SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Pseudomonas fluorescens SBW25

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

793 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 1212
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 6930
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 4113
Homeodomain-like Homeodomain-like 368
CheY-like C-terminal effector domain of the bipartite response regulators 311
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 294
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 283
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 263
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 2420
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 232
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 224
Homodimeric domain of signal transducing histidine kinase CheY-like 2117
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 2013
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 2010
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 1912
Thioredoxin-like GST C-terminal domain-like 192
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 195
GroES-like NAD(P)-binding Rossmann-fold domains 192
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 184
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 174
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 175
Nucleotide cyclase EAL domain-like 1711
Class I glutamine amidotransferase-like Homeodomain-like 163
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 153
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 153
P-loop containing nucleoside triphosphate hydrolases MOP-like 151
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 151
Actin-like ATPase domain Actin-like ATPase domain 154
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 155
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 153
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 155
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 1511
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 153
Thiolase-like Thiolase-like 151
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 153
PYP-like sensor domain (PAS domain) Nucleotide cyclase 1410
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 146
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 134
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 134
Acetyl-CoA synthetase-like ACP-like 1212
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 123
CoA-dependent acyltransferases Acetyl-CoA synthetase-like 1111
CoA-dependent acyltransferases ACP-like 1111
CoA-dependent acyltransferases CoA-dependent acyltransferases 1111
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 112
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 116
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 112
"Winged helix" DNA-binding domain GAF domain-like 101
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 102
"Winged helix" DNA-binding domain PLP-dependent transferases 101
Cytochrome c Cytochrome c 105
PYP-like sensor domain (PAS domain) CheY-like 97
RmlC-like cupins Homeodomain-like 92
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 91
CheY-like P-loop containing nucleoside triphosphate hydrolases 92
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 93
PYP-like sensor domain (PAS domain) EAL domain-like 97
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 82
Acetyl-CoA synthetase-like Acetyl-CoA synthetase-like 88
CheY-like Homeodomain-like 81
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 86
"Winged helix" DNA-binding domain Chorismate lyase-like 81
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 83
PreATP-grasp domain Rudiment single hybrid motif 82
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 86
ACP-like ACP-like 88
GAF domain-like Homodimeric domain of signal transducing histidine kinase 75
Calcium ATPase, transduction domain A HAD-like 75
Enolase N-terminal domain-like Enolase C-terminal domain-like 71
lambda repressor-like DNA-binding domains RmlC-like cupins 71
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 74
HAD-like Calcium ATPase, transmembrane domain M 75
CheY-like Histidine-containing phosphotransfer domain, HPT domain 76
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 75
Folate-binding domain Aminomethyltransferase beta-barrel domain 73
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 62
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 62
Phospholipase D/nuclease Phospholipase D/nuclease 64
CheW-like CheY-like 64
P-loop containing nucleoside triphosphate hydrolases Translation proteins 66
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 66
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 64
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 61
PYP-like sensor domain (PAS domain) Homeodomain-like 66
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 61
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Regulatory protein AraC Homeodomain-like 62
ACT-like ACT-like 63
Lysozyme-like beta-lactamase/transpeptidase-like 53
CheY-like CheY-like 55
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 55
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 55
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 54
PLP-binding barrel Alanine racemase C-terminal domain-like 52
GAF domain-like PYP-like sensor domain (PAS domain) 55
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 54
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 51
MetI-like MetI-like 52
Alpha-L RNA-binding motif Pseudouridine synthase 52
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 54
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 51
cAMP-binding domain-like "Winged helix" DNA-binding domain 41
lambda repressor-like DNA-binding domains LexA/Signal peptidase 41
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 43
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 42
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 43
PH0987 N-terminal domain-like Cyclophilin-like 41
ISP domain Bet v1-like 42
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 43
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 41
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 41
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 43
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 43
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 43
CheY-like Nucleotide cyclase 44
(Trans)glycosidases Glycosyl hydrolase domain 44
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 43
PapD-like Periplasmic chaperone C-domain 42
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 42
CBS-domain pair FAD-binding/transporter-associated domain-like 41
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 42
Histidine-containing phosphotransfer domain, HPT domain CheW-like 43
RuvA domain 2-like Nucleic acid-binding proteins 44
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 41
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 42
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 44
Periplasmic binding protein-like II PYP-like sensor domain (PAS domain) 43
Homeodomain-like Ribonuclease H-like 41
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 43
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 43
ACT-like Formyltransferase 41
CheY-like EAL domain-like 43
Homeodomain-like SIS domain 41
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 42
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 32
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 32
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 33
Triger factor/SurA peptide-binding domain-like FKBP-like 33
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 31
gp5 N-terminal domain-like Phage fibre proteins 31
CheY-like Methylesterase CheB, C-terminal domain 31
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 31
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 32
HAMP domain-like CheY-like 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 32
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 31
ACP-like alpha/beta-Hydrolases 33
TPR-like TPR-like 33
Nucleotide-diphospho-sugar transferases RmlC-like cupins 31
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 32
Translation proteins EF-G C-terminal domain-like 33
HPr-like Phosphoenolpyruvate/pyruvate domain 32
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
PurM N-terminal domain-like PurM C-terminal domain-like 32
Translation proteins ThrRS/AlaRS common domain 32
GAF domain-like Homeodomain-like 33
Single hybrid motif CoA-dependent acyltransferases 32
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 32
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 32
Acetyl-CoA synthetase-like alpha/beta-Hydrolases 33
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 32
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 32
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 31
HMA, heavy metal-associated domain HAD-like 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
P-loop containing nucleoside triphosphate hydrolases C-terminal effector domain of the bipartite response regulators 32
HD-domain/PDEase-like Nucleotidyltransferase 32
Metalloproteases ("zincins"), catalytic domain beta-Roll 32
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 31
Nucleotidyltransferase ACT-like 32
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
CoA-dependent acyltransferases alpha/beta-Hydrolases 33
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
HD-domain/PDEase-like ACT-like 32
HlyD-like secretion proteins HlyD-like secretion proteins 31
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Phage tail proteins gp5 N-terminal domain-like 31
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 31
Phage tail proteins Phage tail proteins 31
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
Phage tail proteins Phage fibre proteins 31
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 31
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 32
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 33
E set domains (Trans)glycosidases 33
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 33
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 31
Periplasmic binding protein-like II Periplasmic binding protein-like II 32
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 32
Aconitase iron-sulfur domain LeuD/IlvD-like 33
HPr-like Phosphohistidine domain 32
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
ACT-like P-loop containing nucleoside triphosphate hydrolases 32
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
PDZ domain-like PDZ domain-like 22
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 21
E set domains Glycosyl hydrolase domain 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
"Winged helix" DNA-binding domain LexA/Signal peptidase 21
Duplicated hybrid motif Phosphoenolpyruvate/pyruvate domain 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Periplasmic binding protein-like II Lysozyme-like 22
Pili subunits GspK insert domain-like 21
ParB/Sulfiredoxin KorB DNA-binding domain-like 21
P-loop containing nucleoside triphosphate hydrolases MetI-like 22
PUA domain-like Ribosomal protein S5 domain 2-like 22
Duplicated hybrid motif Phosphohistidine domain 21
NAD(P)-binding Rossmann-fold domains ACT-like 22
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
PreATP-grasp domain Single hybrid motif 21
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
ClpP/crotonase ClpP/crotonase 21
FAD/NAD(P)-binding domain HI0933 insert domain-like 21
Duplicated hybrid motif Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 21
alpha-helical ferredoxin Nucleotide-binding domain 21
FAD/NAD(P)-binding domain Folate-binding domain 21
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 21
HAMP domain-like PYP-like sensor domain (PAS domain) 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Periplasmic binding protein-like II CheY-like 21
Formyltransferase FMT C-terminal domain-like 22
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 22
Homodimeric domain of signal transducing histidine kinase CheW-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 21
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Nucleotidyltransferase TGS-like 21
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 21
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 21
YrdC/RibB RibA-like 21
HD-domain/PDEase-like TGS-like 21
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 21
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
Periplasmic binding protein-like II Histidine-containing phosphotransfer domain, HPT domain 21
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 22
Galactose mutarotase-like E set domains 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
PK beta-barrel domain-like PK C-terminal domain-like 21
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 22
HAMP domain-like EAL domain-like 21
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 21
PDZ domain-like ClpP/crotonase 21
Trypsin-like serine proteases PDZ domain-like 22
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 21
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 21
Rudiment single hybrid motif Single hybrid motif 21
Flavoproteins Riboflavin synthase domain-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 21
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 22
Pili subunits Pili subunits 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
GAF domain-like CheY-like 22
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 21
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 22
Pili subunits RuvA domain 2-like 21
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 21
CheY-like HD-domain/PDEase-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Ribonuclease H-like DNA/RNA polymerases 22
HAMP domain-like Nucleotide cyclase 21
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 21
DsbC/DsbG N-terminal domain-like Thioredoxin-like 21
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 22
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 22
GspK insert domain-like RuvA domain 2-like 21
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 22
RuvA domain 2-like RuvA domain 2-like 22
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 21
Aspartate/glutamate racemase Aspartate/glutamate racemase 21
Duplicated hybrid motif HPr-like 21
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 21
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 21
Glutathione synthetase ATP-binding domain-like Single hybrid motif 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 21
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
Aldolase post-HMGL domain-like 22
TGS-like ACT-like 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 21
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 22
ADC-like Riboflavin synthase domain-like 11
alpha/beta-Hydrolases S-adenosyl-L-methionine-dependent methyltransferases 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Riboflavin synthase domain-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Nucleic acid-binding proteins BRCT domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
PP2C-like Protein kinase-like (PK-like) 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
PIN domain-like DNA/RNA polymerases 11
Single hybrid motif Single hybrid motif 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
ACT-like PYP-like sensor domain (PAS domain) 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Acetyl-CoA synthetase-like Thioesterase/thiol ester dehydrase-isomerase 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Actin-like ATPase domain HD-domain/PDEase-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
FAD/NAD(P)-binding domain alpha/beta-Hydrolases 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
MoaD/ThiS Activating enzymes of the ubiquitin-like proteins 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
Chorismate mutase II Periplasmic binding protein-like II 11
Globin-like Riboflavin synthase domain-like 11
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 11
Acyl-CoA dehydrogenase C-terminal domain-like Acyl-CoA dehydrogenase C-terminal domain-like 11
ADC-like Flavoproteins 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Putative DNA-binding domain Translation proteins 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors TPR-like 11
Rhodanese/Cell cycle control phosphatase PLP-dependent transferases 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
CoA-dependent acyltransferases Clavaminate synthase-like 11
2Fe-2S ferredoxin-like ADC-like 11
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
CO dehydrogenase molybdoprotein N-domain-like Cytochrome c 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
TATA-box binding protein-like DNA-glycosylase 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Glycosyl hydrolase domain Protein kinase-like (PK-like) 11
PUA domain-like alpha/beta knot 11
Cloacin translocation domain Ribonuclease domain of colicin E3 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
FMN-linked oxidoreductases 4Fe-4S ferredoxins 11
JAB1/MPN domain Cysteine proteinases 11
FAD-linked oxidoreductase ALDH-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
(Trans)glycosidases Nucleotide-diphospho-sugar transferases 11
Receptor-binding domain of short tail fibre protein gp12 Receptor-binding domain of short tail fibre protein gp12 11
Nucleic acid-binding proteins GAD domain-like 11
alpha/beta-Hydrolases alpha/beta-Hydrolases 11
Ribosomal protein L6 Ribosomal protein L6 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Zinc beta-ribbon Zinc beta-ribbon 11
DNA clamp DNA clamp 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Hsp33 domain HSP33 redox switch-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Ribbon-helix-helix ALDH-like 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
Periplasmic binding protein-like II OmpA-like 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Chorismate mutase II ACT-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Aldolase Single hybrid motif 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
PurS-like PurM N-terminal domain-like 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
FMN-binding split barrel UbiD C-terminal domain-like 11
ACP-like NAD(P)-binding Rossmann-fold domains 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Bacterial muramidases Lysozyme-like 11
PheT/TilS domain Putative DNA-binding domain 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
cAMP-binding domain-like CBS-domain pair 11
PTS system IIB component-like PTS system IIB component-like 11
PreATP-grasp domain PreATP-grasp domain 11
PIN domain-like Ribonuclease H-like 11
YbaK/ProRS associated domain HD-domain/PDEase-like 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
ACT-like HAD-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Ligand-binding domain in the NO signalling and Golgi transport P-loop containing nucleoside triphosphate hydrolases 11
6-phosphogluconate dehydrogenase C-terminal domain-like EPT/RTPC-like 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Sigma2 domain of RNA polymerase sigma factors TPR-like 11
TPR-like P-loop containing nucleoside triphosphate hydrolases 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
THUMP domain-like Adenine nucleotide alpha hydrolases-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
PurS-like PurM C-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
RmlC-like cupins RmlC-like cupins 11
Radical SAM enzymes RuvA domain 2-like 11
TTHA1013/TTHA0281-like Ribbon-helix-helix 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Ribokinase-like Nucleotidylyl transferase 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
4Fe-4S ferredoxins ADC-like 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain TPR-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Nitrous oxide reductase, N-terminal domain Nitrous oxide reductase, N-terminal domain 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
TSP type-3 repeat OmpA-like 11
PurS-like Class I glutamine amidotransferase-like 11
L domain-like L domain-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Oxidoreductase molybdopterin-binding domain E set domains 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Lysozyme-like PGBD-like 11
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase MetI-like 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
GroEL-intermediate domain like GroEL apical domain-like 11
HRDC-like HRDC-like 11
Inosine monophosphate dehydrogenase (IMPDH) Nitrite and sulphite reductase 4Fe-4S domain-like 11
(Trans)glycosidases Anthrax protective antigen 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Bacterial polysaccharide co-polymerase-like Bacterial polysaccharide co-polymerase-like 11
Glucose permease domain IIB Glucose permease domain IIB 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Nudix Nudix 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Protein kinase-like (PK-like) Protein kinase-like (PK-like) 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
NTF2-like Homeodomain-like 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
E set domains E set domains 11
ACP-like Clavaminate synthase-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
MgtE N-terminal domain-like CBS-domain pair 11
Acetyl-CoA synthetase-like Clavaminate synthase-like 11
Thioredoxin-like Thioredoxin-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Cupredoxins Cupredoxins 11
UROD/MetE-like UROD/MetE-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Phoshotransferase/anion transport protein Phoshotransferase/anion transport protein 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Mechanosensitive channel protein MscS (YggB), C-terminal domain cAMP-binding domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
vWA-like TPR-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
PGBD-like L,D-transpeptidase catalytic domain-like 11
FMN-linked oxidoreductases Nucleotide-binding domain 11
GroES-like GroES-like 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Phoshotransferase/anion transport protein Phosphohistidine domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Barwin-like endoglucanases Sporulation related repeat 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
RNase III domain-like dsRNA-binding domain-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
S-adenosyl-L-methionine-dependent methyltransferases FAD/NAD(P)-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
EAL domain-like Sensory domain-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Caspase-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
TGS-like Class II aaRS and biotin synthetases 11
Translation proteins Translation proteins 11
ARM repeat TPR-like 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
NAD(P)-binding Rossmann-fold domains EPT/RTPC-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Phoshotransferase/anion transport protein HPr-like 11
FMN-binding split barrel "Winged helix" DNA-binding domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Translation proteins PRC-barrel domain 11
Phase 1 flagellin Phase 1 flagellin 11
NTF2-like Sec-C motif 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
Adenine nucleotide alpha hydrolases-like Rhodanese/Cell cycle control phosphatase 11
MOSC N-terminal domain-like PK beta-barrel domain-like 11
CheC-like Surface presentation of antigens (SPOA) 11
Galactose mutarotase-like Galactose-binding domain-like 11
OMPA-like OmpA-like 11
Ribbon-helix-helix FAD-linked oxidoreductase 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
RuvA domain 2-like BRCT domain 11
Formyltransferase NAD(P)-binding Rossmann-fold domains 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Flavoproteins 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes CBS-domain pair 11
FMT C-terminal domain-like NAD(P)-binding Rossmann-fold domains 11
Class II aaRS and biotin synthetases GAD domain-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
TrkA C-terminal domain-like FAD-binding/transporter-associated domain-like 11
RuvA domain 2-like JAB1/MPN domain 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Thermostable phytase (3-phytase) Thermostable phytase (3-phytase) 11
Periplasmic binding protein-like I Homeodomain-like 11
Protein kinase-like (PK-like) PLP-dependent transferases 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
GAF domain-like Phosphohistidine domain 11
Nucleotidylyl transferase tRNA-binding arm 11
NAD(P)-binding Rossmann-fold domains RmlC-like cupins 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
Galactose mutarotase-like Starch-binding domain-like 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Ligand-binding domain in the NO signalling and Golgi transport Homeodomain-like 11
Nucleic acid-binding proteins PheT/TilS domain 11
JAB1/MPN domain MoaD/ThiS 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
Pectin lyase-like Hedgehog/intein (Hint) domain 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Carbamate kinase-like PUA domain-like 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Nucleotide-diphospho-sugar transferases PilZ domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Thioredoxin-like TPR-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
TPR-like C-terminal effector domain of the bipartite response regulators 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
GAF domain-like Nucleotide cyclase 11
HCP-like HCP-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
CbiG N-terminal domain-like Tetrapyrrole methylase 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
ACT-like Homeodomain-like 11
Resolvase-like Homeodomain-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Zinc beta-ribbon DNA primase core 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
post-HMGL domain-like Single hybrid motif 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Sporulation related repeat 11
FKBP-like FKBP-like 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Ribbon-helix-helix N-terminal domain of bifunctional PutA protein 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Cupredoxins Cytochrome c 11
MFS general substrate transporter Proline/betaine transporter ProP, C-terminal cytoplasmic domain 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 11
CBS-domain pair MgtE membrane domain-like 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Phoshotransferase/anion transport protein Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
DNA primase core DNA primase DnaG, C-terminal domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
GroEL equatorial domain-like GroEL apical domain-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 11
Nqo5-like HydB/Nqo4-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Pseudouridine synthase PUA domain-like 11
TGS-like ThrRS/AlaRS common domain 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Ferredoxin reductase-like, C-terminal NADP-linked domain 11
CBS-domain pair Nucleotide cyclase 11
Periplasmic binding protein-like II EAL domain-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
PLP-dependent transferases PLP-dependent transferases 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Tex N-terminal region-like RuvA domain 2-like 11
DNA-glycosylase Nudix 11
Class I glutamine amidotransferase-like ADC synthase 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
PHP14-like Phospholipase D/nuclease 11
MOP-like MOP-like 11
Tex N-terminal region-like Ribonuclease H-like 11
Ribonuclease H-like HRDC-like 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Nucleotidylyl transferase YegP-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Heme-dependent catalase-like Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases WGR domain-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Macro domain-like Zn-dependent exopeptidases 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
PPK N-terminal domain-like PHP14-like 11
"Winged helix" DNA-binding domain MOP-like 11
"Winged helix" DNA-binding domain C-terminal domain of transcriptional repressors 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Class II aaRS and biotin synthetases Translation proteins 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Fic-like "Winged helix" DNA-binding domain 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Zn-dependent exopeptidases LysM domain 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
HesB-like domain Fe-S cluster assembly (FSCA) domain-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Acyl-CoA N-acyltransferases (Nat) Glutathione synthetase ATP-binding domain-like 11
Periplasmic binding protein-like II Nucleotide cyclase 11
FliG FliG 11
L30e-like alpha/beta knot 11
CarD-like TRCF domain-like 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Periplasmic binding protein-like II ACT-like 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
Lysozyme-like LysM domain 11
THUMP domain-like Rhodanese/Cell cycle control phosphatase 11
JAB1/MPN domain Activating enzymes of the ubiquitin-like proteins 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Carbamate kinase-like ACT-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Adenine nucleotide alpha hydrolases-like GAF domain-like 11
LysM domain LysM domain 11
Nudix Thiamin phosphate synthase 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
TGS-like Class II aaRS ABD-related 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
L domain-like Protein kinase-like (PK-like) 11
ADC-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Trigger factor ribosome-binding domain FKBP-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Protein kinase-like (PK-like) vWA-like 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Fibronectin type III Pectin lyase-like 11
DNA topoisomerase I domain DNA breaking-rejoining enzymes 11
Starch-binding domain-like Galactose-binding domain-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
alpha/beta-Hydrolases beta-Roll 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Pectin lyase-like Autotransporter 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Acetyl-CoA synthetase-like NAD(P)-binding Rossmann-fold domains 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
GAF domain-like GAF domain-like 11
Homeodomain-like Probable bacterial effector-binding domain 11
S-adenosyl-L-methionine-dependent methyltransferases TPR-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
YajQ-like YajQ-like 11
PurS-like FGAM synthase PurL, linker domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
EAL domain-like CBS-domain pair 11
Ribonuclease H-like RuvA domain 2-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
PHP domain-like AF1531-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
Sm-like ribonucleoproteins cAMP-binding domain-like 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Molybdenum cofactor-binding domain Cytochrome c 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Galactose-binding domain-like Galactose-binding domain-like 11
Phoshotransferase/anion transport protein Phosphoenolpyruvate/pyruvate domain 11
GAF domain-like EAL domain-like 11
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 11
CoA-transferase family III (CaiB/BaiF) CoA-transferase family III (CaiB/BaiF) 11
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 11

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