SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Maricaulis maris MCS10

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

587 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 3416
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2011
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 158
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 146
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 1410
Thioredoxin-like GST C-terminal domain-like 142
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1410
Homodimeric domain of signal transducing histidine kinase CheY-like 147
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 125
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 123
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 123
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 111
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 104
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 104
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 104
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 104
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 102
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 104
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 93
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 95
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 92
Actin-like ATPase domain Actin-like ATPase domain 94
CheY-like C-terminal effector domain of the bipartite response regulators 81
DPP6 N-terminal domain-like alpha/beta-Hydrolases 82
GroES-like NAD(P)-binding Rossmann-fold domains 82
P-loop containing nucleoside triphosphate hydrolases Translation proteins 76
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 65
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 63
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 62
PreATP-grasp domain Rudiment single hybrid motif 63
Thiolase-like Thiolase-like 61
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 63
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Homeodomain-like Homeodomain-like 65
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 62
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 63
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
CheY-like P-loop containing nucleoside triphosphate hydrolases 52
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 54
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 51
Nucleotide cyclase EAL domain-like 54
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 53
PYP-like sensor domain (PAS domain) CheY-like 54
TPR-like TPR-like 54
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 44
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 42
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 41
TPR-like P-loop containing nucleoside triphosphate hydrolases 42
Ribosomal protein S5 domain 2-like P-loop containing nucleoside triphosphate hydrolases 44
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 43
HCP-like HCP-like 43
Lysozyme-like beta-lactamase/transpeptidase-like 43
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 41
PurM N-terminal domain-like PurM C-terminal domain-like 42
CheY-like Homeodomain-like 41
PDZ domain-like PDZ domain-like 43
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 44
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 41
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 42
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 42
Nucleic acid-binding proteins Nucleic acid-binding proteins 44
ACT-like ACT-like 44
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 42
PLP-binding barrel Alanine racemase C-terminal domain-like 33
TrkA C-terminal domain-like TrkA C-terminal domain-like 32
Rudiment single hybrid motif Single hybrid motif 32
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 31
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 31
CheY-like Nucleotide cyclase 32
Translation proteins EF-G C-terminal domain-like 33
GAF domain-like Homodimeric domain of signal transducing histidine kinase 33
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 33
PreATP-grasp domain Single hybrid motif 32
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Pentapeptide repeat-like Pentapeptide repeat-like 32
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 33
lambda repressor-like DNA-binding domains PYP-like sensor domain (PAS domain) 31
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 33
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 32
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 32
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 31
Alpha-L RNA-binding motif Pseudouridine synthase 32
Glutathione synthetase ATP-binding domain-like Single hybrid motif 32
Single hybrid motif CoA-dependent acyltransferases 32
Trypsin-like serine proteases PDZ domain-like 32
ClpP/crotonase ClpP/crotonase 32
FKBP-like Triger factor/SurA peptide-binding domain-like 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Cadherin-like beta-Roll 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Cadherin-like Cadherin-like 22
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 22
Cytochrome c Cytochrome c 22
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 21
GroES-like GroES-like 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
FAD/NAD(P)-binding domain HI0933 insert domain-like 21
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 22
cAMP-binding domain-like "Winged helix" DNA-binding domain 21
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 22
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 22
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 21
Class I glutamine amidotransferase-like Homeodomain-like 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 21
PGBD-like HCP-like 22
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 22
GAF domain-like PYP-like sensor domain (PAS domain) 22
P-loop containing nucleoside triphosphate hydrolases Glucocorticoid receptor-like (DNA-binding domain) 22
TPR-like Nucleotide cyclase 22
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Carbamate kinase-like PUA domain-like 21
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Nucleic acid-binding proteins RuvA domain 2-like 22
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 22
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 22
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 21
PA domain Zn-dependent exopeptidases 21
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 22
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 21
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 21
CBS-domain pair FAD-binding/transporter-associated domain-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
HAD-like Calcium ATPase, transmembrane domain M 22
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
(Trans)glycosidases Glycosyl hydrolase domain 22
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Calcium ATPase, transduction domain A HAD-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Cupredoxins Cupredoxins 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
MFS general substrate transporter MFS general substrate transporter 21
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Nqo1 middle domain-like Nqo1C-terminal domain-like 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 22
Carboxypeptidase regulatory domain-like Porins 22
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 22
Nucleotidyltransferase ACT-like 22
ISP domain Bet v1-like 21
alpha-helical ferredoxin Nucleotide-binding domain 22
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 22
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Zn-dependent exopeptidases Class I glutamine amidotransferase-like 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
Carbamate kinase-like ACT-like 22
Periplasmic binding protein-like II MetI-like 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Heme-dependent peroxidases Heme-dependent peroxidases 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Hsp33 domain HSP33 redox switch-like 11
CheW-like CheY-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Pectin lyase-like Pectin lyase-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Nudix "Winged helix" DNA-binding domain 11
Cadherin-like Metalloproteases ("zincins"), catalytic domain 11
alpha-helical ferredoxin 4Fe-4S ferredoxins 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Nucleotidyltransferase TGS-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
YjeF N-terminal domain-like Ribokinase-like 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
Formyltransferase FMT C-terminal domain-like 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
YrdC/RibB RibA-like 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
LysM domain Duplicated hybrid motif 11
Zinc beta-ribbon DNA primase core 11
Periplasmic binding protein-like II ACT-like 11
DNA clamp DNA clamp 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
HlyD-like secretion proteins HlyD-like secretion proteins 11
Phospholipase D/nuclease Phospholipase D/nuclease 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
CarD-like TRCF domain-like 11
Ferritin-like Calcium ATPase, transduction domain A 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
HRDC-like HRDC-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
RuvA domain 2-like JAB1/MPN domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Chorismate mutase II ACT-like 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
Carbamate kinase-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
Carbamate kinase-like NAD(P)-binding Rossmann-fold domains 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Periplasmic binding protein-like II Lysozyme-like 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
TPR-like EAL domain-like 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Nucleic acid-binding proteins GAD domain-like 11
HD-domain/PDEase-like TGS-like 11
Oligoxyloglucan reducing end-specific cellobiohydrolase Oligoxyloglucan reducing end-specific cellobiohydrolase 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Nucleotide-diphospho-sugar transferases Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Aldolase AFP III-like domain 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
Ribonuclease H-like HRDC-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Carbamate kinase-like PLP-binding barrel 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
HAMP domain-like Nucleotide cyclase 11
PYP-like sensor domain (PAS domain) Nucleotide cyclase 11
Carbamate kinase-like Alanine racemase C-terminal domain-like 11
TGS-like ACT-like 11
Glutathione synthetase ATP-binding domain-like post-HMGL domain-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Toll/Interleukin receptor TIR domain TPR-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
MgtE N-terminal domain-like CBS-domain pair 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
SIS domain CBS-domain pair 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Homeodomain-like Ribonuclease H-like 11
Class II aaRS and biotin synthetases Translation proteins 11
cAMP-binding domain-like FabD/lysophospholipase-like 11
4Fe-4S ferredoxins ADC-like 11
NHL repeat Metallo-dependent hydrolases 11
Lysozyme-like PGBD-like 11
Translation proteins ThrRS/AlaRS common domain 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Acid proteases Acid proteases 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
PGBD-like L,D-transpeptidase catalytic domain-like 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
TGS-like ThrRS/AlaRS common domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
PreATP-grasp domain PreATP-grasp domain 11
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases DNA ligase/mRNA capping enzyme, catalytic domain 11
FMN-binding split barrel UbiD C-terminal domain-like 11
alpha-helical ferredoxin ARM repeat 11
L30e-like alpha/beta knot 11
"Winged helix" DNA-binding domain Chorismate lyase-like 11
alpha/beta-Hydrolases OsmC-like 11
"Winged helix" DNA-binding domain NosL/MerB-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Single hybrid motif Thiamin diphosphate-binding fold (THDP-binding) 11
Metallo-dependent phosphatases DNA ligase/mRNA capping enzyme, catalytic domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
CheY-like Methylesterase CheB, C-terminal domain 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Regulatory protein AraC Homeodomain-like 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
Pili subunits GspK insert domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
GspK insert domain-like GspK insert domain-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
TPR-like TolA/TonB C-terminal domain 11
PDZ domain-like ClpP/crotonase 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Ferritin-like Calcium ATPase, transmembrane domain M 11
Integrin alpha N-terminal domain Integrin alpha N-terminal domain 11
Inosine monophosphate dehydrogenase (IMPDH) Nitrite and sulphite reductase 4Fe-4S domain-like 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
Metallo-hydrolase/oxidoreductase SCP-like 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Dihydropteroate synthetase-like Methionine synthase domain 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Periplasmic binding protein-like II GlnB-like 11
TGS-like Class II aaRS ABD-related 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
DPP6 N-terminal domain-like Metallo-dependent hydrolases 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
FliG FliG 11
Ribonuclease H-like DNA/RNA polymerases 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III Thiamin diphosphate-binding fold (THDP-binding) 11
PheT/TilS domain Putative DNA-binding domain 11
MetI-like MetI-like 11
L21p-like Rad51 N-terminal domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
CBS-domain pair ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
P-loop containing nucleoside triphosphate hydrolases MOP-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Aldolase 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Zn-dependent exopeptidases Fibronectin type III 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Metalloproteases ("zincins"), catalytic domain beta-Roll 11
C-terminal effector domain of the bipartite response regulators TPR-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
RuvA domain 2-like BRCT domain 11
Translation proteins PRC-barrel domain 11
Nucleotidyltransferase Nucleotidyltransferase 11
RmlC-like cupins Homeodomain-like 11
ACT-like PLP-binding barrel 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
HD-domain/PDEase-like Nucleotidyltransferase 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
PRTase-like PRTase-like 11
CBS-domain pair MgtE membrane domain-like 11
HMA, heavy metal-associated domain HAD-like 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
2Fe-2S ferredoxin-like ADC-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Nucleotide-diphospho-sugar transferases S-adenosyl-L-methionine-dependent methyltransferases 11
HD-domain/PDEase-like ACT-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
GAF domain-like Phosphohistidine domain 11
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Nucleotide-diphospho-sugar transferases UDP-Glycosyltransferase/glycogen phosphorylase 11
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
ALDH-like Ribosomal protein S5 domain 2-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 11
DNA-glycosylase Nudix 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
YebC-like PFL-like glycyl radical enzymes 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
GIY-YIG endonuclease RuvA domain 2-like 11
Resolvase-like KorB DNA-binding domain-like 11
beta-Roll beta-Roll 11
Translation proteins Translation proteins 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Histidine-containing phosphotransfer domain, HPT domain CheY-like 11
Nucleotidylyl transferase tRNA-binding arm 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
PilZ domain-like PilZ domain-like 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Nucleotide-binding domain 4Fe-4S ferredoxins 11
CBS-domain pair CheY-like 11
ACT-like Alanine racemase C-terminal domain-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
HAMP domain-like EAL domain-like 11
Aldolase post-HMGL domain-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Nucleotidyltransferase substrate binding subunit/domain Poly A polymerase C-terminal region-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
CheW-like CheW-like 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
PUA domain-like alpha/beta knot 11
Rudiment single hybrid motif post-HMGL domain-like 11
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Dimeric alpha+beta barrel Acyl-CoA N-acyltransferases (Nat) 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
NHL repeat DPP6 N-terminal domain-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Ferritin-like HAD-like 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
Globin-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Aldolase Single hybrid motif 11
Chorismate mutase II Periplasmic binding protein-like II 11
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 11
CheY-like CheY-like 11
Nucleotide-binding domain Nucleotide-binding domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Single hybrid motif TK C-terminal domain-like 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
Trigger factor ribosome-binding domain FKBP-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Thioredoxin-like TPR-like 11
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
DNA methylase specificity domain DNA methylase specificity domain 11
Nucleic acid-binding proteins PheT/TilS domain 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
HisI-like all-alpha NTP pyrophosphatases 11
Trypsin-like serine proteases Autotransporter 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
Rudiment single hybrid motif Aldolase 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 11
Resolvase-like Homeodomain-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
dUTPase-like dUTPase-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
CheC-like Surface presentation of antigens (SPOA) 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
PIN domain-like Ribonuclease H-like 11
PPK N-terminal domain-like PHP14-like 11
Macro domain-like Zn-dependent exopeptidases 11
Nucleotidylyl transferase Riboflavin kinase-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
PreATP-grasp domain Aldolase 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
gamma-Crystallin-like gamma-Crystallin-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
YlxR-like L30e-like 11
CBS-domain pair Homodimeric domain of signal transducing histidine kinase 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
Single hybrid motif Single hybrid motif 11
PreATP-grasp domain post-HMGL domain-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
RNase III domain-like dsRNA-binding domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Acyl-CoA N-acyltransferases (Nat) Carbon-nitrogen hydrolase 11
E set domains Six-hairpin glycosidases 11
Bacterial muramidases Lysozyme-like 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
TerB-like Chaperone J-domain 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
TGS-like Class II aaRS and biotin synthetases 11
DPP6 N-terminal domain-like Composite domain of metallo-dependent hydrolases 11
Class II aaRS and biotin synthetases GAD domain-like 11
PYP-like sensor domain (PAS domain) EAL domain-like 11
Pili subunits Pili subunits 11
post-HMGL domain-like Single hybrid motif 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III TK C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
P-loop containing nucleoside triphosphate hydrolases Metallo-dependent phosphatases 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
"Winged helix" DNA-binding domain GAF domain-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 11
GroEL-intermediate domain like GroEL apical domain-like 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Poly A polymerase C-terminal region-like ACT-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Nucleic acid-binding proteins BRCT domain 11
Barwin-like endoglucanases Sporulation related repeat 11
FAD/NAD(P)-binding domain FMN-linked oxidoreductases 11
NHL repeat Composite domain of metallo-dependent hydrolases 11
PHP14-like Phospholipase D/nuclease 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
OMPA-like OmpA-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
PreATP-grasp domain Methylglyoxal synthase-like 11
FAD-linked oxidoreductase ALDH-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
Ribosomal protein L6 Ribosomal protein L6 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
PIN domain-like DNA/RNA polymerases 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Creatinase/prolidase N-terminal domain Creatinase/prolidase N-terminal domain 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
E set domains alpha/beta-Hydrolases 11
Phase 1 flagellin NHL repeat 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
GAF domain-like CheY-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11

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