SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Legionella pneumophila str. Corby

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

565 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 1911
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 141
Nucleotide cyclase EAL domain-like 128
PYP-like sensor domain (PAS domain) Nucleotide cyclase 1010
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 107
Actin-like ATPase domain Actin-like ATPase domain 92
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 94
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 94
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 94
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 94
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 94
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 94
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 93
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 94
Calcium ATPase, transduction domain A HAD-like 83
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 83
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 82
Thiolase-like Thiolase-like 82
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 82
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 84
HAD-like Calcium ATPase, transmembrane domain M 83
PYP-like sensor domain (PAS domain) EAL domain-like 77
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 73
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 74
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 73
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
P-loop containing nucleoside triphosphate hydrolases Translation proteins 65
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 62
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 54
GroES-like NAD(P)-binding Rossmann-fold domains 51
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 53
HCP-like HCP-like 53
PreATP-grasp domain Rudiment single hybrid motif 52
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 55
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 53
Thioredoxin-like GST C-terminal domain-like 51
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 54
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 52
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 55
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 42
GAF domain-like Nucleotide cyclase 44
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 41
CheY-like PYP-like sensor domain (PAS domain) 44
lambda repressor-like DNA-binding domains LexA/Signal peptidase 41
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 41
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 41
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 44
PurM N-terminal domain-like PurM C-terminal domain-like 42
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 41
CBS-domain pair FAD-binding/transporter-associated domain-like 31
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 32
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 32
HD-domain/PDEase-like ACT-like 32
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Single hybrid motif CoA-dependent acyltransferases 32
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
Alpha-L RNA-binding motif Pseudouridine synthase 31
Nucleotidyltransferase HD-domain/PDEase-like 32
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 33
Ankyrin repeat Ankyrin repeat 33
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
Nucleotidyltransferase ACT-like 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Nucleic acid-binding proteins RuvA domain 2-like 33
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
HMA, heavy metal-associated domain HAD-like 31
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 31
Homodimeric domain of signal transducing histidine kinase CheY-like 33
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 32
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 32
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 31
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
FKBP-like Triger factor/SurA peptide-binding domain-like 33
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 31
CheY-like C-terminal effector domain of the bipartite response regulators 31
CheY-like P-loop containing nucleoside triphosphate hydrolases 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 33
TPR-like S-adenosyl-L-methionine-dependent methyltransferases 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Translation proteins EF-G C-terminal domain-like 33
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 33
CheY-like Homeodomain-like 31
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 32
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 33
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 22
Trypsin-like serine proteases PDZ domain-like 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Aldolase AFP III-like domain 21
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
NAD(P)-binding Rossmann-fold domains ClpP/crotonase 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
TPR-like TPR-like 22
ACP-like NAD(P)-binding Rossmann-fold domains 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Thiolase-like NAD(P)-binding Rossmann-fold domains 22
PDZ domain-like PDZ domain-like 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
P-loop containing nucleoside triphosphate hydrolases Glucocorticoid receptor-like (DNA-binding domain) 22
Enolase N-terminal domain-like Enolase C-terminal domain-like 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 21
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 22
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
Nucleotidyltransferase TGS-like 21
Heme-dependent peroxidases Heme-dependent peroxidases 21
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 21
Cupredoxins Cupredoxins 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
Homeodomain-like Ribonuclease H-like 21
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
Thiolase-like ACP-like 22
Nucleotidyltransferase Acyl-CoA N-acyltransferases (Nat) 22
6-phosphogluconate dehydrogenase C-terminal domain-like ClpP/crotonase 22
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 22
PYP-like sensor domain (PAS domain) GAF domain-like 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
HlyD-like secretion proteins HlyD-like secretion proteins 21
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
ClpP/crotonase ClpP/crotonase 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
ACP-like ACP-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Phospholipase D/nuclease Phospholipase D/nuclease 22
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 22
Lysozyme-like LysM domain 22
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 22
Cytochrome c Cytochrome c 22
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 21
Translation proteins ThrRS/AlaRS common domain 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
LysM domain LysM domain 22
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 21
HD-domain/PDEase-like TGS-like 21
TGS-like ACT-like 21
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 21
P-loop containing nucleoside triphosphate hydrolases MOP-like 21
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 21
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
PLP-binding barrel Alanine racemase C-terminal domain-like 22
Lysozyme-like beta-lactamase/transpeptidase-like 22
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 22
RmlC-like cupins Homeodomain-like 11
F-box domain Ankyrin repeat 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
ACP-like CoA-dependent acyltransferases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
Tex N-terminal region-like RuvA domain 2-like 11
FKBP-like FKBP-like 11
ACP-like FabD/lysophospholipase-like 11
beta-Roll beta-Roll 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
ACT-like ACT-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Amine oxidase N-terminal region Amine oxidase N-terminal region 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Ribonuclease H-like DNA/RNA polymerases 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
ACT-like PLP-binding barrel 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Nucleotidylyl transferase Riboflavin kinase-like 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Zn-dependent exopeptidases LysM domain 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
Ribonuclease H-like RuvA domain 2-like 11
Class II aaRS and biotin synthetases Translation proteins 11
GAF domain-like Phosphohistidine domain 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Dimeric alpha+beta barrel Dimeric alpha+beta barrel 11
Amine oxidase N-terminal region Amine oxidase catalytic domain 11
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 11
Myosin rod fragments Duplicated hybrid motif 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
CoA-dependent acyltransferases CoA-dependent acyltransferases 11
Periplasmic binding protein-like I EAL domain-like 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Hsp33 domain HSP33 redox switch-like 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Periplasmic binding protein-like I PYP-like sensor domain (PAS domain) 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Barwin-like endoglucanases Sporulation related repeat 11
Carbamate kinase-like ACT-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Sensory domain-like Nucleotide cyclase 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
PIN domain-like DNA/RNA polymerases 11
Periplasmic binding protein-like I Periplasmic binding protein-like I 11
Class II aaRS and biotin synthetases GAD domain-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Homeodomain-like Homeodomain-like 11
PPK N-terminal domain-like PHP14-like 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Isocitrate/Isopropylmalate dehydrogenase-like RraA-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
PIN domain-like Ribonuclease H-like 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
GroEL-intermediate domain like GroEL apical domain-like 11
F-box domain Protein kinase-like (PK-like) 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 11
Acetyl-CoA synthetase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Trigger factor ribosome-binding domain FKBP-like 11
cAMP-binding domain-like cAMP-binding domain-like 11
ISP domain Bet v1-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
YrdC/RibB RibA-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
FAD/NAD(P)-binding domain cAMP-binding domain-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
GAF domain-like GAF domain-like 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
NAD-binding domain of HMG-CoA reductase Substrate-binding domain of HMG-CoA reductase 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
Aldolase post-HMGL domain-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
post-HMGL domain-like Single hybrid motif 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Zinc beta-ribbon Zinc beta-ribbon 11
Mss4-like Peptide methionine sulfoxide reductase 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
PHP domain-like Nucleic acid-binding proteins 11
Periplasmic binding protein-like II GlnB-like 11
Thiolase-like alpha/beta-Hydrolases 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Acetyl-CoA synthetase-like NAD(P)-binding Rossmann-fold domains 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Putative DNA-binding domain Antibiotic binding domain of TipA-like multidrug resistance regulators 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Homodimeric domain of signal transducing histidine kinase Homodimeric domain of signal transducing histidine kinase 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
CheY-like Histidine-containing phosphotransfer domain, HPT domain 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Thioesterase/thiol ester dehydrase-isomerase Isocitrate/Isopropylmalate dehydrogenase-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Concanavalin A-like lectins/glucanases Fibronectin type III 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Acetyl-CoA synthetase-like alpha/beta-Hydrolases 11
DNA methylase specificity domain DNA methylase specificity domain 11
CarD-like TRCF domain-like 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
vWA-like beta-Roll 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
MetI-like MetI-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Rudiment single hybrid motif Single hybrid motif 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
CBS-domain pair PLP-dependent transferases 11
ACT-like Alanine racemase C-terminal domain-like 11
TGS-like ThrRS/AlaRS common domain 11
Zinc beta-ribbon DNA primase core 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Periplasmic binding protein-like I Nucleotide cyclase 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Nucleic acid-binding proteins GAD domain-like 11
Ribonuclease H-like P-loop containing nucleoside triphosphate hydrolases 11
Carbamate kinase-like PLP-binding barrel 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Cupredoxins Cytochrome c 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
NTF2-like Sec-C motif 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Putative DNA-binding domain Translation proteins 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Bacterial muramidases Lysozyme-like 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
L30e-like alpha/beta knot 11
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
ACP-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Pseudo ankyrin repeat-like Pseudo ankyrin repeat-like 11
CheY-like CheY-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Acetyl-CoA synthetase-like ACP-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
SET domain Ankyrin repeat 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
PreATP-grasp domain PreATP-grasp domain 11
Outer membrane efflux proteins (OEP) Sporulation related repeat 11
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III Thiamin diphosphate-binding fold (THDP-binding) 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Nucleotidyltransferase PAP/OAS1 substrate-binding domain 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Sec7 domain RalF, C-terminal domain 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
PreATP-grasp domain Single hybrid motif 11
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III TK C-terminal domain-like 11
YjeF N-terminal domain-like Ribokinase-like 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
Translation proteins PRC-barrel domain 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 11
PRTase-like PRTase-like 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
TerB-like Chaperone J-domain 11
TGS-like Class II aaRS ABD-related 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
DPP6 N-terminal domain-like alpha/beta-Hydrolases 11
DNA-glycosylase Nudix 11
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Thiolase-like CoA-dependent acyltransferases 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
FliG FliG 11
Fic-like Ankyrin repeat 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
HAD-like Ribosomal protein S5 domain 2-like 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
PHP14-like Phospholipase D/nuclease 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Nucleotidylyl transferase tRNA-binding arm 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Ribokinase-like RmlC-like cupins 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Ferritin-like CoA-dependent acyltransferases 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
CheC-like Surface presentation of antigens (SPOA) 11
Translation proteins Translation proteins 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
Ribokinase-like Thiamin phosphate synthase 11
Nucleic acid-binding proteins BRCT domain 11
DhaL-like DAK1/DegV-like 11
Aldolase Single hybrid motif 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
RNase III domain-like dsRNA-binding domain-like 11
NAD(P)-binding Rossmann-fold domains CoA-dependent acyltransferases 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
DNA primase core DNA primase DnaG, C-terminal domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Acetyl-CoA synthetase-like Thiolase-like 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
Tex N-terminal region-like Ribonuclease H-like 11
vWA-like Quinoprotein alcohol dehydrogenase-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Acetyl-CoA synthetase-like FabD/lysophospholipase-like 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Carbamate kinase-like PUA domain-like 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
HAMP domain-like Nucleotide cyclase 11
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 11
PDZ domain-like ClpP/crotonase 11
SpoIIaa-like cAMP-binding domain-like 11
ADC synthase Class I glutamine amidotransferase-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
RuvA domain 2-like RuvA domain 2-like 11
Class I glutamine amidotransferase-like Class I glutamine amidotransferase-like 11
Pseudouridine synthase PUA domain-like 11
Clavaminate synthase-like S-adenosyl-L-methionine-dependent methyltransferases 11
ClpP/crotonase NfeD domain-like 11
Carbamate kinase-like Alanine racemase C-terminal domain-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
"Winged helix" DNA-binding domain C-terminal domain of arginine repressor 11
PheT/TilS domain Putative DNA-binding domain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Ribonuclease H-like Nucleic acid-binding proteins 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
FMN-binding split barrel UbiD C-terminal domain-like 11
HisI-like all-alpha NTP pyrophosphatases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Ribosomal protein L6 Ribosomal protein L6 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
NAD(P)-binding Rossmann-fold domains alpha/beta-Hydrolases 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
TGS-like Class II aaRS and biotin synthetases 11
Phase 1 flagellin Phase 1 flagellin 11
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 11
DNA clamp DNA clamp 11
CheY-like EAL domain-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
Formyltransferase FMT C-terminal domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
FabD/lysophospholipase-like alpha/beta-Hydrolases 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
FAD-linked oxidoreductase ALDH-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
ACP-like alpha/beta-Hydrolases 11
PUA domain-like alpha/beta knot 11
GAF domain-like EAL domain-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase alpha/beta-Hydrolases 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
PK beta-barrel domain-like PK C-terminal domain-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
DeoB insert domain-like Alkaline phosphatase-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Sporulation related repeat OMPA-like 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Thiolase-like FabD/lysophospholipase-like 11
YajQ-like YajQ-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Pentapeptide repeat-like Pentapeptide repeat-like 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Nucleic acid-binding proteins PheT/TilS domain 11
Single hybrid motif Single hybrid motif 11
Macro domain-like Zn-dependent exopeptidases 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
RuvA domain 2-like BRCT domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
CheY-like Nucleotide cyclase 11

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