SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Azoarcus sp. KH32C

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


Add or remove domain pairs

The links below permit the addition or removal of specific sets of domain combination pairs.


Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Add or remove genomes

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Add or remove genomes:
Include genomes:
Exclude genomes:


Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

809 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 7333
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 521
Nucleotide cyclase EAL domain-like 4425
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 4025
PYP-like sensor domain (PAS domain) Nucleotide cyclase 3723
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 3422
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 3315
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 3318
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 323
CheY-like C-terminal effector domain of the bipartite response regulators 312
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 2810
CheY-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 2824
Thiolase-like Thiolase-like 281
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 275
PYP-like sensor domain (PAS domain) EAL domain-like 2416
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 247
CheY-like Homodimeric domain of signal transducing histidine kinase 2319
CheY-like PYP-like sensor domain (PAS domain) 2217
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 228
CheY-like P-loop containing nucleoside triphosphate hydrolases 185
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 175
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 173
CheY-like Homeodomain-like 163
CheY-like Nucleotide cyclase 1513
GAF domain-like Nucleotide cyclase 1511
CheY-like CheY-like 1514
Actin-like ATPase domain Actin-like ATPase domain 155
GroES-like NAD(P)-binding Rossmann-fold domains 152
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 152
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 149
Thioredoxin-like GST C-terminal domain-like 121
GAF domain-like EAL domain-like 128
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 113
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 116
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 118
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 115
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 111
HAMP domain-like Nucleotide cyclase 115
EAL domain-like CheY-like 1110
Homeodomain-like Homeodomain-like 115
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 116
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 113
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 101
P-loop containing nucleoside triphosphate hydrolases Translation proteins 106
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 103
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 104
HAMP domain-like PYP-like sensor domain (PAS domain) 95
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 95
beta-Roll beta-Roll 98
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 95
P-loop containing nucleoside triphosphate hydrolases MOP-like 92
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 94
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 95
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 96
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 95
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 91
Cytochrome c Cytochrome c 96
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 95
"Winged helix" DNA-binding domain PLP-dependent transferases 91
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 96
Histidine-containing phosphotransfer domain, HPT domain CheW-like 83
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 88
CheY-like Histidine-containing phosphotransfer domain, HPT domain 88
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 81
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 81
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 83
CheY-like HD-domain/PDEase-like 83
PreATP-grasp domain Rudiment single hybrid motif 84
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 85
cAMP-binding domain-like "Winged helix" DNA-binding domain 82
PYP-like sensor domain (PAS domain) GAF domain-like 88
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 82
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 83
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 84
P-loop containing nucleoside triphosphate hydrolases C-terminal effector domain of the bipartite response regulators 73
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 75
GAF domain-like CheY-like 77
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 73
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 64
Folate-binding domain Aminomethyltransferase beta-barrel domain 63
Calcium ATPase, transduction domain A HAD-like 65
Triger factor/SurA peptide-binding domain-like FKBP-like 64
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 65
HAD-like Calcium ATPase, transmembrane domain M 65
"Winged helix" DNA-binding domain GAF domain-like 61
GAF domain-like GAF domain-like 64
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 63
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 63
Class I glutamine amidotransferase-like Homeodomain-like 61
Homodimeric domain of signal transducing histidine kinase CheW-like 61
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 65
PurM N-terminal domain-like PurM C-terminal domain-like 62
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
Trypsin-like serine proteases PDZ domain-like 64
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 63
CheY-like Methylesterase CheB, C-terminal domain 61
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 54
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 52
ClpP/crotonase ClpP/crotonase 52
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 53
HAMP domain-like EAL domain-like 52
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 54
ISP domain Bet v1-like 52
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 52
PDZ domain-like PDZ domain-like 54
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 52
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 52
Alpha-L RNA-binding motif Pseudouridine synthase 52
PLP-binding barrel Alanine racemase C-terminal domain-like 52
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 52
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 54
Translation proteins EF-G C-terminal domain-like 53
Single hybrid motif CoA-dependent acyltransferases 52
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 53
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 52
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
TPR-like TPR-like 44
Rudiment single hybrid motif Single hybrid motif 42
ACT-like ACT-like 43
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 43
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 43
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 43
EF-G C-terminal domain-like EF-G C-terminal domain-like 42
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
FMN-binding split barrel UbiD C-terminal domain-like 42
TPR-like C-terminal effector domain of the bipartite response regulators 43
Phospholipase D/nuclease Phospholipase D/nuclease 43
2Fe-2S ferredoxin-like alpha-helical ferredoxin 42
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 43
GAF domain-like Homodimeric domain of signal transducing histidine kinase 44
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 42
CheW-like CheY-like 43
GAF domain-like Homeodomain-like 43
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 42
PreATP-grasp domain Single hybrid motif 42
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 42
Chaperone J-domain HSP40/DnaJ peptide-binding domain 43
HD-domain/PDEase-like GAF domain-like 44
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 44
HAMP domain-like CheY-like 44
Porins Porins 42
Nqo1 middle domain-like Nqo1C-terminal domain-like 43
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 43
Glutathione synthetase ATP-binding domain-like Single hybrid motif 42
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 33
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 33
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
HD-domain/PDEase-like ACT-like 32
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 31
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 31
4Fe-4S ferredoxins Thiamin diphosphate-binding fold (THDP-binding) 33
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 32
Aldolase post-HMGL domain-like 32
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 32
Sensory domain-like Nucleotide cyclase 32
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 32
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Cupredoxins Cytochrome c 32
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
Phage tail proteins Phage tail proteins 33
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 31
Thioredoxin-like Nqo1 FMN-binding domain-like 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 32
ACT-like Formyltransferase 31
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 32
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 31
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 32
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 31
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 33
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 32
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
(Trans)glycosidases Glycosyl hydrolase domain 32
Nucleotidyltransferase HD-domain/PDEase-like 32
Multiheme cytochromes Multiheme cytochromes 33
Enolase N-terminal domain-like Enolase C-terminal domain-like 31
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 31
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 31
CBS-domain pair FAD-binding/transporter-associated domain-like 31
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 33
PK beta-barrel domain-like PK C-terminal domain-like 31
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 32
P-loop containing nucleoside triphosphate hydrolases TPR-like 32
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 32
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 32
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 33
Phage tail proteins gp5 N-terminal domain-like 33
MetI-like MetI-like 31
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 32
Nucleotide-binding domain Nucleotide-binding domain 33
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 32
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
alpha-helical ferredoxin 4Fe-4S ferredoxins 33
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 31
Nucleotidyltransferase ACT-like 32
HlyD-like secretion proteins HlyD-like secretion proteins 32
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 32
Succinyl-CoA synthetase domains Glutathione synthetase ATP-binding domain-like 32
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Thioredoxin-like Nqo1C-terminal domain-like 32
Nucleic acid-binding proteins RuvA domain 2-like 33
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
alpha-helical ferredoxin Nucleotide-binding domain 33
Thioredoxin-like Nqo1 middle domain-like 32
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 31
Fic-like "Winged helix" DNA-binding domain 21
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
PLP-dependent transferases PLP-dependent transferases 21
Homeodomain-like SIS domain 22
TGS-like ACT-like 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
Nucleotide cyclase SMAD/FHA domain 21
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 21
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 22
Aldehyde ferredoxin oxidoreductase, N-terminal domain Aldehyde ferredoxin oxidoreductase, C-terminal domains 22
PYP-like sensor domain (PAS domain) Homeodomain-like 22
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 21
Ribonuclease H-like GIY-YIG endonuclease 21
MoeA N-terminal region -like MoeA C-terminal domain-like 21
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
Formyltransferase FMT C-terminal domain-like 22
Nucleotide-diphospho-sugar transferases RmlC-like cupins 21
Aldolase Single hybrid motif 21
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 21
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 21
Nqo1 FMN-binding domain-like alpha-helical ferredoxin 22
PreATP-grasp domain Aldolase 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
SMAD/FHA domain SMAD/FHA domain 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 22
Radical SAM enzymes Nitrogenase accessory factor-like 21
"Winged helix" DNA-binding domain Chorismate lyase-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 21
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 21
GroEL-intermediate domain like GroEL apical domain-like 21
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 21
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 22
Lysozyme-like beta-lactamase/transpeptidase-like 22
4Fe-4S ferredoxins 4Fe-4S ferredoxins 22
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 21
lambda repressor-like DNA-binding domains P-loop containing nucleoside triphosphate hydrolases 21
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Nucleotide-diphospho-sugar transferases UDP-Glycosyltransferase/glycogen phosphorylase 22
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 21
L30e-like alpha/beta knot 21
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
RmlC-like cupins Homeodomain-like 22
Ligand-binding domain in the NO signalling and Golgi transport P-loop containing nucleoside triphosphate hydrolases 21
Nucleotide-binding domain 4Fe-4S ferredoxins 22
Nucleotidyltransferase TGS-like 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
PP2C-like Protein kinase-like (PK-like) 21
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 22
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 21
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 21
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 21
(Trans)glycosidases Nucleotide-diphospho-sugar transferases 21
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 21
Translation proteins Ribosomal protein S5 domain 2-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 22
Cupredoxins Cupredoxins 22
GroEL equatorial domain-like GroEL apical domain-like 21
Glutathione synthetase ATP-binding domain-like Acyl-CoA N-acyltransferases (Nat) 21
Rudiment single hybrid motif post-HMGL domain-like 21
HD-domain/PDEase-like TGS-like 21
GroEL equatorial domain-like GroEL-intermediate domain like 21
Methylesterase CheB, C-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 22
Ligand-binding domain in the NO signalling and Golgi transport Homeodomain-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
LeuD/IlvD-like Aconitase iron-sulfur domain 22
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
Acetyl-CoA synthetase-like Glycerol-3-phosphate (1)-acyltransferase 22
HAMP domain-like GAF domain-like 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 22
PRTase-like PRTase-like 21
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 21
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 21
FAD/NAD(P)-binding domain Folate-binding domain 22
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 21
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 21
Methylesterase CheB, C-terminal domain PYP-like sensor domain (PAS domain) 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 21
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 21
4Fe-4S ferredoxins ADC-like 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 21
Galactose-binding domain-like Galactose-binding domain-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
2Fe-2S ferredoxin-like ADC-like 21
Methylesterase CheB, C-terminal domain Chemotaxis receptor methyltransferase CheR, N-terminal domain 22
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 21
Aspartate/glutamate racemase Aspartate/glutamate racemase 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
ParB/Sulfiredoxin KorB DNA-binding domain-like 21
Chemotaxis receptor methyltransferase CheR, N-terminal domain PYP-like sensor domain (PAS domain) 22
Cytochrome c C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase 22
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 21
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
Glutathione synthetase ATP-binding domain-like Aldolase 21
Rudiment single hybrid motif Aldolase 21
PreATP-grasp domain post-HMGL domain-like 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
S-adenosyl-L-methionine-dependent methyltransferases PYP-like sensor domain (PAS domain) 22
HMA, heavy metal-associated domain HAD-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Cobalamin (vitamin B12)-binding domain Radical SAM enzymes 22
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 21
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
post-HMGL domain-like Single hybrid motif 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
Glutathione synthetase ATP-binding domain-like post-HMGL domain-like 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 21
Galactose mutarotase-like Six-hairpin glycosidases 22
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 22
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 21
PUA domain-like Ribosomal protein S5 domain 2-like 21
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
RuvA domain 2-like BRCT domain 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
DNA polymerase beta, N-terminal domain-like PHP domain-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
FabD/lysophospholipase-like ACP-like 11
Macro domain-like Zn-dependent exopeptidases 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
PHP domain-like P-loop containing nucleoside triphosphate hydrolases 11
Thiolase-like GroES-like 11
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Radical SAM enzymes TPR-like 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
Sec63 N-terminal domain-like Nucleotidyltransferase 11
FAD-linked reductases, C-terminal domain Aminomethyltransferase beta-barrel domain 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Putative DNA-binding domain CheY-like 11
Trigger factor ribosome-binding domain FKBP-like 11
PP2C-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
MoaD/ThiS Rhodanese/Cell cycle control phosphatase 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
cAMP-binding domain-like PYP-like sensor domain (PAS domain) 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
TGS-like Class II aaRS and biotin synthetases 11
gp5 N-terminal domain-like Phage fibre proteins 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
2Fe-2S ferredoxin-like Nucleotide-binding domain 11
Carbamate kinase-like ACT-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
TGS-like ThrRS/AlaRS common domain 11
Phage tail proteins Phage fibre proteins 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Pseudouridine synthase PUA domain-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
NAD(P)-binding Rossmann-fold domains Citrate synthase 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
FKBP-like FKBP-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase GroES-like 11
Methyl-accepting chemotaxis protein (MCP) signaling domain Hemerythrin-like 11
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 11
Calcium-dependent phosphotriesterase Calcium-dependent phosphotriesterase 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 11
FliG FliG 11
Quinoprotein alcohol dehydrogenase-like WD40 repeat-like 11
4Fe-4S ferredoxins Radical SAM enzymes 11
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Methyl-accepting chemotaxis protein (MCP) signaling domain PilZ domain-like 11
HD-domain/PDEase-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
cAMP-binding domain-like Nucleotidyltransferase 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
Thioesterase/thiol ester dehydrase-isomerase Isocitrate/Isopropylmalate dehydrogenase-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Nucleic acid-binding proteins PheT/TilS domain 11
FAD/NAD(P)-binding domain ISP domain 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Ligand-binding domain in the NO signalling and Golgi transport ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
FAD-linked reductases, C-terminal domain Folate-binding domain 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Putative DNA-binding domain Translation proteins 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
cAMP-binding domain-like cAMP-binding domain-like 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
PIN domain-like DNA/RNA polymerases 11
Nudix Thiamin phosphate synthase 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Nucleic acid-binding proteins BRCT domain 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
RuvA domain 2-like MCP/YpsA-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
Dimeric alpha+beta barrel Dimeric alpha+beta barrel 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
PH0987 N-terminal domain-like Cyclophilin-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
YajQ-like YajQ-like 11
Nucleotide cyclase Hemerythrin-like 11
Thiolase-like NAD(P)-binding Rossmann-fold domains 11
PUA domain-like alpha/beta knot 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 11
Galactose mutarotase-like Fibronectin type III 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
Translation proteins ThrRS/AlaRS common domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
RNase III domain-like dsRNA-binding domain-like 11
Starch-binding domain-like Calcium-dependent phosphotriesterase 11
P-loop containing nucleoside triphosphate hydrolases Quinoprotein alcohol dehydrogenase-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Nitrous oxide reductase, N-terminal domain Cupredoxins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
CBS-domain pair Nucleotidyltransferase 11
PurS-like FGAM synthase PurL, linker domain 11
NAD(P)-binding Rossmann-fold domains ACP-like 11
Nucleotide-diphospho-sugar transferases Alkaline phosphatase-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
SMAD/FHA domain HD-domain/PDEase-like 11
ARM repeat ARM repeat 11
P-loop containing nucleoside triphosphate hydrolases Cobalamin (vitamin B12)-dependent enzymes 11
P-loop containing nucleoside triphosphate hydrolases WD40 repeat-like 11
Tropomyosin Duplicated hybrid motif 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
Thiolase-like ACP-like 11
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Methionine synthase domain Methionine synthase activation domain-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
PPK N-terminal domain-like PHP14-like 11
RuBisCO, large subunit, small (N-terminal) domain RuBisCo, C-terminal domain 11
RuvA domain 2-like RuvA domain 2-like 11
FMT C-terminal domain-like ClpP/crotonase 11
PIN domain-like Ribonuclease H-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
PurS-like PurM N-terminal domain-like 11
YgfB-like Sec-C motif 11
Sensory domain-like HAMP domain-like 11
Cobalamin (vitamin B12)-binding domain P-loop containing nucleoside triphosphate hydrolases 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
PheT/TilS domain Putative DNA-binding domain 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Quinohemoprotein amine dehydrogenase A chain, domain 3 E set domains 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Respiratory nitrate reductase 1 gamma chain alpha-helical ferredoxin 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Cytochrome c E set domains 11
CheY-like PP2C-like 11
S-adenosyl-L-methionine-dependent methyltransferases Tropomyosin 11
PHP14-like Phospholipase D/nuclease 11
Zinc beta-ribbon DNA primase core 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
CBS-domain pair MgtE membrane domain-like 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Single hybrid motif alpha/beta-Hydrolases 11
FMN-dependent nitroreductase-like FMN-dependent nitroreductase-like 11
Nucleotidyltransferase PHP domain-like 11
Ribonuclease H-like RuvA domain 2-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
NAD(P)-binding Rossmann-fold domains RmlC-like cupins 11
S-adenosyl-L-methionine-dependent methyltransferases TPR-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
Globin-like HAMP domain-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
S-adenosyl-L-methionine-dependent methyltransferases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
GroES-like ACP-like 11
Protein kinase-like (PK-like) cAMP-binding domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Single hybrid motif FAD/NAD(P)-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Thiolase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Hsp33 domain HSP33 redox switch-like 11
beta-Roll CalX-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
S-adenosyl-L-methionine-dependent methyltransferases ACP-like 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Chorismate mutase II ACT-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Regulatory protein AraC Homeodomain-like 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Dihydropteroate synthetase-like Methionine synthase domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Metalloproteases ("zincins"), catalytic domain PDZ domain-like 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
HprK N-terminal domain-like PEP carboxykinase-like 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 11
Single hybrid motif Single hybrid motif 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
Ribonuclease H-like DNA/RNA polymerases 11
C-type lectin-like beta-Roll 11
Putative DNA-binding domain Cobalamin (vitamin B12)-binding domain 11
(Phosphotyrosine protein) phosphatases II PLP-dependent transferases 11
CheY-like EspE N-terminal domain-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Oxidoreductase molybdopterin-binding domain E set domains 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 11
Ligand-binding domain in the NO signalling and Golgi transport Homodimeric domain of signal transducing histidine kinase 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Ligand-binding domain in the NO signalling and Golgi transport PYP-like sensor domain (PAS domain) 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Globin-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
FAD-linked oxidoreductase ALDH-like 11
Putative DNA-binding domain TPR-like 11
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 11
Voltage-gated potassium channels TrkA C-terminal domain-like 11
D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain Cobalamin (vitamin B12)-binding domain 11
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Globin-like Riboflavin synthase domain-like 11
PurS-like Class I glutamine amidotransferase-like 11
Aldehyde ferredoxin oxidoreductase, C-terminal domains MoaD/ThiS 11
Ribosome binding protein Y (YfiA homologue) Nucleic acid-binding proteins 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
EPT/RTPC-like P-loop containing nucleoside triphosphate hydrolases 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 11
Class II aaRS and biotin synthetases GAD domain-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Actin-like ATPase domain SIS domain 11
Cupredoxins Hypothetical protein PA1324 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Nqo5-like HydB/Nqo4-like 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
lambda repressor-like DNA-binding domains DNA breaking-rejoining enzymes 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
S-adenosyl-L-methionine-dependent methyltransferases GroES-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
TPR-like NTF2-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
vWA-like Quinoprotein alcohol dehydrogenase-like 11
DNA-glycosylase Nudix 11
PreATP-grasp domain PreATP-grasp domain 11
cAMP-binding domain-like CBS-domain pair 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
SMAD/FHA domain GAF domain-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase S-adenosyl-L-methionine-dependent methyltransferases 11
Lysozyme-like PGBD-like 11
PYP-like sensor domain (PAS domain) Hemerythrin-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Aldolase RmlC-like cupins 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
cAMP-binding domain-like P-loop containing nucleoside triphosphate hydrolases 11
Cytochrome c Quinohemoprotein amine dehydrogenase A chain, domain 3 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
CheC-like Surface presentation of antigens (SPOA) 11
Methylesterase CheB, C-terminal domain Tropomyosin 11
(Trans)glycosidases (Trans)glycosidases 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Formylmethanofuran:tetrahydromethanopterin formyltransferase Formylmethanofuran:tetrahydromethanopterin formyltransferase 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Ferritin-like Calcium ATPase, transmembrane domain M 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
"Winged helix" DNA-binding domain PYP-like sensor domain (PAS domain) 11
EreA/ChaN-like PDZ domain-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Periplasmic binding protein-like II Lysozyme-like 11
Translation proteins Translation proteins 11
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
YjeF N-terminal domain-like Ribokinase-like 11
cAMP-binding domain-like ABC transporter transmembrane region 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
ClpP/crotonase NfeD domain-like 11
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 11
Class II aaRS and biotin synthetases Translation proteins 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Periplasmic binding protein-like II ACT-like 11
Aldehyde ferredoxin oxidoreductase, N-terminal domain MoaD/ThiS 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Sec63 N-terminal domain-like PHP domain-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
PilZ domain-like PilZ domain-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Six-hairpin glycosidases Fibronectin type III 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Nucleic acid-binding proteins GAD domain-like 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Arginase/deacetylase PLP-dependent transferases 11
Protein kinase-like (PK-like) Protein kinase-like (PK-like) 11
DNA polymerase beta, N-terminal domain-like Sec63 N-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
CarD-like TRCF domain-like 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
HAMP domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Tex N-terminal region-like Ribonuclease H-like 11
L,D-transpeptidase catalytic domain-like NTF2-like 11
Barwin-like endoglucanases Sporulation related repeat 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
E set domains E set domains 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Cobalamin (vitamin B12)-binding domain TPR-like 11
Tropomyosin PYP-like sensor domain (PAS domain) 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
GAF domain-like EspE N-terminal domain-like 11
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Formyltransferase ClpP/crotonase 11
MoaD/ThiS Activating enzymes of the ubiquitin-like proteins 11
YrdC/RibB RibA-like 11
MgtE N-terminal domain-like CBS-domain pair 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Actin-like ATPase domain Homeodomain-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
HD-domain/PDEase-like Nucleotide cyclase 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
alpha-helical ferredoxin alpha-helical ferredoxin 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
4Fe-4S ferredoxins Respiratory nitrate reductase 1 gamma chain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Nucleotidylyl transferase tRNA-binding arm 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
HCP-like Lysozyme-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
beta-lactamase/transpeptidase-like beta-lactamase/transpeptidase-like 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
FabD/lysophospholipase-like GroES-like 11
FMN-binding split barrel GAF domain-like 11
ACP-like Glycerol-3-phosphate (1)-acyltransferase 11
Thiolase-like Nucleic acid-binding proteins 11
Chorismate mutase II Periplasmic binding protein-like II 11
Lysozyme-like LysM domain 11
Tex N-terminal region-like RuvA domain 2-like 11
SGNH hydrolase Autotransporter 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Quinoprotein alcohol dehydrogenase-like Fibronectin type III 11
TGS-like Class II aaRS ABD-related 11
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 11
Bacterial muramidases Lysozyme-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
alpha/beta-Hydrolases RmlC-like cupins 11
lambda repressor-like DNA-binding domains RmlC-like cupins 11
FabD/lysophospholipase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Ribosomal protein L6 Ribosomal protein L6 11
4Fe-4S ferredoxins Riboflavin synthase domain-like 11
E set domains (Trans)glycosidases 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
DNA clamp DNA clamp 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Galactose mutarotase-like Galactose mutarotase-like 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
FAD-linked oxidases, C-terminal domain FAD-linked oxidases, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases PGBD-like 11
Rhodanese/Cell cycle control phosphatase Activating enzymes of the ubiquitin-like proteins 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
vWA-like TPR-like 11
Carbamate kinase-like PUA domain-like 11
4Fe-4S ferredoxins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
FMN-linked oxidoreductases Nucleotide-binding domain 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain Tropomyosin 11
Metalloproteases ("zincins"), catalytic domain beta-Roll 11
Nucleotidylyl transferase Riboflavin kinase-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Acyl-CoA N-acyltransferases (Nat) beta-carbonic anhydrase, cab 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Ferritin-like HAD-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
C-type lectin-like S-adenosyl-L-methionine-dependent methyltransferases 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Metalloproteases ("zincins"), catalytic domain CalX-like 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nudix Nudix 11
Translation proteins PRC-barrel domain 11
L,D-transpeptidase catalytic domain-like Acyl-CoA N-acyltransferases (Nat) 11
CheY-like TPR-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
DNA primase core DNA primase DnaG, C-terminal domain 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Succinyl-CoA synthetase domains Citrate synthase 11
RmlC-like cupins RmlC-like cupins 11
DNA methylase specificity domain DNA methylase specificity domain 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Metallo-hydrolase/oxidoreductase Rhodanese/Cell cycle control phosphatase 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Ferritin-like Calcium ATPase, transduction domain A 11
Hemerythrin-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
HAD-like PRTase-like 11
PDZ domain-like ClpP/crotonase 11
ACP-like Acetyl-CoA synthetase-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
PurS-like PurM C-terminal domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Ankyrin repeat NTF2-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Thiolase-like FabD/lysophospholipase-like 11

Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes · Domain combination pairs ]