SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Lactococcus lactis subsp. cremoris MG1363

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

446 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2311
Calcium ATPase, transduction domain A HAD-like 113
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 112
HAD-like Calcium ATPase, transmembrane domain M 113
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 113
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 113
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 102
Homeodomain-like SIS domain 91
Actin-like ATPase domain Actin-like ATPase domain 84
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 73
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 64
P-loop containing nucleoside triphosphate hydrolases Translation proteins 65
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 63
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 61
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 62
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 61
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 61
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 61
CheY-like C-terminal effector domain of the bipartite response regulators 51
GroES-like NAD(P)-binding Rossmann-fold domains 51
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 53
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 43
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 41
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 42
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 41
Homeodomain-like Homeodomain-like 44
PreATP-grasp domain Rudiment single hybrid motif 42
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 41
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 41
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 41
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 43
Nucleic acid-binding proteins Nucleic acid-binding proteins 44
Translation proteins EF-G C-terminal domain-like 43
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 41
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 41
Nucleic acid-binding proteins RuvA domain 2-like 33
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 33
Lysozyme-like beta-lactamase/transpeptidase-like 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 32
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 32
(Trans)glycosidases Glycosyl hydrolase domain 33
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 32
LysM domain LysM domain 32
MetI-like Periplasmic binding protein-like II 33
Thiolase-like Thiolase-like 31
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 31
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 33
cAMP-binding domain-like "Winged helix" DNA-binding domain 31
Galactose mutarotase-like Six-hairpin glycosidases 31
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 31
TrpR-like Homeodomain-like 31
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Alpha-L RNA-binding motif Pseudouridine synthase 31
(Trans)glycosidases Cyclophilin-like 21
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 21
L30e-like alpha/beta knot 21
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 21
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Phoshotransferase/anion transport protein PTS system IIB component-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
PurM N-terminal domain-like PurM C-terminal domain-like 22
P-loop containing nucleoside triphosphate hydrolases MOP-like 22
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 21
"Winged helix" DNA-binding domain C-terminal domain of arginine repressor 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 22
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 21
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 22
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 21
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 21
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 21
Aspartate/glutamate racemase Aspartate/glutamate racemase 21
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 22
Enolase N-terminal domain-like Enolase C-terminal domain-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 22
E set domains (Trans)glycosidases 22
Glucose permease domain IIB Duplicated hybrid motif 21
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 22
Nucleic acid-binding proteins Ribonuclease H-like 22
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 22
PLP-binding barrel Alanine racemase C-terminal domain-like 21
MFS general substrate transporter MFS general substrate transporter 21
FAD/NAD(P)-binding domain Rhodanese/Cell cycle control phosphatase 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
FAD/NAD-linked reductases, dimerisation (C-terminal) domain Rhodanese/Cell cycle control phosphatase 22
"Winged helix" DNA-binding domain Chorismate lyase-like 21
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
PTS-regulatory domain, PRD Phoshotransferase/anion transport protein 22
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 22
ACT-like ACT-like 22
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
C-terminal domain of transcriptional repressors C-terminal domain of transcriptional repressors 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
PreATP-grasp domain Single hybrid motif 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Resolvase-like Homeodomain-like 11
Thioredoxin-like Thioredoxin-like 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
HD-domain/PDEase-like ACT-like 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
beta-lactamase/transpeptidase-like Penicillin-binding protein 2x (pbp-2x), c-terminal domain 11
"Winged helix" DNA-binding domain C-terminal domain of transcriptional repressors 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Periplasmic binding protein-like II Periplasmic binding protein-like II 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
NAD-binding domain of HMG-CoA reductase Substrate-binding domain of HMG-CoA reductase 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
PreATP-grasp domain post-HMGL domain-like 11
Rudiment single hybrid motif Single hybrid motif 11
THUMP domain-like Adenine nucleotide alpha hydrolases-like 11
Ribulose-phoshate binding barrel Nucleotidyltransferase 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain Galactose-binding domain-like 11
Carbamate kinase-like ACT-like 11
DNA repair protein MutS, domain III SMR domain-like 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
PRTase-like PRTase-like 11
TGS-like ACT-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
HprK N-terminal domain-like CBS-domain pair 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 11
Aldolase Single hybrid motif 11
Chaperone J-domain HSP40/DnaJ peptide-binding domain 11
PUA domain-like alpha/beta knot 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 11
RuvA domain 2-like RuvA domain 2-like 11
Nucleotidyltransferase TGS-like 11
Penicillin binding protein dimerisation domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
RuvA domain 2-like BRCT domain 11
GroEL-intermediate domain like GroEL apical domain-like 11
DNA methylase specificity domain DNA methylase specificity domain 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 11
Aldolase post-HMGL domain-like 11
HD-domain/PDEase-like Nucleotidyltransferase 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Phospholipase D/nuclease Phospholipase D/nuclease 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
ALDH-like Dehydroquinate synthase-like 11
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain alpha/beta-Hydrolases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
Ribonuclease H-like P-loop containing nucleoside triphosphate hydrolases 11
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 11
Tex N-terminal region-like RuvA domain 2-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Cna protein B-type domain Cna protein B-type domain 11
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 11
Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain 11
Bacterial adhesins Bacterial adhesins 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
DNA clamp DNA clamp 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Rudiment single hybrid motif Aldolase 11
FKBP-like Triger factor/SurA peptide-binding domain-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
HisI-like all-alpha NTP pyrophosphatases 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
post-HMGL domain-like Single hybrid motif 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Ribonuclease H-like RuvA domain 2-like 11
YrdC/RibB RibA-like 11
P-loop containing nucleoside triphosphate hydrolases LysM domain 11
Single hybrid motif CoA-dependent acyltransferases 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
"Winged helix" DNA-binding domain HRDC-like 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Thioredoxin-like 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
alpha-helical ferredoxin Nucleotide-binding domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Tex N-terminal region-like Ribonuclease H-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
TGS-like Class II aaRS ABD-related 11
Thiamin diphosphate-binding fold (THDP-binding) 4Fe-4S ferredoxins 11
Nucleic acid-binding proteins GAD domain-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
"Winged helix" DNA-binding domain GAF domain-like 11
Formyltransferase FMT C-terminal domain-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Translation proteins Translation proteins 11
Regulatory protein AraC Homeodomain-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
HprK N-terminal domain-like PEP carboxykinase-like 11
PTS system IIB component-like PTS system IIB component-like 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
GIY-YIG endonuclease RuvA domain 2-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Fibronectin type III Carbohydrate binding domain 11
PTS-regulatory domain, PRD PTS system IIB component-like 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
(Trans)glycosidases Carbohydrate binding domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Translation proteins PRC-barrel domain 11
(Trans)glycosidases Fibronectin type III 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
Obg GTP-binding protein N-terminal domain Obg GTP-binding protein C-terminal domain 11
"Winged helix" DNA-binding domain Iron-dependent repressor protein, dimerization domain 11
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK Tetrahydrobiopterin biosynthesis enzymes-like 11
"Winged helix" DNA-binding domain NAD(P)-binding Rossmann-fold domains 11
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
lambda repressor-like DNA-binding domains LexA/Signal peptidase 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
"Winged helix" DNA-binding domain TrkA C-terminal domain-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Class II aaRS and biotin synthetases SufE/NifU 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Nucleotidylyl transferase P-loop containing nucleoside triphosphate hydrolases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
Translation proteins ThrRS/AlaRS common domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
PDZ domain-like Ribosomal protein S5 domain 2-like 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Ribosomal protein L6 Ribosomal protein L6 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Trypsin-like serine proteases PDZ domain-like 11
"Winged helix" DNA-binding domain Phoshotransferase/anion transport protein 11
PIN domain-like Ribonuclease H-like 11
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Class II aaRS and biotin synthetases Translation proteins 11
Cystatin/monellin Cystatin/monellin 11
Apolipoprotein A-I Lysozyme-like 11
Glutathione synthetase ATP-binding domain-like Aldolase 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
HprK N-terminal domain-like Thioesterase/thiol ester dehydrase-isomerase 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
TPR-like TPR-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Nucleotidylyl transferase tRNA-binding arm 11
Concanavalin A-like lectins/glucanases Cna protein B-type domain 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
(Trans)glycosidases LysM domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
Nucleic acid-binding proteins BRCT domain 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
TK C-terminal domain-like 4Fe-4S ferredoxins 11
Serine metabolism enzymes domain ACT-like 11
Nucleotidyltransferase ACT-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
E set domains Glycosyl hydrolase domain 11
L domain-like Metalloproteases ("zincins"), catalytic domain 11
CarD-like TRCF domain-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
MalF N-terminal region-like MetI-like 11
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 11
TGS-like Class II aaRS and biotin synthetases 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
RNase III domain-like dsRNA-binding domain-like 11
"Winged helix" DNA-binding domain PLP-dependent transferases 11
Rudiment single hybrid motif post-HMGL domain-like 11
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 11
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 11
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
PheT/TilS domain Putative DNA-binding domain 11
Major capsid protein gp5 Invasin/intimin cell-adhesion fragments 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Nucleic acid-binding proteins PheT/TilS domain 11
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
"Winged helix" DNA-binding domain PTS-regulatory domain, PRD 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 11
HD-domain/PDEase-like TGS-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Cell wall binding repeat Cysteine proteinases 11
Hsp33 domain HSP33 redox switch-like 11
DeoB insert domain-like Alkaline phosphatase-like 11
CBS-domain pair FAD-binding/transporter-associated domain-like 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
Zinc beta-ribbon DNA primase core 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
CBS-domain pair Thioesterase/thiol ester dehydrase-isomerase 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 11
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
lambda repressor-like DNA-binding domains TPR-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 4Fe-4S ferredoxins 11
Ribonuclease H-like DNA/RNA polymerases 11
PIN domain-like DNA/RNA polymerases 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
E set domains Six-hairpin glycosidases 11
HMA, heavy metal-associated domain HAD-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
PreATP-grasp domain Aldolase 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Glutathione synthetase ATP-binding domain-like post-HMGL domain-like 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
Periplasmic binding protein-like II ACT-like 11
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
P-loop containing nucleoside triphosphate hydrolases Obg GTP-binding protein C-terminal domain 11
PTS system fructose IIA component-like PTS IIb component 11
Clc chloride channel TrkA C-terminal domain-like 11
UROD/MetE-like UROD/MetE-like 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
TGS-like ThrRS/AlaRS common domain 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
DhaL-like DAK1/DegV-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
"Winged helix" DNA-binding domain PRTase-like 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
DNA-glycosylase Nudix 11
Single hybrid motif Single hybrid motif 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Galactose-binding domain-like SGNH hydrolase 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Class II aaRS and biotin synthetases GAD domain-like 11
PreATP-grasp domain PreATP-grasp domain 11

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