SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Exiguobacterium sp. MH3

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

588 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 3013
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 259
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 156
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 145
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 144
GroES-like NAD(P)-binding Rossmann-fold domains 132
Actin-like ATPase domain Actin-like ATPase domain 135
CheY-like C-terminal effector domain of the bipartite response regulators 111
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 112
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 91
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 92
(Trans)glycosidases Glycosyl hydrolase domain 93
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 86
Nucleotide cyclase EAL domain-like 86
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 84
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 82
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 84
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 81
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 77
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 73
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 72
GAF domain-like Homodimeric domain of signal transducing histidine kinase 73
"Winged helix" DNA-binding domain Chorismate lyase-like 71
PYP-like sensor domain (PAS domain) Nucleotide cyclase 76
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 72
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 64
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 61
P-loop containing nucleoside triphosphate hydrolases Translation proteins 65
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 64
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 54
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 52
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 52
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 54
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 51
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 41
Phospholipase D/nuclease Phospholipase D/nuclease 42
Single hybrid motif CoA-dependent acyltransferases 41
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 41
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 44
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 43
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 42
PreATP-grasp domain Rudiment single hybrid motif 42
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 41
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 43
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 43
Thiolase-like Thiolase-like 41
PYP-like sensor domain (PAS domain) EAL domain-like 44
Alpha-L RNA-binding motif Pseudouridine synthase 41
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 44
CBS-domain pair FAD-binding/transporter-associated domain-like 41
HAMP domain-like PYP-like sensor domain (PAS domain) 43
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 41
lambda repressor-like DNA-binding domains TPR-like 41
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 43
Translation proteins EF-G C-terminal domain-like 43
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 44
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 41
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
PLP-binding barrel Alanine racemase C-terminal domain-like 32
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 31
P-loop containing nucleoside triphosphate hydrolases ACT-like 31
Calcium ATPase, transduction domain A HAD-like 32
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 31
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 31
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 31
Nucleic acid-binding proteins RuvA domain 2-like 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 31
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 33
E set domains (Trans)glycosidases 33
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 31
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 31
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 31
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 33
HAMP domain-like GAF domain-like 32
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 31
HAD-like Calcium ATPase, transmembrane domain M 32
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 33
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
PTS system IIB component-like Phoshotransferase/anion transport protein 32
cAMP-binding domain-like "Winged helix" DNA-binding domain 31
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 31
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 32
Hedgehog/DD-peptidase PGBD-like 32
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 32
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
Lysozyme-like beta-lactamase/transpeptidase-like 33
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 31
ParB/Sulfiredoxin KorB DNA-binding domain-like 21
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 22
MalF N-terminal region-like MetI-like 22
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 21
SacY-like RNA-binding domain PTS-regulatory domain, PRD 22
P-loop containing nucleoside triphosphate hydrolases MOP-like 21
Trypsin-like serine proteases PDZ domain-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 22
PreATP-grasp domain PreATP-grasp domain 22
Phosphoenolpyruvate/pyruvate domain Phosphohistidine domain 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 21
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
Nucleic acid-binding proteins Ribonuclease H-like 22
GAF domain-like Nucleotide cyclase 22
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 21
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 22
MetI-like Periplasmic binding protein-like II 21
Peptide methionine sulfoxide reductase Mss4-like 21
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 22
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 21
PTS-regulatory domain, PRD PTS-regulatory domain, PRD 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 22
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 22
PurM N-terminal domain-like PurM C-terminal domain-like 22
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 21
Translation proteins ThrRS/AlaRS common domain 22
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 22
"Winged helix" DNA-binding domain CBS-domain pair 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
Globin-like Methyl-accepting chemotaxis protein (MCP) signaling domain 21
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
Ribosomal protein S5 domain 2-like EF-G C-terminal domain-like 22
Rhodanese/Cell cycle control phosphatase SirA-like 22
FAD/NAD-linked reductases, dimerisation (C-terminal) domain Rhodanese/Cell cycle control phosphatase 22
CheC-like Surface presentation of antigens (SPOA) 22
GAF domain-like "Winged helix" DNA-binding domain 22
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 22
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 21
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 22
FAD/NAD(P)-binding domain Rhodanese/Cell cycle control phosphatase 22
Enolase N-terminal domain-like Enolase C-terminal domain-like 21
L30e-like alpha/beta knot 21
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 22
Homeodomain-like Homeodomain-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 21
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 22
FKBP-like Triger factor/SurA peptide-binding domain-like 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 22
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
PTS-regulatory domain, PRD Phoshotransferase/anion transport protein 21
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 22
Pectin lyase-like Pectin lyase-like 22
PTS-regulatory domain, PRD PTS system IIB component-like 21
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 21
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 22
Glucose permease domain IIB Duplicated hybrid motif 22
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 21
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
CheY-binding domain of CheA ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
HD-domain/PDEase-like TGS-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
GIY-YIG endonuclease RuvA domain 2-like 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
Translation proteins PRC-barrel domain 11
CBS-domain pair Thioesterase/thiol ester dehydrase-isomerase 11
Nucleotidylyl transferase tRNA-binding arm 11
Nucleotide-binding domain ISP domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
EAL domain-like Sensory domain-like 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
HD-domain/PDEase-like ACT-like 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Rhodanese/Cell cycle control phosphatase DsrEFH-like 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
Glycoside hydrolase/deacetylase LysM domain 11
CheY-like Homeodomain-like 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
PDZ domain-like Ribosomal protein S5 domain 2-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Cupredoxins Cytochrome c 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidyltransferase ACT-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Starch-binding domain-like Starch-binding domain-like 11
Class II aaRS and biotin synthetases SufE/NifU 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
HMA, heavy metal-associated domain HAD-like 11
CBS-domain pair ACT-like 11
Sec63 N-terminal domain-like PHP domain-like 11
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 11
MgtE N-terminal domain-like CBS-domain pair 11
FAD/NAD-linked reductases, dimerisation (C-terminal) domain DsrEFH-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Starch-binding domain-like E set domains 11
Subtilisin-like PA domain 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
Trigger factor ribosome-binding domain FKBP-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Histidine-containing phosphotransfer domain, HPT domain CheY-binding domain of CheA 11
CheW-like CheY-like 11
LysM domain PGBD-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
PDZ domain-like PGBD-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
GroES-like GroES-like 11
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 11
"Winged helix" DNA-binding domain Thioesterase/thiol ester dehydrase-isomerase 11
RuBisCO, large subunit, small (N-terminal) domain RuBisCo, C-terminal domain 11
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
ALDH-like Dehydroquinate synthase-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
PreATP-grasp domain post-HMGL domain-like 11
(Trans)glycosidases Cyclophilin-like 11
post-HMGL domain-like Single hybrid motif 11
PYP-like sensor domain (PAS domain) Homeodomain-like 11
Nucleic acid-binding proteins GAD domain-like 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Starch-binding domain-like (Trans)glycosidases 11
Nucleotidyltransferase PHP domain-like 11
ACT-like ACT-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Putative DNA-binding domain Cobalamin (vitamin B12)-binding domain 11
PK C-terminal domain-like Phosphohistidine domain 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
"Winged helix" DNA-binding domain PLP-dependent transferases 11
Concanavalin A-like lectins/glucanases Galactose-binding domain-like 11
Nucleic acid-binding proteins PHP domain-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
RuvA domain 2-like BRCT domain 11
Homeodomain-like SIS domain 11
"Winged helix" DNA-binding domain PRTase-like 11
TGS-like Class II aaRS ABD-related 11
Nucleic acid-binding proteins BRCT domain 11
Putative DNA-binding domain Antibiotic binding domain of TipA-like multidrug resistance regulators 11
Galactose mutarotase-like Six-hairpin glycosidases 11
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 11
RNase III domain-like dsRNA-binding domain-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
Carbamate kinase-like ACT-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
Penicillin binding protein dimerisation domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Rudiment single hybrid motif post-HMGL domain-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Collagen-binding domain Collagen-binding domain 11
Chaperone J-domain Chaperone J-domain 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
Molybdenum cofactor biosynthesis proteins CinA-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
Phage tail proteins Barwin-like endoglucanases 11
Tex N-terminal region-like RuvA domain 2-like 11
DPP6 N-terminal domain-like Invasin/intimin cell-adhesion fragments 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
TGS-like ThrRS/AlaRS common domain 11
"Winged helix" DNA-binding domain Iron-dependent repressor protein, dimerization domain 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
HD-domain/PDEase-like Nucleotidyltransferase 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
NAD(P)-binding Rossmann-fold domains P-loop containing nucleoside triphosphate hydrolases 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Rudiment single hybrid motif Single hybrid motif 11
lambda repressor-like DNA-binding domains RmlC-like cupins 11
PK beta-barrel domain-like Phosphohistidine domain 11
Nucleotide-diphospho-sugar transferases UDP-Glycosyltransferase/glycogen phosphorylase 11
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
CarD-like TRCF domain-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
FliG FliG 11
Thioredoxin-like Thioredoxin-like 11
FAD/NAD-linked reductases, dimerisation (C-terminal) domain SirA-like 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
NTF2-like Penicillin binding protein dimerisation domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
PreATP-grasp domain Single hybrid motif 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
CheY-binding domain of CheA CheW-like 11
Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Class II aaRS and biotin synthetases Translation proteins 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
PreATP-grasp domain Aldolase 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
Sensory domain-like PYP-like sensor domain (PAS domain) 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Barwin-like endoglucanases Duplicated hybrid motif 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Ribonuclease H-like P-loop containing nucleoside triphosphate hydrolases 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
P-loop containing nucleoside triphosphate hydrolases Obg GTP-binding protein C-terminal domain 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Hypothetical protein SAV1430 ARM repeat 11
PIN domain-like Ribonuclease H-like 11
DNA polymerase beta, N-terminal domain-like PHP domain-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Nucleic acid-binding proteins PheT/TilS domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
"Winged helix" DNA-binding domain NAD(P)-binding Rossmann-fold domains 11
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Aldolase AFP III-like domain 11
DNA clamp DNA clamp 11
Ribonuclease H-like RuvA domain 2-like 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Peptide deformylase FMT C-terminal domain-like 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
FAD/NAD(P)-binding domain SirA-like 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Serine metabolism enzymes domain ACT-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Tropomyosin Duplicated hybrid motif 11
NAD(P)-binding Rossmann-fold domains Homeodomain-like 11
Nucleotidyltransferase TGS-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 11
YjeF N-terminal domain-like Ribokinase-like 11
NAD(P)-binding Rossmann-fold domains PYP-like sensor domain (PAS domain) 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
GAF domain-like PYP-like sensor domain (PAS domain) 11
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Class I glutamine amidotransferase-like 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
PHP14-like Phospholipase D/nuclease 11
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
SpoIIaa-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 11
EAL domain-like HD-domain/PDEase-like 11
Dimeric alpha+beta barrel Nudix 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
DNA primase core N-terminal domain of DnaB helicase 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
(Trans)glycosidases Class I glutamine amidotransferase-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
PPK N-terminal domain-like PHP14-like 11
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Bacterial fluorinating enzyme, N-terminal domain Bacterial fluorinating enzyme, C-terminal domain 11
Tetrapyrrole methylase all-alpha NTP pyrophosphatases 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Zinc beta-ribbon N-terminal domain of DnaB helicase 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Rudiment single hybrid motif Aldolase 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Cytochrome c 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
TPR-like TPR-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
PIN domain-like DNA/RNA polymerases 11
DNA-glycosylase Nudix 11
"Winged helix" DNA-binding domain C-terminal domain of arginine repressor 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
6-phosphogluconate dehydrogenase C-terminal domain-like ClpP/crotonase 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Hsp33 domain HSP33 redox switch-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
CheY-binding domain of CheA Homodimeric domain of signal transducing histidine kinase 11
beta-lactamase/transpeptidase-like Penicillin-binding protein 2x (pbp-2x), c-terminal domain 11
HprK N-terminal domain-like Thioesterase/thiol ester dehydrase-isomerase 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
Acyl-CoA N-acyltransferases (Nat) PLP-dependent transferases 11
SirA-like DsrEFH-like 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
Aldolase Single hybrid motif 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
Peptide deformylase Formyltransferase 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Sec63 N-terminal domain-like Nucleotidyltransferase 11
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Zinc beta-ribbon DNA primase core 11
DNA repair protein MutS, domain III SMR domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Families 57/38 glycoside transferase middle domain UDP-Glycosyltransferase/glycogen phosphorylase 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
DeoB insert domain-like Alkaline phosphatase-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
NAD(P)-binding Rossmann-fold domains ClpP/crotonase 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Class I glutamine amidotransferase-like Glycoside hydrolase/deacetylase 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Thioredoxin-like Six-hairpin glycosidases 11
GroEL-intermediate domain like GroEL apical domain-like 11
Ribonuclease H-like DNA/RNA polymerases 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Respiratory nitrate reductase 1 gamma chain alpha-helical ferredoxin 11
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 11
Glycoside hydrolase/deacetylase UDP-Glycosyltransferase/glycogen phosphorylase 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Homeodomain-like "Helical backbone" metal receptor 11
TGS-like ACT-like 11
Invasin/intimin cell-adhesion fragments Collagen-binding domain 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Phage tail proteins Duplicated hybrid motif 11
"Winged helix" DNA-binding domain Putative transcriptional regulator TM1602, C-terminal domain 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Globin-like Riboflavin synthase domain-like 11
Macro domain-like Zn-dependent exopeptidases 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
Tex N-terminal region-like Ribonuclease H-like 11
Rhodanese/Cell cycle control phosphatase Metallo-hydrolase/oxidoreductase 11
DNA polymerase beta, N-terminal domain-like Sec63 N-terminal domain-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
FAD/NAD(P)-binding domain DsrEFH-like 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
CheY-like Nucleotide cyclase 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Trypsin-like serine proteases Collagen-binding domain 11
PHP domain-like Ribonuclease H-like 11
Galactose-binding domain-like Galactose-binding domain-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
HprK N-terminal domain-like PEP carboxykinase-like 11
MFS general substrate transporter MFS general substrate transporter 11
GAF domain-like EAL domain-like 11
RuvA domain 2-like RuvA domain 2-like 11
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
PUA domain-like alpha/beta knot 11
YrdC/RibB RibA-like 11
Aldolase post-HMGL domain-like 11
PDZ domain-like ClpP/crotonase 11
Sensory domain-like HAMP domain-like 11
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
GroEL equatorial domain-like GroEL apical domain-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
LysM domain LysM domain 11
Translation proteins Translation proteins 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Glutathione synthetase ATP-binding domain-like Aldolase 11
HprK N-terminal domain-like CBS-domain pair 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Obg GTP-binding protein N-terminal domain Obg GTP-binding protein C-terminal domain 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
YajQ-like YajQ-like 11
DinB/YfiT-like putative metalloenzymes C-type lectin-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Resolvase-like Homeodomain-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Homeodomain-like Probable bacterial effector-binding domain 11
ClpP/crotonase PGBD-like 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LD-carboxypeptidase A C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Formyltransferase FMT C-terminal domain-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 11
HD-domain/PDEase-like HD-domain/PDEase-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Invasin/intimin cell-adhesion fragments Trypsin-like serine proteases 11
NTF2-like beta-lactamase/transpeptidase-like 11
Chorismate mutase II Aldolase 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
Ribosomal protein L6 Ribosomal protein L6 11
beta-lactamase/transpeptidase-like Fibronectin type III 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like post-HMGL domain-like 11
Hedgehog/DD-peptidase LysM domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III TK C-terminal domain-like 11
CBS-domain pair MgtE membrane domain-like 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
PheT/TilS domain Putative DNA-binding domain 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
"Winged helix" DNA-binding domain HprK N-terminal domain-like 11
Phospholipase D/nuclease P-loop containing nucleoside triphosphate hydrolases 11
Lysozyme-like Fibronectin type III 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III Thiamin diphosphate-binding fold (THDP-binding) 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
TGS-like Class II aaRS and biotin synthetases 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Beta-D-glucan exohydrolase, C-terminal domain (Trans)glycosidases 11

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