SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in uncultured Sulfuricurvum sp. RIFRC-1

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

517 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 3514
Nucleotide cyclase EAL domain-like 2914
PYP-like sensor domain (PAS domain) Nucleotide cyclase 2417
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 158
PYP-like sensor domain (PAS domain) EAL domain-like 1410
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 1310
CheY-like C-terminal effector domain of the bipartite response regulators 112
Actin-like ATPase domain Actin-like ATPase domain 94
CheY-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 87
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 83
CheY-like Homodimeric domain of signal transducing histidine kinase 87
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 76
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 75
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 76
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 63
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 63
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 64
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 63
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 63
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 63
P-loop containing nucleoside triphosphate hydrolases Translation proteins 65
Cytochrome c Cytochrome c 52
CBS-domain pair Nucleotide cyclase 55
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 53
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 52
Sensory domain-like Nucleotide cyclase 54
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 53
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 52
PurM N-terminal domain-like PurM C-terminal domain-like 52
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 52
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 41
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
Periplasmic binding protein-like II Periplasmic binding protein-like II 42
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 41
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 41
Calcium ATPase, transduction domain A HAD-like 43
CheY-like PYP-like sensor domain (PAS domain) 44
PLP-binding barrel Alanine racemase C-terminal domain-like 42
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 41
EAL domain-like HD-domain/PDEase-like 41
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 43
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 41
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 42
beta-Roll CalX-like 44
HAD-like Calcium ATPase, transmembrane domain M 43
PreATP-grasp domain Rudiment single hybrid motif 42
FAD/NAD(P)-binding domain HI0933 insert domain-like 41
CBS-domain pair CBS-domain pair 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
GAF domain-like HD-domain/PDEase-like 33
CheY-like Histidine-containing phosphotransfer domain, HPT domain 33
PYP-like sensor domain (PAS domain) GAF domain-like 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 32
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 32
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 31
EAL domain-like CBS-domain pair 33
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
cAMP-binding domain-like "Winged helix" DNA-binding domain 31
Periplasmic binding protein-like II Nucleotide cyclase 32
CheW-like CheY-like 32
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 32
Formyltransferase FMT C-terminal domain-like 32
CalX-like CalX-like 33
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 32
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 32
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 32
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Nucleic acid-binding proteins RuvA domain 2-like 33
PYP-like sensor domain (PAS domain) HD-domain/PDEase-like 33
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
CheY-like HD-domain/PDEase-like 22
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 22
Sensory domain-like PYP-like sensor domain (PAS domain) 22
CheC-like Surface presentation of antigens (SPOA) 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Aldolase post-HMGL domain-like 22
FliG FliG 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 21
MoeA N-terminal region -like MoeA C-terminal domain-like 21
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 22
ACT-like ACT-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 22
HAMP domain-like PYP-like sensor domain (PAS domain) 22
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 21
CBS-domain pair PYP-like sensor domain (PAS domain) 22
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 21
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 22
CheY-like EAL domain-like 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 21
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 21
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 22
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 21
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 21
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 22
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 21
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 21
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 22
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 21
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
Aldolase AFP III-like domain 21
TT1751-like TT1751-like 21
Sensory domain-like EAL domain-like 22
2Fe-2S ferredoxin-like alpha-helical ferredoxin 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
CheY-like Nucleotide cyclase 22
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 22
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 21
L30e-like alpha/beta knot 21
HAMP domain-like Nucleotide cyclase 22
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 22
Alpha-L RNA-binding motif Pseudouridine synthase 21
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 21
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 21
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 21
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 21
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 21
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 21
PDZ domain-like ClpP/crotonase 22
SufE/NifU Fe-S cluster assembly (FSCA) domain-like 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 21
alpha-helical ferredoxin Nucleotide-binding domain 22
TPR-like TPR-like 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
Translation proteins EF-G C-terminal domain-like 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 21
Nucleotidyltransferase ACT-like 22
Thioredoxin-like Six-hairpin glycosidases 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Nucleic acid-binding proteins Nucleic acid-binding proteins 22
TSP type-3 repeat OmpA-like 22
CheY-like CheY-like 22
Macro domain-like Zn-dependent exopeptidases 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 22
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
beta-Roll beta-Roll 11
TGS-like ACT-like 11
Rubredoxin-like Ferritin-like 11
PPK N-terminal domain-like PHP14-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
TTHA1013/TTHA0281-like Fe-S cluster assembly (FSCA) domain-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Tex N-terminal region-like RuvA domain 2-like 11
ACT-like Formyltransferase 11
OMPA-like TSP type-3 repeat 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
cAMP-binding domain-like CBS-domain pair 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
FMT C-terminal domain-like ClpP/crotonase 11
MOP-like MOP-like 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
HCP-like Fe-S cluster assembly (FSCA) domain-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Nucleotide-diphospho-sugar transferases Phosphoglucomutase, C-terminal domain 11
HD-domain/PDEase-like Nucleotide cyclase 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
HD-domain/PDEase-like ACT-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Rubredoxin-like Rubredoxin-like 11
Translation proteins ThrRS/AlaRS common domain 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases DNA methylase specificity domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Nucleotidyltransferase substrate binding subunit/domain Poly A polymerase C-terminal region-like 11
Fic-like "Winged helix" DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
MgtE N-terminal domain-like CBS-domain pair 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
CBS-domain pair Nucleotide-diphospho-sugar transferases 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
PUA domain-like Nucleotidylyl transferase 11
vWA-like TPR-like 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
Homodimeric domain of signal transducing histidine kinase EAL domain-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
HAMP domain-like HD-domain/PDEase-like 11
Ribonuclease H-like DNA/RNA polymerases 11
CheY-like P-loop containing nucleoside triphosphate hydrolases 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Lysozyme-like LysM domain 11
Trimeric LpxA-like enzymes Phosphoglucomutase, first 3 domains 11
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 11
L,D-transpeptidase catalytic domain-like NTF2-like 11
SpoIIaa-like cAMP-binding domain-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Ferredoxin thioredoxin reductase (FTR), catalytic beta chain Rhodanese/Cell cycle control phosphatase 11
Trypsin-like serine proteases Type III secretory system chaperone-like 11
4Fe-4S ferredoxins 4Fe-4S ferredoxins 11
Trypsin-like serine proteases PDZ domain-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
Nucleic acid-binding proteins BRCT domain 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Trigger factor ribosome-binding domain FKBP-like 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
CBS-domain pair MgtE membrane domain-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
post-HMGL domain-like Single hybrid motif 11
Radical SAM enzymes Nitrogenase accessory factor-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
DNA-glycosylase Nudix 11
NAD(P)-binding Rossmann-fold domains Citrate synthase 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
GAF domain-like EAL domain-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
PreATP-grasp domain PreATP-grasp domain 11
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
GAF domain-like Homeodomain-like 11
Nqo1C-terminal domain-like Nucleotide-binding domain 11
RuvA domain 2-like RuvA domain 2-like 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Ribosomal protein L6 Ribosomal protein L6 11
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
HisI-like all-alpha NTP pyrophosphatases 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
CheY-like GAF domain-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Nucleotide-binding domain Nucleotide-binding domain 11
HMA, heavy metal-associated domain HAD-like 11
UbiD C-terminal domain-like UbiD C-terminal domain-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Porins Porins 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
Actin-like ATPase domain HD-domain/PDEase-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
Homodimeric domain of signal transducing histidine kinase Nucleotide cyclase 11
Chorismate mutase II Periplasmic binding protein-like II 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Nqo1C-terminal domain-like alpha-helical ferredoxin 11
TTHA1013/TTHA0281-like Ribbon-helix-helix 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Nucleotide cyclase 11
OMPA-like OmpA-like 11
HIT-like HIT-like 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
Sec-C motif NTF2-like 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
PHP14-like Phospholipase D/nuclease 11
LeuD/IlvD-like Aconitase iron-sulfur domain 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
HD-domain/PDEase-like Nucleotidyltransferase 11
Aldolase Single hybrid motif 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
Class II aaRS and biotin synthetases Translation proteins 11
YajQ-like YajQ-like 11
YVTN repeat-like/Quinoprotein amine dehydrogenase C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
GAF domain-like Nucleotide cyclase 11
Periplasmic binding protein-like II PYP-like sensor domain (PAS domain) 11
Homocysteine S-methyltransferase Methionine synthase domain 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
PDZ domain-like PDZ domain-like 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
Chorismate mutase II ACT-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Phospholipase D/nuclease Phospholipase D/nuclease 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
Fibronectin type III Fibronectin type III 11
Rhodanese/Cell cycle control phosphatase P-loop containing nucleoside triphosphate hydrolases 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
HD-domain/PDEase-like TGS-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Translation proteins Translation proteins 11
Oxidoreductase molybdopterin-binding domain E set domains 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Nucleic acid-binding proteins GAD domain-like 11
"Winged helix" DNA-binding domain HRDC-like 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
PIN domain-like Ribonuclease H-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 11
YjeF N-terminal domain-like Ribokinase-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
vWA-like beta-Roll 11
Flagellar hook protein flgE Flagellar hook protein flgE 11
Thiamin diphosphate-binding fold (THDP-binding) 4Fe-4S ferredoxins 11
Serine metabolism enzymes domain ACT-like 11
GroEL-intermediate domain like GroEL apical domain-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
FKBP-like Triger factor/SurA peptide-binding domain-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
PIN domain-like DNA/RNA polymerases 11
P-loop containing nucleoside triphosphate hydrolases S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
DNA methylase specificity domain DNA methylase specificity domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Ribonuclease H-like RuvA domain 2-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
FMN-dependent nitroreductase-like FMN-dependent nitroreductase-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Glycerol-3-phosphate (1)-acyltransferase Acetyl-CoA synthetase-like 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
GroEL equatorial domain-like GroEL apical domain-like 11
Zinc beta-ribbon DNA primase core 11
(Trans)glycosidases Glycosyl hydrolase domain 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Ribokinase-like Nucleotidylyl transferase 11
Transposase IS200-like Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
TTHA1013/TTHA0281-like HCP-like 11
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 11
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 11
CarD-like TRCF domain-like 11
FAD/NAD(P)-binding domain HydA/Nqo6-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Periplasmic binding protein-like II ACT-like 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase tRNA-binding arm 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Thiolase-like Thiolase-like 11
Nucleotide-diphospho-sugar transferases Phosphoglucomutase, first 3 domains 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
alpha-helical ferredoxin alpha-helical ferredoxin 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
PK beta-barrel domain-like PK C-terminal domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase EAL domain-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 4Fe-4S ferredoxins 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
DNA clamp DNA clamp 11
Glycoside hydrolase/deacetylase Galactose mutarotase-like 11
RuvA domain 2-like BRCT domain 11
Class II aaRS and biotin synthetases GAD domain-like 11
Trimeric LpxA-like enzymes Phosphoglucomutase, C-terminal domain 11
Cupredoxins Cupredoxins 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Zinc beta-ribbon Zinc beta-ribbon 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Formyltransferase ClpP/crotonase 11
Glycerol-3-phosphate (1)-acyltransferase Acyl-CoA N-acyltransferases (Nat) 11
ITPase-like P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 11
beta and beta-prime subunits of DNA dependent RNA-polymerase beta and beta-prime subunits of DNA dependent RNA-polymerase 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Nucleotidyltransferase TGS-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
beta-Roll Concanavalin A-like lectins/glucanases 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
RNase III domain-like dsRNA-binding domain-like 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 11
Tex N-terminal region-like Ribonuclease H-like 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
CalX-like vWA-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
"Winged helix" DNA-binding domain MOP-like 11
Barwin-like endoglucanases Sporulation related repeat 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
HAMP domain-like EAL domain-like 11
TK C-terminal domain-like 4Fe-4S ferredoxins 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
GIY-YIG endonuclease RuvA domain 2-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Carbamate kinase-like ACT-like 11
YrdC/RibB RibA-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Poly A polymerase C-terminal region-like ACT-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Protein kinase-like (PK-like) HCP-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 11
PHP domain-like AF1531-like 11
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11

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