SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Brucella abortus S19

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

552 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2811
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 201
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 203
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 178
P-loop containing nucleoside triphosphate hydrolases MOP-like 161
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 144
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 141
Actin-like ATPase domain Actin-like ATPase domain 136
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 137
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 125
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 112
CheY-like C-terminal effector domain of the bipartite response regulators 112
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 105
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 102
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 103
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 94
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 91
Thiolase-like Thiolase-like 81
"Winged helix" DNA-binding domain GAF domain-like 81
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 83
GroES-like NAD(P)-binding Rossmann-fold domains 72
Thioredoxin-like GST C-terminal domain-like 71
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 74
P-loop containing nucleoside triphosphate hydrolases Translation proteins 76
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 74
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 76
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 76
PreATP-grasp domain Rudiment single hybrid motif 63
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 61
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 64
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 63
cAMP-binding domain-like "Winged helix" DNA-binding domain 61
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 63
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 52
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 52
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 54
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 52
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 53
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 52
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 52
"Winged helix" DNA-binding domain Chorismate lyase-like 51
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 44
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 41
Single hybrid motif CoA-dependent acyltransferases 42
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 44
HAD-like Calcium ATPase, transmembrane domain M 43
Triger factor/SurA peptide-binding domain-like FKBP-like 44
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 42
Enolase N-terminal domain-like Enolase C-terminal domain-like 41
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 41
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 42
PLP-binding barrel Alanine racemase C-terminal domain-like 41
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 41
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 41
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 42
Calcium ATPase, transduction domain A HAD-like 43
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 43
Nucleic acid-binding proteins Nucleic acid-binding proteins 44
MetI-like MetI-like 42
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 31
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 32
Pectin lyase-like Pectin lyase-like 33
CheY-like Homeodomain-like 31
PreATP-grasp domain Single hybrid motif 32
CBS-domain pair FAD-binding/transporter-associated domain-like 31
Homeodomain-like Homeodomain-like 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 32
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 31
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 31
Lysozyme-like PGBD-like 31
PDZ domain-like PDZ domain-like 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Pectin lyase-like Autotransporter 33
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 31
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
L30e-like alpha/beta knot 31
Rudiment single hybrid motif Single hybrid motif 32
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 32
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 32
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
Alpha-L RNA-binding motif Pseudouridine synthase 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 32
NAD(P)-binding Rossmann-fold domains ACT-like 33
Glutathione synthetase ATP-binding domain-like Single hybrid motif 32
Translation proteins EF-G C-terminal domain-like 33
HMA, heavy metal-associated domain HAD-like 32
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 31
CheY-like P-loop containing nucleoside triphosphate hydrolases 31
Homeodomain-like SIS domain 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 31
Trypsin-like serine proteases PDZ domain-like 33
ACT-like ACT-like 33
Lysozyme-like beta-lactamase/transpeptidase-like 33
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 33
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 31
Nucleotide cyclase EAL domain-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 22
Cytochrome c Cytochrome c 21
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 21
FAD/NAD(P)-binding domain HI0933 insert domain-like 21
MFS general substrate transporter MFS general substrate transporter 22
PYP-like sensor domain (PAS domain) Nucleotide cyclase 22
HlyD-like secretion proteins HlyD-like secretion proteins 22
alpha-helical ferredoxin Nucleotide-binding domain 21
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
ClpP/crotonase ClpP/crotonase 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 22
beta-lactamase/transpeptidase-like Sporulation related repeat 22
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 22
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 22
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 22
TrkA C-terminal domain-like TrkA C-terminal domain-like 22
GroES-like GroES-like 21
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 21
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 22
PYP-like sensor domain (PAS domain) CheY-like 22
Nucleotidyltransferase ACT-like 22
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
TPR-like TPR-like 22
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 21
Nucleotide-binding domain Nucleotide-binding domain 21
Aldolase post-HMGL domain-like 22
Translation proteins ThrRS/AlaRS common domain 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Cupredoxins Cupredoxins 22
Class I glutamine amidotransferase-like Homeodomain-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 22
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 21
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 22
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
RmlC-like cupins Homeodomain-like 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
Ribosomal protein S5 domain 2-like EF-G C-terminal domain-like 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
PYP-like sensor domain (PAS domain) EAL domain-like 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 22
Nucleotide-diphospho-sugar transferases RmlC-like cupins 21
PurM N-terminal domain-like PurM C-terminal domain-like 22
lambda repressor-like DNA-binding domains RmlC-like cupins 22
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 22
Homodimeric domain of signal transducing histidine kinase CheY-like 22
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 21
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
Phospholipase D/nuclease Phospholipase D/nuclease 22
Nucleic acid-binding proteins RuvA domain 2-like 22
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
NAD(P)-binding Rossmann-fold domains MurD-like peptide ligases, catalytic domain 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Carbamate kinase-like PUA domain-like 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
alpha-helical ferredoxin ARM repeat 11
Zinc beta-ribbon DNA primase core 11
D-aminopeptidase, middle and C-terminal domains D-aminopeptidase, middle and C-terminal domains 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Glutathione synthetase ATP-binding domain-like post-HMGL domain-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Thioredoxin-like TPR-like 11
CheY-like Nucleotide cyclase 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Serine metabolism enzymes domain ACT-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
PIN domain-like Ribonuclease H-like 11
Nucleic acid-binding proteins GAD domain-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Duplicated hybrid motif PLP-dependent transferases 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
HCP-like PGBD-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
ADC synthase Class I glutamine amidotransferase-like 11
PPK N-terminal domain-like PHP14-like 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Aldolase Single hybrid motif 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
SIS domain CBS-domain pair 11
GAF domain-like Homeodomain-like 11
GroEL-intermediate domain like GroEL apical domain-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
HRDC-like HRDC-like 11
CBS-domain pair MgtE membrane domain-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Tropomyosin PGBD-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
PreATP-grasp domain post-HMGL domain-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
PGBD-like PGBD-like 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
TGS-like ACT-like 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
TerB-like Chaperone J-domain 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Glutathione synthetase ATP-binding domain-like Aldolase 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
NAD(P)-binding Rossmann-fold domains MurD-like peptide ligases, peptide-binding domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 11
"Winged helix" DNA-binding domain PLP-dependent transferases 11
HD-domain/PDEase-like Nucleotidyltransferase 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
PLP-dependent transferases PLP-dependent transferases 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
TGS-like Class II aaRS ABD-related 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
Nucleotidylyl transferase Riboflavin kinase-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Cytochrome c Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Translation proteins Translation proteins 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
post-HMGL domain-like Single hybrid motif 11
RmlC-like cupins S-adenosyl-L-methionine-dependent methyltransferases 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Ribosomal protein L6 Ribosomal protein L6 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
Formyltransferase FMT C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Methionine synthase domain Methionine synthase activation domain-like 11
RuvA domain 2-like BRCT domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Nucleic acid-binding proteins PheT/TilS domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Dihydropteroate synthetase-like Methionine synthase domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Protein kinase-like (PK-like) 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Single hybrid motif alpha/beta-Hydrolases 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Ribonuclease H-like HRDC-like 11
PHP domain-like AF1531-like 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
HD-domain/PDEase-like ACT-like 11
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
PreATP-grasp domain PreATP-grasp domain 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
Nucleotidylyl transferase tRNA-binding arm 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Rudiment single hybrid motif post-HMGL domain-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Nucleotidyltransferase Nucleotidyltransferase 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Protein kinase-like (PK-like) PLP-dependent transferases 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Protein kinase-like (PK-like) Duplicated hybrid motif 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Translation proteins PRC-barrel domain 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 11
ACT-like Formyltransferase 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
DNA methylase specificity domain DNA methylase specificity domain 11
Periplasmic binding protein-like II Periplasmic binding protein-like II 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Trigger factor ribosome-binding domain FKBP-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Poly A polymerase C-terminal region-like ACT-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
ISP domain Bet v1-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
PIN domain-like DNA/RNA polymerases 11
Nitrous oxide reductase, N-terminal domain Cupredoxins 11
Rudiment single hybrid motif Aldolase 11
Periplasmic binding protein-like II ACT-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
dUTPase-like dUTPase-like 11
lambda repressor-like DNA-binding domains S-adenosyl-L-methionine-dependent methyltransferases 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
Glycoside hydrolase/deacetylase UraD-Like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Xylose isomerase-like NagB/RpiA/CoA transferase-like 11
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 11
Hsp33 domain HSP33 redox switch-like 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
PGBD-like L,D-transpeptidase catalytic domain-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Galactose mutarotase-like Galactose mutarotase-like 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Clc chloride channel CBS-domain pair 11
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Thioredoxin-like Six-hairpin glycosidases 11
PspA lactotransferrin-binding region OmpA-like 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
lambda repressor-like DNA-binding domains PUA domain-like 11
Galactose mutarotase-like Six-hairpin glycosidases 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
alpha/beta-Hydrolases alpha/beta-Hydrolases 11
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 11
FAD/NAD(P)-binding domain Nucleotide cyclase 11
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 11
Single hybrid motif Thiamin diphosphate-binding fold (THDP-binding) 11
FMN-linked oxidoreductases 4Fe-4S ferredoxins 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
PUA domain-like alpha/beta knot 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Tropomyosin HCP-like 11
YrdC/RibB RibA-like 11
Nucleotidyltransferase TGS-like 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
beta-lactamase/transpeptidase-like D-aminopeptidase, middle and C-terminal domains 11
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 11
CoA-dependent acyltransferases CoA-dependent acyltransferases 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
Class II aaRS and biotin synthetases Translation proteins 11
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 11
Adhesin YadA, collagen-binding domain Pili subunits 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
GAF domain-like Nucleotide cyclase 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
PreATP-grasp domain Aldolase 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
PheT/TilS domain Putative DNA-binding domain 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Class II aaRS and biotin synthetases GAD domain-like 11
Bacterial muramidases Lysozyme-like 11
TGS-like ThrRS/AlaRS common domain 11
RuvA domain 2-like JAB1/MPN domain 11
GAF domain-like Phosphohistidine domain 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex alpha/beta-Hydrolases 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
CarD-like TRCF domain-like 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
TGS-like Class II aaRS and biotin synthetases 11
Nucleotidyltransferase substrate binding subunit/domain Poly A polymerase C-terminal region-like 11
PDZ domain-like ClpP/crotonase 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
RNase III domain-like dsRNA-binding domain-like 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
YjeF N-terminal domain-like Ribokinase-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Ribonuclease H-like DNA/RNA polymerases 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
Nucleic acid-binding proteins BRCT domain 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
PRC-barrel domain PRC-barrel domain 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Isochorismatase-like hydrolases ACP-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
HD-domain/PDEase-like TGS-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
CbiG N-terminal domain-like Tetrapyrrole methylase 11
PreATP-grasp domain Methylglyoxal synthase-like 11
DNA-glycosylase Nudix 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Apolipoprotein A-I Apolipoprotein A-I 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
YebC-like PFL-like glycyl radical enzymes 11
TPR-like S-adenosyl-L-methionine-dependent methyltransferases 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
CheY-like CheY-like 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
Ribbon-helix-helix ACT-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Macro domain-like Zn-dependent exopeptidases 11
Homocysteine S-methyltransferase Methionine synthase domain 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 11
PHP14-like Phospholipase D/nuclease 11
YlxR-like L30e-like 11
DNA clamp DNA clamp 11
Ribulose-phoshate binding barrel Actin-like ATPase domain 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Adhesin YadA, collagen-binding domain Adhesin YadA, collagen-binding domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Single hybrid motif TK C-terminal domain-like 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
FAD-linked oxidoreductase ALDH-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
MgtE N-terminal domain-like CBS-domain pair 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Carbamate kinase-like ACT-like 11

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