SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Thioalkalivibrio sp. K90mix

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

583 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2114
PYP-like sensor domain (PAS domain) Nucleotide cyclase 2017
Nucleotide cyclase EAL domain-like 1914
PYP-like sensor domain (PAS domain) EAL domain-like 129
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 1212
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 118
Actin-like ATPase domain Actin-like ATPase domain 113
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 105
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 104
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 102
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 94
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 94
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 94
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 94
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 84
CheY-like P-loop containing nucleoside triphosphate hydrolases 83
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 83
CheY-like Homeodomain-like 72
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 75
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 74
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 75
Cytochrome c Cytochrome c 72
P-loop containing nucleoside triphosphate hydrolases Translation proteins 75
GAF domain-like Nucleotide cyclase 77
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 74
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 73
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 64
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 62
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 61
ACT-like ACT-like 64
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
PYP-like sensor domain (PAS domain) GAF domain-like 55
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 52
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 54
Phospholipase D/nuclease Phospholipase D/nuclease 53
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 51
Ribosomal protein S5 domain 2-like P-loop containing nucleoside triphosphate hydrolases 55
PreATP-grasp domain Rudiment single hybrid motif 41
TrkA C-terminal domain-like TrkA C-terminal domain-like 42
GAF domain-like EAL domain-like 44
FKBP-like Triger factor/SurA peptide-binding domain-like 44
Calcium ATPase, transduction domain A HAD-like 43
Translation proteins EF-G C-terminal domain-like 43
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 43
CheY-like Nucleotide cyclase 44
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 41
HAD-like Calcium ATPase, transmembrane domain M 43
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 41
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 43
Cupredoxins Cupredoxins 43
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 41
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 43
cAMP-binding domain-like "Winged helix" DNA-binding domain 41
TPR-like TPR-like 44
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 43
Thioredoxin-like Six-hairpin glycosidases 32
Nucleotidyltransferase HD-domain/PDEase-like 32
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
Alpha-L RNA-binding motif Pseudouridine synthase 31
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 31
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 31
PLP-binding barrel Alanine racemase C-terminal domain-like 32
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 32
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 31
Homeodomain-like Ribonuclease H-like 31
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
PurM N-terminal domain-like PurM C-terminal domain-like 32
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 32
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
GroES-like NAD(P)-binding Rossmann-fold domains 31
Trypsin-like serine proteases PDZ domain-like 32
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 32
Nucleotidyltransferase ACT-like 32
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 33
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 31
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 32
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Nucleic acid-binding proteins RuvA domain 2-like 33
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 33
CheY-like EAL domain-like 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
Periplasmic binding protein-like II PYP-like sensor domain (PAS domain) 33
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 32
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 31
CheY-like PYP-like sensor domain (PAS domain) 33
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 32
Thioredoxin-like GST C-terminal domain-like 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 33
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 32
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 31
HD-domain/PDEase-like ACT-like 32
Periplasmic binding protein-like II Nucleotide cyclase 33
PDZ domain-like PDZ domain-like 32
CheY-like C-terminal effector domain of the bipartite response regulators 21
HD-domain/PDEase-like TGS-like 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 22
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
CheW-like CheY-like 22
CheY-like CheY-like 22
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
MetI-like MetI-like 22
ParB/Sulfiredoxin KorB DNA-binding domain-like 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Macro domain-like Zn-dependent exopeptidases 21
Aldolase post-HMGL domain-like 22
CBS-domain pair MgtE membrane domain-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 22
Single hybrid motif CoA-dependent acyltransferases 21
HAMP domain-like Nucleotide cyclase 22
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Lysozyme-like beta-lactamase/transpeptidase-like 22
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 21
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 21
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 21
HMA, heavy metal-associated domain HAD-like 22
Folate-binding domain Aminomethyltransferase beta-barrel domain 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 21
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 21
CheY-like GAF domain-like 22
HAMP domain-like PYP-like sensor domain (PAS domain) 22
Restriction endonuclease-like RuvA domain 2-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
RuvA domain 2-like BRCT domain 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 22
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
TGS-like ACT-like 21
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 21
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 22
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 22
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 21
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 21
Nucleotidyltransferase TGS-like 21
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 21
Thiolase-like Thiolase-like 21
cAMP-binding domain-like CBS-domain pair 22
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 21
Nucleic acid-binding proteins BRCT domain 22
P-loop containing nucleoside triphosphate hydrolases MOP-like 21
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 21
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
Homeodomain-like Homeodomain-like 22
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 22
PK beta-barrel domain-like PK C-terminal domain-like 21
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 21
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 21
MgtE N-terminal domain-like CBS-domain pair 21
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 21
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 22
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Histidine-containing phosphotransfer domain, HPT domain CheW-like 22
CBS-domain pair FAD-binding/transporter-associated domain-like 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 22
MgtE N-terminal domain-like MgtE membrane domain-like 21
Histidine-containing phosphotransfer domain, HPT domain CheY-like 22
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
DsbC/DsbG N-terminal domain-like Thioredoxin-like 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
EAL domain-like HD-domain/PDEase-like 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 11
Chorismate mutase II Periplasmic binding protein-like II 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Nqo1 FMN-binding domain-like alpha-helical ferredoxin 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
PPK N-terminal domain-like PHP14-like 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Rubredoxin-like FAD/NAD(P)-binding domain 11
Class II aaRS and biotin synthetases GAD domain-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Nucleic acid-binding proteins PheT/TilS domain 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Homodimeric domain of signal transducing histidine kinase CheY-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
HAMP domain-like EAL domain-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
DNA-glycosylase Nudix 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
YjeF N-terminal domain-like Ribokinase-like 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
Retrovirus zinc finger-like domains Retrovirus zinc finger-like domains 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
E set domains (Trans)glycosidases 11
Ribosomal protein L6 Ribosomal protein L6 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Nucleotide cyclase P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
HAMP domain-like PP2C-like 11
Chorismate mutase II ACT-like 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Protein kinase-like (PK-like) HD-domain/PDEase-like 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
PIN domain-like DNA/RNA polymerases 11
Carbamate kinase-like ACT-like 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
(Trans)glycosidases Glycosyl hydrolase domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
GroEL equatorial domain-like GroEL apical domain-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Bacterial muramidases Lysozyme-like 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Ribokinase-like Nucleotidylyl transferase 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Periplasmic binding protein-like II Lysozyme-like 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 11
Protein kinase-like (PK-like) GAF domain-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
LysM domain TPR-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
PIN domain-like Ribonuclease H-like 11
TGS-like Class II aaRS ABD-related 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
CBS-domain pair Nucleotidyltransferase 11
Homing endonucleases PFL-like glycyl radical enzymes 11
DinB/YfiT-like putative metalloenzymes C-type lectin-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
YrdC/RibB RibA-like 11
cAMP-binding domain-like Nucleotidyltransferase 11
HD-domain/PDEase-like GAF domain-like 11
cAMP-binding domain-like HD-domain/PDEase-like 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
GroEL-intermediate domain like GroEL apical domain-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
NTF2-like Nucleotide cyclase 11
Lysozyme-like LysM domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
WD40 repeat-like MetI-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Zinc beta-ribbon DNA primase core 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
alpha-helical ferredoxin Nucleotide-binding domain 11
PurS-like PurM N-terminal domain-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Translation proteins PRC-barrel domain 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Ribonuclease H-like HRDC-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Adenine nucleotide alpha hydrolases-like Rhodanese/Cell cycle control phosphatase 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
PheT/TilS domain Putative DNA-binding domain 11
HD-domain/PDEase-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
FKBP-like Rhodanese/Cell cycle control phosphatase 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Oxidoreductase molybdopterin-binding domain E set domains 11
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 11
PurS-like Class I glutamine amidotransferase-like 11
S-adenosyl-L-methionine-dependent methyltransferases P-loop containing nucleoside triphosphate hydrolases 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
RNase III domain-like dsRNA-binding domain-like 11
FMN-binding split barrel UbiD C-terminal domain-like 11
PUA domain-like Nucleotidylyl transferase 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
GAF domain-like Homodimeric domain of signal transducing histidine kinase 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
THUMP domain-like Rhodanese/Cell cycle control phosphatase 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
PurS-like PurM C-terminal domain-like 11
LysM domain LysM domain 11
Thioredoxin-like Thioredoxin-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Sensory domain-like HAMP domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
Periplasmic binding protein-like II ACT-like 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
DPP6 N-terminal domain-like alpha/beta-Hydrolases 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
GAF domain-like Homeodomain-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
RuBisCO, large subunit, small (N-terminal) domain RuBisCo, C-terminal domain 11
DNA clamp DNA clamp 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
CheY-like Methylesterase CheB, C-terminal domain 11
Protein kinase-like (PK-like) HAMP domain-like 11
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 11
PreATP-grasp domain PreATP-grasp domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Nucleotidylyl transferase tRNA-binding arm 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Hedgehog/intein (Hint) domain PFL-like glycyl radical enzymes 11
Nucleotidyltransferase Nucleotidyltransferase 11
Putative DNA-binding domain Translation proteins 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
Class II aaRS and biotin synthetases Translation proteins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
DNase I-like RuvA domain 2-like 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
ClpP/crotonase NfeD domain-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Trigger factor ribosome-binding domain FKBP-like 11
TPR-like Nucleotide cyclase 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
TGS-like Class II aaRS and biotin synthetases 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
UDP-Glycosyltransferase/glycogen phosphorylase HAD-like 11
L30e-like alpha/beta knot 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
THUMP domain-like Adenine nucleotide alpha hydrolases-like 11
E set domains Glycosyl hydrolase domain 11
TPR-like P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Phospholipase D/nuclease P-loop containing nucleoside triphosphate hydrolases 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Zn-dependent exopeptidases LysM domain 11
Single hybrid motif FAD/NAD(P)-binding domain 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Thioredoxin-like TPR-like 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
Actin-like ATPase domain HD-domain/PDEase-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
HRDC-like HRDC-like 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
GAF domain-like Phosphohistidine domain 11
post-HMGL domain-like Single hybrid motif 11
DNA methylase specificity domain DNA methylase specificity domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
PHP14-like Phospholipase D/nuclease 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
Hedgehog/intein (Hint) domain Homing endonucleases 11
Periplasmic binding protein-like II EAL domain-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
PurS-like FGAM synthase PurL, linker domain 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
DNA primase core DNA primase DnaG, C-terminal domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
EreA/ChaN-like PDZ domain-like 11
Nucleotide cyclase Nucleotide cyclase 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
PDZ domain-like ClpP/crotonase 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Translation proteins ThrRS/AlaRS common domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
CheC-like Surface presentation of antigens (SPOA) 11
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
"Winged helix" DNA-binding domain GAF domain-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
FliG FliG 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 11
Protein kinase-like (PK-like) Sensory domain-like 11
Hsp33 domain HSP33 redox switch-like 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Carbamate kinase-like PUA domain-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
PUA domain-like alpha/beta knot 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
TGS-like ThrRS/AlaRS common domain 11
GAF domain-like GAF domain-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Nudix Thiamin phosphate synthase 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Translation proteins Translation proteins 11
Nucleic acid-binding proteins GAD domain-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
"Winged helix" DNA-binding domain Rhodanese/Cell cycle control phosphatase 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
UDP-Glycosyltransferase/glycogen phosphorylase NAD(P)-binding Rossmann-fold domains 11
FKBP-like FKBP-like 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
ACT-like Formyltransferase 11
HprK N-terminal domain-like PEP carboxykinase-like 11
P-loop containing nucleoside triphosphate hydrolases Acyl-CoA N-acyltransferases (Nat) 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
P-loop containing nucleoside triphosphate hydrolases Sporulation related repeat 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Acyl-CoA N-acyltransferases (Nat) Carbon-nitrogen hydrolase 11
Hypothetical protein TM0160 PDZ domain-like 11
HCP-like TPR-like 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
P-loop containing nucleoside triphosphate hydrolases Microbial and mitochondrial ADK, insert "zinc finger" domain 11
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Periplasmic binding protein-like II GAF domain-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
lambda repressor-like DNA-binding domains LexA/Signal peptidase 11
E set domains E set domains 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Rhodanese/Cell cycle control phosphatase Metallo-hydrolase/oxidoreductase 11
Globin-like Riboflavin synthase domain-like 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Barwin-like endoglucanases Sporulation related repeat 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Class I glutamine amidotransferase-like Homeodomain-like 11
RuvA domain 2-like JAB1/MPN domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
L domain-like L domain-like 11
CarD-like TRCF domain-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Ribonuclease H-like DNA/RNA polymerases 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Formyltransferase FMT C-terminal domain-like 11
Aldolase Single hybrid motif 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11

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