SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

584 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2310
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 188
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 184
Actin-like ATPase domain Actin-like ATPase domain 164
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 163
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 154
GroES-like NAD(P)-binding Rossmann-fold domains 132
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 121
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 113
CheY-like C-terminal effector domain of the bipartite response regulators 101
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 102
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 92
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 84
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 82
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 85
ParB/Sulfiredoxin KorB DNA-binding domain-like 71
Thiolase-like Thiolase-like 71
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 74
"Winged helix" DNA-binding domain GAF domain-like 62
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 61
LysM domain LysM domain 64
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 64
P-loop containing nucleoside triphosphate hydrolases Translation proteins 65
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 61
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 51
Cupredoxins Cupredoxins 53
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 52
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 51
PYP-like sensor domain (PAS domain) Homeodomain-like 52
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 53
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 53
Sigma2 domain of RNA polymerase sigma factors C-terminal effector domain of the bipartite response regulators 51
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 52
Alpha-L RNA-binding motif Pseudouridine synthase 51
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 55
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 52
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 42
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 42
Phospholipase D/nuclease Phospholipase D/nuclease 44
Homeodomain-like Ribonuclease H-like 41
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 43
Calcium ATPase, transduction domain A HAD-like 43
Translation proteins EF-G C-terminal domain-like 43
PreATP-grasp domain Rudiment single hybrid motif 42
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 41
Trypsin-like serine proteases PDZ domain-like 43
Class II aaRS and biotin synthetases Class II aaRS ABD-related 43
DNA clamp DNA clamp 41
(Trans)glycosidases Glycosyl hydrolase domain 44
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 43
HAD-like Calcium ATPase, transmembrane domain M 43
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 42
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 41
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 42
MalF N-terminal region-like MetI-like 31
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 32
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 31
Single hybrid motif CoA-dependent acyltransferases 32
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 31
ACT-like ACT-like 32
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 31
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 31
PurM N-terminal domain-like PurM C-terminal domain-like 32
Galactose mutarotase-like (Trans)glycosidases 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 31
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 32
Homeodomain-like Homeodomain-like 32
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 31
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 32
Nucleotide cyclase EAL domain-like 33
Protease propeptides/inhibitors Subtilisin-like 31
P-loop containing nucleoside triphosphate hydrolases MOP-like 31
Lysozyme-like beta-lactamase/transpeptidase-like 33
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 31
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 31
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 21
Metallo-hydrolase/oxidoreductase Rhodanese/Cell cycle control phosphatase 22
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 21
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 22
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
PGBD-like L,D-transpeptidase catalytic domain-like 21
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 21
CheC-like Surface presentation of antigens (SPOA) 22
Penicillin binding protein dimerisation domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain 22
HMA, heavy metal-associated domain HAD-like 21
PYP-like sensor domain (PAS domain) Nucleotide cyclase 22
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 21
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 21
Cyclophilin-like PH0987 N-terminal domain-like 22
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
Oligoxyloglucan reducing end-specific cellobiohydrolase Oligoxyloglucan reducing end-specific cellobiohydrolase 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
Galactose mutarotase-like Glycosyl hydrolase domain 22
MFS general substrate transporter MFS general substrate transporter 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 21
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 22
"Winged helix" DNA-binding domain Thioesterase/thiol ester dehydrase-isomerase 22
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 21
FKBP-like Triger factor/SurA peptide-binding domain-like 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 22
Nucleic acid-binding proteins RuvA domain 2-like 22
Carbamate kinase-like ACT-like 21
"Winged helix" DNA-binding domain CBS-domain pair 22
HAMP domain-like PYP-like sensor domain (PAS domain) 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 22
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 22
Enolase N-terminal domain-like Enolase C-terminal domain-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 22
"Winged helix" DNA-binding domain Periplasmic binding protein-like I 21
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 21
Aldolase post-HMGL domain-like 22
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 21
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 21
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
GAF domain-like Nucleotide cyclase 22
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 21
"Winged helix" DNA-binding domain C-terminal domain of transcriptional repressors 22
E set domains (Trans)glycosidases 22
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 22
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 22
"Winged helix" DNA-binding domain Iron-dependent repressor protein, dimerization domain 22
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 22
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
Ribosomal protein S5 domain 2-like EF-G C-terminal domain-like 22
Regulatory protein AraC Homeodomain-like 21
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 21
TPR-like TPR-like 22
LysM domain Cysteine proteinases 21
"Winged helix" DNA-binding domain Actin-like ATPase domain 21
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
LysM domain (Trans)glycosidases 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 21
Thioredoxin-like Thioredoxin-like 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
4Fe-4S ferredoxins ADC-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
PLP-binding barrel Alanine racemase C-terminal domain-like 22
beta-lactamase/transpeptidase-like Penicillin-binding protein 2x (pbp-2x), c-terminal domain 22
2Fe-2S ferredoxin-like ADC-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 22
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 21
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 21
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 22
L30e-like alpha/beta knot 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
Glutathione synthetase ATP-binding domain-like Cyclophilin-like 11
HprK N-terminal domain-like PEP carboxykinase-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
PIN domain-like DNA/RNA polymerases 11
Rudiment single hybrid motif Single hybrid motif 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
(Trans)glycosidases Class I glutamine amidotransferase-like 11
PreATP-grasp domain Single hybrid motif 11
Ribonuclease H-like P-loop containing nucleoside triphosphate hydrolases 11
HprK N-terminal domain-like Thioesterase/thiol ester dehydrase-isomerase 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Nucleotide cyclase Nucleotide cyclase 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Cytidine deaminase-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
HprK N-terminal domain-like CBS-domain pair 11
Class II aaRS and biotin synthetases C-terminal domain of ProRS 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
CBS-domain pair Thioesterase/thiol ester dehydrase-isomerase 11
Carbamate kinase-like PUA domain-like 11
Nucleotidylyl transferase tRNA-binding arm 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
NAD(P)-binding Rossmann-fold domains ClpP/crotonase 11
Actin-like ATPase domain HD-domain/PDEase-like 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
DNA repair protein MutS, domain III SMR domain-like 11
RmlC-like cupins HD-domain/PDEase-like 11
Zinc beta-ribbon Zinc beta-ribbon 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain PYP-like sensor domain (PAS domain) 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
DPP6 N-terminal domain-like alpha/beta-Hydrolases 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Lysozyme-like Fibronectin type III 11
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, catalytic domain 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain Homodimeric domain of signal transducing histidine kinase 11
S-adenosyl-L-methionine-dependent methyltransferases PYP-like sensor domain (PAS domain) 11
Zinc beta-ribbon DNA primase core 11
PreATP-grasp domain PH0987 N-terminal domain-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Homocysteine S-methyltransferase FAD-linked oxidoreductase 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Translation proteins Translation proteins 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
Invasin/intimin cell-adhesion fragments Acid proteases 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
FucI/AraA N-terminal and middle domains FucI/AraA C-terminal domain-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
Methylesterase CheB, C-terminal domain PYP-like sensor domain (PAS domain) 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
HAMP domain-like HD-domain/PDEase-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
lambda repressor-like DNA-binding domains TPR-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Nudix Aldolase 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like PH0987 N-terminal domain-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
PYP-like sensor domain (PAS domain) HD-domain/PDEase-like 11
CarD-like TRCF domain-like 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Trypsin-like serine proteases Trypsin-like serine proteases 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
HD-domain/PDEase-like Nucleotidyltransferase 11
Galactose mutarotase-like Putative glucosidase YicI, C-terminal domain 11
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
beta-lactamase/transpeptidase-like Fibronectin type III 11
ISP domain Bet v1-like 11
AbrB/MazE/MraZ-like GAF domain-like 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
TGS-like Class II aaRS ABD-related 11
PTS-regulatory domain, PRD PTS system IIB component-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
GAF domain-like Homodimeric domain of signal transducing histidine kinase 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
PGBD-like PGBD-like 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
PheT/TilS domain Putative DNA-binding domain 11
Galactose mutarotase-like Galactose mutarotase-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Cytidine deaminase-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Histidine-containing phosphotransfer domain, HPT domain CheY-binding domain of CheA 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
YojJ-like RuvA domain 2-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
PTS-regulatory domain, PRD Phoshotransferase/anion transport protein 11
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
Translation proteins ThrRS/AlaRS common domain 11
RuvA domain 2-like BRCT domain 11
"Winged helix" DNA-binding domain Chorismate lyase-like 11
EAL domain-like BAS1536-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Galactose-binding domain-like (Trans)glycosidases 11
Formyltransferase FMT C-terminal domain-like 11
GroES-like GroES-like 11
E set domains Six-hairpin glycosidases 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Hsp33 domain HSP33 redox switch-like 11
Trigger factor ribosome-binding domain FKBP-like 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
CheY-binding domain of CheA CheW-like 11
PFL-like glycyl radical enzymes PFL-like glycyl radical enzymes 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
ACT-like Formyltransferase 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Class II aaRS and biotin synthetases Translation proteins 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Methylesterase CheB, C-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
"Winged helix" DNA-binding domain HprK N-terminal domain-like 11
Ribonuclease H-like TPR-like 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Cyclophilin-like Cyclophilin-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
lambda repressor-like DNA-binding domains P-loop containing nucleoside triphosphate hydrolases 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
PPK N-terminal domain-like PHP14-like 11
TGS-like ThrRS/AlaRS common domain 11
EAL domain-like GAF domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PIN domain-like Ribonuclease H-like 11
alpha-helical ferredoxin ARM repeat 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Nucleotide-diphospho-sugar transferases HCP-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like ClpP/crotonase 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
DeoB insert domain-like Alkaline phosphatase-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
PUA domain-like alpha/beta knot 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Serine metabolism enzymes domain ACT-like 11
HCP-like Flagellar export chaperone FliS 11
vWA-like vWA-like 11
(Trans)glycosidases Putative glucosidase YicI, C-terminal domain 11
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Tetrapyrrole methylase HemD-like 11
beta-Galactosidase/glucuronidase domain Galactose mutarotase-like 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
S-adenosyl-L-methionine-dependent methyltransferases Homodimeric domain of signal transducing histidine kinase 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
Galactose mutarotase-like Six-hairpin glycosidases 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins Ribonuclease H-like 11
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
HisI-like all-alpha NTP pyrophosphatases 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
CheY-binding domain of CheA ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PHP14-like Phospholipase D/nuclease 11
PH0987 N-terminal domain-like Single hybrid motif 11
lambda repressor-like DNA-binding domains Periplasmic binding protein-like II 11
LysM domain Lysozyme-like 11
E set domains Glycosyl hydrolase domain 11
YajQ-like YajQ-like 11
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 11
PreATP-grasp domain PreATP-grasp domain 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, peptide-binding domain 11
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Periplasmic binding protein-like II ACT-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Molybdenum cofactor biosynthesis proteins CinA-like 11
Nucleotide-diphospho-sugar transferases TPR-like 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Class II aaRS ABD-related C-terminal domain of ProRS 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
UROD/MetE-like UROD/MetE-like 11
GAF domain-like C-terminal effector domain of the bipartite response regulators 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
Ribosomal protein L6 Ribosomal protein L6 11
HD-domain/PDEase-like ACT-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Methylesterase CheB, C-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
THUMP domain-like Adenine nucleotide alpha hydrolases-like 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
PTS system IIB component-like Phoshotransferase/anion transport protein 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
GIY-YIG endonuclease RuvA domain 2-like 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
Cyclophilin-like Single hybrid motif 11
Nucleic acid-binding proteins PheT/TilS domain 11
Nucleotide cyclase HD-domain/PDEase-like 11
Obg GTP-binding protein N-terminal domain Obg GTP-binding protein C-terminal domain 11
lambda repressor-like DNA-binding domains RmlC-like cupins 11
TGS-like ACT-like 11
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
Thioredoxin-like Six-hairpin glycosidases 11
Glycosyl hydrolase domain Putative glucosidase YicI, C-terminal domain 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
P-loop containing nucleoside triphosphate hydrolases Obg GTP-binding protein C-terminal domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
AraD/HMP-PK domain-like NAD(P)-binding Rossmann-fold domains 11
Clc chloride channel CBS-domain pair 11
Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Pyrimidine nucleoside phosphorylase C-terminal domain Cytidine deaminase-like 11
DNA-glycosylase Nudix 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
TPR-like HD-domain/PDEase-like 11
Nucleic acid-binding proteins GAD domain-like 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
CheY-binding domain of CheA Homodimeric domain of signal transducing histidine kinase 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
beta-N-acetylhexosaminidase-like domain (Trans)glycosidases 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
PUA domain-like Nucleotidylyl transferase 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
Tetrapyrrole methylase all-alpha NTP pyrophosphatases 11
HIT-like HIT-like 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
E set domains E set domains 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
Ribonuclease H-like DNA/RNA polymerases 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Methylesterase CheB, C-terminal domain Homodimeric domain of signal transducing histidine kinase 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Iron-dependent repressor protein, dimerization domain C-terminal domain of transcriptional repressors 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Rudiment single hybrid motif PH0987 N-terminal domain-like 11
YrdC/RibB RibA-like 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
"Winged helix" DNA-binding domain PRTase-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Translation proteins Ribosomal protein S5 domain 2-like 11
SirA-like Rhodanese/Cell cycle control phosphatase 11
Class II aaRS and biotin synthetases GAD domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Transmembrane di-heme cytochromes Oxidoreductase molybdopterin-binding domain 11
PYP-like sensor domain (PAS domain) EAL domain-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
FliG FliG 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
"Winged helix" DNA-binding domain DnaD domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 11
Invasin/intimin cell-adhesion fragments Invasin/intimin cell-adhesion fragments 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Translation proteins PRC-barrel domain 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Nucleotidyltransferase TGS-like 11
Nucleotide-diphospho-sugar transferases Flagellar export chaperone FliS 11
lambda repressor-like DNA-binding domains LexA/Signal peptidase 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
TPR-like Cyclin-like 11
Respiratory nitrate reductase 1 gamma chain alpha-helical ferredoxin 11
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
HD-domain/PDEase-like TGS-like 11
"Winged helix" DNA-binding domain Bet v1-like 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 11
Galactose-binding domain-like Galactose mutarotase-like 11
Nucleotidyltransferase ACT-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Chaperone J-domain HSP40/DnaJ peptide-binding domain 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
RuBisCO, large subunit, small (N-terminal) domain RuBisCo, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain 11
MetI-like MetI-like 11
Methylesterase CheB, C-terminal domain Chemotaxis receptor methyltransferase CheR, N-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
GroEL-intermediate domain like GroEL apical domain-like 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Rudiment single hybrid motif Cyclophilin-like 11
Acyl-CoA dehydrogenase C-terminal domain-like Acyl-CoA dehydrogenase C-terminal domain-like 11
PHP domain-like RuvA domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
ClpP/crotonase ClpP/crotonase 11
TGS-like Class II aaRS and biotin synthetases 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
PreATP-grasp domain Cyclophilin-like 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
MoaD/ThiS Molybdopterin synthase subunit MoaE 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
"Winged helix" DNA-binding domain C-terminal domain of arginine repressor 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
RNase III domain-like dsRNA-binding domain-like 11
"Winged helix" DNA-binding domain Putative transcriptional regulator TM1602, C-terminal domain 11
YjeF N-terminal domain-like Ribokinase-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
lambda repressor-like DNA-binding domains lambda repressor-like DNA-binding domains 11
Nucleic acid-binding proteins BRCT domain 11

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