SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Methylobacterium sp. 4-46

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

798 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 7545
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 591
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 4736
Homodimeric domain of signal transducing histidine kinase CheY-like 4532
CheY-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 4532
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 4317
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 3936
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 3830
PYP-like sensor domain (PAS domain) CheY-like 3023
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 263
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 241
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 246
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 234
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 237
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 225
CheY-like C-terminal effector domain of the bipartite response regulators 213
NAD(P)-binding Rossmann-fold domains GroES-like 205
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 192
cAMP-binding domain-like "Winged helix" DNA-binding domain 193
Thioredoxin-like GST C-terminal domain-like 191
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 186
Nucleotide cyclase EAL domain-like 176
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 176
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 165
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 165
GAF domain-like PYP-like sensor domain (PAS domain) 1615
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 165
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 165
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 165
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 154
Homeodomain-like Ribonuclease H-like 152
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1515
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 152
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 144
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 141
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 143
GAF domain-like Homodimeric domain of signal transducing histidine kinase 1313
P-loop containing nucleoside triphosphate hydrolases MOP-like 131
CheY-like CheY-like 1310
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 137
Thiolase-like Thiolase-like 123
GAF domain-like CheY-like 1212
PYP-like sensor domain (PAS domain) Nucleotide cyclase 126
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 114
(Trans)glycosidases Glycosyl hydrolase domain 105
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 103
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 105
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 103
PYP-like sensor domain (PAS domain) EAL domain-like 104
Homeodomain-like Homeodomain-like 95
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 95
Actin-like ATPase domain Actin-like ATPase domain 93
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 94
P-loop containing nucleoside triphosphate hydrolases Translation proteins 97
Enolase N-terminal domain-like Enolase C-terminal domain-like 91
Lysozyme-like beta-lactamase/transpeptidase-like 84
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 85
CheY-like P-loop containing nucleoside triphosphate hydrolases 72
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 74
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 77
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 72
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 71
beta-Roll beta-Roll 76
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 74
TPR-like TPR-like 74
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 71
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 71
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 71
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 66
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 65
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
Calcium ATPase, transduction domain A HAD-like 66
CheY-like Histidine-containing phosphotransfer domain, HPT domain 66
lambda repressor-like DNA-binding domains RmlC-like cupins 61
Trypsin-like serine proteases PDZ domain-like 62
E set domains (Trans)glycosidases 63
HAD-like Calcium ATPase, transmembrane domain M 66
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 66
Nucleic acid-binding proteins Nucleic acid-binding proteins 65
"Winged helix" DNA-binding domain GAF domain-like 61
CheY-like Homeodomain-like 61
CheY-like Nucleotide cyclase 65
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 52
"Winged helix" DNA-binding domain Chorismate lyase-like 52
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 53
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 54
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 54
Single hybrid motif CoA-dependent acyltransferases 52
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 52
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 54
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 51
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 54
MoeA N-terminal region -like MoeA C-terminal domain-like 53
Nucleotide cyclase TPR-like 52
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 51
PreATP-grasp domain Rudiment single hybrid motif 52
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 51
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 54
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 53
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 54
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 52
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 54
E set domains Glycosyl hydrolase domain 52
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 53
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 54
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 51
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 52
TPR-like Caspase-like 44
Alpha-L RNA-binding motif Pseudouridine synthase 43
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 42
Resolvase-like Homeodomain-like 41
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 43
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 42
HAMP domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 42
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 43
PGBD-like L,D-transpeptidase catalytic domain-like 42
Cytochrome c Cytochrome c 42
HlyD-like secretion proteins HlyD-like secretion proteins 42
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 41
PurM N-terminal domain-like PurM C-terminal domain-like 42
GAF domain-like GAF domain-like 44
Translation proteins EF-G C-terminal domain-like 43
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 43
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 43
GAF domain-like Nucleotide cyclase 43
EF-G C-terminal domain-like EF-G C-terminal domain-like 43
Acetyl-CoA synthetase-like ACP-like 44
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 43
RmlC-like cupins Homeodomain-like 43
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 43
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 41
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 41
Triger factor/SurA peptide-binding domain-like FKBP-like 43
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 41
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 43
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 33
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 32
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 31
FabD/lysophospholipase-like ACP-like 33
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 31
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 33
PK beta-barrel domain-like PK C-terminal domain-like 31
Galactose mutarotase-like E set domains 31
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 31
Phase 1 flagellin Phase 1 flagellin 31
Thiolase-like FabD/lysophospholipase-like 33
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 33
GroEL equatorial domain-like GroEL apical domain-like 31
Nqo1 middle domain-like Nqo1C-terminal domain-like 33
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Formyltransferase FMT C-terminal domain-like 31
GroEL equatorial domain-like GroEL-intermediate domain like 31
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 31
(Trans)glycosidases (Trans)glycosidases 33
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 31
alpha/beta-Hydrolases alpha/beta-Hydrolases 31
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 31
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 33
NAD(P)-binding Rossmann-fold domains ACP-like 33
Lysozyme-like PGBD-like 31
Nucleic acid-binding proteins RuvA domain 2-like 33
Class I glutamine amidotransferase-like Homeodomain-like 31
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 33
CheY-like HD-domain/PDEase-like 31
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 33
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 33
MetI-like MetI-like 33
"Winged helix" DNA-binding domain PLP-dependent transferases 31
NAD(P)-binding Rossmann-fold domains ACT-like 33
Thiolase-like NAD(P)-binding Rossmann-fold domains 33
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 31
GroEL-intermediate domain like GroEL apical domain-like 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 31
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 33
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 33
Thiolase-like ACP-like 33
Regulatory protein AraC Homeodomain-like 31
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 33
CheY-like Methylesterase CheB, C-terminal domain 32
CBS-domain pair FAD-binding/transporter-associated domain-like 31
PLP-binding barrel Alanine racemase C-terminal domain-like 31
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 33
PDZ domain-like PDZ domain-like 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 33
Histidine-containing phosphotransfer domain, HPT domain CheW-like 33
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 33
ACT-like ACT-like 33
Phospholipase D/nuclease Phospholipase D/nuclease 33
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 33
ClpP/crotonase ClpP/crotonase 31
Methyl-accepting chemotaxis protein (MCP) signaling domain Methyl-accepting chemotaxis protein (MCP) signaling domain 33
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 22
PreATP-grasp domain Single hybrid motif 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 22
ISP domain Bet v1-like 21
RuvA domain 2-like P-loop containing nucleoside triphosphate hydrolases 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 21
HAMP domain-like Nucleotide cyclase 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
FabD/lysophospholipase-like GroES-like 22
Trimeric LpxA-like enzymes Trimeric LpxA-like enzymes 22
CO dehydrogenase ISP C-domain like CO dehydrogenase molybdoprotein N-domain-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 22
Single hybrid motif FAD/NAD(P)-binding domain 22
Cupredoxins Cytochrome c 22
Metallo-dependent phosphatases beta-Roll 22
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 22
CarD-like TRCF domain-like 22
Nucleotidyltransferase ACT-like 22
Thioredoxin-like Nqo1 FMN-binding domain-like 22
P-loop containing nucleoside triphosphate hydrolases MetI-like 22
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 22
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 22
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
Methyl-accepting chemotaxis protein (MCP) signaling domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 22
CO dehydrogenase ISP C-domain like Molybdenum cofactor-binding domain 21
PDZ domain-like ClpP/crotonase 22
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 21
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 21
Acetyl-CoA synthetase-like Glycerol-3-phosphate (1)-acyltransferase 22
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
Metalloproteases ("zincins"), catalytic domain Integrin alpha N-terminal domain 22
GroES-like ACP-like 22
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Oxidoreductase molybdopterin-binding domain E set domains 21
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 22
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 22
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 22
HMA, heavy metal-associated domain HAD-like 22
Homodimeric domain of signal transducing histidine kinase CheW-like 22
ParB/Sulfiredoxin KorB DNA-binding domain-like 21
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 21
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 22
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 21
Folate-binding domain Aminomethyltransferase beta-barrel domain 22
CheW-like CheY-like 22
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 22
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 21
C-terminal effector domain of the bipartite response regulators TPR-like 21
Cupredoxins Cupredoxins 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
2Fe-2S ferredoxin-like Molybdenum cofactor-binding domain 21
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 22
Thioredoxin-like Nqo1C-terminal domain-like 22
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 21
Aconitase iron-sulfur domain LeuD/IlvD-like 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
FabD/lysophospholipase-like FabD/lysophospholipase-like 22
Translation proteins Ribosomal protein S5 domain 2-like 21
Methyl-accepting chemotaxis protein (MCP) signaling domain Homodimeric domain of signal transducing histidine kinase 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
4Fe-4S ferredoxins ADC-like 22
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 21
Probable ACP-binding domain of malonyl-CoA ACP transacylase GroES-like 22
Glutathione synthetase ATP-binding domain-like Single hybrid motif 21
CheW-like CheW-like 22
Methyl-accepting chemotaxis protein (MCP) signaling domain PilZ domain-like 22
Thiolase-like GroES-like 22
Methyl-accepting chemotaxis protein (MCP) signaling domain CheY-like 22
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 21
HCP-like HCP-like 22
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Galactose oxidase, central domain E set domains 22
TPR-like S-adenosyl-L-methionine-dependent methyltransferases 22
Lysozyme-like Staphylococcal nuclease 21
Flavoproteins Riboflavin synthase domain-like 21
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 22
CheC-like Surface presentation of antigens (SPOA) 22
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 22
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 22
Acyl-CoA N-acyltransferases (Nat) Glutathione synthetase ATP-binding domain-like 22
Metalloproteases ("zincins"), catalytic domain beta-Roll 22
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 22
Thioredoxin-like Nqo1 middle domain-like 22
Nucleotide-diphospho-sugar transferases UDP-Glycosyltransferase/glycogen phosphorylase 22
ACP-like ACP-like 22
PGBD-like Trypsin-like serine proteases 22
GAF domain-like EAL domain-like 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Rudiment single hybrid motif Single hybrid motif 21
L30e-like alpha/beta knot 21
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 21
Globin-like Methyl-accepting chemotaxis protein (MCP) signaling domain 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 21
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 21
TrkA C-terminal domain-like TrkA C-terminal domain-like 21
Probable ACP-binding domain of malonyl-CoA ACP transacylase Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 22
Clc chloride channel CBS-domain pair 22
Metallo-hydrolase/oxidoreductase SCP-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
2Fe-2S ferredoxin-like CO dehydrogenase molybdoprotein N-domain-like 21
Globin-like Riboflavin synthase domain-like 21
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 22
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
P-loop containing nucleoside triphosphate hydrolases CarD-like 22
Methyl-accepting chemotaxis protein (MCP) signaling domain GAF domain-like 22
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 21
beta-lactamase/transpeptidase-like Staphylococcal nuclease 21
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 21
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 22
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 22
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 21
FliG FliG 21
Galactose mutarotase-like Six-hairpin glycosidases 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Carbamate kinase-like ACT-like 11
Nitrous oxide reductase, N-terminal domain Cupredoxins 11
alpha/beta-Hydrolases Acetyl-CoA synthetase-like 11
FabD/lysophospholipase-like S-adenosyl-L-methionine-dependent methyltransferases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Methylesterase CheB, C-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Cdc48 domain 2-like P-loop containing nucleoside triphosphate hydrolases 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Translation proteins PRC-barrel domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Nucleotide-binding domain Nucleotide-binding domain 11
Metallo-hydrolase/oxidoreductase CheY-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Caspase-like HCP-like 11
Folate-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
FAD-linked reductases, C-terminal domain Thioredoxin-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
HD-domain/PDEase-like TGS-like 11
FAD-linked reductases, C-terminal domain Folate-binding domain 11
RuvA domain 2-like BRCT domain 11
Methylesterase CheB, C-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Concanavalin A-like lectins/glucanases Concanavalin A-like lectins/glucanases 11
RNase III domain-like dsRNA-binding domain-like 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
beta-Barrel protease inhibitors beta-Barrel protease inhibitors 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
CO dehydrogenase ISP C-domain like Bet v1-like 11
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
OmpA-like OmpA-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
PPK N-terminal domain-like PHP14-like 11
Thioredoxin-like TPR-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
beta-Roll Hedgehog/intein (Hint) domain 11
Fumarate reductase respiratory complex transmembrane subunits Nucleotide cyclase 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Tropomyosin PYP-like sensor domain (PAS domain) 11
PYP-like sensor domain (PAS domain) lambda repressor-like DNA-binding domains 11
ACP-like Trimeric LpxA-like enzymes 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain beta-Roll 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain "Winged helix" DNA-binding domain 11
PreATP-grasp domain PreATP-grasp domain 11
Ribonuclease H-like RuvA domain 2-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
DNase I-like beta-Roll 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
P-loop containing nucleoside triphosphate hydrolases vWA-like 11
Ricin B-like lectins E set domains 11
WD40 repeat-like Cytochrome c 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Nucleic acid-binding proteins BRCT domain 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
"Winged helix" DNA-binding domain Bet v1-like 11
GAF domain-like Phosphohistidine domain 11
cAMP-binding domain-like FabD/lysophospholipase-like 11
YebC-like PFL-like glycyl radical enzymes 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
PIN domain-like DNA/RNA polymerases 11
Tricorn protease N-terminal domain ClpP/crotonase 11
UDP-Glycosyltransferase/glycogen phosphorylase Glycoside hydrolase/deacetylase 11
DPP6 N-terminal domain-like ClpP/crotonase 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
S-adenosyl-L-methionine-dependent methyltransferases Tropomyosin 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
Photosystem II reaction centre subunit H, transmembrane region PRC-barrel domain 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
GAF domain-like Homeodomain-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Glycoside hydrolase/deacetylase UraD-Like 11
OMPA-like OMPA-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Metalloproteases ("zincins"), catalytic domain Hedgehog/intein (Hint) domain 11
PHP domain-like AF1531-like 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Molybdenum cofactor-binding domain Bet v1-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors NTF2-like 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Methylesterase CheB, C-terminal domain Chemotaxis receptor methyltransferase CheR, N-terminal domain 11
3-carboxy-cis,cis-mucoante lactonizing enzyme beta-Roll 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
GAF domain-like C-terminal effector domain of the bipartite response regulators 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
HPr-like Phosphohistidine domain 11
NAD(P)-binding Rossmann-fold domains MurD-like peptide ligases, peptide-binding domain 11
PUA domain-like alpha/beta knot 11
HAMP domain-like EAL domain-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
RuvA domain 2-like RuvA domain 2-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Galactose oxidase, central domain Galactose oxidase, central domain 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
DPP6 N-terminal domain-like PDZ domain-like 11
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Translation proteins Translation proteins 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Ricin B-like lectins Ricin B-like lectins 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Nucleotidyltransferase Nucleotidyltransferase 11
"Winged helix" DNA-binding domain SCP-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Nucleotidylyl transferase tRNA-binding arm 11
FAD-linked oxidoreductase ALDH-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
HD-domain/PDEase-like Nucleotidyltransferase 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
PHP14-like Phospholipase D/nuclease 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
beta-lactamase/transpeptidase-like Sporulation related repeat 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Cobalamin (vitamin B12)-binding domain Radical SAM enzymes 11
Ferritin-like HAD-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase S-adenosyl-L-methionine-dependent methyltransferases 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
2Fe-2S ferredoxin-like Nucleotide cyclase 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Translation proteins Periplasmic binding protein-like II 11
FMN-binding split barrel Ferredoxin reductase-like, C-terminal NADP-linked domain 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
FMN-binding split barrel UbiD C-terminal domain-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Ribonuclease H-like HRDC-like 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
OMPA-like OMPT-like 11
Caspase-like C-type lectin-like 11
Nudix "Winged helix" DNA-binding domain 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Nucleotide cyclase SMAD/FHA domain 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
lambda repressor-like DNA-binding domains P-loop containing nucleoside triphosphate hydrolases 11
Tex N-terminal region-like Ribonuclease H-like 11
Periplasmic binding protein-like II ACT-like 11
E set domains Quinoprotein alcohol dehydrogenase-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
beta-Roll Integrin alpha N-terminal domain 11
Tricorn protease N-terminal domain PDZ domain-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Class II aaRS and biotin synthetases Translation proteins 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Ricin B-like lectins Galactose oxidase, central domain 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Metallo-hydrolase/oxidoreductase GAF domain-like 11
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
L domain-like Protein kinase-like (PK-like) 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Translation proteins ThrRS/AlaRS common domain 11
Single hybrid motif TK C-terminal domain-like 11
PilZ domain-like PilZ domain-like 11
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 11
YlxR-like L30e-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
CBS-domain pair MgtE membrane domain-like 11
Zn-dependent exopeptidases "Winged helix" DNA-binding domain 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
TPR-like HCP-like 11
Nucleotide cyclase P-loop containing nucleoside triphosphate hydrolases 11
DAK1/DegV-like DhaL-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases PYP-like sensor domain (PAS domain) 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
DNA clamp DNA clamp 11
Nucleic acid-binding proteins GAD domain-like 11
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 11
TGS-like ThrRS/AlaRS common domain 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
RuvA domain 2-like JAB1/MPN domain 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
DNA-glycosylase Nudix 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
UraD-Like Transthyretin (synonym: prealbumin) 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
Folate-binding domain TrmE connector domain 11
MoeA C-terminal domain-like Periplasmic binding protein-like II 11
Glycosyl hydrolase domain Protein kinase-like (PK-like) 11
2Fe-2S ferredoxin-like Bet v1-like 11
NAD(P)-binding Rossmann-fold domains MurD-like peptide ligases, catalytic domain 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
DinB/YfiT-like putative metalloenzymes C-type lectin-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Urease, gamma-subunit Urease, beta-subunit 11
Zinc beta-ribbon DNA primase core 11
PheT/TilS domain Putative DNA-binding domain 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
TGS-like Class II aaRS and biotin synthetases 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
Methylesterase CheB, C-terminal domain Tropomyosin 11
Radical SAM enzymes RuvA domain 2-like 11
DeoB insert domain-like Alkaline phosphatase-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
FAD/NAD(P)-binding domain Folate-binding domain 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Thioesterase/thiol ester dehydrase-isomerase Isocitrate/Isopropylmalate dehydrogenase-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Methylesterase CheB, C-terminal domain PYP-like sensor domain (PAS domain) 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 11
AF0104/ALDC/Ptd012-like AF0104/ALDC/Ptd012-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
TGS-like ACT-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
DNA breaking-rejoining enzymes DNA breaking-rejoining enzymes 11
Integrin alpha N-terminal domain Integrin alpha N-terminal domain 11
Methionine synthase domain Methionine synthase activation domain-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
ABC transporter transmembrane region ABC transporter transmembrane region 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain TPR-like 11
Translation proteins "Winged helix" DNA-binding domain 11
Thiolase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Serine metabolism enzymes domain ACT-like 11
PYP-like sensor domain (PAS domain) Homeodomain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Bacterial muramidases Lysozyme-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Poly A polymerase C-terminal region-like ACT-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Ferritin-like Calcium ATPase, transduction domain A 11
LysM domain Duplicated hybrid motif 11
TerB-like Chaperone J-domain 11
NE0471 N-terminal domain-like lambda repressor-like DNA-binding domains 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Tropomyosin ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain Tropomyosin 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Acetamidase/Formamidase-like Acetamidase/Formamidase-like 11
Tricorn protease N-terminal domain DPP6 N-terminal domain-like 11
PIN domain-like Ribonuclease H-like 11
TGS-like Class II aaRS ABD-related 11
3-carboxy-cis,cis-mucoante lactonizing enzyme DNase I-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Molybdenum cofactor biosynthesis proteins Periplasmic binding protein-like II 11
Class II aaRS and biotin synthetases GAD domain-like 11
Concanavalin A-like lectins/glucanases Metallo-dependent phosphatases 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain PYP-like sensor domain (PAS domain) 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
MFS general substrate transporter Acetyl-CoA synthetase-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Nucleotide cyclase TolB, N-terminal domain 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases Periplasmic binding protein-like II 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
PspA lactotransferrin-binding region OmpA-like 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Pectin lyase-like Autotransporter 11
Homocysteine S-methyltransferase Methionine synthase domain 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
PreATP-grasp domain Methylglyoxal synthase-like 11
FAD/NAD(P)-binding domain Thioredoxin-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Carbamate kinase-like PUA domain-like 11
Radical SAM enzymes Nitrogenase accessory factor-like 11
MoeA N-terminal region -like Periplasmic binding protein-like II 11
alpha/beta-Hydrolases ACP-like 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
DNA topoisomerase I domain DNA breaking-rejoining enzymes 11
Hsp33 domain HSP33 redox switch-like 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
GroES-like GroES-like 11
ADC-like P-loop containing nucleoside triphosphate hydrolases 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
dUTPase-like dUTPase-like 11
Creatinase/prolidase N-terminal domain Creatinase/prolidase N-terminal domain 11
GIY-YIG endonuclease RuvA domain 2-like 11
CO dehydrogenase molybdoprotein N-domain-like Bet v1-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Soluble quinoprotein glucose dehydrogenase Cytochrome c 11
ACP-like Glycerol-3-phosphate (1)-acyltransferase 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain Periplasmic binding protein-like II 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
YrdC/RibB RibA-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
alpha-helical ferredoxin SCP-like 11
Single hybrid motif Thiamin diphosphate-binding fold (THDP-binding) 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Nucleotidyltransferase TGS-like 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Concanavalin A-like lectins/glucanases beta-Roll 11
PRTase-like EreA/ChaN-like 11
HAMP domain-like GAF domain-like 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
MalF N-terminal region-like MetI-like 11
HAMP domain-like CheY-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Ferritin-like Calcium ATPase, transmembrane domain M 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
FMN-binding split barrel Riboflavin synthase domain-like 11
HPr-like Phosphoenolpyruvate/pyruvate domain 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
CoA-transferase family III (CaiB/BaiF) CoA-transferase family III (CaiB/BaiF) 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
SIS domain CBS-domain pair 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
PLP-dependent transferases PLP-dependent transferases 11
ADC-like Cdc48 domain 2-like 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Ribonuclease H-like DNA/RNA polymerases 11
2Fe-2S ferredoxin-like ADC-like 11
cAMP-binding domain-like CBS-domain pair 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
S-adenosyl-L-methionine-dependent methyltransferases GroES-like 11
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
TPR-like Terpenoid cyclases/Protein prenyltransferases 11
Fumarate reductase respiratory complex transmembrane subunits 2Fe-2S ferredoxin-like 11
Formylmethanofuran:tetrahydromethanopterin formyltransferase Formylmethanofuran:tetrahydromethanopterin formyltransferase 11
SufE/NifU Fe-S cluster assembly (FSCA) domain-like 11
Acid phosphatase/Vanadium-dependent haloperoxidase Autotransporter 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Macro domain-like Zn-dependent exopeptidases 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
alpha/beta-Hydrolases AhpD-like 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
MgtE N-terminal domain-like CBS-domain pair 11
Nucleotide-diphospho-sugar transferases S-adenosyl-L-methionine-dependent methyltransferases 11
HRDC-like HRDC-like 11
Actin-like ATPase domain HD-domain/PDEase-like 11
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Sigma2 domain of RNA polymerase sigma factors NTF2-like 11
FMN-binding split barrel 2Fe-2S ferredoxin-like 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Galactose oxidase, central domain Quinoprotein alcohol dehydrogenase-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Nucleotidyltransferase substrate binding subunit/domain Poly A polymerase C-terminal region-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Tetrahydrobiopterin biosynthesis enzymes-like Tetrahydrobiopterin biosynthesis enzymes-like 11
Acetyl-CoA synthetase-like Trimeric LpxA-like enzymes 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Calcium-dependent phosphotriesterase Autotransporter 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
Ribosomal protein L6 Ribosomal protein L6 11
Homodimeric domain of signal transducing histidine kinase Nucleotide cyclase 11
S-adenosyl-L-methionine-dependent methyltransferases ACP-like 11
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 11
Aldolase SIS domain 11
YjeF N-terminal domain-like Ribokinase-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors CheY-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
RuBisCO, large subunit, small (N-terminal) domain RuBisCo, C-terminal domain 11
HD-domain/PDEase-like ACT-like 11
Nucleic acid-binding proteins PheT/TilS domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
FAD-linked reductases, C-terminal domain Aminomethyltransferase beta-barrel domain 11
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 11
Transmembrane di-heme cytochromes CBD9-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 11
Trigger factor ribosome-binding domain FKBP-like 11
PH0987 N-terminal domain-like Cyclophilin-like 11
S-adenosyl-L-methionine-dependent methyltransferases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
Tex N-terminal region-like RuvA domain 2-like 11

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