SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Burkholderia cenocepacia HI2424

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

827 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 2162
Homeodomain-like Homeodomain-like 5311
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 4717
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 453
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 4218
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 346
CheY-like C-terminal effector domain of the bipartite response regulators 313
GroES-like NAD(P)-binding Rossmann-fold domains 313
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 273
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 263
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 241
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 244
Thioredoxin-like GST C-terminal domain-like 221
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 223
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 218
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 217
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 217
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 209
Actin-like ATPase domain Actin-like ATPase domain 206
"Winged helix" DNA-binding domain PLP-dependent transferases 191
Cytochrome c Cytochrome c 197
"Winged helix" DNA-binding domain GAF domain-like 192
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 195
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 186
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 186
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 186
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 186
Class I glutamine amidotransferase-like Homeodomain-like 173
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 175
P-loop containing nucleoside triphosphate hydrolases MOP-like 162
RmlC-like cupins Homeodomain-like 163
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 154
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 151
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 151
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 141
Thiolase-like Thiolase-like 131
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 134
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 129
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 113
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 114
Enolase N-terminal domain-like Enolase C-terminal domain-like 101
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 107
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 108
CheY-like Homeodomain-like 103
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 106
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 101
CheY-like P-loop containing nucleoside triphosphate hydrolases 103
cAMP-binding domain-like "Winged helix" DNA-binding domain 102
lambda repressor-like DNA-binding domains RmlC-like cupins 91
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 93
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 93
ISP domain Bet v1-like 92
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 95
P-loop containing nucleoside triphosphate hydrolases Translation proteins 95
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 82
Lysozyme-like beta-lactamase/transpeptidase-like 85
"Winged helix" DNA-binding domain Chorismate lyase-like 81
Homeodomain-like SIS domain 82
Phospholipase D/nuclease Phospholipase D/nuclease 86
Phage tail proteins Phage tail proteins 83
HlyD-like secretion proteins HlyD-like secretion proteins 83
Phage tail proteins gp5 N-terminal domain-like 83
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 84
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 73
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 73
Homodimeric domain of signal transducing histidine kinase CheY-like 75
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 73
Phage tail proteins Phage fibre proteins 62
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 62
(Trans)glycosidases Glycosyl hydrolase domain 65
Adhesin YadA, collagen-binding domain Adhesin YadA, collagen-binding domain 66
Adhesin YadA, collagen-binding domain Pili subunits 66
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 63
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 64
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 63
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 61
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 63
gp5 N-terminal domain-like Phage fibre proteins 62
PreATP-grasp domain Rudiment single hybrid motif 63
Regulatory protein AraC Homeodomain-like 62
EAL domain-like Nucleotide cyclase 64
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 51
Homeodomain-like Ribonuclease H-like 51
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 52
Alpha-L RNA-binding motif Pseudouridine synthase 53
PYP-like sensor domain (PAS domain) Nucleotide cyclase 54
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 54
ParB/Sulfiredoxin KorB DNA-binding domain-like 51
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 53
Acetyl-CoA synthetase-like ACP-like 55
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 52
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 54
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 52
CoA-dependent acyltransferases CoA-dependent acyltransferases 55
Triger factor/SurA peptide-binding domain-like FKBP-like 54
MetI-like MetI-like 41
(Trans)glycosidases E set domains 44
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
Translation proteins EF-G C-terminal domain-like 42
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 44
Pectin lyase-like Autotransporter 44
P-loop containing nucleoside triphosphate hydrolases C-terminal effector domain of the bipartite response regulators 42
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 43
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 43
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 42
PurM N-terminal domain-like PurM C-terminal domain-like 42
EF-G C-terminal domain-like EF-G C-terminal domain-like 42
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 42
Trypsin-like serine proteases PDZ domain-like 42
Single hybrid motif CoA-dependent acyltransferases 43
Calcium ATPase, transduction domain A HAD-like 43
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 41
PYP-like sensor domain (PAS domain) Homeodomain-like 43
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 42
PDZ domain-like PDZ domain-like 42
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 43
PLP-binding barrel Alanine racemase C-terminal domain-like 41
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 43
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
HAD-like Calcium ATPase, transmembrane domain M 43
ACP-like CoA-dependent acyltransferases 44
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 42
TPR-like TPR-like 44
MoeA N-terminal region -like MoeA C-terminal domain-like 42
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 42
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 42
PYP-like sensor domain (PAS domain) CheY-like 43
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 43
Aspartate receptor, ligand-binding domain Methyl-accepting chemotaxis protein (MCP) signaling domain 42
ACT-like ACT-like 43
Acetyl-CoA synthetase-like CoA-dependent acyltransferases 44
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 41
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 43
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
S-adenosyl-L-methionine-dependent methyltransferases ACP-like 33
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 31
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
CheY-like Methylesterase CheB, C-terminal domain 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 33
PYP-like sensor domain (PAS domain) EAL domain-like 32
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 32
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 33
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 32
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 32
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 32
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 32
Nucleotide-diphospho-sugar transferases RmlC-like cupins 32
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 33
LeuD/IlvD-like Aconitase iron-sulfur domain 32
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 33
alpha/beta-Hydrolases alpha/beta-Hydrolases 32
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 32
Pectin lyase-like Pectin lyase-like 33
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 33
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 32
GroEL equatorial domain-like GroEL-intermediate domain like 31
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 32
HD-domain/PDEase-like Nucleotidyltransferase 33
RuvA domain 2-like Nucleic acid-binding proteins 33
GroEL-intermediate domain like GroEL apical domain-like 31
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 32
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 31
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 32
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 33
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 32
GAF domain-like Homeodomain-like 32
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
ACP-like ACP-like 33
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 32
CBS-domain pair FAD-binding/transporter-associated domain-like 31
Protease propeptides/inhibitors Subtilisin-like 32
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 33
Ribosomal protein S5 domain 2-like EF-G C-terminal domain-like 32
GroEL equatorial domain-like GroEL apical domain-like 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 32
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 32
EAL domain-like Sensory domain-like 31
MOP-like MOP-like 22
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 22
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 22
6-phosphogluconate dehydrogenase C-terminal domain-like ClpP/crotonase 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 22
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 21
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
(Trans)glycosidases Class I glutamine amidotransferase-like 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 22
DsbC/DsbG N-terminal domain-like Thioredoxin-like 22
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 21
Clc chloride channel CBS-domain pair 21
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 22
Nucleotidyltransferase TGS-like 22
HMA, heavy metal-associated domain HAD-like 22
Nucleotidyltransferase ACT-like 22
Aspartate/glutamate racemase Aspartate/glutamate racemase 21
Translation proteins Ribosomal protein S5 domain 2-like 21
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 22
Glutathione synthetase ATP-binding domain-like Single hybrid motif 22
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 22
ACT-like Formyltransferase 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
alpha-D-mannose-specific plant lectins alpha-D-mannose-specific plant lectins 22
Folate-binding domain Aminomethyltransferase beta-barrel domain 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
Aldolase post-HMGL domain-like 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
FMN-linked oxidoreductases Nucleotide-binding domain 21
E set domains Glycosyl hydrolase domain 22
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 21
MalF N-terminal region-like MetI-like 21
Class I glutamine amidotransferase-like Glycosyl hydrolase domain 21
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 21
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
Galactose-binding domain-like Galactose-binding domain-like 21
Formyltransferase FMT C-terminal domain-like 21
Sigma2 domain of RNA polymerase sigma factors NTF2-like 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 22
Heme-dependent peroxidases Heme-dependent peroxidases 21
Nucleotide-binding domain FAD/NAD(P)-binding domain 21
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 21
S-adenosyl-L-methionine-dependent methyltransferases UDP-Glycosyltransferase/glycogen phosphorylase 22
alpha-helical ferredoxin Nucleotide-binding domain 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 22
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 22
CheY-like PLP-dependent transferases 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 22
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 21
Nqo1 middle domain-like Nqo1C-terminal domain-like 22
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 21
HAMP domain-like PYP-like sensor domain (PAS domain) 22
Single hybrid motif FAD/NAD(P)-binding domain 21
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 22
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 22
TATA-box binding protein-like DNA-glycosylase 22
P-loop containing nucleoside triphosphate hydrolases ACT-like 21
Rudiment single hybrid motif Single hybrid motif 22
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 21
GAF domain-like Nucleotide cyclase 22
PRC-barrel domain PRC-barrel domain 22
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 22
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 22
HD-domain/PDEase-like TGS-like 22
CoA-dependent acyltransferases S-adenosyl-L-methionine-dependent methyltransferases 22
Histidine-containing phosphotransfer domain, HPT domain CheW-like 22
2Fe-2S ferredoxin-like alpha-helical ferredoxin 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
Ribonuclease H-like DNA/RNA polymerases 22
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 21
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 22
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 22
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 22
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 21
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 21
YrdC/RibB RibA-like 21
Riboflavin synthase domain-like Riboflavin synthase domain-like 21
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 21
ACP-like NAD(P)-binding Rossmann-fold domains 22
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
Acetyl-CoA synthetase-like S-adenosyl-L-methionine-dependent methyltransferases 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
PreATP-grasp domain Single hybrid motif 22
HD-domain/PDEase-like ACT-like 22
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 21
Sigma3 and sigma4 domains of RNA polymerase sigma factors NTF2-like 21
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
L30e-like alpha/beta knot 21
MFS general substrate transporter MFS general substrate transporter 21
alpha/beta-Hydrolases S-adenosyl-L-methionine-dependent methyltransferases 22
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
CheY-like Ornithine decarboxylase C-terminal domain 22
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 22
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 21
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
PDZ domain-like ClpP/crotonase 21
NAD(P)-binding Rossmann-fold domains ClpP/crotonase 22
Cyclophilin-like PH0987 N-terminal domain-like 22
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 21
Cupredoxins Cupredoxins 22
Translation proteins ThrRS/AlaRS common domain 22
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 22
Positive stranded ssRNA viruses Pectin lyase-like 11
Ribonuclease H-like GIY-YIG endonuclease 11
CheY-binding domain of CheA CheW-like 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Ribbon-helix-helix N-terminal domain of bifunctional PutA protein 11
Nucleic acid-binding proteins PheT/TilS domain 11
Thiolase-like ACP-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
CheC-like Surface presentation of antigens (SPOA) 11
FMN-binding split barrel 2Fe-2S ferredoxin-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Galactose mutarotase-like (Trans)glycosidases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
ABC transporter involved in vitamin B12 uptake, BtuC ABC transporter involved in vitamin B12 uptake, BtuC 11
Molybdenum cofactor-binding domain Cytochrome c 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
FAD-linked oxidoreductase ALDH-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Tex N-terminal region-like Ribonuclease H-like 11
Rudiment single hybrid motif PH0987 N-terminal domain-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
NAD-binding domain of HMG-CoA reductase Substrate-binding domain of HMG-CoA reductase 11
Ribbon-helix-helix FAD-linked oxidoreductase 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
ABC transporter transmembrane region CheY-like 11
Nucleotide-binding domain Nucleotide-binding domain 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
P-loop containing nucleoside triphosphate hydrolases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
(Phosphotyrosine protein) phosphatases II FAD/NAD(P)-binding domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
CbiG N-terminal domain-like CobE/GbiG C-terminal domain-like 11
RuvA domain 2-like BRCT domain 11
Acetyl-CoA synthetase-like NAD(P)-binding Rossmann-fold domains 11
Ribosomal protein L6 Ribosomal protein L6 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
DAK1/DegV-like DhaL-like 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
Positive stranded ssRNA viruses Autotransporter 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
CbiG N-terminal domain-like Tetrapyrrole methylase 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
Ribonuclease H-like RuvA domain 2-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
MFS general substrate transporter S-adenosyl-L-methionine-dependent methyltransferases 11
Lysozyme-like LysM domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
PreATP-grasp domain PreATP-grasp domain 11
L domain-like Protein kinase-like (PK-like) 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Duplicated hybrid motif Phosphohistidine domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
RuvA domain 2-like JAB1/MPN domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
FMN-binding split barrel Riboflavin synthase domain-like 11
DNA-glycosylase Nudix 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
cAMP-binding domain-like FAD/NAD(P)-binding domain 11
Globin-like Riboflavin synthase domain-like 11
Chorismate mutase II Periplasmic binding protein-like II 11
Acetyl-CoA synthetase-like alpha/beta-Hydrolases 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
PUA domain-like alpha/beta knot 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
HPr-like Phosphohistidine domain 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Periplasmic binding protein-like II Cytochrome c 11
MesJ substrate recognition domain-like PheT/TilS domain 11
alpha/beta-Hydrolases NTF2-like 11
Carbamate kinase-like ACT-like 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
Resolvase-like Homeodomain-like 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
GAF domain-like GAF domain-like 11
HprK N-terminal domain-like PEP carboxykinase-like 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
CobE/GbiG C-terminal domain-like Tetrapyrrole methylase 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
CheY-like Nucleotide cyclase 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
RuvA domain 2-like RuvA domain 2-like 11
Cupredoxins Cytochrome c 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Thiolase-like GroES-like 11
PreATP-grasp domain Cyclophilin-like 11
GroES-like GroES-like 11
Nucleotide-diphospho-sugar transferases PilZ domain-like 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
Duplicated hybrid motif HPr-like 11
HAMP domain-like Nucleotide cyclase 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
lambda repressor-like DNA-binding domains CheY-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Thiolase-like FabD/lysophospholipase-like 11
Prim-pol domain P-loop containing nucleoside triphosphate hydrolases 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Ferredoxin reductase-like, C-terminal NADP-linked domain 11
PurS-like PurM N-terminal domain-like 11
Tex N-terminal region-like RuvA domain 2-like 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
GAF domain-like Homodimeric domain of signal transducing histidine kinase 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Galactose mutarotase-like Glycosyl hydrolase domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Translation proteins PRC-barrel domain 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
CBS-domain pair Nucleotide cyclase 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
ABC transporter transmembrane region ABC transporter transmembrane region 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Class II aaRS and biotin synthetases GAD domain-like 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Flavoproteins 11
Periplasmic binding protein-like I Homeodomain-like 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Nucleotidylyl transferase tRNA-binding arm 11
Trigger factor ribosome-binding domain FKBP-like 11
cAMP-binding domain-like FliG 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Chorismate mutase II ACT-like 11
TGS-like ACT-like 11
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 11
Cytochrome c oxidase subunit II-like, transmembrane region OmpA-like 11
Cytochrome c OmpA-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase GroES-like 11
Nucleotidylyl transferase Nudix 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
DinB/YfiT-like putative metalloenzymes C-type lectin-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
Nucleotide-diphospho-sugar transferases UDP-Glycosyltransferase/glycogen phosphorylase 11
Tropomyosin TPR-like 11
Thioredoxin-like TPR-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
beta-lactamase/transpeptidase-like beta-lactamase/transpeptidase-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
YajQ-like YajQ-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Glutathione synthetase ATP-binding domain-like Cyclophilin-like 11
TGS-like Class II aaRS and biotin synthetases 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Carbohydrate-binding domain (Trans)glycosidases 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
MoeA N-terminal region -like SMI1/KNR4-like 11
Nucleotide cyclase P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Oxidoreductase molybdopterin-binding domain E set domains 11
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
YegP-like YegP-like 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
Metalloproteases ("zincins"), catalytic domain PDZ domain-like 11
"Winged helix" DNA-binding domain MOP-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Cupredoxins OmpA-like 11
Flavoproteins Riboflavin synthase domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases TPR-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
CheY-like Purine and uridine phosphorylases 11
Nucleic acid-binding proteins BRCT domain 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
CheY-binding domain of CheA Homodimeric domain of signal transducing histidine kinase 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
NagB/RpiA/CoA transferase-like 4Fe-4S ferredoxins 11
GAF domain-like EAL domain-like 11
Sec63 N-terminal domain-like PHP domain-like 11
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Ribbon-helix-helix ALDH-like 11
Actin-like ATPase domain Homeodomain-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Single hybrid motif alpha/beta-Hydrolases 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Sensory domain-like HAMP domain-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Cyclophilin-like Cyclophilin-like 11
ADC-like Flavoproteins 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
Periplasmic binding protein-like II NosL/MerB-like 11
PapD-like Periplasmic chaperone C-domain 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Periplasmic binding protein-like II ACT-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase S-adenosyl-L-methionine-dependent methyltransferases 11
MoeA C-terminal domain-like SMI1/KNR4-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Chaperone J-domain HSP40/DnaJ peptide-binding domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
(Trans)glycosidases Carbohydrate binding domain 11
GIY-YIG endonuclease RuvA domain 2-like 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Cytochrome c oxidase subunit I-like Cytochrome c oxidase subunit III-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) TATA-box binding protein-like 11
MOSC N-terminal domain-like PK beta-barrel domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
HD-domain/PDEase-like C-terminal effector domain of the bipartite response regulators 11
Actin-like ATPase domain HD-domain/PDEase-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
CheY-binding domain of CheA ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
EAL domain-like CBS-domain pair 11
Dihydropteroate synthetase-like Methionine synthase domain 11
PPK N-terminal domain-like PHP14-like 11
S-adenosyl-L-methionine-dependent methyltransferases GroES-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
Acetyl-CoA synthetase-like Acetyl-CoA synthetase-like 11
ABC transporter transmembrane region ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
ADC-like Riboflavin synthase domain-like 11
CoA-transferase family III (CaiB/BaiF) CoA-transferase family III (CaiB/BaiF) 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Nucleic acid-binding proteins GAD domain-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
PHP14-like Phospholipase D/nuclease 11
PheT/TilS domain Putative DNA-binding domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Glucose permease domain IIB Glucose permease domain IIB 11
Carbohydrate-binding domain beta-N-acetylhexosaminidase-like domain 11
PurS-like Class I glutamine amidotransferase-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Pseudouridine synthase PUA domain-like 11
MetI-like P-loop containing nucleoside triphosphate hydrolases 11
Dimeric alpha+beta barrel Dimeric alpha+beta barrel 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
ACP-like alpha/beta-Hydrolases 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 11
Voltage-gated potassium channels E set domains 11
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
"Winged helix" DNA-binding domain Phospholipase D/nuclease 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Chondroitin AC/alginate lyase Concanavalin A-like lectins/glucanases 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) DNA-glycosylase 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Phosphoenolpyruvate/pyruvate domain Nucleotide-diphospho-sugar transferases 11
Carbohydrate-binding domain E set domains 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Actin-like ATPase domain SIS domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
CarD-like TRCF domain-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Nucleotide cyclase TPR-like 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Protein prenylyltransferase UDP-Glycosyltransferase/glycogen phosphorylase 11
FKBP-like FKBP-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Histidine-containing phosphotransfer domain, HPT domain CheY-binding domain of CheA 11
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 11
TGS-like Class II aaRS ABD-related 11
S-adenosyl-L-methionine-dependent methyltransferases Nucleotide-diphospho-sugar transferases 11
Translation proteins Translation proteins 11
FabD/lysophospholipase-like GroES-like 11
Carbamate kinase-like PUA domain-like 11
CoA-dependent acyltransferases alpha/beta-Hydrolases 11
Galactose-binding domain-like (Trans)glycosidases 11
Protein kinase-like (PK-like) Nucleotide cyclase 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Tricorn protease N-terminal domain Galactose-binding domain-like 11
PIN domain-like DNA/RNA polymerases 11
"Winged helix" DNA-binding domain Nucleotidyltransferase 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
TGS-like ThrRS/AlaRS common domain 11
Acetyl-CoA synthetase-like Thioesterase/thiol ester dehydrase-isomerase 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Protein prenylyltransferase TPR-like 11
GroES-like ACP-like 11
Sensory domain-like Nucleotide cyclase 11
Sm-like ribonucleoproteins cAMP-binding domain-like 11
FabD/lysophospholipase-like S-adenosyl-L-methionine-dependent methyltransferases 11
ClpP/crotonase ClpP/crotonase 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
DNA polymerase beta, N-terminal domain-like RuvA domain 2-like 11
Heme-dependent catalase-like Class I glutamine amidotransferase-like 11
Nucleotidyltransferase PHP domain-like 11
Macro domain-like Zn-dependent exopeptidases 11
Adenine nucleotide alpha hydrolases-like GAF domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
alpha/beta-Hydrolases NAD(P)-binding Rossmann-fold domains 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Riboflavin synthase domain-like 11
FMN-binding split barrel Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Rudiment single hybrid motif Cyclophilin-like 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
P-loop containing nucleoside triphosphate hydrolases TPR-like 11
Thioredoxin-like Thioredoxin-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Galactose mutarotase-like Galactose mutarotase-like 11
CheW-like CheY-like 11
Phase 1 flagellin Phase 1 flagellin 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Trypsin-like serine proteases TPR-like 11
DNA topoisomerase I domain DNA breaking-rejoining enzymes 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Homeodomain-like TATA-box binding protein-like 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain "Winged helix" DNA-binding domain 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
Single hybrid motif Single hybrid motif 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
FAD/NAD(P)-binding domain Folate-binding domain 11
PrpR receptor domain-like Homeodomain-like 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
YjeF N-terminal domain-like Ribokinase-like 11
Metallo-hydrolase/oxidoreductase Rhodanese/Cell cycle control phosphatase 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Rhodanese/Cell cycle control phosphatase P-loop containing nucleoside triphosphate hydrolases 11
Histidine-containing phosphotransfer domain, HPT domain CheY-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Putative DNA-binding domain Translation proteins 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Carbohydrate binding domain Carbohydrate binding domain 11
Zinc beta-ribbon DNA primase core 11
HPr-like Phosphoenolpyruvate/pyruvate domain 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
PH0987 N-terminal domain-like Single hybrid motif 11
Putative DNA-binding domain Citrate synthase 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
(Trans)glycosidases (Trans)glycosidases 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 11
CheY-like HD-domain/PDEase-like 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
PurS-like FGAM synthase PurL, linker domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
ISP domain FAD/NAD(P)-binding domain 11
PLP-dependent transferases PLP-dependent transferases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Galactose mutarotase-like Six-hairpin glycosidases 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
DNA polymerase beta, N-terminal domain-like PHP domain-like 11
Thiolase-like S-adenosyl-L-methionine-dependent methyltransferases 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
GntR ligand-binding domain-like GntR ligand-binding domain-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
ADC-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
FliG FliG 11
Duplicated hybrid motif Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Thiolase-like NAD(P)-binding Rossmann-fold domains 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Bacterial muramidases Lysozyme-like 11
ISP domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
PurS-like PurM C-terminal domain-like 11
Protein kinase-like (PK-like) TPR-like 11
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 11
DNA clamp DNA clamp 11
Glycosyl hydrolase domain Protein kinase-like (PK-like) 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
Pili subunits GspK insert domain-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
DNA polymerase beta, N-terminal domain-like Sec63 N-terminal domain-like 11
PIN domain-like Ribonuclease H-like 11
FMN-linked oxidoreductases 4Fe-4S ferredoxins 11
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 11
Cyclophilin-like Single hybrid motif 11
Glutathione synthetase ATP-binding domain-like PH0987 N-terminal domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Hsp33 domain HSP33 redox switch-like 11
UROD/MetE-like UROD/MetE-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Sec63 N-terminal domain-like Nucleotidyltransferase 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
PreATP-grasp domain PH0987 N-terminal domain-like 11
2Fe-2S ferredoxin-like ADC-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 11
beta-N-acetylhexosaminidase-like domain E set domains 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Homeodomain-like Probable bacterial effector-binding domain 11
Homeodomain-like DNA-glycosylase 11
Purple acid phosphatase, N-terminal domain Metallo-dependent phosphatases 11
beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
Duplicated hybrid motif Phosphoenolpyruvate/pyruvate domain 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
beta-N-acetylhexosaminidase-like domain (Trans)glycosidases 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Surface presentation of antigens (SPOA) Surface presentation of antigens (SPOA) 11
Translation proteins "Winged helix" DNA-binding domain 11
FAD/NAD(P)-binding domain alpha/beta-Hydrolases 11
Mechanosensitive channel protein MscS (YggB), C-terminal domain cAMP-binding domain-like 11
PrpR receptor domain-like PYP-like sensor domain (PAS domain) 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
Molybdenum cofactor biosynthesis proteins SMI1/KNR4-like 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
ClpP/crotonase NfeD domain-like 11
PrpR receptor domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
RNase III domain-like dsRNA-binding domain-like 11
FabD/lysophospholipase-like ACP-like 11
4Fe-4S ferredoxins ADC-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
PK beta-barrel domain-like PK C-terminal domain-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Origin of replication-binding domain, RBD-like P-loop containing nucleoside triphosphate hydrolases 11
GAF domain-like PYP-like sensor domain (PAS domain) 11

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