SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Granulibacter bethesdensis CGDNIH1

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

545 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 203
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 1812
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 159
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 104
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 102
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 102
beta-Roll beta-Roll 95
CheY-like C-terminal effector domain of the bipartite response regulators 92
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 86
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 74
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 65
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 61
Thioredoxin-like GST C-terminal domain-like 61
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 65
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
P-loop containing nucleoside triphosphate hydrolases Translation proteins 66
Actin-like ATPase domain Actin-like ATPase domain 63
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 65
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 65
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 64
GroES-like NAD(P)-binding Rossmann-fold domains 61
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 65
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 54
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 54
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 54
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 42
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 42
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 44
Nucleotide-diphospho-sugar transferases UDP-Glycosyltransferase/glycogen phosphorylase 43
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
E set domains (Trans)glycosidases 43
Folate-binding domain Aminomethyltransferase beta-barrel domain 43
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 43
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 44
FKBP-like Triger factor/SurA peptide-binding domain-like 43
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 42
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 43
Trypsin-like serine proteases PDZ domain-like 43
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 42
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 42
(Trans)glycosidases Glycosyl hydrolase domain 43
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 44
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
PreATP-grasp domain Rudiment single hybrid motif 42
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 43
ISP domain Bet v1-like 32
ACT-like ACT-like 33
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
Alpha-L RNA-binding motif Pseudouridine synthase 31
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 33
PurM N-terminal domain-like PurM C-terminal domain-like 33
E set domains Glycosyl hydrolase domain 32
CheY-like Homeodomain-like 32
Thiolase-like Thiolase-like 31
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Homodimeric domain of signal transducing histidine kinase CheY-like 33
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 31
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 31
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 33
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 33
Homeodomain-like Homeodomain-like 32
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 31
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 33
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 31
Lysozyme-like beta-lactamase/transpeptidase-like 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 33
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 33
Translation proteins EF-G C-terminal domain-like 33
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 33
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
PDZ domain-like PDZ domain-like 21
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
PLP-binding barrel Alanine racemase C-terminal domain-like 22
Macro domain-like Zn-dependent exopeptidases 21
P-loop containing nucleoside triphosphate hydrolases MOP-like 22
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 21
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 21
Subtilisin-like Galactose-binding domain-like 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Bacterial muramidases Lysozyme-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 22
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Nucleic acid-binding proteins RuvA domain 2-like 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 22
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 22
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 21
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 21
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
HAD-like Calcium ATPase, transmembrane domain M 22
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
Class I glutamine amidotransferase-like Homeodomain-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 22
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 22
CBS-domain pair FAD-binding/transporter-associated domain-like 21
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
PDZ domain-like ClpP/crotonase 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
CheY-like P-loop containing nucleoside triphosphate hydrolases 21
lambda repressor-like DNA-binding domains LexA/Signal peptidase 21
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 21
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 21
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 22
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 22
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 21
Nucleotidyltransferase HD-domain/PDEase-like 22
Nqo1 middle domain-like Nqo1C-terminal domain-like 22
Galactose mutarotase-like E set domains 21
TPR-like TPR-like 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
FAD/NAD(P)-binding domain Folate-binding domain 21
Phospholipase D/nuclease Phospholipase D/nuclease 22
S-adenosyl-L-methionine-dependent methyltransferases UDP-Glycosyltransferase/glycogen phosphorylase 22
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 22
Calcium ATPase, transduction domain A HAD-like 22
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
Single hybrid motif CoA-dependent acyltransferases 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 22
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 22
Subtilisin-like beta-Roll 22
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 21
Galactose-binding domain-like beta-Roll 22
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 22
GAF domain-like Homodimeric domain of signal transducing histidine kinase 22
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 22
Phoshotransferase/anion transport protein HPr-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Ribonuclease H-like HRDC-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
RuvA domain 2-like BRCT domain 11
Aldolase Tetrahydrobiopterin biosynthesis enzymes-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
PYP-like sensor domain (PAS domain) CheY-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Rudiment single hybrid motif PH0987 N-terminal domain-like 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
alpha/beta-Hydrolases alpha/beta-Hydrolases 11
Ctag/Cox11 Cytochrome c 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Hsp33 domain HSP33 redox switch-like 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Acetyl-CoA synthetase-like Trimeric LpxA-like enzymes 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Zinc beta-ribbon DNA primase core 11
Origin of replication-binding domain, RBD-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
2Fe-2S ferredoxin-like ADC-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
Cyclophilin-like Single hybrid motif 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Translation proteins Translation proteins 11
"Winged helix" DNA-binding domain HRDC-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Methylesterase CheB, C-terminal domain PYP-like sensor domain (PAS domain) 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Cyclophilin-like Cyclophilin-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Nudix "Winged helix" DNA-binding domain 11
GAF domain-like CheY-like 11
PreATP-grasp domain Single hybrid motif 11
HD-domain/PDEase-like ACT-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Homeodomain-like Probable bacterial effector-binding domain 11
Rudiment single hybrid motif Single hybrid motif 11
"Winged helix" DNA-binding domain GAF domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
PheT/TilS domain Putative DNA-binding domain 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Ribosomal protein L6 Ribosomal protein L6 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Glycerol-3-phosphate (1)-acyltransferase Acetyl-CoA synthetase-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
4Fe-4S ferredoxins ADC-like 11
Nucleic acid-binding proteins GAD domain-like 11
Nucleotidyltransferase ACT-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
HRDC-like HRDC-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
FAD-linked oxidoreductase ALDH-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Pectin lyase-like Pectin lyase-like 11
PIN domain-like DNA/RNA polymerases 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 11
Heme-dependent catalase-like Class I glutamine amidotransferase-like 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
Phoshotransferase/anion transport protein Phosphoenolpyruvate/pyruvate domain 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
FAD/NAD(P)-binding domain Thioredoxin-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
PHP14-like Phospholipase D/nuclease 11
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
GAF domain-like Phosphohistidine domain 11
OMPA-like OmpA-like 11
GroEL-intermediate domain like GroEL apical domain-like 11
Acyl-CoA N-acyltransferases (Nat) Nudix 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
PIN domain-like Ribonuclease H-like 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Translation proteins PRC-barrel domain 11
lambda repressor-like DNA-binding domains RmlC-like cupins 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 11
RuvA domain 2-like JAB1/MPN domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
DNA clamp DNA clamp 11
Rudiment single hybrid motif Cyclophilin-like 11
Nucleic acid-binding proteins BRCT domain 11
Periplasmic binding protein-like II Periplasmic binding protein-like II 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Periplasmic binding protein-like II MetI-like 11
CarD-like TRCF domain-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain PYP-like sensor domain (PAS domain) 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Cupredoxins Cupredoxins 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
GAF domain-like GAF domain-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Trimeric LpxA-like enzymes Trimeric LpxA-like enzymes 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
TerB-like Chaperone J-domain 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors CheY-like 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Single hybrid motif Thiamin diphosphate-binding fold (THDP-binding) 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
alpha-helical ferredoxin Nucleotide-binding domain 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
Nucleotidyltransferase TGS-like 11
Methylesterase CheB, C-terminal domain Chemotaxis receptor methyltransferase CheR, N-terminal domain 11
Periplasmic binding protein-like II Voltage-gated potassium channels 11
Molybdenum cofactor biosynthesis proteins Nucleotide-diphospho-sugar transferases 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
PreATP-grasp domain PH0987 N-terminal domain-like 11
HPr-like Phosphohistidine domain 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
TGS-like Class II aaRS and biotin synthetases 11
Ribonuclease H-like DNA/RNA polymerases 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Formylmethanofuran:tetrahydromethanopterin formyltransferase Formylmethanofuran:tetrahydromethanopterin formyltransferase 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
"Winged helix" DNA-binding domain Iron-dependent repressor protein, dimerization domain 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Ribokinase-like Nucleotidylyl transferase 11
Aldolase SIS domain 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
CheY-like CheY-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
PK beta-barrel domain-like PK C-terminal domain-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
PYP-like sensor domain (PAS domain) GAF domain-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 11
CRISPR-associated protein CRISPR-associated protein 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
HMA, heavy metal-associated domain HAD-like 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
YjeF N-terminal domain-like Ribokinase-like 11
MFS general substrate transporter Acetyl-CoA synthetase-like 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
YlxR-like L30e-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
ACP-like Trimeric LpxA-like enzymes 11
Cytochrome c Cytochrome c 11
GroEL equatorial domain-like GroEL apical domain-like 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
Glycosyl hydrolase domain Protein kinase-like (PK-like) 11
Carbamate kinase-like PUA domain-like 11
Formyltransferase FMT C-terminal domain-like 11
Clc chloride channel CBS-domain pair 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Phoshotransferase/anion transport protein Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
MetI-like MetI-like 11
HlyD-like secretion proteins HlyD-like secretion proteins 11
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 11
Acetyl-CoA synthetase-like ACP-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Methylesterase CheB, C-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
FKBP-like FKBP-like 11
Translation proteins ThrRS/AlaRS common domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Nqo5-like HydB/Nqo4-like 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
S-adenosyl-L-methionine-dependent methyltransferases PYP-like sensor domain (PAS domain) 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
Glutathione synthetase ATP-binding domain-like PH0987 N-terminal domain-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
TTHA1013/TTHA0281-like Ribbon-helix-helix 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Radical SAM enzymes RuvA domain 2-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
PPK N-terminal domain-like PHP14-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
YrdC/RibB RibA-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Carbamate kinase-like ACT-like 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
HCP-like HCP-like 11
PH0987 N-terminal domain-like Single hybrid motif 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Phoshotransferase/anion transport protein Phosphohistidine domain 11
PUA domain-like alpha/beta knot 11
S-adenosyl-L-methionine-dependent methyltransferases Nucleotide-diphospho-sugar transferases 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Globin-like Riboflavin synthase domain-like 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Nucleotidylyl transferase tRNA-binding arm 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
UROD/MetE-like UROD/MetE-like 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
TGS-like ThrRS/AlaRS common domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Class II aaRS and biotin synthetases GAD domain-like 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Single hybrid motif TK C-terminal domain-like 11
L30e-like alpha/beta knot 11
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
HPr-like Phosphoenolpyruvate/pyruvate domain 11
Thioredoxin-like TPR-like 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Trigger factor ribosome-binding domain FKBP-like 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
PreATP-grasp domain PreATP-grasp domain 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
E set domains E set domains 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
PreATP-grasp domain Methylglyoxal synthase-like 11
P-loop containing nucleoside triphosphate hydrolases Dehydroquinate synthase-like 11
Glutathione synthetase ATP-binding domain-like Cyclophilin-like 11
HD-domain/PDEase-like TGS-like 11
Periplasmic binding protein-like II ACT-like 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
PreATP-grasp domain Cyclophilin-like 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Class I glutamine amidotransferase-like ADC synthase 11
Nucleic acid-binding proteins PheT/TilS domain 11
Creatinase/prolidase N-terminal domain Creatinase/prolidase N-terminal domain 11
TGS-like Class II aaRS ABD-related 11
Cyclophilin-like PH0987 N-terminal domain-like 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Pectin lyase-like beta-Roll 11
RmlC-like cupins Homeodomain-like 11
alpha/beta-Hydrolases AhpD-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Acid proteases Acid proteases 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase Riboflavin kinase-like 11
GAF domain-like Nucleotide cyclase 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
Class II aaRS and biotin synthetases Translation proteins 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidyltransferase Nucleotidyltransferase 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Thioredoxin-like Six-hairpin glycosidases 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
RNase III domain-like dsRNA-binding domain-like 11
Inosine monophosphate dehydrogenase (IMPDH) Nitrite and sulphite reductase 4Fe-4S domain-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11

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