SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Xylella fastidiosa M23

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

534 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2314
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 127
Actin-like ATPase domain Actin-like ATPase domain 93
P-loop containing nucleoside triphosphate hydrolases Translation proteins 86
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 74
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 63
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 63
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 64
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 55
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 54
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 54
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 42
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 43
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
Homodimeric domain of signal transducing histidine kinase CheY-like 44
Translation proteins EF-G C-terminal domain-like 43
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 43
beta-Roll beta-Roll 44
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 43
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 43
Nucleic acid-binding proteins Nucleic acid-binding proteins 43
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 43
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 43
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 43
CheY-like C-terminal effector domain of the bipartite response regulators 41
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 32
Alpha-L RNA-binding motif Pseudouridine synthase 32
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 31
CheY-like Homeodomain-like 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 32
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 33
Nucleic acid-binding proteins Translation proteins SH3-like domain 32
DPP6 N-terminal domain-like alpha/beta-Hydrolases 32
FKBP-like Triger factor/SurA peptide-binding domain-like 33
Adhesin YadA, collagen-binding domain Adhesin YadA, collagen-binding domain 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 32
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 33
CheY-like Histidine-containing phosphotransfer domain, HPT domain 33
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
Lysozyme-like beta-lactamase/transpeptidase-like 32
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 32
PreATP-grasp domain Rudiment single hybrid motif 31
GroES-like NAD(P)-binding Rossmann-fold domains 31
Nucleic acid-binding proteins RuvA domain 2-like 33
TPR-like TPR-like 33
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 31
ACT-like NAD(P)-binding Rossmann-fold domains 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 32
Galactose-binding domain-like (Trans)glycosidases 33
PDZ domain-like PDZ domain-like 33
Subtilisin-like Autotransporter 31
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
ACT-like ACT-like 33
Phospholipase D/nuclease Phospholipase D/nuclease 33
Ribonuclease H-like DNA/RNA polymerases 32
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 33
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
TSP type-3 repeat beta-Roll 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 33
Adhesin YadA, collagen-binding domain Pili subunits 33
PLP-binding barrel Alanine racemase C-terminal domain-like 33
PurM N-terminal domain-like PurM C-terminal domain-like 32
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
CheY-like PYP-like sensor domain (PAS domain) 22
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 21
PDZ domain-like ClpP/crotonase 21
Aconitase iron-sulfur domain LeuD/IlvD-like 22
CBS-domain pair FAD-binding/transporter-associated domain-like 21
Thiolase-like Thiolase-like 21
TGS-like ACT-like 21
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 22
DNA methylase specificity domain DNA methylase specificity domain 22
CheY-like EAL domain-like 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
PA domain Zn-dependent exopeptidases 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
HD-domain/PDEase-like ACT-like 21
Single hybrid motif CoA-dependent acyltransferases 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
P-loop containing nucleoside triphosphate hydrolases MOP-like 21
Cupredoxins Cupredoxins 22
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 21
CheY-like CheY-like 22
HD-domain/PDEase-like Nucleotidyltransferase 21
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 21
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 22
Nucleotidyltransferase TGS-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 22
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 21
Nucleotide cyclase EAL domain-like 22
Nucleotidyltransferase ACT-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
CheY-like P-loop containing nucleoside triphosphate hydrolases 22
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
RuvA domain 2-like RuvA domain 2-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 22
HD-domain/PDEase-like TGS-like 21
Trypsin-like serine proteases PDZ domain-like 22
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 21
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 21
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 21
CheY-like Nucleotide cyclase 22
MFS general substrate transporter MFS general substrate transporter 21
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 21
Thioredoxin-like GST C-terminal domain-like 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 21
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 22
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 22
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 21
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 21
Carbamate kinase-like ACT-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 22
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Sporulation related repeat Sporulation related repeat 11
HprK N-terminal domain-like PEP carboxykinase-like 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Calcium-dependent phosphotriesterase CheY-like 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Thioredoxin-like HesB-like domain 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 11
Ribonuclease H-like RuvA domain 2-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
DNA-glycosylase Nudix 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Quinoprotein alcohol dehydrogenase-like Quinoprotein alcohol dehydrogenase-like 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
(Trans)glycosidases Anthrax protective antigen 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
PurS-like PurM C-terminal domain-like 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
Class II aaRS and biotin synthetases Translation proteins 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
UROD/MetE-like UROD/MetE-like 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
ACT-like Formyltransferase 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Class II aaRS and biotin synthetases GAD domain-like 11
PUA domain-like alpha/beta knot 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
PurS-like FGAM synthase PurL, linker domain 11
TSP type-3 repeat OmpA-like 11
Translation proteins PRC-barrel domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
L30e-like alpha/beta knot 11
4Fe-4S ferredoxins ADC-like 11
Carbamate kinase-like PUA domain-like 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
PHP domain-like Nucleic acid-binding proteins 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Bacterial muramidases Lysozyme-like 11
DNA clamp DNA clamp 11
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
(Trans)glycosidases Barwin-like endoglucanases 11
PHP14-like Phospholipase D/nuclease 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Ankyrin repeat Ankyrin repeat 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
MetI-like MetI-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
ACT-like PLP-binding barrel 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
GIY-YIG endonuclease RuvA domain 2-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
PurS-like PurM N-terminal domain-like 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 11
beta-N-acetylhexosaminidase-like domain (Trans)glycosidases 11
YrdC/RibB RibA-like 11
HesB-like domain Rhodanese/Cell cycle control phosphatase 11
Carbamate kinase-like Alanine racemase C-terminal domain-like 11
Carbamate kinase-like PLP-binding barrel 11
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 11
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
TGS-like Class II aaRS ABD-related 11
(Trans)glycosidases Carbohydrate-binding domain 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Putative DNA-binding domain Translation proteins 11
ClpP/crotonase ClpP/crotonase 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Flavoproteins Riboflavin synthase domain-like 11
Tex N-terminal region-like Ribonuclease H-like 11
Bacterial adhesins Bacterial adhesins 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
KorB DNA-binding domain-like C-terminal domain of transcriptional repressors 11
ACT-like Alanine racemase C-terminal domain-like 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
Calcium-dependent phosphotriesterase Homodimeric domain of signal transducing histidine kinase 11
Chorismate mutase II ACT-like 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
(Phosphotyrosine protein) phosphatases II Metallo-hydrolase/oxidoreductase 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
ACT-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
Nudix Thiamin phosphate synthase 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Carbamate kinase-like NAD(P)-binding Rossmann-fold domains 11
PreATP-grasp domain PreATP-grasp domain 11
Single hybrid motif Single hybrid motif 11
Single hybrid motif FAD/NAD(P)-binding domain 11
Homeodomain-like Homeodomain-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
CarD-like TRCF domain-like 11
Galactose mutarotase-like E set domains 11
6-phosphogluconate dehydrogenase C-terminal domain-like ACT-like 11
RuvA domain 2-like BRCT domain 11
Bet v1-like Probable bacterial effector-binding domain 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
FKBP-like FKBP-like 11
P-loop containing nucleoside triphosphate hydrolases Phospholipase D/nuclease 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Carbamate kinase-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
HAD-like Ribosomal protein S5 domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Starch-binding domain-like Porins 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
GroEL-intermediate domain like GroEL apical domain-like 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Ribosomal protein L6 Ribosomal protein L6 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
PapD-like Periplasmic chaperone C-domain 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
alpha/beta-Hydrolases alpha/beta-Hydrolases 11
Galactose-binding domain-like Galactose-binding domain-like 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
Leukotriene A4 hydrolase N-terminal domain ARM repeat 11
RNase III domain-like dsRNA-binding domain-like 11
Rhodanese/Cell cycle control phosphatase Activating enzymes of the ubiquitin-like proteins 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Glycoside hydrolase/deacetylase Caspase-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
Barwin-like endoglucanases Sporulation related repeat 11
Ribonuclease H-like HRDC-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
HesB-like domain Fe-S cluster assembly (FSCA) domain-like 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Duplicated hybrid motif beta-Roll 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
ParB/Sulfiredoxin C-terminal domain of transcriptional repressors 11
Glycoside hydrolase/deacetylase TPR-like 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
alpha-helical ferredoxin Nucleotide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
TGS-like Class II aaRS and biotin synthetases 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes CBS-domain pair 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Chorismate mutase II Periplasmic binding protein-like II 11
"Winged helix" DNA-binding domain GAF domain-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
PPK N-terminal domain-like PHP14-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Glycosyl hydrolases family 6, cellulases Carbohydrate-binding domain 11
Nucleotidylyl transferase YegP-like 11
Nucleic acid-binding proteins GAD domain-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
"Winged helix" DNA-binding domain Iron-dependent repressor protein, dimerization domain 11
CheW-like CheY-like 11
PYP-like sensor domain (PAS domain) Nucleotide cyclase 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Formyltransferase FMT C-terminal domain-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
CheY-like HD-domain/PDEase-like 11
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Globin-like Riboflavin synthase domain-like 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
PheT/TilS domain Putative DNA-binding domain 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
2Fe-2S ferredoxin-like ADC-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Tex N-terminal region-like RuvA domain 2-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Metalloproteases ("zincins"), catalytic domain ARM repeat 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Caspase-like TPR-like 11
(Trans)glycosidases PHL pollen allergen 11
SGNH hydrolase Autotransporter 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
YjeF N-terminal domain-like Ribokinase-like 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Zinc beta-ribbon DNA primase core 11
Thioredoxin-like TPR-like 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Nucleic acid-binding proteins PheT/TilS domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Calcium-dependent phosphotriesterase Calcium-dependent phosphotriesterase 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Periplasmic binding protein-like II ACT-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
MesJ substrate recognition domain-like PheT/TilS domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
TGS-like ThrRS/AlaRS common domain 11
HRDC-like HRDC-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Thioredoxin-like Rhodanese/Cell cycle control phosphatase 11
Galactose-binding domain-like Six-hairpin glycosidases 11
cAMP-binding domain-like "Winged helix" DNA-binding domain 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Translation proteins ThrRS/AlaRS common domain 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Macro domain-like Zn-dependent exopeptidases 11
HisI-like all-alpha NTP pyrophosphatases 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Thioredoxin-like Thioredoxin-like 11
Nucleic acid-binding proteins BRCT domain 11
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 11
PIN domain-like DNA/RNA polymerases 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
PK beta-barrel domain-like PK C-terminal domain-like 11
PurS-like Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
Nucleotidylyl transferase tRNA-binding arm 11
DNA primase core DNA primase DnaG, C-terminal domain 11
Hsp33 domain HSP33 redox switch-like 11
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
PIN domain-like Ribonuclease H-like 11
Barwin-like endoglucanases PHL pollen allergen 11
Translation proteins Translation proteins 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
OMPA-like TSP type-3 repeat 11
PYP-like sensor domain (PAS domain) EAL domain-like 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
Beta-D-glucan exohydrolase, C-terminal domain Anthrax protective antigen 11
PLP-dependent transferases PLP-dependent transferases 11
Calcium-dependent phosphotriesterase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
OMPA-like OmpA-like 11
Pseudouridine synthase PUA domain-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11

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