SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Methylobacterium nodulans ORS 2060

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


Add or remove domain pairs

The links below permit the addition or removal of specific sets of domain combination pairs.


Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Add or remove genomes

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Add or remove genomes:
Include genomes:
Exclude genomes:


Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

772 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 791
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 6032
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 4015
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 364
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 3222
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 3120
CheY-like C-terminal effector domain of the bipartite response regulators 314
Homodimeric domain of signal transducing histidine kinase CheY-like 3120
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 2919
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 282
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 273
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 275
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 2622
cAMP-binding domain-like "Winged helix" DNA-binding domain 262
GroES-like NAD(P)-binding Rossmann-fold domains 254
Thioredoxin-like GST C-terminal domain-like 222
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 216
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 219
PYP-like sensor domain (PAS domain) CheY-like 2113
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 208
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 208
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 204
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 208
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 208
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 208
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 194
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 177
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 166
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 164
Thiolase-like Thiolase-like 141
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 133
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 132
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 131
beta-Roll beta-Roll 139
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 135
Calcium ATPase, transduction domain A HAD-like 126
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 122
Enolase N-terminal domain-like Enolase C-terminal domain-like 121
HAD-like Calcium ATPase, transmembrane domain M 126
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 126
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 115
Homeodomain-like Homeodomain-like 115
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 115
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 116
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 104
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 101
P-loop containing nucleoside triphosphate hydrolases MOP-like 101
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 101
TPR-like TPR-like 104
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 106
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 108
Actin-like ATPase domain Actin-like ATPase domain 104
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 93
"Winged helix" DNA-binding domain GAF domain-like 91
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 94
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 93
"Winged helix" DNA-binding domain PLP-dependent transferases 81
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 83
Lysozyme-like beta-lactamase/transpeptidase-like 84
CheY-like P-loop containing nucleoside triphosphate hydrolases 83
HlyD-like secretion proteins HlyD-like secretion proteins 84
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 83
P-loop containing nucleoside triphosphate hydrolases Translation proteins 86
ISP domain Bet v1-like 72
(Trans)glycosidases Glycosyl hydrolase domain 76
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 72
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 77
lambda repressor-like DNA-binding domains LexA/Signal peptidase 71
Trypsin-like serine proteases PDZ domain-like 72
Homeodomain-like Ribonuclease H-like 71
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 73
Cytochrome c Cytochrome c 73
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 75
GAF domain-like Homodimeric domain of signal transducing histidine kinase 66
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 66
Histidine-containing phosphotransfer domain, HPT domain CheY-like 66
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 63
Nucleotide cyclase EAL domain-like 63
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 62
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 61
TPR-like Caspase-like 63
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
CheY-like Homeodomain-like 62
PreATP-grasp domain Rudiment single hybrid motif 63
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 64
Nucleic acid-binding proteins Nucleic acid-binding proteins 65
CheY-like CheY-like 65
Nucleotide cyclase TPR-like 52
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 52
CBS-domain pair FAD-binding/transporter-associated domain-like 51
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 54
Formate dehydrogenase/DMSO reductase, domains 1-3 4Fe-4S ferredoxins 54
RmlC-like cupins Homeodomain-like 52
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 52
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 51
PYP-like sensor domain (PAS domain) GAF domain-like 55
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 54
PK beta-barrel domain-like PK C-terminal domain-like 51
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 51
ParB/Sulfiredoxin KorB DNA-binding domain-like 51
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 51
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 52
"Winged helix" DNA-binding domain Chorismate lyase-like 52
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 52
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 51
Oxidoreductase molybdopterin-binding domain E set domains 52
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 52
MoeA N-terminal region -like MoeA C-terminal domain-like 52
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 51
CheY-like GAF domain-like 55
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 54
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 51
Single hybrid motif CoA-dependent acyltransferases 51
Class I glutamine amidotransferase-like Homeodomain-like 51
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 51
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 54
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 52
Alpha-L RNA-binding motif Pseudouridine synthase 43
Pectin lyase-like beta-Roll 42
Nucleotide-diphospho-sugar transferases RmlC-like cupins 41
FKBP-like Triger factor/SurA peptide-binding domain-like 43
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 43
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 43
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 43
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 41
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 43
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 41
EF-G C-terminal domain-like EF-G C-terminal domain-like 43
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 41
Nqo1 middle domain-like Nqo1C-terminal domain-like 43
PLP-binding barrel Alanine racemase C-terminal domain-like 41
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 43
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 42
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 41
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 41
lambda repressor-like DNA-binding domains RmlC-like cupins 41
Regulatory protein AraC Homeodomain-like 43
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 42
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 42
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 43
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 43
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 43
Translation proteins EF-G C-terminal domain-like 43
ADC-like 4Fe-4S ferredoxins 43
E set domains (Trans)glycosidases 44
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 42
Resolvase-like Homeodomain-like 41
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 41
PurM N-terminal domain-like PurM C-terminal domain-like 42
PGBD-like L,D-transpeptidase catalytic domain-like 42
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 41
MetI-like MetI-like 42
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 41
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 33
CheY-like Methylesterase CheB, C-terminal domain 32
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 32
PYP-like sensor domain (PAS domain) EAL domain-like 31
Histidine-containing phosphotransfer domain, HPT domain CheW-like 33
Galactose mutarotase-like E set domains 31
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 32
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 31
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 31
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 31
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 31
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Cupredoxins Cupredoxins 32
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
Thioredoxin-like Nqo1C-terminal domain-like 32
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 31
2Fe-2S ferredoxin-like ADC-like 32
Formyltransferase FMT C-terminal domain-like 31
Thioredoxin-like Nqo1 FMN-binding domain-like 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 31
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 31
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 33
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 31
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 33
Nucleic acid-binding proteins RuvA domain 2-like 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
NAD(P)-binding Rossmann-fold domains ACT-like 33
Thioredoxin-like Nqo1 middle domain-like 32
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 33
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 33
Lysozyme-like PGBD-like 31
JAB1/MPN domain Cysteine proteinases 31
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 31
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 31
Folate-binding domain Aminomethyltransferase beta-barrel domain 32
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
UDP-Glycosyltransferase/glycogen phosphorylase Nucleotide-diphospho-sugar transferases 33
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 31
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 31
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 31
FAD/NAD(P)-binding domain Thioredoxin-like 31
GroEL-intermediate domain like GroEL apical domain-like 31
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 32
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 32
(Trans)glycosidases (Trans)glycosidases 33
FAD/NAD(P)-binding domain FMN-linked oxidoreductases 32
ACT-like ACT-like 33
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 31
E set domains Glycosyl hydrolase domain 33
GroEL equatorial domain-like GroEL-intermediate domain like 31
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 31
GroEL equatorial domain-like GroEL apical domain-like 31
PYP-like sensor domain (PAS domain) Nucleotide cyclase 31
FAD-linked reductases, C-terminal domain Thioredoxin-like 31
Phospholipase D/nuclease Phospholipase D/nuclease 33
PDZ domain-like PDZ domain-like 31
FMN-binding split barrel UbiD C-terminal domain-like 22
Ferritin-like Calcium ATPase, transduction domain A 21
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 22
GAF domain-like GAF domain-like 22
Lysozyme-like Staphylococcal nuclease 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
CO dehydrogenase ISP C-domain like CO dehydrogenase molybdoprotein N-domain-like 21
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
L30e-like alpha/beta knot 21
HAMP domain-like Nucleotide cyclase 22
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 22
Globin-like Riboflavin synthase domain-like 21
Clc chloride channel CBS-domain pair 21
Cupredoxins Cytochrome c 22
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 21
Translation proteins Ribosomal protein S5 domain 2-like 21
Sigma3 and sigma4 domains of RNA polymerase sigma factors NTF2-like 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
TPR-like S-adenosyl-L-methionine-dependent methyltransferases 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 22
Trimeric LpxA-like enzymes Trimeric LpxA-like enzymes 22
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
beta-lactamase/transpeptidase-like Staphylococcal nuclease 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
cAMP-binding domain-like FabD/lysophospholipase-like 21
Acetyl-CoA synthetase-like Glycerol-3-phosphate (1)-acyltransferase 22
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 21
Flavoproteins Riboflavin synthase domain-like 21
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
ClpP/crotonase ClpP/crotonase 21
Trypsin-like serine proteases His-Me finger endonucleases 22
AF0104/ALDC/Ptd012-like AF0104/ALDC/Ptd012-like 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 22
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 22
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 21
CheY-like HD-domain/PDEase-like 21
P-loop containing nucleoside triphosphate hydrolases CarD-like 22
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 21
CarD-like TRCF domain-like 22
Ferritin-like HAD-like 21
PH0987 N-terminal domain-like Cyclophilin-like 21
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 22
Putative DNA-binding domain Ribonuclease H-like 21
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 21
HMA, heavy metal-associated domain HAD-like 22
RuBisCO, large subunit, small (N-terminal) domain RuBisCo, C-terminal domain 21
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 22
lambda repressor-like DNA-binding domains Homeodomain-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
FAD/NAD(P)-binding domain Folate-binding domain 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 22
CheW-like CheW-like 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
ACP-like Acetyl-CoA synthetase-like 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
Nucleotidyltransferase ACT-like 22
2Fe-2S ferredoxin-like Molybdenum cofactor-binding domain 21
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 22
CheY-like Nucleotide cyclase 22
2Fe-2S ferredoxin-like alpha-helical ferredoxin 21
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 21
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Nucleotide-diphospho-sugar transferases S-adenosyl-L-methionine-dependent methyltransferases 22
Ferritin-like Calcium ATPase, transmembrane domain M 21
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Phage tail proteins Phage tail proteins 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
Aspartate/glutamate racemase Aspartate/glutamate racemase 21
Aconitase iron-sulfur domain LeuD/IlvD-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Galactose mutarotase-like Six-hairpin glycosidases 21
Methyl-accepting chemotaxis protein (MCP) signaling domain Methyl-accepting chemotaxis protein (MCP) signaling domain 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 22
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 22
Homodimeric domain of signal transducing histidine kinase CheW-like 22
Glutathione synthetase ATP-binding domain-like Acyl-CoA N-acyltransferases (Nat) 22
CheW-like CheY-like 22
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
2Fe-2S ferredoxin-like CO dehydrogenase molybdoprotein N-domain-like 21
CO dehydrogenase ISP C-domain like Molybdenum cofactor-binding domain 21
PUA domain-like alpha/beta knot 11
PreATP-grasp domain PreATP-grasp domain 11
DHS-like NAD/FAD-binding domain DHS-like NAD/FAD-binding domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
PK beta-barrel domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
YlxR-like L30e-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
ClpP/crotonase NfeD domain-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Nucleotidyltransferase TGS-like 11
Radical SAM enzymes Nitrogenase accessory factor-like 11
2Fe-2S ferredoxin-like Nucleotide cyclase 11
ACP-like Trimeric LpxA-like enzymes 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Adenine nucleotide alpha hydrolases-like GAF domain-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Carbamate kinase-like ACT-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Carbamate kinase-like PUA domain-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Translation proteins Periplasmic binding protein-like II 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
Nucleotide cyclase SMAD/FHA domain 11
TGS-like ACT-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain TPR-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
HD-domain/PDEase-like TGS-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Homeodomain-like ALDH-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Nucleotidylyl transferase Riboflavin kinase-like 11
L domain-like Protein kinase-like (PK-like) 11
FabD/lysophospholipase-like ACP-like 11
PIN domain-like Ribonuclease H-like 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors TPR-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Thioredoxin-like TPR-like 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
Nucleic acid-binding proteins BRCT domain 11
Methyl-accepting chemotaxis protein (MCP) signaling domain GAF domain-like 11
Thiolase-like FabD/lysophospholipase-like 11
Concanavalin A-like lectins/glucanases Metallo-dependent phosphatases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Nucleotidyltransferase substrate binding subunit/domain Poly A polymerase C-terminal region-like 11
Sigma2 domain of RNA polymerase sigma factors TPR-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
P-loop containing nucleoside triphosphate hydrolases TPR-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Hsp33 domain HSP33 redox switch-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
FabD/lysophospholipase-like S-adenosyl-L-methionine-dependent methyltransferases 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Bet v1-like FMN-binding split barrel 11
Cdc48 domain 2-like P-loop containing nucleoside triphosphate hydrolases 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
Sigma2 domain of RNA polymerase sigma factors NTF2-like 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
NAD(P)-binding Rossmann-fold domains MurD-like peptide ligases, peptide-binding domain 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Glycosyl hydrolase domain Protein kinase-like (PK-like) 11
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
PLP-dependent transferases PLP-dependent transferases 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
DinB/YfiT-like putative metalloenzymes C-type lectin-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Acetyl-CoA synthetase-like Trimeric LpxA-like enzymes 11
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Metallo-hydrolase/oxidoreductase GAF domain-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Thiolase-like S-adenosyl-L-methionine-dependent methyltransferases 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
PGBD-like Trypsin-like serine proteases 11
PHP domain-like AF1531-like 11
Single hybrid motif Thiamin diphosphate-binding fold (THDP-binding) 11
HAMP domain-like CheY-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
OMPA-like OMPA-like 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
Methylesterase CheB, C-terminal domain Chemotaxis receptor methyltransferase CheR, N-terminal domain 11
Tex N-terminal region-like RuvA domain 2-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
MoeA N-terminal region -like Periplasmic binding protein-like II 11
HD-domain/PDEase-like Nucleotidyltransferase 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Tetracyclin repressor-like, C-terminal domain ALDH-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 11
Translation proteins Translation proteins 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase S-adenosyl-L-methionine-dependent methyltransferases 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
FAD-linked oxidoreductase ALDH-like 11
Tex N-terminal region-like Ribonuclease H-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
Homocysteine S-methyltransferase Methionine synthase domain 11
WD40 repeat-like Cytochrome c 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
PLC-like phosphodiesterases Metallo-dependent phosphatases 11
Class II aaRS and biotin synthetases Translation proteins 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
NAD(P)-binding Rossmann-fold domains Citrate synthase 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
gp5 N-terminal domain-like Phage fibre proteins 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
SIS domain CBS-domain pair 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Poly A polymerase C-terminal region-like ACT-like 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 11
Formylmethanofuran:tetrahydromethanopterin formyltransferase Formylmethanofuran:tetrahydromethanopterin formyltransferase 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
PreATP-grasp domain Single hybrid motif 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
Adhesin YadA, collagen-binding domain Adhesin YadA, collagen-binding domain 11
Methylesterase CheB, C-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Aldolase SIS domain 11
UraD-Like Transthyretin (synonym: prealbumin) 11
Nucleic acid-binding proteins PheT/TilS domain 11
beta-Barrel protease inhibitors beta-Barrel protease inhibitors 11
Metallo-dependent hydrolases "Winged helix" DNA-binding domain 11
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
GroES-like GroES-like 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
dUTPase-like dUTPase-like 11
SGNH hydrolase Integrin alpha N-terminal domain 11
GAF domain-like Homeodomain-like 11
CO dehydrogenase molybdoprotein N-domain-like Bet v1-like 11
cAMP-binding domain-like CBS-domain pair 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
beta-sandwich domain of Sec23/24 OmpA-like 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
GAF domain-like Phosphohistidine domain 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Ribonuclease H-like DNA/RNA polymerases 11
Hypothetical protein YwqG Hypothetical protein YwqG 11
Integrin alpha N-terminal domain Integrin alpha N-terminal domain 11
UDP-Glycosyltransferase/glycogen phosphorylase S-adenosyl-L-methionine-dependent methyltransferases 11
Phase 1 flagellin Phase 1 flagellin 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Class II aaRS and biotin synthetases GAD domain-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
MFS general substrate transporter Acetyl-CoA synthetase-like 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
MgtE N-terminal domain-like CBS-domain pair 11
Sensory domain-like HAMP domain-like 11
RuvA domain 2-like BRCT domain 11
Translation proteins PRC-barrel domain 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Concanavalin A-like lectins/glucanases Concanavalin A-like lectins/glucanases 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
NAD(P)-binding Rossmann-fold domains ACP-like 11
Homeodomain-like SIS domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Thioesterase/thiol ester dehydrase-isomerase Isocitrate/Isopropylmalate dehydrogenase-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Fumarate reductase respiratory complex transmembrane subunits 2Fe-2S ferredoxin-like 11
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
FliG FliG 11
Transmembrane di-heme cytochromes CBD9-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
Zinc beta-ribbon DNA primase core 11
Concanavalin A-like lectins/glucanases beta-Roll 11
Thiolase-like ACP-like 11
DNase I-like beta-Roll 11
Periplasmic binding protein-like II ACT-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
Single hybrid motif TK C-terminal domain-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase GroES-like 11
Bacterial muramidases Lysozyme-like 11
Nucleotidylyl transferase tRNA-binding arm 11
Molybdenum cofactor biosynthesis proteins Periplasmic binding protein-like II 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain Periplasmic binding protein-like II 11
lambda repressor-like DNA-binding domains P-loop containing nucleoside triphosphate hydrolases 11
ParB/Sulfiredoxin S-adenosyl-L-methionine-dependent methyltransferases 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain PYP-like sensor domain (PAS domain) 11
ACP-like Glycerol-3-phosphate (1)-acyltransferase 11
Tetrahydrobiopterin biosynthesis enzymes-like Tetrahydrobiopterin biosynthesis enzymes-like 11
Metallo-hydrolase/oxidoreductase CheY-like 11
FabD/lysophospholipase-like GroES-like 11
Phage tail proteins Phage fibre proteins 11
TGS-like Class II aaRS and biotin synthetases 11
alpha-helical ferredoxin ARM repeat 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Concanavalin A-like lectins/glucanases PLC-like phosphodiesterases 11
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
PLC-like phosphodiesterases beta-Roll 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Serine metabolism enzymes domain ACT-like 11
CBS-domain pair MgtE membrane domain-like 11
Heme-dependent peroxidases Cytochrome P450 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Nucleotidyltransferase Nucleotidyltransferase 11
Ribosomal protein L6 Ribosomal protein L6 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Soluble quinoprotein glucose dehydrogenase Cytochrome c 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Caspase-like C-type lectin-like 11
Trigger factor ribosome-binding domain FKBP-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
GroES-like ACP-like 11
Methyl-accepting chemotaxis protein (MCP) signaling domain PilZ domain-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
S-adenosyl-L-methionine-dependent methyltransferases GroES-like 11
Metallo-dependent hydrolases Chorismate lyase-like 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
LysM domain Duplicated hybrid motif 11
CRISPR-associated protein CRISPR-associated protein 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Macro domain-like Zn-dependent exopeptidases 11
HD-domain/PDEase-like ACT-like 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
RuvA domain 2-like JAB1/MPN domain 11
Thiolase-like NAD(P)-binding Rossmann-fold domains 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
TPR-like Terpenoid cyclases/Protein prenyltransferases 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
UDP-Glycosyltransferase/glycogen phosphorylase Glycoside hydrolase/deacetylase 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
RuvA domain 2-like RuvA domain 2-like 11
YjeF N-terminal domain-like Ribokinase-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
HCP-like HCP-like 11
PHP14-like Phospholipase D/nuclease 11
PDZ domain-like ClpP/crotonase 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Methyl-accepting chemotaxis protein (MCP) signaling domain Homodimeric domain of signal transducing histidine kinase 11
Nucleotide-binding domain Nucleotide-binding domain 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 11
Dimeric alpha+beta barrel Dimeric alpha+beta barrel 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Creatinase/prolidase N-terminal domain Creatinase/prolidase N-terminal domain 11
RNase III domain-like dsRNA-binding domain-like 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Methyl-accepting chemotaxis protein (MCP) signaling domain CheY-like 11
ADC-like P-loop containing nucleoside triphosphate hydrolases 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
S-adenosyl-L-methionine-dependent methyltransferases EreA/ChaN-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 11
TGS-like Class II aaRS ABD-related 11
(Trans)glycosidases Glycoside hydrolase/deacetylase 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
TTHA1013/TTHA0281-like lambda repressor-like DNA-binding domains 11
Translation proteins ThrRS/AlaRS common domain 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Nucleotide cyclase P-loop containing nucleoside triphosphate hydrolases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
PK beta-barrel domain-like 2Fe-2S ferredoxin-like 11
Methylesterase CheB, C-terminal domain PYP-like sensor domain (PAS domain) 11
alpha-helical ferredoxin Nucleotide-binding domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
alpha/beta-Hydrolases beta-Roll 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Glycoside hydrolase/deacetylase UraD-Like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
(Trans)glycosidases Nucleotide-diphospho-sugar transferases 11
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
PP2C-like Protein kinase-like (PK-like) 11
beta-lactamase/transpeptidase-like Sporulation related repeat 11
PRTase-like EreA/ChaN-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Phage tail proteins gp5 N-terminal domain-like 11
CheC-like Surface presentation of antigens (SPOA) 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
TerB-like Chaperone J-domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
PK beta-barrel domain-like Riboflavin synthase domain-like 11
HAMP domain-like EAL domain-like 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
TGS-like ThrRS/AlaRS common domain 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
Adhesin YadA, collagen-binding domain Pili subunits 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
ALDH-like Thioesterase/thiol ester dehydrase-isomerase 11
alpha/beta-Hydrolases AhpD-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Nucleotide-binding domain Glutathione synthetase ATP-binding domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
DNA clamp DNA clamp 11
PIN domain-like DNA/RNA polymerases 11
PilZ domain-like PilZ domain-like 11
GAF domain-like Nucleotide cyclase 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
S-adenosyl-L-methionine-dependent methyltransferases PYP-like sensor domain (PAS domain) 11
Succinyl-CoA synthetase domains Citrate synthase 11
PheT/TilS domain Putative DNA-binding domain 11
Nucleic acid-binding proteins GAD domain-like 11
Pectin lyase-like Autotransporter 11
DNA topoisomerase I domain DNA breaking-rejoining enzymes 11
MoeA C-terminal domain-like Periplasmic binding protein-like II 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
Thiolase-like GroES-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors CheY-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Molybdenum cofactor-binding domain Bet v1-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Apolipoprotein A-I Apolipoprotein A-I 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Globin-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
NAD(P)-binding Rossmann-fold domains MurD-like peptide ligases, catalytic domain 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Ribonuclease H-like RuvA domain 2-like 11
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 11
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Ribonuclease H-like HRDC-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
ADC-like Cdc48 domain 2-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Protein kinase-like (PK-like) C-type lectin-like 11
RuvA domain 2-like P-loop containing nucleoside triphosphate hydrolases 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Fumarate reductase respiratory complex transmembrane subunits Nucleotide cyclase 11
4Fe-4S ferredoxins Respiratory nitrate reductase 1 gamma chain 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
PPK N-terminal domain-like PHP14-like 11
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 11
DNA-glycosylase Nudix 11
Dihydropteroate synthetase-like Methionine synthase domain 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
PspA lactotransferrin-binding region OmpA-like 11
Single hybrid motif FAD/NAD(P)-binding domain 11
Cobalamin (vitamin B12)-binding domain Radical SAM enzymes 11
S-adenosyl-L-methionine-dependent methyltransferases ACP-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Rudiment single hybrid motif Single hybrid motif 11
YebC-like PFL-like glycyl radical enzymes 11
TROVE domain-like vWA-like 11
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
Metallo-dependent phosphatases beta-Roll 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
YrdC/RibB RibA-like 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Urease, gamma-subunit Urease, beta-subunit 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
HRDC-like HRDC-like 11
C-terminal effector domain of the bipartite response regulators TPR-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
P-loop containing nucleoside triphosphate hydrolases Periplasmic binding protein-like II 11
DeoB insert domain-like Alkaline phosphatase-like 11
Methyl-accepting chemotaxis protein (MCP) signaling domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Nudix "Winged helix" DNA-binding domain 11
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Glycoside hydrolase/deacetylase Nucleotide-diphospho-sugar transferases 11

Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes · Domain combination pairs ]