SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Burkholderia phymatum STM815

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

885 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 1572
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 6433
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 4917
Homeodomain-like Homeodomain-like 467
CheY-like C-terminal effector domain of the bipartite response regulators 413
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 357
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 3325
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 333
GroES-like NAD(P)-binding Rossmann-fold domains 322
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 303
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 306
P-loop containing nucleoside triphosphate hydrolases MOP-like 282
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 268
Homodimeric domain of signal transducing histidine kinase CheY-like 2620
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 2621
"Winged helix" DNA-binding domain GAF domain-like 251
"Winged helix" DNA-binding domain PLP-dependent transferases 241
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 243
Class I glutamine amidotransferase-like Homeodomain-like 243
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 2212
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 224
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 211
Actin-like ATPase domain Actin-like ATPase domain 206
Thioredoxin-like GST C-terminal domain-like 201
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 2017
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 197
Nucleotide cyclase EAL domain-like 189
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 185
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 189
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 173
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 1715
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 177
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 161
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 166
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 166
PYP-like sensor domain (PAS domain) Nucleotide cyclase 169
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 166
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 166
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 166
PYP-like sensor domain (PAS domain) CheY-like 1512
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 141
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 143
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 141
Cytochrome c Cytochrome c 145
Thiolase-like Thiolase-like 142
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 135
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 135
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 133
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 123
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1211
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 124
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 114
ISP domain Bet v1-like 112
P-loop containing nucleoside triphosphate hydrolases Translation proteins 116
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 104
"Winged helix" DNA-binding domain Chorismate lyase-like 101
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 101
CheY-like CheY-like 109
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 101
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 105
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 106
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 105
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 107
PYP-like sensor domain (PAS domain) EAL domain-like 105
Enolase N-terminal domain-like Enolase C-terminal domain-like 91
Homeodomain-like SIS domain 93
Phage tail proteins Phage tail proteins 94
TPR-like TPR-like 96
P-loop containing nucleoside triphosphate hydrolases CheY-like 95
lambda repressor-like DNA-binding domains RmlC-like cupins 91
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 84
Phage tail proteins gp5 N-terminal domain-like 83
CheY-like Homeodomain-like 84
gp5 N-terminal domain-like Phage fibre proteins 83
(Trans)glycosidases Glycosyl hydrolase domain 86
GAF domain-like Homodimeric domain of signal transducing histidine kinase 87
Phage tail proteins Phage fibre proteins 83
PurM N-terminal domain-like PurM C-terminal domain-like 72
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 75
Phospholipase D/nuclease Phospholipase D/nuclease 75
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 71
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 75
GAF domain-like CheY-like 76
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 73
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 71
Homeodomain-like Ribonuclease H-like 72
GAF domain-like Homeodomain-like 74
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 71
RmlC-like cupins Homeodomain-like 72
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 64
Adhesin YadA, collagen-binding domain Adhesin YadA, collagen-binding domain 66
Aspartate receptor, ligand-binding domain Methyl-accepting chemotaxis protein (MCP) signaling domain 63
Acetyl-CoA synthetase-like ACP-like 66
GAF domain-like PYP-like sensor domain (PAS domain) 66
Translation proteins EF-G C-terminal domain-like 63
HAD-like Calcium ATPase, transmembrane domain M 64
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 63
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 65
HlyD-like secretion proteins HlyD-like secretion proteins 64
Regulatory protein AraC Homeodomain-like 62
PreATP-grasp domain Rudiment single hybrid motif 63
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 64
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 66
Adhesin YadA, collagen-binding domain Pili subunits 66
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 63
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 63
Calcium ATPase, transduction domain A HAD-like 64
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 64
FKBP-like Triger factor/SurA peptide-binding domain-like 64
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 63
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 64
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 62
Folate-binding domain Aminomethyltransferase beta-barrel domain 63
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 54
LeuD/IlvD-like Aconitase iron-sulfur domain 53
C-terminal effector domain of the bipartite response regulators P-loop containing nucleoside triphosphate hydrolases 53
E set domains (Trans)glycosidases 53
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 54
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 53
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 51
Lysozyme-like beta-lactamase/transpeptidase-like 53
GAF domain-like Nucleotide cyclase 55
Trypsin-like serine proteases PDZ domain-like 53
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 51
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 52
EF-G C-terminal domain-like EF-G C-terminal domain-like 52
CoA-dependent acyltransferases CoA-dependent acyltransferases 55
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 53
Nucleotide-diphospho-sugar transferases RmlC-like cupins 51
Alpha-L RNA-binding motif Pseudouridine synthase 53
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 42
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 42
E set domains Glycosyl hydrolase domain 42
cAMP-binding domain-like "Winged helix" DNA-binding domain 42
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 42
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 42
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 41
PYP-like sensor domain (PAS domain) Homeodomain-like 44
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 42
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 42
ParB/Sulfiredoxin KorB DNA-binding domain-like 41
CheY-like Histidine-containing phosphotransfer domain, HPT domain 44
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 43
Single hybrid motif CoA-dependent acyltransferases 42
cAMP-binding domain-like FAD/NAD(P)-binding domain 41
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 43
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 42
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 43
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 44
CoA-dependent acyltransferases ACP-like 44
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 41
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 43
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 44
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 41
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 42
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 41
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 42
EAL domain-like Sensory domain-like 42
Aspartate/glutamate racemase Aspartate/glutamate racemase 42
CoA-dependent acyltransferases Acetyl-CoA synthetase-like 44
P-loop containing nucleoside triphosphate hydrolases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
PDZ domain-like PDZ domain-like 42
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
6-phosphogluconate dehydrogenase C-terminal domain-like ClpP/crotonase 32
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
HD-domain/PDEase-like ACT-like 32
Nucleotide cyclase Sensory domain-like 33
Nucleic acid-binding proteins RuvA domain 2-like 33
CBS-domain pair FAD-binding/transporter-associated domain-like 32
H-NS histone-like proteins H-NS histone-like proteins 32
FAD/NAD(P)-binding domain Thioredoxin-like 33
ACT-like ACT-like 33
ACT-like Formyltransferase 31
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 32
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 33
Aldolase post-HMGL domain-like 32
NAD(P)-binding Rossmann-fold domains ClpP/crotonase 32
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 32
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 33
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 32
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
FAD/NAD(P)-binding domain Folate-binding domain 32
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 33
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 32
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
P-loop containing nucleoside triphosphate hydrolases TPR-like 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 32
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 31
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 31
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 31
ClpP/crotonase ClpP/crotonase 31
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 32
LysM domain Duplicated hybrid motif 32
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 33
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 33
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 32
Nucleotidyltransferase ACT-like 32
Translation proteins Ribosomal protein S5 domain 2-like 31
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 33
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 32
HD-domain/PDEase-like Nucleotidyltransferase 32
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
ACP-like ACP-like 33
CheY-like Methylesterase CheB, C-terminal domain 32
Nqo1 middle domain-like Nqo1C-terminal domain-like 22
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 21
L30e-like alpha/beta knot 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 22
Protein kinase-like (PK-like) GAF domain-like 22
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 21
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 22
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
Formylmethanofuran:tetrahydromethanopterin formyltransferase Formylmethanofuran:tetrahydromethanopterin formyltransferase 21
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
LysM domain Lysozyme-like 22
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
HAMP domain-like PYP-like sensor domain (PAS domain) 22
MetI-like MetI-like 21
Nucleotidyltransferase TGS-like 21
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 21
Duplicated hybrid motif Lysozyme-like 22
Translation proteins ThrRS/AlaRS common domain 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 22
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 21
cAMP-binding domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Acylphosphatase/BLUF domain-like YrdC/RibB 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 21
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 22
Ribonuclease H-like DNA/RNA polymerases 22
SAM/Pointed domain Nucleotide cyclase 22
SAM/Pointed domain P-loop containing nucleoside triphosphate hydrolases 22
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 22
alpha-helical ferredoxin Nucleotide-binding domain 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 21
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 21
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 22
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 21
MetI-like P-loop containing nucleoside triphosphate hydrolases 21
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 21
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 21
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 21
Acetyl-CoA synthetase-like Acetyl-CoA synthetase-like 22
GAF domain-like GAF domain-like 22
GAF domain-like EAL domain-like 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
Nucleotide cyclase TPR-like 22
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 21
HD-domain/PDEase-like TGS-like 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 22
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
FAD/NAD(P)-binding domain HI0933 insert domain-like 21
ACP-like PLP-dependent transferases 22
Resolvase-like Homeodomain-like 21
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 21
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 21
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 21
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 22
CoA-transferase family III (CaiB/BaiF) CoA-transferase family III (CaiB/BaiF) 21
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 21
UDP-Glycosyltransferase/glycogen phosphorylase Nucleotide-diphospho-sugar transferases 22
Nucleotide cyclase P-loop containing nucleoside triphosphate hydrolases 22
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
CheW-like CheY-like 22
Single hybrid motif Single hybrid motif 22
Rudiment single hybrid motif Single hybrid motif 22
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
ACP-like NAD(P)-binding Rossmann-fold domains 22
GroEL equatorial domain-like GroEL apical domain-like 21
Protein kinase-like (PK-like) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 22
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 22
Protease propeptides/inhibitors Subtilisin-like 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
PreATP-grasp domain Single hybrid motif 22
Nucleotide-diphospho-sugar transferases PilZ domain-like 21
HAMP domain-like Nucleotide cyclase 22
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 22
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 22
Galactose-binding domain-like Galactose-binding domain-like 21
Methylesterase CheB, C-terminal domain Chemotaxis receptor methyltransferase CheR, N-terminal domain 22
GroEL-intermediate domain like GroEL apical domain-like 21
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 21
PH0987 N-terminal domain-like Cyclophilin-like 22
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 22
Glutathione synthetase ATP-binding domain-like Single hybrid motif 22
FMN-binding split barrel UbiD C-terminal domain-like 22
TGS-like ACT-like 21
MOP-like MOP-like 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 22
PLP-binding barrel Alanine racemase C-terminal domain-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
EAL domain-like HD-domain/PDEase-like 21
Formyltransferase FMT C-terminal domain-like 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Clc chloride channel CBS-domain pair 21
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 21
Cupredoxins Cytochrome c 22
Methylesterase CheB, C-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 22
Histidine-containing phosphotransfer domain, HPT domain CheW-like 22
2Fe-2S ferredoxin-like alpha-helical ferredoxin 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
GroEL equatorial domain-like GroEL-intermediate domain like 21
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 22
MoeA N-terminal region -like MoeA C-terminal domain-like 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 21
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 21
GroES-like GroES-like 21
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
Thioredoxin-like Nqo1C-terminal domain-like 11
Ribonuclease H-like Nucleic acid-binding proteins 11
PreATP-grasp domain PreATP-grasp domain 11
Phase 1 flagellin Phase 1 flagellin 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes Acyl-CoA N-acyltransferases (Nat) 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Chorismate mutase II Periplasmic binding protein-like II 11
Molybdenum cofactor-binding domain Bet v1-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
C-terminal effector domain of the bipartite response regulators cAMP-binding domain-like 11
HAMP domain-like GAF domain-like 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
FMN-linked oxidoreductases 4Fe-4S ferredoxins 11
YajQ-like YajQ-like 11
Nucleic acid-binding proteins GAD domain-like 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 11
Periplasmic binding protein-like II Periplasmic binding protein-like II 11
PH0987 N-terminal domain-like Single hybrid motif 11
Thiolase-like PLP-dependent transferases 11
TATA-box binding protein-like DNA-glycosylase 11
Glutathione synthetase ATP-binding domain-like Cyclophilin-like 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Cupredoxins Cupredoxins 11
Thioredoxin-like Nqo1 FMN-binding domain-like 11
CoA-dependent acyltransferases NAD(P)-binding Rossmann-fold domains 11
PK beta-barrel domain-like PK C-terminal domain-like 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Rudiment single hybrid motif PH0987 N-terminal domain-like 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
HD-domain/PDEase-like C-terminal effector domain of the bipartite response regulators 11
RuBisCO, large subunit, small (N-terminal) domain RuBisCo, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
UROD/MetE-like UROD/MetE-like 11
Dimeric alpha+beta barrel Dimeric alpha+beta barrel 11
Ribbon-helix-helix N-terminal domain of bifunctional PutA protein 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
4Fe-4S ferredoxins ADC-like 11
Acetyl-CoA synthetase-like PLP-dependent transferases 11
GIY-YIG endonuclease RuvA domain 2-like 11
ACP-like Glycerol-3-phosphate (1)-acyltransferase 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Glucose permease domain IIB Glucose permease domain IIB 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Carbamate kinase-like PUA domain-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain Homodimeric domain of signal transducing histidine kinase 11
Cobalamin (vitamin B12)-binding domain P-loop containing nucleoside triphosphate hydrolases 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases GAD domain-like 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Methylesterase CheB, C-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
SpoIIaa-like cAMP-binding domain-like 11
CBS-domain pair Nucleotide cyclase 11
Zinc beta-ribbon DNA primase core 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors NTF2-like 11
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Ferredoxin reductase-like, C-terminal NADP-linked domain GntR ligand-binding domain-like 11
2Fe-2S ferredoxin-like 2Fe-2S ferredoxin-like 11
PPK N-terminal domain-like PHP14-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Actin-like ATPase domain Homeodomain-like 11
Oxidoreductase molybdopterin-binding domain E set domains 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
TGS-like ThrRS/AlaRS common domain 11
TTHA1013/TTHA0281-like lambda repressor-like DNA-binding domains 11
NagB/RpiA/CoA transferase-like 4Fe-4S ferredoxins 11
PLP-dependent transferases NAD(P)-binding Rossmann-fold domains 11
RuvA domain 2-like BRCT domain 11
E set domains E set domains 11
FliG FliG 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Flavoproteins 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Single hybrid motif alpha/beta-Hydrolases 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
MesJ substrate recognition domain-like PheT/TilS domain 11
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
Ricin B-like lectins Integrin alpha N-terminal domain 11
Flavoproteins Riboflavin synthase domain-like 11
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 11
FMN-binding split barrel Riboflavin synthase domain-like 11
FMN-linked oxidoreductases Nucleotide-binding domain 11
DNA topoisomerase I domain DNA breaking-rejoining enzymes 11
2-methylcitrate dehydratase PrpD 2-methylcitrate dehydratase PrpD 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
ACP-like alpha/beta-Hydrolases 11
Metallo-hydrolase/oxidoreductase Rhodanese/Cell cycle control phosphatase 11
Macro domain-like Zn-dependent exopeptidases 11
TGS-like Class II aaRS and biotin synthetases 11
Acetyl-CoA synthetase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Hsp33 domain HSP33 redox switch-like 11
FKBP-like FKBP-like 11
CbiG N-terminal domain-like Tetrapyrrole methylase 11
Cytochrome c oxidase subunit II-like, transmembrane region OmpA-like 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 11
Methylesterase CheB, C-terminal domain Homodimeric domain of signal transducing histidine kinase 11
Porins Porins 11
DNA-glycosylase Nudix 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Aldolase AFP III-like domain 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
Purple acid phosphatase, N-terminal domain Metallo-dependent phosphatases 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
UDP-Glycosyltransferase/glycogen phosphorylase S-adenosyl-L-methionine-dependent methyltransferases 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
PurS-like PurM C-terminal domain-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
RuvA domain 2-like RuvA domain 2-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
RmlC-like cupins RmlC-like cupins 11
alpha/beta-Hydrolases alpha/beta-Hydrolases 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
RmlC-like cupins Adenine nucleotide alpha hydrolases-like 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
YrdC/RibB RibA-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
PRC-barrel domain PRC-barrel domain 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Cobalamin (vitamin B12)-binding domain Radical SAM enzymes 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Riboflavin synthase domain-like Cytochrome P450 11
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 11
Pseudouridine synthase PUA domain-like 11
Rudiment single hybrid motif Cyclophilin-like 11
Nucleic acid-binding proteins BRCT domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Galactose mutarotase-like Glycosyl hydrolase domain 11
Ribbon-helix-helix FAD-linked oxidoreductase 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Ribonuclease H-like RuvA domain 2-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
2Fe-2S ferredoxin-like ADC-like 11
P-loop containing nucleoside triphosphate hydrolases Cobalamin (vitamin B12)-dependent enzymes 11
ABC transporter transmembrane region CheY-like 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Putative DNA-binding domain TPR-like 11
Acetyl-CoA synthetase-like FabD/lysophospholipase-like 11
PRTase-like PRTase-like 11
Caspase-like C-type lectin-like 11
4Fe-4S ferredoxins Respiratory nitrate reductase 1 gamma chain 11
RNase III domain-like dsRNA-binding domain-like 11
PreATP-grasp domain Cyclophilin-like 11
DNA clamp DNA clamp 11
Mechanosensitive channel protein MscS (YggB), C-terminal domain cAMP-binding domain-like 11
(Trans)glycosidases Class I glutamine amidotransferase-like 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
CoA-dependent acyltransferases alpha/beta-Hydrolases 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Methyl-accepting chemotaxis protein (MCP) signaling domain Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Periplasmic binding protein-like II Lysozyme-like 11
TPR-like Porins 11
CheC-like Surface presentation of antigens (SPOA) 11
Globin-like Riboflavin synthase domain-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Rhodanese/Cell cycle control phosphatase P-loop containing nucleoside triphosphate hydrolases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
HMA, heavy metal-associated domain HAD-like 11
FAD-linked reductases, C-terminal domain Thioredoxin-like 11
Family A G protein-coupled receptor-like CBS-domain pair 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
MFS general substrate transporter MFS general substrate transporter 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
alpha/beta-Hydrolases C-terminal effector domain of the bipartite response regulators 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain PYP-like sensor domain (PAS domain) 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
Nqo5-like HydB/Nqo4-like 11
ABC transporter involved in vitamin B12 uptake, BtuC ABC transporter involved in vitamin B12 uptake, BtuC 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain CheY-like 11
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
Duplicated hybrid motif HPr-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
FabD/lysophospholipase-like PLP-dependent transferases 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
JAB1/MPN domain Cysteine proteinases 11
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
(Trans)glycosidases Galactose-binding domain-like 11
Ferredoxin reductase-like, C-terminal NADP-linked domain Cytochrome P450 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
(Phosphotyrosine protein) phosphatases II FAD/NAD(P)-binding domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Class I glutamine amidotransferase-like Glycosyl hydrolase domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
PreATP-grasp domain Methylglyoxal synthase-like 11
FMN-dependent nitroreductase-like FMN-dependent nitroreductase-like 11
SMAD/FHA domain P-loop containing nucleoside triphosphate hydrolases 11
WD40 repeat-like TPR-like 11
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
FAD-linked reductases, C-terminal domain Aminomethyltransferase beta-barrel domain 11
Acetyl-CoA synthetase-like Thioesterase/thiol ester dehydrase-isomerase 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
Duplicated hybrid motif Phosphohistidine domain 11
Succinyl-CoA synthetase domains Citrate synthase 11
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Respiratory nitrate reductase 1 gamma chain alpha-helical ferredoxin 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Periplasmic binding protein-like I Homeodomain-like 11
YjeF N-terminal domain-like Ribokinase-like 11
(Trans)glycosidases (Trans)glycosidases 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
lambda repressor-like DNA-binding domains P-loop containing nucleoside triphosphate hydrolases 11
Sensory domain-like HAMP domain-like 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Methionine synthase domain Methionine synthase activation domain-like 11
4Fe-4S ferredoxins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Putative DNA-binding domain DNA-binding domain 11
Homeodomain-like Acetamidase/Formamidase-like 11
cAMP-binding domain-like ABC transporter transmembrane region 11
Methylesterase CheB, C-terminal domain PYP-like sensor domain (PAS domain) 11
FMN-binding split barrel 2Fe-2S ferredoxin-like 11
FAD/NAD(P)-binding domain NAD(P)-binding Rossmann-fold domains 11
Acetyl-CoA synthetase-like Glycerol-3-phosphate (1)-acyltransferase 11
GntR ligand-binding domain-like Cytochrome P450 11
HAMP domain-like EAL domain-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Protein kinase-like (PK-like) PYP-like sensor domain (PAS domain) 11
(Trans)glycosidases Glycoside hydrolase/deacetylase 11
4Fe-4S ferredoxins Cna protein B-type domain 11
Phosphoenolpyruvate/pyruvate domain Nucleotide-diphospho-sugar transferases 11
EAL domain-like CBS-domain pair 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Ribosomal protein L6 Ribosomal protein L6 11
Histidine-containing phosphotransfer domain, HPT domain CheY-binding domain of CheA 11
NAD(P)-binding Rossmann-fold domains Citrate synthase 11
P-loop containing nucleoside triphosphate hydrolases Adenine nucleotide alpha hydrolases-like 11
S-adenosyl-L-methionine-dependent methyltransferases CheY-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
HprK N-terminal domain-like PEP carboxykinase-like 11
Methyl-accepting chemotaxis protein (MCP) signaling domain GAF domain-like 11
PUA domain-like alpha/beta knot 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
PHP domain-like Nucleic acid-binding proteins 11
Carbamate kinase-like ACT-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
ALDH-like ALDH-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
CheY-like FAD/NAD(P)-binding domain 11
4Fe-4S ferredoxins Riboflavin synthase domain-like 11
Thioredoxin-like Nqo1 middle domain-like 11
PheT/TilS domain Putative DNA-binding domain 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
2Fe-2S ferredoxin-like Cytochrome P450 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Homeodomain-like TPR-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
L domain-like L domain-like 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase CoA-dependent acyltransferases 11
Acetyl-CoA synthetase-like Thiolase-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Translation proteins Translation proteins 11
CheY-binding domain of CheA Homodimeric domain of signal transducing histidine kinase 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Methyl-accepting chemotaxis protein (MCP) signaling domain CheY-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
FAD-linked reductases, C-terminal domain Folate-binding domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
cAMP-binding domain-like P-loop containing nucleoside triphosphate hydrolases 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Duplicated hybrid motif Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
ACP-like FabD/lysophospholipase-like 11
ATP-dependent DNA ligase DNA-binding domain Nucleic acid-binding proteins 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Thioredoxin-like TPR-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase PLP-dependent transferases 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
S-adenosyl-L-methionine-dependent methyltransferases PYP-like sensor domain (PAS domain) 11
Nucleic acid-binding proteins PheT/TilS domain 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
ABC transporter transmembrane region ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Thiolase-like FabD/lysophospholipase-like 11
MalF N-terminal region-like MetI-like 11
Cytochrome c oxidase subunit I-like Cytochrome c oxidase subunit III-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
PrpR receptor domain-like PYP-like sensor domain (PAS domain) 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
PurS-like FGAM synthase PurL, linker domain 11
"Winged helix" DNA-binding domain MOP-like 11
ACP-like Thiolase-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
PLP-dependent transferases PLP-dependent transferases 11
HPr-like Phosphohistidine domain 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Actin-like ATPase domain HD-domain/PDEase-like 11
PurS-like PurM N-terminal domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase PP2C-like 11
Single hybrid motif FAD/NAD(P)-binding domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
cAMP-binding domain-like cAMP-binding domain-like 11
Bacterial muramidases Lysozyme-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
CarD-like TRCF domain-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
PHP14-like Phospholipase D/nuclease 11
Cyclophilin-like Cyclophilin-like 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
FAD/NAD(P)-binding domain alpha/beta-Hydrolases 11
ISP domain FAD/NAD(P)-binding domain 11
LmbE-like Ricin B-like lectins 11
LigB-like LigA subunit of an aromatic-ring-opening dioxygenase LigAB 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Methyl-accepting chemotaxis protein (MCP) signaling domain Homodimeric domain of signal transducing histidine kinase 11
Translation proteins PRC-barrel domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Ribonuclease H-like GIY-YIG endonuclease 11
2Fe-2S ferredoxin-like GntR ligand-binding domain-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
ClpP/crotonase NfeD domain-like 11
Tex N-terminal region-like RuvA domain 2-like 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 11
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase Calcium-dependent phosphotriesterase 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
Riboflavin synthase domain-like GntR ligand-binding domain-like 11
P-loop containing nucleoside triphosphate hydrolases Homodimeric domain of signal transducing histidine kinase 11
Tex N-terminal region-like Ribonuclease H-like 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Periplasmic binding protein-like II CheY-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Acetyl-CoA synthetase-like NAD(P)-binding Rossmann-fold domains 11
SMAD/FHA domain SMAD/FHA domain 11
Voltage-gated potassium channels E set domains 11
CheY-binding domain of CheA CheW-like 11
Adenine nucleotide alpha hydrolases-like GAF domain-like 11
Family A G protein-coupled receptor-like FAD-binding/transporter-associated domain-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Cyclophilin-like Single hybrid motif 11
Ribbon-helix-helix ALDH-like 11
CO dehydrogenase molybdoprotein N-domain-like Bet v1-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
ADC-like Riboflavin synthase domain-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
PLP-dependent transferases CoA-dependent acyltransferases 11
Translation proteins "Winged helix" DNA-binding domain 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Chorismate mutase II ACT-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Radical SAM enzymes Nitrogenase accessory factor-like 11
Putative DNA-binding domain Translation proteins 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
S-adenosyl-L-methionine-dependent methyltransferases Homodimeric domain of signal transducing histidine kinase 11
S-adenosyl-L-methionine-dependent methyltransferases TPR-like 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
Periplasmic binding protein-like II PYP-like sensor domain (PAS domain) 11
C-terminal effector domain of the bipartite response regulators TPR-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Ferritin-like Calcium ATPase, transmembrane domain M 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
CheY-like Nucleotide cyclase 11
Sigma2 domain of RNA polymerase sigma factors NTF2-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Metalloproteases ("zincins"), catalytic domain PDZ domain-like 11
PurS-like Class I glutamine amidotransferase-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Methyl-accepting chemotaxis protein (MCP) signaling domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
HPr-like Phosphoenolpyruvate/pyruvate domain 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Homodimeric domain of signal transducing histidine kinase Homodimeric domain of signal transducing histidine kinase 11
Ferritin-like HAD-like 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
Glycosyl hydrolase domain Protein kinase-like (PK-like) 11
Tropomyosin P-loop containing nucleoside triphosphate hydrolases 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain "Winged helix" DNA-binding domain 11
CheY-binding domain of CheA ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
ADC-like Flavoproteins 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
PIN domain-like Ribonuclease H-like 11
Periplasmic binding protein-like II ACT-like 11
TGS-like Class II aaRS ABD-related 11
Glutathione synthetase ATP-binding domain-like PH0987 N-terminal domain-like 11
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
PrpR receptor domain-like P-loop containing nucleoside triphosphate hydrolases 11
PrpR receptor domain-like Homeodomain-like 11
Nucleotide-binding domain Nucleotide-binding domain 11
FAD-linked oxidoreductase ALDH-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
S-adenosyl-L-methionine-dependent methyltransferases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PreATP-grasp domain PH0987 N-terminal domain-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Cytochrome c OmpA-like 11
Galactose mutarotase-like (Trans)glycosidases 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Actin-like ATPase domain SIS domain 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
LmbE-like Integrin alpha N-terminal domain 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
ACP-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
CheY-like cAMP-binding domain-like 11
PIN domain-like DNA/RNA polymerases 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
ATP-dependent DNA ligase DNA-binding domain DNA ligase/mRNA capping enzyme, catalytic domain 11
Duplicated hybrid motif Phosphoenolpyruvate/pyruvate domain 11
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 11
FabD/lysophospholipase-like CoA-dependent acyltransferases 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Thiolase-like CoA-dependent acyltransferases 11
Thioredoxin-like Thioredoxin-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Riboflavin synthase domain-like 11
Periplasmic binding protein-like II Histidine-containing phosphotransfer domain, HPT domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Putative DNA-binding domain Citrate synthase 11
ADC-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
SAM/Pointed domain TPR-like 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Ferredoxin reductase-like, C-terminal NADP-linked domain 11
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Cupredoxins OmpA-like 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases ParB/Sulfiredoxin 11
ISP domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Sm-like ribonucleoproteins cAMP-binding domain-like 11
PDZ domain-like ClpP/crotonase 11
Nucleotidylyl transferase tRNA-binding arm 11
PilZ domain-like PilZ domain-like 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
FMN-binding split barrel Ferredoxin reductase-like, C-terminal NADP-linked domain 11
lambda repressor-like DNA-binding domains S-adenosyl-L-methionine-dependent methyltransferases 11
Periplasmic binding protein-like II Cytochrome c 11
Ferritin-like Calcium ATPase, transduction domain A 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Acetyl-CoA synthetase-like alpha/beta-Hydrolases 11
Radical SAM enzymes RuvA domain 2-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11

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