SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Coxiella burnetii Dugway 5J108-111

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

466 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 1610
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 93
Actin-like ATPase domain Actin-like ATPase domain 72
Thiolase-like Thiolase-like 71
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 76
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 62
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 64
P-loop containing nucleoside triphosphate hydrolases Translation proteins 65
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 55
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 53
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 54
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 53
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 52
CheY-like C-terminal effector domain of the bipartite response regulators 51
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 53
PYP-like sensor domain (PAS domain) CheY-like 44
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 42
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 44
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 42
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 42
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 43
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 42
Homodimeric domain of signal transducing histidine kinase CheY-like 44
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 42
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 44
Ankyrin repeat Ankyrin repeat 43
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 42
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 42
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 33
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 32
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 31
PreATP-grasp domain Rudiment single hybrid motif 32
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 32
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 33
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 32
HlyD-like secretion proteins HlyD-like secretion proteins 33
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 32
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 31
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 33
PurM N-terminal domain-like PurM C-terminal domain-like 32
Alpha-L RNA-binding motif Pseudouridine synthase 31
S-adenosyl-L-methionine-dependent methyltransferases TPR-like 32
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 31
Translation proteins EF-G C-terminal domain-like 33
MFS general substrate transporter MFS general substrate transporter 32
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Single hybrid motif CoA-dependent acyltransferases 32
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
Nucleotidylyl transferase Ribokinase-like 22
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 22
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
PLP-binding barrel Alanine racemase C-terminal domain-like 21
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 21
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
Enolase N-terminal domain-like Enolase C-terminal domain-like 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
ParB/Sulfiredoxin KorB DNA-binding domain-like 21
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
Nucleotidyltransferase TGS-like 21
CheY-like Histidine-containing phosphotransfer domain, HPT domain 22
Thioredoxin-like GST C-terminal domain-like 21
GroES-like NAD(P)-binding Rossmann-fold domains 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 22
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 21
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
FKBP-like Triger factor/SurA peptide-binding domain-like 22
TGS-like ACT-like 21
Phospholipase D/nuclease Phospholipase D/nuclease 22
HD-domain/PDEase-like ACT-like 21
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
Nucleotidyltransferase ACT-like 21
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 22
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 22
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Lysozyme-like LysM domain 22
HD-domain/PDEase-like Nucleotidyltransferase 21
ACP-like alpha/beta-Hydrolases 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
HD-domain/PDEase-like TGS-like 21
ACP-like Acetyl-CoA synthetase-like 22
CoA-dependent acyltransferases CoA-dependent acyltransferases 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 22
Nucleic acid-binding proteins RuvA domain 2-like 22
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
NAD-binding domain of HMG-CoA reductase Substrate-binding domain of HMG-CoA reductase 21
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 22
Folate-binding domain Aminomethyltransferase beta-barrel domain 21
CBS-domain pair FAD-binding/transporter-associated domain-like 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 21
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
RuvA domain 2-like JAB1/MPN domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
LysM domain LysM domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
PheT/TilS domain Putative DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
L30e-like alpha/beta knot 11
LysM domain L,D-transpeptidase catalytic domain-like 11
ACP-like Thiolase-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Nucleotide-binding domain Riboflavin synthase domain-like 11
Acetyl-CoA synthetase-like Glycerol-3-phosphate (1)-acyltransferase 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
YajQ-like YajQ-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
PurS-like Class I glutamine amidotransferase-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
CoA-dependent acyltransferases Acetyl-CoA synthetase-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
DNA polymerase beta, N-terminal domain-like PHP domain-like 11
MetI-like MetI-like 11
Cupredoxins Cupredoxins 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
THUMP domain-like Adenine nucleotide alpha hydrolases-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
Barwin-like endoglucanases Sporulation related repeat 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
HCP-like HCP-like 11
Homeodomain-like Homeodomain-like 11
Homeodomain-like Probable bacterial effector-binding domain 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
GAF domain-like Nucleotide cyclase 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
N-terminal domain of DnaB helicase Hedgehog/intein (Hint) domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
ACT-like ACT-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
DPP6 N-terminal domain-like alpha/beta-Hydrolases 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Nucleotide cyclase EAL domain-like 11
DNA-glycosylase Nudix 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
GIY-YIG endonuclease RuvA domain 2-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Tropomyosin Smc hinge domain 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
PYP-like sensor domain (PAS domain) EAL domain-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Ribonuclease H-like DNA/RNA polymerases 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
YrdC/RibB RibA-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
PLP-binding barrel Acetyl-CoA synthetase-like 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
PDZ domain-like PDZ domain-like 11
PDZ domain-like ClpP/crotonase 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Nucleotidylyl transferase tRNA-binding arm 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
CoA-dependent acyltransferases alpha/beta-Hydrolases 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
"Winged helix" DNA-binding domain C-terminal domain of arginine repressor 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
PIN domain-like Ribonuclease H-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
Carbamate kinase-like ACT-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
lambda repressor-like DNA-binding domains RmlC-like cupins 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
CarD-like TRCF domain-like 11
TGS-like Class II aaRS and biotin synthetases 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
GHMP Kinase, C-terminal domain Nudix 11
HCP-like Sporulation related repeat 11
Translation proteins Translation proteins 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Translation proteins ThrRS/AlaRS common domain 11
Ribokinase-like Thiamin phosphate synthase 11
HMA, heavy metal-associated domain HAD-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Putative DNA-binding domain Translation proteins 11
DNA primase core DNA primase DnaG, C-terminal domain 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
ARM repeat P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
PurS-like PurM C-terminal domain-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
PurS-like PurM N-terminal domain-like 11
Thiolase-like NAD(P)-binding Rossmann-fold domains 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Nucleotide-binding domain Ferredoxin reductase-like, C-terminal NADP-linked domain 11
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins PheT/TilS domain 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Ribosome binding protein Y (YfiA homologue) Nucleic acid-binding proteins 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Nucleic acid-binding proteins GAD domain-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
RuvA domain 2-like BRCT domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
NAD(P)-binding Rossmann-fold domains Trimeric LpxA-like enzymes 11
Trigger factor ribosome-binding domain FKBP-like 11
PreATP-grasp domain PreATP-grasp domain 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
PYP-like sensor domain (PAS domain) Nucleotide cyclase 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
PHP domain-like Nucleic acid-binding proteins 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
MetI-like Periplasmic binding protein-like II 11
P-loop containing nucleoside triphosphate hydrolases Hedgehog/intein (Hint) domain 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 11
Calcium ATPase, transduction domain A HAD-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
TPR-like TPR-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
PUA domain-like Nucleotidylyl transferase 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
FAD-linked oxidoreductase ALDH-like 11
PIN domain-like DNA/RNA polymerases 11
PurS-like FGAM synthase PurL, linker domain 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
HAD-like Calcium ATPase, transmembrane domain M 11
ClpP/crotonase NfeD domain-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Ribosomal protein L6 Ribosomal protein L6 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
GroEL-intermediate domain like GroEL apical domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
Class II aaRS and biotin synthetases Translation proteins 11
MesJ substrate recognition domain-like PheT/TilS domain 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Acetyl-CoA synthetase-like alpha/beta-Hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Tropomyosin 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Mss4-like Peptide methionine sulfoxide reductase 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Nucleotidylyl transferase P-loop containing nucleoside triphosphate hydrolases 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
ClpP/crotonase ClpP/crotonase 11
DNA clamp DNA clamp 11
ACP-like ACP-like 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
ACP-like FabD/lysophospholipase-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
PreATP-grasp domain Single hybrid motif 11
TGS-like ThrRS/AlaRS common domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
Outer membrane efflux proteins (OEP) Sporulation related repeat 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Rudiment single hybrid motif Single hybrid motif 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Ribulose-phoshate binding barrel Tryptophan synthase beta subunit-like PLP-dependent enzymes 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 11
Zinc beta-ribbon DNA primase core 11
UROD/MetE-like UROD/MetE-like 11
Heme-dependent catalase-like Class I glutamine amidotransferase-like 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Formyltransferase FMT C-terminal domain-like 11
Protein kinase-like (PK-like) Acyl-CoA N-acyltransferases (Nat) 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
Ribosomal protein S5 domain 2-like Nudix 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
ACP-like NAD(P)-binding Rossmann-fold domains 11
Thiolase-like FabD/lysophospholipase-like 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Trimeric LpxA-like enzymes 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
HlyD-like secretion proteins Outer membrane efflux proteins (OEP) 11
RNase III domain-like dsRNA-binding domain-like 11
Pseudouridine synthase PUA domain-like 11
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
"Winged helix" DNA-binding domain Restriction endonuclease-like 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
TGS-like Class II aaRS ABD-related 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Translation proteins PRC-barrel domain 11
Zinc beta-ribbon Zinc beta-ribbon 11
ACP-like Glycerol-3-phosphate (1)-acyltransferase 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
CoA-dependent acyltransferases ACP-like 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
GAF domain-like Phosphohistidine domain 11
Nucleic acid-binding proteins BRCT domain 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 11
YjeF N-terminal domain-like Ribokinase-like 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
Trypsin-like serine proteases PDZ domain-like 11
Pentapeptide repeat-like Pentapeptide repeat-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
F-box domain Ankyrin repeat 11
Nucleotidyltransferase PHP domain-like 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 11
lambda repressor-like DNA-binding domains LexA/Signal peptidase 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
GroEL equatorial domain-like GroEL apical domain-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11

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