozyme-like LysM domain 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
Homeodomain-like C-terminal effector domain of the bipartite response regulators 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
PurS-like PurM C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
Cadherin-like Galactose oxidase, central domain 11
PurS-like Class I glutamine amidotransferase-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Homeodomain-like TATA-box binding protein-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
PIN domain-like DNA/RNA polymerases 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Bacterial muramidases Lysozyme-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
GAF domain-like Nucleotide cyclase 11
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
HprK N-terminal domain-like PEP carboxykinase-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
cAMP-binding domain-like ABC transporter transmembrane region 11
ADC-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) TATA-box binding protein-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
alpha/beta-Hydrolases alpha/beta-Hydrolases 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
FKBP-like FKBP-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
PYP-like sensor domain (PAS domain) Ribonuclease H-like 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
GAF domain-like HD-domain/PDEase-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
PUA domain-like alpha/beta knot 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Phase 1 flagellin Phase 1 flagellin 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
P-loop containing nucleoside triphosphate hydrolases Cobalamin (vitamin B12)-dependent enzymes 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Class I glutamine amidotransferase-like Class I glutamine amidotransferase-like 11
GroEL-intermediate domain like GroEL apical domain-like 11
CheY-binding domain of CheA ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Nudix S-adenosyl-L-methionine-dependent methyltransferases 11
RuvA domain 2-like RuvA domain 2-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Cobalamin (vitamin B12)-binding domain P-loop containing nucleoside triphosphate hydrolases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Fumarate reductase respiratory complex transmembrane subunits 2Fe-2S ferredoxin-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
Ribbon-helix-helix N-terminal domain of bifunctional PutA protein 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Ribonuclease H-like GIY-YIG endonuclease 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
PreATP-grasp domain Methylglyoxal synthase-like 11
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
cAMP-binding domain-like cAMP-binding domain-like 11
cAMP-binding domain-like P-loop containing nucleoside triphosphate hydrolases 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
DNA-glycosylase Nudix 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
TPR-like FMN-dependent nitroreductase-like 11
Homeodomain-like Acetamidase/Formamidase-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Nudix Metallo-hydrolase/oxidoreductase 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Single hybrid motif alpha/beta-Hydrolases 11
FAD-linked reductases, C-terminal domain Folate-binding domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
CBS-domain pair Nucleotide cyclase 11
Nqo5-like HydB/Nqo4-like 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 11
Ribbon-helix-helix FAD-linked oxidoreductase 11
Ribosomal protein L6 Ribosomal protein L6 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
PDZ domain-like ClpP/crotonase 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
TATA-box binding protein-like DNA-glycosylase 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Translation proteins PRC-barrel domain 11
(Trans)glycosidases (Trans)glycosidases 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
EAL domain-like CBS-domain pair 11
Pseudouridine synthase PUA domain-like 11
Tex N-terminal region-like Ribonuclease H-like 11
CheC-like Surface presentation of antigens (SPOA) 11
alpha-helical ferredoxin Nucleotide-binding domain 11
TGS-like Class II aaRS ABD-related 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Cytochrome P450 Flavoproteins 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Homeodomain-like TPR-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Phage tail proteins Phage tail proteins 11
alpha/beta-Hydrolases S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
Cupredoxins Cupredoxins 11
Dihydropteroate synthetase-like Methionine synthase domain 11
SMAD/FHA domain SMAD/FHA domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Metalloproteases ("zincins"), catalytic domain PDZ domain-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
ISP domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Cyclophilin-like Cyclophilin-like 11
MOP-like MOP-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Homodimeric domain of signal transducing histidine kinase Homodimeric domain of signal transducing histidine kinase 11
Homeodomain-like DNA-glycosylase 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11

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