SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Desulfobacterium autotrophicum HRM2

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


Add or remove domain pairs

The links below permit the addition or removal of specific sets of domain combination pairs.


Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Add or remove genomes

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Add or remove genomes:
Include genomes:
Exclude genomes:


Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

826 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 7843
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 4932
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 4711
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 4630
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 4018
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 3424
Homodimeric domain of signal transducing histidine kinase CheY-like 3324
PYP-like sensor domain (PAS domain) CheY-like 2618
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 2519
CheY-like P-loop containing nucleoside triphosphate hydrolases 234
CheY-like Homeodomain-like 212
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 219
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 194
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 197
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 174
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 165
PYP-like sensor domain (PAS domain) Homeodomain-like 165
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 166
Actin-like ATPase domain Actin-like ATPase domain 154
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 142
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 131
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 135
P-loop containing nucleoside triphosphate hydrolases MOP-like 121
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 126
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 126
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 127
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 119
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 1111
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 115
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 116
TPR-like TPR-like 118
CheY-like C-terminal effector domain of the bipartite response regulators 111
Aldehyde ferredoxin oxidoreductase, N-terminal domain Aldehyde ferredoxin oxidoreductase, C-terminal domains 113
P-loop containing nucleoside triphosphate hydrolases Translation proteins 106
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 105
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 105
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 105
alpha-helical ferredoxin Nucleotide-binding domain 1010
Succinyl-CoA synthetase domains Glutathione synthetase ATP-binding domain-like 104
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 105
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 93
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 97
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 93
GAF domain-like PYP-like sensor domain (PAS domain) 97
GAF domain-like Homodimeric domain of signal transducing histidine kinase 97
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 94
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 93
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 94
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 93
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 87
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 85
PYP-like sensor domain (PAS domain) Nucleotide cyclase 86
4Fe-4S ferredoxins Nucleotide-binding domain 88
alpha-helical ferredoxin alpha-helical ferredoxin 88
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 83
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 83
ACT-like ACT-like 83
CheY-like CheY-like 75
4Fe-4S ferredoxins alpha-helical ferredoxin 77
PLP-binding barrel Alanine racemase C-terminal domain-like 73
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 75
HAMP domain-like PYP-like sensor domain (PAS domain) 74
GroES-like NAD(P)-binding Rossmann-fold domains 74
Thiolase-like Thiolase-like 74
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 64
4Fe-4S ferredoxins 4Fe-4S ferredoxins 65
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 66
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 62
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 65
Calcium ATPase, transmembrane domain M HAD-like 66
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 63
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 65
TrkA C-terminal domain-like TrkA C-terminal domain-like 64
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 63
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 62
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 61
CheY-like HD-domain/PDEase-like 64
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 61
Translation proteins EF-G C-terminal domain-like 63
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 63
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 62
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 63
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 53
lambda repressor-like DNA-binding domains RmlC-like cupins 51
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 53
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 55
Periplasmic binding protein-like II PYP-like sensor domain (PAS domain) 53
Calcium ATPase, transduction domain A HAD-like 55
EF-G C-terminal domain-like EF-G C-terminal domain-like 52
Histidine-containing phosphotransfer domain, HPT domain CheY-like 54
PurM N-terminal domain-like PurM C-terminal domain-like 52
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 53
CheY-like Nucleotide cyclase 55
Resolvase-like Homeodomain-like 51
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 55
Nucleotide-binding domain Nucleotide-binding domain 55
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 55
Thiamin diphosphate-binding fold (THDP-binding) 4Fe-4S ferredoxins 54
Nucleotide cyclase EAL domain-like 55
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 53
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 51
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 53
NagB/RpiA/CoA transferase-like Acyl-CoA N-acyltransferases (Nat) 52
PUA domain-like Ribosomal protein S5 domain 2-like 52
GAF domain-like HD-domain/PDEase-like 55
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 53
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 55
Sensory domain-like PYP-like sensor domain (PAS domain) 44
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 43
ClpP/crotonase ClpP/crotonase 41
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 41
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 41
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 43
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 43
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 44
Nucleic acid-binding proteins Nucleic acid-binding proteins 43
GAF domain-like Homeodomain-like 42
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 41
Lysozyme-like beta-lactamase/transpeptidase-like 43
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 42
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 43
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 42
HAMP domain-like CheY-like 43
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 41
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 44
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 41
Respiratory nitrate reductase 1 gamma chain alpha-helical ferredoxin 44
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III Thiamin diphosphate-binding fold (THDP-binding) 43
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 32
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 33
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 33
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 31
FKBP-like Triger factor/SurA peptide-binding domain-like 33
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 32
GAF domain-like Nucleotide cyclase 32
4Fe-4S ferredoxins Fe-only hydrogenase 33
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III TK C-terminal domain-like 32
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 32
Translation proteins SH3-like domain Nucleic acid-binding proteins 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 32
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 32
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
PDZ domain-like ClpP/crotonase 32
4Fe-4S ferredoxins Nitrite and sulphite reductase 4Fe-4S domain-like 32
P-loop containing nucleoside triphosphate hydrolases TPR-like 33
Thiolase-like FabD/lysophospholipase-like 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 32
cAMP-binding domain-like "Winged helix" DNA-binding domain 31
DNA methylase specificity domain DNA methylase specificity domain 32
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
ADC-like 4Fe-4S ferredoxins 32
Periplasmic binding protein-like II GAF domain-like 31
MetI-like MetI-like 32
Translation proteins Ribosomal protein S5 domain 2-like 31
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 33
TK C-terminal domain-like 4Fe-4S ferredoxins 32
Chaperone J-domain HSP40/DnaJ peptide-binding domain 33
Aspartate/glutamate racemase Aspartate/glutamate racemase 31
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 32
Pectin lyase-like Pectin lyase-like 33
Periplasmic binding protein-like II CheY-like 32
Ferritin-like Rubredoxin-like 31
Nucleotide-binding domain FAD/NAD(P)-binding domain 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 31
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 32
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
Formate dehydrogenase/DMSO reductase, domains 1-3 4Fe-4S ferredoxins 32
RuvA domain 2-like Nucleic acid-binding proteins 33
PYP-like sensor domain (PAS domain) EAL domain-like 33
P-loop containing nucleoside triphosphate hydrolases Phospholipase D/nuclease 33
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 32
Enolase N-terminal domain-like Enolase C-terminal domain-like 32
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 32
tRNA-binding arm Class II aaRS and biotin synthetases 21
HAMP domain-like Nucleotide cyclase 21
Tryptophan synthase beta subunit-like PLP-dependent enzymes Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 21
Homeodomain-like Ribonuclease H-like 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
Clc chloride channel CBS-domain pair 21
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 21
Activating enzymes of the ubiquitin-like proteins FMN-dependent nitroreductase-like 21
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
Tryptophan synthase beta subunit-like PLP-dependent enzymes Nucleotidylyl transferase 21
Thiolase-like NAD(P)-binding Rossmann-fold domains 22
"Winged helix" DNA-binding domain Iron-dependent repressor protein, dimerization domain 22
P-loop containing nucleoside triphosphate hydrolases C-type lectin-like 22
Sensory domain-like HAMP domain-like 22
ACP-like ACP-like 22
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 21
HIT-like HIT-like 21
CheY-like PP2C-like 22
vWA-like OmpA-like 22
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 22
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 21
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 21
Cobalamin (vitamin B12)-binding domain Radical SAM enzymes 21
P-loop containing nucleoside triphosphate hydrolases TGS-like 21
DHH phosphoesterases CBS-domain pair 22
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 22
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Carbamate kinase-like ACT-like 21
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 21
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 22
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Nitrite/Sulfite reductase N-terminal domain-like 4Fe-4S ferredoxins 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 22
HD-domain/PDEase-like ACT-like 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
Metallo-hydrolase/oxidoreductase Flavoproteins 21
"Winged helix" DNA-binding domain Chorismate lyase-like 21
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
MgtE N-terminal domain-like MgtE membrane domain-like 21
FMN-dependent nitroreductase-like FMN-dependent nitroreductase-like 21
2Fe-2S ferredoxin-like Actin-like ATPase domain 22
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 22
Bet v1-like NAD(P)-binding Rossmann-fold domains 21
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 21
Sensory domain-like Sensory domain-like 22
CO dehydrogenase ISP C-domain like CO dehydrogenase molybdoprotein N-domain-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
4Fe-4S ferredoxins FMN-dependent nitroreductase-like 21
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 21
CheY-like Methylesterase CheB, C-terminal domain 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
CheY-like Glutathione synthetase ATP-binding domain-like 21
4Fe-4S ferredoxins Radical SAM enzymes 21
Ribonuclease H-like DNA/RNA polymerases 22
CheY-like EAL domain-like 22
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 21
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 22
CheY-like CBS-domain pair 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Voltage-gated potassium channels TrkA C-terminal domain-like 22
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
4Fe-4S ferredoxins P-loop containing nucleoside triphosphate hydrolases 21
Cobalamin (vitamin B12)-binding domain Cobalamin (vitamin B12)-dependent enzymes 22
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
MoeA N-terminal region -like MoeA C-terminal domain-like 22
MgtE N-terminal domain-like CBS-domain pair 21
Rhodanese/Cell cycle control phosphatase Ferritin-like 21
Radical SAM enzymes Nitrogenase accessory factor-like 21
Alpha-L RNA-binding motif Pseudouridine synthase 21
FAD/NAD(P)-binding domain alpha-helical ferredoxin 22
Nucleotidyltransferase HD-domain/PDEase-like 22
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 21
Histidine-containing phosphotransfer domain, HPT domain CheW-like 22
Calcium ATPase, transmembrane domain M Metal cation-transporting ATPase, ATP-binding domain N 22
2Fe-2S ferredoxin-like Molybdenum cofactor-binding domain 21
(Trans)glycosidases Glycosyl hydrolase domain 22
Thiolase-like Thioesterase/thiol ester dehydrase-isomerase 22
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 22
PUA domain-like Nucleotidylyl transferase 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HD-domain/PDEase-like 22
Homodimeric domain of signal transducing histidine kinase CheW-like 22
ParB/Sulfiredoxin S-adenosyl-L-methionine-dependent methyltransferases 22
NagB/RpiA/CoA transferase-like 4Fe-4S ferredoxins 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 21
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
RuvA domain 2-like P-loop containing nucleoside triphosphate hydrolases 21
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 22
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
Nqo1 FMN-binding domain-like alpha-helical ferredoxin 21
ParB/Sulfiredoxin KorB DNA-binding domain-like 22
FabD/lysophospholipase-like Thioesterase/thiol ester dehydrase-isomerase 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 21
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 22
HMA, heavy metal-associated domain HAD-like 22
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
CBS-domain pair MgtE membrane domain-like 21
2Fe-2S ferredoxin-like ADC-like 21
Homodimeric domain of signal transducing histidine kinase HD-domain/PDEase-like 22
cAMP-binding domain-like Protein kinase-like (PK-like) 21
Respiratory nitrate reductase 1 gamma chain Respiratory nitrate reductase 1 gamma chain 22
"Winged helix" DNA-binding domain C-terminal domain of transcriptional repressors 22
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 21
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 22
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 22
ACP-like NAD(P)-binding Rossmann-fold domains 22
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 22
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 22
TPR-like S-adenosyl-L-methionine-dependent methyltransferases 22
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 22
Formiminotransferase domain of formiminotransferase-cyclodeaminase. Methenyltetrahydrofolate cyclohydrolase-like 21
Lysozyme-like LysM domain 22
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 21
CheY-like GAF domain-like 22
Glutathione synthetase ATP-binding domain-like Acyl-CoA N-acyltransferases (Nat) 21
2Fe-2S ferredoxin-like CO dehydrogenase molybdoprotein N-domain-like 21
Thiolase-like ACP-like 22
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 22
CO dehydrogenase ISP C-domain like Molybdenum cofactor-binding domain 21
FabD/lysophospholipase-like ACP-like 22
Ribonuclease H-like P-loop containing nucleoside triphosphate hydrolases 22
Nucleotidyltransferase ACT-like 22
Formiminotransferase domain of formiminotransferase-cyclodeaminase. Formiminotransferase domain of formiminotransferase-cyclodeaminase. 21
4Fe-4S ferredoxins FMN-linked oxidoreductases 11
FMN-binding split barrel UbiD C-terminal domain-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Nudix Nudix 11
GroEL-intermediate domain like GroEL apical domain-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Acyl-CoA N-acyltransferases (Nat) 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Purple acid phosphatase, N-terminal domain Metallo-dependent phosphatases 11
RuvA domain 2-like BRCT domain 11
Serine metabolism enzymes domain ACT-like 11
Nqo5-like HydB/Nqo4-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
ALDH-like Acetyl-CoA synthetase-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
ACT-like HAD-like 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Macro domain-like Zn-dependent exopeptidases 11
ACT-like 4Fe-4S ferredoxins 11
PTS system IIB component-like Phosphohistidine domain 11
PurS-like PurM N-terminal domain-like 11
Aldolase Single hybrid motif 11
TGS-like Class II aaRS and biotin synthetases 11
Acyl-CoA dehydrogenase NM domain-like Rubredoxin-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Class II aaRS and biotin synthetases SufE/NifU 11
YjeF N-terminal domain-like Ribokinase-like 11
GAF domain-like Phosphohistidine domain 11
N-acetylmuramoyl-L-alanine amidase-like Caspase-like 11
S-adenosyl-L-methionine-dependent methyltransferases Nucleotide-diphospho-sugar transferases 11
PH0987 N-terminal domain-like Cyclophilin-like 11
4Fe-4S ferredoxins ARM repeat 11
Cysteine proteinases alpha/beta-Hydrolases 11
CarD-like TRCF domain-like 11
Single hybrid motif CoA-dependent acyltransferases 11
PreATP-grasp domain PreATP-grasp domain 11
Flavoproteins Phosphotyrosine protein phosphatases I 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
Inosine monophosphate dehydrogenase (IMPDH) Inosine monophosphate dehydrogenase (IMPDH) 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
TorD-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Radical SAM enzymes "Winged helix" DNA-binding domain 11
2Fe-2S ferredoxin-like Fe-only hydrogenase 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
MCP/YpsA-like Homodimeric domain of signal transducing histidine kinase 11
HAMP domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
NAD(P)-binding Rossmann-fold domains PYP-like sensor domain (PAS domain) 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases "Helical backbone" metal receptor 11
Thioredoxin-like 4Fe-4S ferredoxins 11
Nucleic acid-binding proteins GAD domain-like 11
TrkA C-terminal domain-like Phoshotransferase/anion transport protein 11
Putative DNA-binding domain Phoshotransferase/anion transport protein 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
TorD-like ADC-like 11
HD-domain/PDEase-like Nucleotide cyclase 11
CheY-like TPR-like 11
Porins Porins 11
Phage tail proteins gp5 N-terminal domain-like 11
Acyl-CoA dehydrogenase C-terminal domain-like Rubredoxin-like 11
Homeodomain-like DNA-glycosylase 11
MCP/YpsA-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PHP domain-like AF1531-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Nucleotidylyl transferase P-loop containing nucleoside triphosphate hydrolases 11
GIY-YIG endonuclease RuvA domain 2-like 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
C-terminal effector domain of the bipartite response regulators TPR-like 11
Nucleotidylyl transferase tRNA-binding arm 11
PheT/TilS domain Putative DNA-binding domain 11
Tetrapyrrole methylase HemD-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
EspE N-terminal domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
UbiD C-terminal domain-like UbiD C-terminal domain-like 11
DNA-glycosylase Nudix 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Outer membrane efflux proteins (OEP) 11
4Fe-4S ferredoxins CheY-like 11
ClpP/crotonase NfeD domain-like 11
cAMP-binding domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
MoeA C-terminal domain-like Periplasmic binding protein-like II 11
CheY-like Nucleotide-binding domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
YrdC/RibB RibA-like 11
Glutathione synthetase ATP-binding domain-like TrkA C-terminal domain-like 11
Nucleotide cyclase TPR-like 11
Glycerol-3-phosphate (1)-acyltransferase NAD(P)-binding Rossmann-fold domains 11
Hsp33 domain HSP33 redox switch-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) 11
UDP-Glycosyltransferase/glycogen phosphorylase Acyl-CoA N-acyltransferases (Nat) 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
TerB-like Chaperone J-domain 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
CNF1/YfiH-like putative cysteine hydrolases HD-domain/PDEase-like 11
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Glycerol-3-phosphate (1)-acyltransferase alpha/beta-Hydrolases 11
Metallo-dependent phosphatases Multiheme cytochromes 11
Nucleic acid-binding proteins BRCT domain 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
Thioredoxin-like ARM repeat 11
RuvA domain 2-like MCP/YpsA-like 11
TPR-like Periplasmic binding protein-like I 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Acyl-CoA N-acyltransferases (Nat) 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
PTS system IIB component-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Zinc beta-ribbon Zinc beta-ribbon 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Lysozyme-like Nucleic acid-binding proteins 11
RNase III domain-like dsRNA-binding domain-like 11
CheW-like CheY-like 11
TPR-like Sporulation related repeat 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Barwin-like endoglucanases Sporulation related repeat 11
Methyl-accepting chemotaxis protein (MCP) signaling domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PHP domain-like P-loop containing nucleoside triphosphate hydrolases 11
Multidrug efflux transporter AcrB transmembrane domain Outer membrane efflux proteins (OEP) 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Periplasmic binding protein-like II Lysozyme-like 11
PLP-dependent transferases Aldehyde ferredoxin oxidoreductase, C-terminal domains 11
Ribonuclease H-like HRDC-like 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
PreATP-grasp domain N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 11
CBS-domain pair Nucleotidyltransferase 11
Guanido kinase N-terminal domain Glutamine synthetase/guanido kinase 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Class II aaRS and biotin synthetases Translation proteins 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Phase 1 flagellin Trimeric LpxA-like enzymes 11
Nqo1C-terminal domain-like 4Fe-4S ferredoxins 11
NAD(P)-linked oxidoreductase alpha-helical ferredoxin 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Inosine monophosphate dehydrogenase (IMPDH) FabD/lysophospholipase-like 11
CheY-like SpoIIaa-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
NAD(P)-binding Rossmann-fold domains Phoshotransferase/anion transport protein 11
HAMP domain-like GAF domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
CbiG N-terminal domain-like CobE/GbiG C-terminal domain-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
NAD(P)-binding Rossmann-fold domains ClpP/crotonase 11
Radical SAM enzymes TPR-like 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Zinc beta-ribbon DNA primase core 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
PIN domain-like DNA/RNA polymerases 11
Cobalamin (vitamin B12)-binding domain P-loop containing nucleoside triphosphate hydrolases 11
PYP-like sensor domain (PAS domain) HD-domain/PDEase-like 11
vWA-like TSP type-3 repeat 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Inosine monophosphate dehydrogenase (IMPDH) Thiolase-like 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Rhomboid-like HSP40/DnaJ peptide-binding domain 11
Ribonuclease H-like BRCT domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
PLP-dependent transferases Aldehyde ferredoxin oxidoreductase, N-terminal domain 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
Phoshotransferase/anion transport protein Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Acyl-CoA N-acyltransferases (Nat) Carbon-nitrogen hydrolase 11
Nucleotidyltransferase Nucleotidyltransferase 11
FAD/NAD(P)-binding domain Rhodanese/Cell cycle control phosphatase 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
PHP domain-like dsRNA-binding domain-like 11
TTHA1013/TTHA0281-like Ribbon-helix-helix 11
ARM repeat ARM repeat 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
TPR-like HCP-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Chorismate mutase II Periplasmic binding protein-like II 11
Chorismate mutase II 6-phosphogluconate dehydrogenase C-terminal domain-like 11
Peptide methionine sulfoxide reductase Mss4-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal effector domain of the bipartite response regulators 11
Periplasmic binding protein-like II Periplasmic binding protein-like II 11
Aldolase AFP III-like domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 11
P-loop containing nucleoside triphosphate hydrolases Cobalamin (vitamin B12)-dependent enzymes 11
NAD(P)-binding Rossmann-fold domains Homodimeric domain of signal transducing histidine kinase 11
Tex N-terminal region-like Ribonuclease H-like 11
Glutathione synthetase ATP-binding domain-like N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 11
Nucleotide cyclase P-loop containing nucleoside triphosphate hydrolases 11
Chorismate mutase II ACT-like 11
Phospholipase D/nuclease LexA/Signal peptidase 11
Formyltransferase FMT C-terminal domain-like 11
NTF2-like Nucleotide cyclase 11
ARM repeat CheY-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
NosL/MerB-like NosL/MerB-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
EspE N-terminal domain-like Homodimeric domain of signal transducing histidine kinase 11
(Trans)glycosidases Six-hairpin glycosidases 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 4Fe-4S ferredoxins 11
DHS-like NAD/FAD-binding domain DHS-like NAD/FAD-binding domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Inosine monophosphate dehydrogenase (IMPDH) Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Nucleotide-diphospho-sugar transferases Protein kinase-like (PK-like) 11
HRDC-like HRDC-like 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
PHP domain-like UDP-Glycosyltransferase/glycogen phosphorylase 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Nqo1C-terminal domain-like alpha-helical ferredoxin 11
GroES-like Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) 11
EAL domain-like HD-domain/PDEase-like 11
PDZ domain-like PDZ domain-like 11
L30e-like alpha/beta knot 11
Cysteine proteinases Porins 11
HlyD-like secretion proteins HlyD-like secretion proteins 11
E set domains (Trans)glycosidases 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
HPr-like Phosphohistidine domain 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 11
Phospholipase D/nuclease Phospholipase D/nuclease 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Nucleotide cyclase CBD9-like 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain "Winged helix" DNA-binding domain 11
Nqo1 middle domain-like 4Fe-4S ferredoxins 11
C-type lectin-like S-adenosyl-L-methionine-dependent methyltransferases 11
Cytochrome c Cytochrome c 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
DHH phosphoesterases Nucleotidyltransferase 11
Ligand-binding domain in the NO signalling and Golgi transport Nucleotide cyclase 11
Inosine monophosphate dehydrogenase (IMPDH) ACP-like 11
MFS general substrate transporter Homodimeric domain of signal transducing histidine kinase 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
P-loop containing nucleoside triphosphate hydrolases OmpA-like 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Phosphofructokinase Phosphofructokinase 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
ABC transporter involved in vitamin B12 uptake, BtuC "Winged helix" DNA-binding domain 11
Histidine-containing phosphotransfer domain, HPT domain EspE N-terminal domain-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Sensory domain-like GAF domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
DNA clamp DNA clamp 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase Thioesterase/thiol ester dehydrase-isomerase 11
Thioredoxin-like Six-hairpin glycosidases 11
Collagen-binding domain Subtilisin-like 11
SirA-like DsrEFH-like 11
PTS system IIB component-like Phoshotransferase/anion transport protein 11
MFS general substrate transporter ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 11
ParB/Sulfiredoxin Dimeric alpha+beta barrel 11
Fe-only hydrogenase HprK N-terminal domain-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
P-loop containing nucleoside triphosphate hydrolases LexA/Signal peptidase 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
P-loop containing nucleoside triphosphate hydrolases PGBD-like 11
Protein kinase-like (PK-like) TPR-like 11
PGBD-like L,D-transpeptidase catalytic domain-like 11
Chorismate mutase II NAD(P)-binding Rossmann-fold domains 11
Aldolase post-HMGL domain-like 11
Class II aaRS ABD-related C-terminal domain of ProRS 11
OsmC-like OsmC-like 11
Nucleotide-diphospho-sugar transferases UDP-Glycosyltransferase/glycogen phosphorylase 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
4Fe-4S ferredoxins HprK N-terminal domain-like 11
Thioredoxin-like Nqo1 middle domain-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
CheW-like CheW-like 11
Lipovitellin-phosvitin complex, superhelical domain CheY-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
CBS-domain pair FAD-binding/transporter-associated domain-like 11
Alpha subunit of glutamate synthase, C-terminal domain 4Fe-4S ferredoxins 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
RuvA domain 2-like RuvA domain 2-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Homeodomain-like TATA-box binding protein-like 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
GroEL equatorial domain-like GroEL apical domain-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Ribonuclease H-like RuvA domain 2-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Alpha subunit of glutamate synthase, C-terminal domain FAD/NAD(P)-binding domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
KorB DNA-binding domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Class II aaRS and biotin synthetases GAD domain-like 11
CBS-domain pair PYP-like sensor domain (PAS domain) 11
Pili subunits GspK insert domain-like 11
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 11
PIN domain-like Ribonuclease H-like 11
Tex N-terminal region-like RuvA domain 2-like 11
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 11
CBS-domain pair Homeodomain-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like ClpP/crotonase 11
HD-domain/PDEase-like HD-domain/PDEase-like 11
"Winged helix" DNA-binding domain GAF domain-like 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Nucleic acid-binding proteins PheT/TilS domain 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
Trypsin-like serine proteases PDZ domain-like 11
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Thioesterase/thiol ester dehydrase-isomerase 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
"Winged helix" DNA-binding domain Formate dehydrogenase/DMSO reductase, domains 1-3 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
cAMP-binding domain-like FabD/lysophospholipase-like 11
HD-domain/PDEase-like TGS-like 11
ABC transporter involved in vitamin B12 uptake, BtuC Iron-dependent repressor protein, dimerization domain 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
TATA-box binding protein-like DNA-glycosylase 11
PreATP-grasp domain Rudiment single hybrid motif 11
"Winged helix" DNA-binding domain ADC-like 11
Nqo1 FMN-binding domain-like 4Fe-4S ferredoxins 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 11
S-adenosyl-L-methionine-dependent methyltransferases UDP-Glycosyltransferase/glycogen phosphorylase 11
Molybdenum cofactor biosynthesis proteins CinA-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
P-loop containing nucleoside triphosphate hydrolases cAMP-binding domain-like 11
EspE N-terminal domain-like CheW-like 11
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Outer membrane efflux proteins (OEP) 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
CheY-like Protein kinase-like (PK-like) 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Nucleotidyltransferase TGS-like 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
GAF domain-like GAF domain-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Inosine monophosphate dehydrogenase (IMPDH) NAD(P)-binding Rossmann-fold domains 11
4Fe-4S ferredoxins HydA/Nqo6-like 11
Translation proteins ThrRS/AlaRS common domain 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Translation proteins "Winged helix" DNA-binding domain 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 11
Thioredoxin-like Nqo1C-terminal domain-like 11
Phoshotransferase/anion transport protein Phosphoenolpyruvate/pyruvate domain 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Nqo1C-terminal domain-like Nucleotide-binding domain 11
post-HMGL domain-like Single hybrid motif 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
CheC-like Surface presentation of antigens (SPOA) 11
C-terminal domain of transcriptional repressors C-terminal domain of transcriptional repressors 11
NAD(P)-binding Rossmann-fold domains ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Cation efflux protein cytoplasmic domain-like Nitrogenase accessory factor-like 11
Rubredoxin-like Superoxide reductase-like 11
Molybdenum cofactor biosynthesis proteins Periplasmic binding protein-like II 11
LysM domain LysM domain 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
MoeA N-terminal region -like Periplasmic binding protein-like II 11
FAD/NAD-linked reductases, dimerisation (C-terminal) domain Rhodanese/Cell cycle control phosphatase 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Thioredoxin-like Nqo1 FMN-binding domain-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Acyl-CoA N-acyltransferases (Nat) Arginase/deacetylase 11
Flavoproteins 4Fe-4S ferredoxins 11
DPP6 N-terminal domain-like alpha/beta-Hydrolases 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Rudiment single hybrid motif N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Nucleic acid-binding proteins beta-lactamase/transpeptidase-like 11
Sec-C motif Creatinase/aminopeptidase 11
2Fe-2S ferredoxin-like FAD/NAD(P)-binding domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 11
PRTase-like PRTase-like 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
TPR-like Homeodomain-like 11
Periplasmic binding protein-like II Nucleotide cyclase 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
MCP/YpsA-like PYP-like sensor domain (PAS domain) 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Carbamate kinase-like PUA domain-like 11
UDP-Glycosyltransferase/glycogen phosphorylase HAD-like 11
TGS-like ThrRS/AlaRS common domain 11
Translation proteins PRC-barrel domain 11
PTS system IIB component-like Phosphoenolpyruvate/pyruvate domain 11
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
HAMP domain-like PP2C-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
TSP type-3 repeat OmpA-like 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Phoshotransferase/anion transport protein Phosphohistidine domain 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
PurS-like PurM C-terminal domain-like 11
PUA domain-like alpha/beta knot 11
DHH phosphoesterases Poly A polymerase C-terminal region-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
E set domains Glycosyl hydrolase domain 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Sensory domain-like Nucleotide cyclase 11
Lysozyme-like PGBD-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
FwdE-like Molybdenum cofactor biosynthesis proteins 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
RuvA domain 2-like JAB1/MPN domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
CBS-domain pair Poly A polymerase C-terminal region-like 11
NTF2-like Sec-C motif 11
EspE N-terminal domain-like cAMP-binding domain-like 11
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 11
Zn-dependent exopeptidases Zn-dependent exopeptidases 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Ribulose-phoshate binding barrel Ribulose-phoshate binding barrel 11
Periplasmic binding protein-like II ACT-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Metallo-hydrolase/oxidoreductase Rhodanese/Cell cycle control phosphatase 11
Periplasmic binding protein-like II GlnB-like 11
CBS-domain pair ACT-like 11
TGS-like Class II aaRS ABD-related 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Phoshotransferase/anion transport protein HPr-like 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
PTS system IIB component-like HPr-like 11
FMN-linked oxidoreductases Nucleotide-binding domain 11
PHP domain-like RNase III domain-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
TPR-like GAF domain-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
HPr-like Phosphoenolpyruvate/pyruvate domain 11
TGS-like ACT-like 11
ACP-like Thioesterase/thiol ester dehydrase-isomerase 11
vWA-like TPR-like 11
Translation proteins Translation proteins 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
TPR-like Pili subunits 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Sensory domain-like CheY-like 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
Cation efflux protein transmembrane domain-like Nitrogenase accessory factor-like 11
Class II aaRS and biotin synthetases C-terminal domain of ProRS 11
FKBP-like beta and beta-prime subunits of DNA dependent RNA-polymerase 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Ribosomal protein L6 Ribosomal protein L6 11
GspK insert domain-like RuvA domain 2-like 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 11
FliG FliG 11
alpha/beta-Hydrolases TerB-like 11

Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes · Domain combination pairs ]