SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Legionella longbeachae NSW150

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

605 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2616
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 151
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1310
PYP-like sensor domain (PAS domain) Nucleotide cyclase 117
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 103
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 106
Calcium ATPase, transduction domain A HAD-like 93
Actin-like ATPase domain Actin-like ATPase domain 92
GroES-like NAD(P)-binding Rossmann-fold domains 93
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 93
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 94
HAD-like Calcium ATPase, transmembrane domain M 93
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 92
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 95
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 95
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 95
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 95
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 94
PYP-like sensor domain (PAS domain) CheY-like 97
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 95
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 82
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 88
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 77
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 74
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 73
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 74
Thioredoxin-like GST C-terminal domain-like 71
Thiolase-like Thiolase-like 72
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 71
P-loop containing nucleoside triphosphate hydrolases Translation proteins 75
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 65
Nucleotide cyclase EAL domain-like 64
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 66
Homodimeric domain of signal transducing histidine kinase CheY-like 66
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 64
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 64
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 64
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
PYP-like sensor domain (PAS domain) EAL domain-like 53
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 54
Thiolase-like ACP-like 55
CheY-like C-terminal effector domain of the bipartite response regulators 51
CheY-like Nucleotide cyclase 54
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 53
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 52
ACP-like CoA-dependent acyltransferases 44
Thiolase-like NAD(P)-binding Rossmann-fold domains 44
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 43
SpoIIaa-like cAMP-binding domain-like 42
CheY-like Histidine-containing phosphotransfer domain, HPT domain 44
Aconitase iron-sulfur domain LeuD/IlvD-like 42
EF-G C-terminal domain-like EF-G C-terminal domain-like 43
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 43
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 44
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 44
TPR-like TPR-like 43
Translation proteins EF-G C-terminal domain-like 43
PurM N-terminal domain-like PurM C-terminal domain-like 42
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 42
CoA-dependent acyltransferases CoA-dependent acyltransferases 44
Nucleotidyltransferase Poly A polymerase C-terminal region-like 43
ACP-like ACP-like 44
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 43
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 42
NAD(P)-binding Rossmann-fold domains ACP-like 44
ACP-like Acetyl-CoA synthetase-like 44
Thiolase-like Acetyl-CoA synthetase-like 33
Single hybrid motif CoA-dependent acyltransferases 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 33
CBS-domain pair FAD-binding/transporter-associated domain-like 31
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 32
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 31
Trypsin-like serine proteases PDZ domain-like 33
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
Alpha-L RNA-binding motif Pseudouridine synthase 31
GAF domain-like Nucleotide cyclase 32
CheY-like CheY-like 33
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 32
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 31
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 31
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 31
lambda repressor-like DNA-binding domains LexA/Signal peptidase 31
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 31
FKBP-like Triger factor/SurA peptide-binding domain-like 33
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 32
RuvA domain 2-like Nucleic acid-binding proteins 33
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 32
CoA-dependent acyltransferases Acetyl-CoA synthetase-like 33
Ankyrin repeat Ankyrin repeat 33
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 32
Thiolase-like FabD/lysophospholipase-like 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
PreATP-grasp domain Rudiment single hybrid motif 32
PLP-binding barrel Alanine racemase C-terminal domain-like 33
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 31
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 31
GAF domain-like PYP-like sensor domain (PAS domain) 32
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 32
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 31
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 33
FabD/lysophospholipase-like ACP-like 33
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 31
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 33
Nucleotidyltransferase ACT-like 32
Thiolase-like CoA-dependent acyltransferases 33
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Translation proteins ThrRS/AlaRS common domain 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Acetyl-CoA synthetase-like alpha/beta-Hydrolases 22
P-loop containing nucleoside triphosphate hydrolases MOP-like 21
Ankyrin repeat Pseudo ankyrin repeat-like 22
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 21
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 22
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 22
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Homeodomain-like Homeodomain-like 22
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 21
HD-domain/PDEase-like TGS-like 21
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 22
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
Cytochrome c Cytochrome c 22
Origin of replication-binding domain, RBD-like P-loop containing nucleoside triphosphate hydrolases 22
PUA domain-like Ribosomal protein S5 domain 2-like 21
Nucleotide-diphospho-sugar transferases RmlC-like cupins 22
Nucleotidyltransferase TGS-like 21
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 21
TPR-like S-adenosyl-L-methionine-dependent methyltransferases 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
HCP-like HCP-like 22
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 22
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
P-loop containing nucleoside triphosphate hydrolases Glucocorticoid receptor-like (DNA-binding domain) 22
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
ParB/Sulfiredoxin KorB DNA-binding domain-like 22
TGS-like ACT-like 21
Resolvase-like Homeodomain-like 21
ClpP/crotonase ClpP/crotonase 21
Thiolase-like alpha/beta-Hydrolases 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 22
Lysozyme-like beta-lactamase/transpeptidase-like 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Sensory domain-like Nucleotide cyclase 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
Phosphohistidine domain Glutathione synthetase ATP-binding domain-like 22
CoA-dependent acyltransferases NAD(P)-binding Rossmann-fold domains 22
2Fe-2S ferredoxin-like alpha-helical ferredoxin 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
HD-domain/PDEase-like Nucleotidyltransferase 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Acetyl-CoA synthetase-like Glycerol-3-phosphate (1)-acyltransferase 22
Translation proteins Ribosomal protein S5 domain 2-like 21
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
CheY-like EAL domain-like 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
PDZ domain-like PDZ domain-like 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 22
Cupredoxins Cupredoxins 22
ACP-like alpha/beta-Hydrolases 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
FabD/lysophospholipase-like Acetyl-CoA synthetase-like 22
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 22
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 22
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
NAD(P)-binding Rossmann-fold domains alpha/beta-Hydrolases 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
HlyD-like secretion proteins HlyD-like secretion proteins 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Acetyl-CoA synthetase-like NAD(P)-binding Rossmann-fold domains 22
HD-domain/PDEase-like ACT-like 21
PheT/TilS domain Class II aaRS and biotin synthetases 11
Translation proteins PRC-barrel domain 11
YajQ-like YajQ-like 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
ACT-like PLP-binding barrel 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, peptide-binding domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
ClpP/crotonase NfeD domain-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
cAMP-binding domain-like FabD/lysophospholipase-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
ISP domain Bet v1-like 11
PUA domain-like alpha/beta knot 11
Carbamate kinase-like PUA domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
GAF domain-like GAF domain-like 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
PreATP-grasp domain Single hybrid motif 11
Rhodanese/Cell cycle control phosphatase Glutathione synthetase ATP-binding domain-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
ACT-like Alanine racemase C-terminal domain-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
FabD/lysophospholipase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase Acetyl-CoA synthetase-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase FMN-dependent nitroreductase-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Ribokinase-like Thiamin phosphate synthase 11
Lysozyme-like LysM domain 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase GroES-like 11
Nucleotidylyl transferase tRNA-binding arm 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
Acetyl-CoA synthetase-like FMN-dependent nitroreductase-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Pentapeptide repeat-like Pentapeptide repeat-like 11
ACP-like FMN-dependent nitroreductase-like 11
Thiolase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Phospholipase D/nuclease Phospholipase D/nuclease 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III TK C-terminal domain-like 11
Carbamate kinase-like Alanine racemase C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Invasin/intimin cell-adhesion fragments Invasin/intimin cell-adhesion fragments 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
DNA clamp DNA clamp 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
CoA-dependent acyltransferases alpha/beta-Hydrolases 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
GroES-like GroES-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
CheY-like TPR-like 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
TGS-like Class II aaRS and biotin synthetases 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
DNA-glycosylase Nudix 11
Nucleotidyltransferase substrate binding subunit/domain Poly A polymerase C-terminal region-like 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III Thiamin diphosphate-binding fold (THDP-binding) 11
(Phosphotyrosine protein) phosphatases II HAD-like 11
Zinc beta-ribbon Zinc beta-ribbon 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
HAD-like HAD-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
FAD/NAD(P)-binding domain Alanine racemase C-terminal domain-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
DeoB insert domain-like Alkaline phosphatase-like 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
SGNH hydrolase Nucleotide-diphospho-sugar transferases 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
cAMP-binding domain-like "Winged helix" DNA-binding domain 11
Tex N-terminal region-like Ribonuclease H-like 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
FAD/NAD(P)-binding domain PLP-binding barrel 11
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, catalytic domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
RuvA domain 2-like RuvA domain 2-like 11
Hsp33 domain HSP33 redox switch-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Carbamate kinase-like PLP-binding barrel 11
PIN domain-like DNA/RNA polymerases 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Protease propeptides/inhibitors Subtilisin-like 11
CheY-like P-loop containing nucleoside triphosphate hydrolases 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Translation proteins Translation proteins 11
cAMP-binding domain-like cAMP-binding domain-like 11
NAD-binding domain of HMG-CoA reductase Substrate-binding domain of HMG-CoA reductase 11
Nucleotidyltransferase PAP/OAS1 substrate-binding domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
P-loop containing nucleoside triphosphate hydrolases Adenine nucleotide alpha hydrolases-like 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 11
RNase III domain-like dsRNA-binding domain-like 11
MetI-like MetI-like 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
FabD/lysophospholipase-like CoA-dependent acyltransferases 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Nucleic acid-binding proteins BRCT domain 11
NTF2-like Sec-C motif 11
Ribonuclease H-like RuvA domain 2-like 11
Pseudouridine synthase PUA domain-like 11
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 11
Immunoglobulin Immunoglobulin 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Carbamate kinase-like ACT-like 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 11
FabD/lysophospholipase-like alpha/beta-Hydrolases 11
PreATP-grasp domain PreATP-grasp domain 11
Periplasmic binding protein-like II GlnB-like 11
P-loop containing nucleoside triphosphate hydrolases Tropomyosin 11
Thiolase-like FMN-dependent nitroreductase-like 11
YjeF N-terminal domain-like Ribokinase-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Immunoglobulin Fibronectin type III 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Adenine nucleotide alpha hydrolases-like Nucleotidylyl transferase 11
Nudix Nudix 11
ADC synthase Class I glutamine amidotransferase-like 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Putative DNA-binding domain Translation proteins 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
GAF domain-like Phosphohistidine domain 11
ACT-like Formyltransferase 11
Bacterial fluorinating enzyme, N-terminal domain Bacterial fluorinating enzyme, C-terminal domain 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
YbjQ-like YbjQ-like 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
HisI-like all-alpha NTP pyrophosphatases 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
DNA methylase specificity domain DNA methylase specificity domain 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
S-adenosyl-L-methionine-dependent methyltransferases GroES-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Formyltransferase FMT C-terminal domain-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
FabD/lysophospholipase-like FMN-dependent nitroreductase-like 11
Dimeric alpha+beta barrel Dimeric alpha+beta barrel 11
C-type lectin-like S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
CarD-like TRCF domain-like 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Trigger factor ribosome-binding domain FKBP-like 11
S-adenosyl-L-methionine-dependent methyltransferases ACP-like 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
FAD-linked oxidoreductase ALDH-like 11
RNI-like P-loop containing nucleoside triphosphate hydrolases 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Bacterial muramidases Lysozyme-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Protein kinase-like (PK-like) LanC-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase CoA-dependent acyltransferases 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Cupredoxins Cytochrome c 11
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 11
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
PIN domain-like Ribonuclease H-like 11
LysM domain LysM domain 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Mss4-like Peptide methionine sulfoxide reductase 11
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 11
Tex N-terminal region-like RuvA domain 2-like 11
"Winged helix" DNA-binding domain C-terminal domain of arginine repressor 11
Acylphosphatase/BLUF domain-like PYP-like sensor domain (PAS domain) 11
PDZ domain-like ClpP/crotonase 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Thiolase-like GroES-like 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Ribosomal protein L6 Ribosomal protein L6 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
FMN-binding split barrel UbiD C-terminal domain-like 11
CoA-dependent acyltransferases FMN-dependent nitroreductase-like 11
Acylphosphatase/BLUF domain-like Nucleotide cyclase 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 11
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
ACT-like ACT-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Nudix Pseudo ankyrin repeat-like 11
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 11
Acetyl-CoA synthetase-like Acetyl-CoA synthetase-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Nucleotidyltransferase Nucleotidyltransferase 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
DNA primase core DNA primase DnaG, C-terminal domain 11
Ribonuclease H-like GIY-YIG endonuclease 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Ribokinase-like RmlC-like cupins 11
DPP6 N-terminal domain-like alpha/beta-Hydrolases 11
ACP-like Bacterial luciferase-like 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
PPK N-terminal domain-like PHP14-like 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
Thioesterase/thiol ester dehydrase-isomerase Isocitrate/Isopropylmalate dehydrogenase-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
FAD/NAD(P)-binding domain NAD(P)-binding Rossmann-fold domains 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Zinc beta-ribbon DNA primase core 11
Immunoglobulin Oligoxyloglucan reducing end-specific cellobiohydrolase 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Rhodanese/Cell cycle control phosphatase Phosphohistidine domain 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
L30e-like alpha/beta knot 11
Zn-dependent exopeptidases LysM domain 11
PHP domain-like Nucleic acid-binding proteins 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Clavaminate synthase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Class II aaRS and biotin synthetases Translation proteins 11
TerB-like Chaperone J-domain 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
PP2C-like PP2C-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
HAMP domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Sporulation related repeat OMPA-like 11
Putative DNA-binding domain Tetrahydrobiopterin biosynthesis enzymes-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
lambda repressor-like DNA-binding domains RmlC-like cupins 11
Nucleotide cyclase TPR-like 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
vWA-like Quinoprotein alcohol dehydrogenase-like 11
RmlC-like cupins Homeodomain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
P-loop containing nucleoside triphosphate hydrolases Rad50 coiled-coil Zn hook 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
F-box domain Protein kinase-like (PK-like) 11
CheY-like Methylesterase CheB, C-terminal domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
CheY-like Homeodomain-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
PheT/TilS domain Putative DNA-binding domain 11
Tropomyosin Duplicated hybrid motif 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Barwin-like endoglucanases Sporulation related repeat 11
Nudix Ankyrin repeat 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Sec7 domain RalF, C-terminal domain 11
Fibronectin type III Oligoxyloglucan reducing end-specific cellobiohydrolase 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Ribonuclease H-like P-loop containing nucleoside triphosphate hydrolases 11
Ribonuclease H-like DNA/RNA polymerases 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
GroEL-intermediate domain like GroEL apical domain-like 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 11
Macro domain-like Zn-dependent exopeptidases 11
GroES-like ACP-like 11
Sialidases Sialidases 11
PRTase-like PRTase-like 11
Adenine nucleotide alpha hydrolases-like GAF domain-like 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Ribosome binding protein Y (YfiA homologue) Nucleic acid-binding proteins 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Rudiment single hybrid motif Single hybrid motif 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases C-terminal effector domain of the bipartite response regulators 11
TGS-like ThrRS/AlaRS common domain 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
FKBP-like FKBP-like 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
FabD/lysophospholipase-like GroES-like 11
Poly A polymerase C-terminal region-like ACT-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Histidine-containing phosphotransfer domain, HPT domain Nucleotide cyclase 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
HAD-like SGNH hydrolase 11
PreATP-grasp domain Methylglyoxal synthase-like 11
TGS-like Class II aaRS ABD-related 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
PHP14-like Phospholipase D/nuclease 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Nucleic acid-binding proteins GAD domain-like 11
Single hybrid motif Single hybrid motif 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
YrdC/RibB RibA-like 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
P-loop containing nucleoside triphosphate hydrolases GAF domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
HAD-like Ribosomal protein S5 domain 2-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
RuvA domain 2-like BRCT domain 11
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase S-adenosyl-L-methionine-dependent methyltransferases 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Nucleic acid-binding proteins PheT/TilS domain 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11

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