SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Burkholderia glumae BGR1

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


Add or remove domain pairs

The links below permit the addition or removal of specific sets of domain combination pairs.


Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Add or remove genomes

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Add or remove genomes:
Include genomes:
Exclude genomes:


Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

799 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 901
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 4326
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 3614
GroES-like NAD(P)-binding Rossmann-fold domains 285
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 266
Homeodomain-like Homeodomain-like 259
CheY-like C-terminal effector domain of the bipartite response regulators 242
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 203
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 203
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 208
Homeodomain-like Ribonuclease H-like 182
Actin-like ATPase domain Actin-like ATPase domain 176
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 173
Acetyl-CoA synthetase-like ACP-like 1615
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 164
CoA-dependent acyltransferases ACP-like 1615
CheY-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1613
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 161
Phage tail proteins Phage tail proteins 166
CoA-dependent acyltransferases Acetyl-CoA synthetase-like 1514
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1513
CoA-dependent acyltransferases CoA-dependent acyltransferases 1514
CheY-like Homodimeric domain of signal transducing histidine kinase 1512
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 151
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 156
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 142
Phage tail proteins gp5 N-terminal domain-like 144
Thioredoxin-like GST C-terminal domain-like 131
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 1312
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 125
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 124
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 113
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 115
Cytochrome c Cytochrome c 117
"Winged helix" DNA-binding domain GAF domain-like 111
"Winged helix" DNA-binding domain PLP-dependent transferases 101
ParB/Sulfiredoxin KorB DNA-binding domain-like 102
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 106
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 109
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 104
Thiolase-like Thiolase-like 101
Thiolase-like ACP-like 1010
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 104
CheY-like Homeodomain-like 104
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 104
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 104
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 104
P-loop containing nucleoside triphosphate hydrolases MOP-like 91
Class I glutamine amidotransferase-like Homeodomain-like 91
P-loop containing nucleoside triphosphate hydrolases CheY-like 93
P-loop containing nucleoside triphosphate hydrolases Translation proteins 95
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 98
ISP domain Bet v1-like 92
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 94
ACP-like ACP-like 99
Acetyl-CoA synthetase-like Acetyl-CoA synthetase-like 88
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 82
(Trans)glycosidases Glycosyl hydrolase domain 87
FabD/lysophospholipase-like ACP-like 88
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 82
ACP-like NAD(P)-binding Rossmann-fold domains 88
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 82
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 88
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 81
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 81
Thiolase-like FabD/lysophospholipase-like 88
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 82
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 84
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 88
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 77
Thiolase-like NAD(P)-binding Rossmann-fold domains 77
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 75
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 71
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 73
Enolase N-terminal domain-like Enolase C-terminal domain-like 71
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 73
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 77
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 66
Triger factor/SurA peptide-binding domain-like FKBP-like 65
PreATP-grasp domain Rudiment single hybrid motif 62
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 66
GAF domain-like Homodimeric domain of signal transducing histidine kinase 66
lambda repressor-like DNA-binding domains RmlC-like cupins 61
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 63
Homeodomain-like SIS domain 62
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 66
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 62
HlyD-like secretion proteins HlyD-like secretion proteins 53
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 51
Adhesin YadA, collagen-binding domain Pili subunits 55
PYP-like sensor domain (PAS domain) CheY-like 55
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 53
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 54
Phospholipase D/nuclease Phospholipase D/nuclease 55
Nucleotide cyclase EAL domain-like 53
TPR-like TPR-like 55
Lysozyme-like beta-lactamase/transpeptidase-like 53
Alpha-L RNA-binding motif Pseudouridine synthase 53
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 52
gp5 N-terminal domain-like Phage fibre proteins 53
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 51
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 55
Phage tail proteins Phage fibre proteins 53
Calcium ATPase, transduction domain A HAD-like 44
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 42
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 42
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 44
Calcium ATPase, transmembrane domain M HAD-like 44
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 42
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 42
Adhesin YadA, collagen-binding domain Adhesin YadA, collagen-binding domain 44
Translation proteins EF-G C-terminal domain-like 42
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 41
CheY-like CheY-like 44
EF-G C-terminal domain-like EF-G C-terminal domain-like 42
cAMP-binding domain-like "Winged helix" DNA-binding domain 41
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 43
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
PurM N-terminal domain-like PurM C-terminal domain-like 42
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 42
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
RmlC-like cupins Homeodomain-like 42
Aspartate receptor, ligand-binding domain Methyl-accepting chemotaxis protein (MCP) signaling domain 42
Histidine-containing phosphotransfer domain, HPT domain CheY-like 44
Regulatory protein AraC Homeodomain-like 43
Aconitase iron-sulfur domain LeuD/IlvD-like 42
GAF domain-like PYP-like sensor domain (PAS domain) 44
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 42
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 42
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 44
"Winged helix" DNA-binding domain Chorismate lyase-like 41
E set domains (Trans)glycosidases 44
GAF domain-like CheY-like 44
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 33
HD-domain/PDEase-like Nucleotidyltransferase 32
PDZ domain-like PDZ domain-like 32
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 32
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 33
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
RuvA domain 2-like Nucleic acid-binding proteins 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Histidine-containing phosphotransfer domain, HPT domain CheW-like 33
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 31
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 32
E set domains Glycosyl hydrolase domain 33
Protease propeptides/inhibitors Subtilisin-like 32
Trypsin-like serine proteases PDZ domain-like 32
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Nucleotidyltransferase ACT-like 32
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 32
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 33
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 33
ACT-like Formyltransferase 32
Origin of replication-binding domain, RBD-like P-loop containing nucleoside triphosphate hydrolases 32
PLP-binding barrel Alanine racemase C-terminal domain-like 32
GAF domain-like Nucleotide cyclase 32
HD-domain/PDEase-like ACT-like 32
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 31
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 32
NAD(P)-binding Rossmann-fold domains ClpP/crotonase 32
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 32
Ribosomal protein S5 domain 2-like EF-G C-terminal domain-like 32
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 33
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 33
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 33
EAL domain-like Sensory domain-like 31
PYP-like sensor domain (PAS domain) Nucleotide cyclase 32
GroES-like ACP-like 33
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 33
C-terminal effector domain of the bipartite response regulators P-loop containing nucleoside triphosphate hydrolases 32
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
ACP-like alpha/beta-Hydrolases 33
Aldolase post-HMGL domain-like 33
CBS-domain pair FAD-binding/transporter-associated domain-like 31
FabD/lysophospholipase-like GroES-like 33
Galactose-binding domain-like Galactose-binding domain-like 32
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 33
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 32
Folate-binding domain Aminomethyltransferase beta-barrel domain 33
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 31
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 31
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 31
6-phosphogluconate dehydrogenase C-terminal domain-like ClpP/crotonase 32
Single hybrid motif CoA-dependent acyltransferases 33
DsbC/DsbG N-terminal domain-like Thioredoxin-like 32
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 33
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 33
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
Thiolase-like GroES-like 33
CheY-like Methylesterase CheB, C-terminal domain 31
Probable ACP-binding domain of malonyl-CoA ACP transacylase GroES-like 33
ACT-like ACT-like 33
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 33
Cytidine deaminase-like Dihydrofolate reductase-like 21
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 22
lambda repressor-like DNA-binding domains CheY-like 21
MetI-like MetI-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 21
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 21
Succinyl-CoA synthetase domains Glutathione synthetase ATP-binding domain-like 22
GAF domain-like GAF domain-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 22
Nucleotide-diphospho-sugar transferases RmlC-like cupins 21
PYP-like sensor domain (PAS domain) Homeodomain-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Clc chloride channel CBS-domain pair 21
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 21
Homodimeric domain of signal transducing histidine kinase Homodimeric domain of signal transducing histidine kinase 22
PapD-like Periplasmic chaperone C-domain 22
Homodimeric domain of signal transducing histidine kinase CheW-like 22
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 22
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 22
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
Periplasmic binding protein-like II ACT-like 21
2Fe-2S ferredoxin-like alpha-helical ferredoxin 21
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 22
L30e-like alpha/beta knot 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
CoA-dependent acyltransferases alpha/beta-Hydrolases 22
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 22
Translation proteins Ribosomal protein S5 domain 2-like 21
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 22
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 22
(Trans)glycosidases Class I glutamine amidotransferase-like 21
Translation proteins ThrRS/AlaRS common domain 22
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Acetyl-CoA synthetase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 22
MoeA N-terminal region -like MoeA C-terminal domain-like 21
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 22
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 21
Ribonuclease H-like DNA/RNA polymerases 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
Acetyl-CoA synthetase-like FabD/lysophospholipase-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 22
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 22
CoA-dependent acyltransferases Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 22
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 22
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
CoA-dependent acyltransferases Thiolase-like 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 21
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 21
CoA-dependent acyltransferases NAD(P)-binding Rossmann-fold domains 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 21
HD-domain/PDEase-like TGS-like 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 22
Class I glutamine amidotransferase-like Glycosyl hydrolase domain 21
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 22
UROD/MetE-like UROD/MetE-like 21
P-loop containing nucleoside triphosphate hydrolases CBS-domain pair 21
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
EAL domain-like HD-domain/PDEase-like 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Aspartate/glutamate racemase Aspartate/glutamate racemase 22
GroEL-intermediate domain like GroEL apical domain-like 21
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
Nqo1 middle domain-like Nqo1C-terminal domain-like 22
Pentapeptide repeat-like Pentapeptide repeat-like 22
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 21
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 22
Acetyl-CoA synthetase-like alpha/beta-Hydrolases 22
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
His-Me finger endonucleases DNA-binding domain 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 22
FAD/NAD(P)-binding domain Folate-binding domain 22
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 22
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 21
CheW-like CheY-like 22
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 22
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 22
PYP-like sensor domain (PAS domain) EAL domain-like 21
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 21
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 21
CoA-dependent acyltransferases FabD/lysophospholipase-like 22
HMA, heavy metal-associated domain HAD-like 22
TGS-like ACT-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 21
GroEL equatorial domain-like GroEL-intermediate domain like 21
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 22
(Trans)glycosidases Galactose-binding domain-like 22
Acetyl-CoA synthetase-like Thiolase-like 22
GroEL equatorial domain-like GroEL apical domain-like 21
UDP-Glycosyltransferase/glycogen phosphorylase Nucleotide-diphospho-sugar transferases 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
Formyltransferase FMT C-terminal domain-like 21
LysM domain Lysozyme-like 22
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
Chorismate mutase II ACT-like 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 21
DPP6 N-terminal domain-like alpha/beta-Hydrolases 21
MFS general substrate transporter MFS general substrate transporter 21
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 22
PH0987 N-terminal domain-like Cyclophilin-like 21
Acetyl-CoA synthetase-like NAD(P)-binding Rossmann-fold domains 22
Chorismate mutase II Periplasmic binding protein-like II 21
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 22
Nucleotidyltransferase TGS-like 21
S-adenosyl-L-methionine-dependent methyltransferases UDP-Glycosyltransferase/glycogen phosphorylase 11
Duplicated hybrid motif Phosphoenolpyruvate/pyruvate domain 11
PurS-like Class I glutamine amidotransferase-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
DNA-glycosylase Nudix 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Translation proteins "Winged helix" DNA-binding domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Galactose mutarotase-like (Trans)glycosidases 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
S-adenosyl-L-methionine-dependent methyltransferases TPR-like 11
S-adenosyl-L-methionine-dependent methyltransferases ACP-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Single hybrid motif FAD/NAD(P)-binding domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Tex N-terminal region-like Ribonuclease H-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
ABC transporter transmembrane region CheY-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
GAF domain-like C-terminal effector domain of the bipartite response regulators 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
PLP-dependent transferases PLP-dependent transferases 11
alpha-helical ferredoxin Nucleotide-binding domain 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Histidine-containing phosphotransfer domain, HPT domain CheY-binding domain of CheA 11
ADC synthase Class I glutamine amidotransferase-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase PP2C-like 11
CheY-binding domain of CheA ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Adenine nucleotide alpha hydrolases-like GAF domain-like 11
Cytochrome c oxidase subunit II-like, transmembrane region OmpA-like 11
RuvA domain 2-like BRCT domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
GroES-like alpha/beta-Hydrolases 11
PheT/TilS domain Putative DNA-binding domain 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Glycosyl hydrolase domain Galactose-binding domain-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
EAL domain-like CBS-domain pair 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
ATP-dependent DNA ligase DNA-binding domain Nucleic acid-binding proteins 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
(Trans)glycosidases Ricin B-like lectins 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
gp5 N-terminal domain-like alpha/beta-Hydrolases 11
WD40 repeat-like WD40 repeat-like 11
Pseudouridine synthase PUA domain-like 11
Rudiment single hybrid motif Single hybrid motif 11
E set domains E set domains 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
PIN domain-like Ribonuclease H-like 11
LysM domain Duplicated hybrid motif 11
Resolvase-like Homeodomain-like 11
Nucleotide-binding domain Nucleotide-binding domain 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
PreATP-grasp domain PreATP-grasp domain 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
FabD/lysophospholipase-like alpha/beta-Hydrolases 11
Macro domain-like Zn-dependent exopeptidases 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Glycosyl hydrolase domain Protein kinase-like (PK-like) 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
GAF domain-like HD-domain/PDEase-like 11
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Transmembrane di-heme cytochromes Calcium ATPase, transduction domain A 11
TATA-box binding protein-like DNA-glycosylase 11
GAF domain-like Homeodomain-like 11
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Methionine synthase domain Methionine synthase activation domain-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 11
Cupredoxins Cupredoxins 11
MalF N-terminal region-like MetI-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase alpha/beta-Hydrolases 11
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
YgfB-like Sec-C motif 11
Acid phosphatase/Vanadium-dependent haloperoxidase Pectin lyase-like 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
GroES-like GroES-like 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
ADC-like Riboflavin synthase domain-like 11
Duplicated hybrid motif HPr-like 11
Heme-dependent catalase-like Class I glutamine amidotransferase-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Nucleic acid-binding proteins BRCT domain 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
PrpR receptor domain-like PYP-like sensor domain (PAS domain) 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Tricorn protease N-terminal domain DPP6 N-terminal domain-like 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Nucleic acid-binding proteins GAD domain-like 11
CBS-domain pair PP2C-like 11
Ribosomal protein L6 Ribosomal protein L6 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Riboflavin synthase domain-like 11
FKBP-like FKBP-like 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
YajQ-like YajQ-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Creatinase/prolidase N-terminal domain Creatinase/prolidase N-terminal domain 11
FMN-dependent nitroreductase-like FMN-dependent nitroreductase-like 11
Nucleotidylyl transferase tRNA-binding arm 11
DNA clamp DNA clamp 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
ClpP/crotonase ClpP/crotonase 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
Class II aaRS and biotin synthetases GAD domain-like 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases GroES-like 11
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 11
CheY-binding domain of CheA Homodimeric domain of signal transducing histidine kinase 11
PurS-like FGAM synthase PurL, linker domain 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
CheC-like Surface presentation of antigens (SPOA) 11
MOP-like MOP-like 11
RNase III domain-like dsRNA-binding domain-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Nucleic acid-binding proteins PheT/TilS domain 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
RuvA domain 2-like RuvA domain 2-like 11
Restriction endonuclease-like S-adenosyl-L-methionine-dependent methyltransferases 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
YrdC/RibB RibA-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Duplicated hybrid motif Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
P-loop containing nucleoside triphosphate hydrolases Zinc beta-ribbon 11
FAD-linked oxidoreductase ALDH-like 11
P-loop containing nucleoside triphosphate hydrolases TPR-like 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
FliG FliG 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
PRC-barrel domain PRC-barrel domain 11
Actin-like ATPase domain Homeodomain-like 11
C-terminal effector domain of the bipartite response regulators TPR-like 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Dihydropteroate synthetase-like Methionine synthase domain 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
MesJ substrate recognition domain-like PheT/TilS domain 11
HD-domain/PDEase-like HD-domain/PDEase-like 11
Duplicated hybrid motif Phosphohistidine domain 11
lambda repressor-like DNA-binding domains LexA/Signal peptidase 11
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
TGS-like ThrRS/AlaRS common domain 11
PurS-like PurM C-terminal domain-like 11
Translation proteins PRC-barrel domain 11
Pili subunits GspK insert domain-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 11
MetI-like P-loop containing nucleoside triphosphate hydrolases 11
Thioredoxin-like Acyl-CoA N-acyltransferases (Nat) 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Putative DNA-binding domain GAF domain-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Carbamate kinase-like PUA domain-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
HMA, heavy metal-associated domain Metal cation-transporting ATPase, ATP-binding domain N 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
GIY-YIG endonuclease RuvA domain 2-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
DNA topoisomerase I domain DNA breaking-rejoining enzymes 11
YgbK-like Isocitrate/Isopropylmalate dehydrogenase-like 11
CoA-transferase family III (CaiB/BaiF) CoA-transferase family III (CaiB/BaiF) 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
S-adenosyl-L-methionine-dependent methyltransferases Nucleotide-diphospho-sugar transferases 11
PIN domain-like DNA/RNA polymerases 11
FAD/NAD(P)-binding domain alpha/beta-Hydrolases 11
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 11
Single hybrid motif Single hybrid motif 11
PrpR receptor domain-like Homeodomain-like 11
alpha/beta-Hydrolases NTF2-like 11
DinB/YfiT-like putative metalloenzymes C-type lectin-like 11
P-loop containing nucleoside triphosphate hydrolases S-adenosyl-L-methionine-dependent methyltransferases 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
CheW-like CheW-like 11
ADC-like Flavoproteins 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Concanavalin A-like lectins/glucanases AbfB domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
C-terminal effector domain of the bipartite response regulators C-terminal effector domain of the bipartite response regulators 11
FMN-linked oxidoreductases Nucleotide-binding domain 11
Nucleotide-diphospho-sugar transferases PilZ domain-like 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
Cytochrome c oxidase subunit I-like Cytochrome c oxidase subunit III-like 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Ribonuclease H-like RuvA domain 2-like 11
ABC transporter involved in vitamin B12 uptake, BtuC P-loop containing nucleoside triphosphate hydrolases 11
Phase 1 flagellin Phase 1 flagellin 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Bacterial muramidases Lysozyme-like 11
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
Formate dehydrogenase/DMSO reductase, domains 1-3 Flavoproteins 11
ABC transporter involved in vitamin B12 uptake, BtuC ABC transporter involved in vitamin B12 uptake, BtuC 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
CBS-domain pair Nucleotide cyclase 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Cupredoxins OmpA-like 11
Ribonuclease H-like Nucleic acid-binding proteins 11
YjeF N-terminal domain-like Ribokinase-like 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Ribbon-helix-helix N-terminal domain of bifunctional PutA protein 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
HprK N-terminal domain-like PEP carboxykinase-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
CarD-like TRCF domain-like 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Periplasmic binding protein-like I Homeodomain-like 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Flavoproteins Riboflavin synthase domain-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
Cytochrome c OmpA-like 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
PrpR receptor domain-like P-loop containing nucleoside triphosphate hydrolases 11
Thioredoxin-like TPR-like 11
PDZ domain-like ClpP/crotonase 11
Methyl-accepting chemotaxis protein (MCP) signaling domain Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
PPK N-terminal domain-like PHP14-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
Translation proteins Translation proteins 11
HPr-like Phosphoenolpyruvate/pyruvate domain 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Tex N-terminal region-like RuvA domain 2-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
PRC-barrel domain Formin homology 2 domain (FH2 domain) 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
LysM domain LysM domain 11
Putative DNA-binding domain Translation proteins 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
alpha/beta-Hydrolases alpha/beta-Hydrolases 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase S-adenosyl-L-methionine-dependent methyltransferases 11
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Globin-like Riboflavin synthase domain-like 11
CheY-like Nucleotide cyclase 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Phage fibre proteins alpha/beta-Hydrolases 11
Zinc beta-ribbon DNA primase core 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Transmembrane di-heme cytochromes Calcium ATPase, transmembrane domain M 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
ADC-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Class II aaRS and biotin synthetases Translation proteins 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
Ribonuclease H-like mu transposase, C-terminal domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
PUA domain-like alpha/beta knot 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
NagB/RpiA/CoA transferase-like 4Fe-4S ferredoxins 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
2Fe-2S ferredoxin-like ADC-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
Cupredoxins Cytochrome c 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
Metallo-hydrolase/oxidoreductase Acyl-CoA N-acyltransferases (Nat) 11
Chaperone J-domain HSP40/DnaJ peptide-binding domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
FabD/lysophospholipase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Transmembrane di-heme cytochromes HAD-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Ribonuclease H-like GIY-YIG endonuclease 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
RmlC-like cupins RmlC-like cupins 11
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Thioredoxin-like Thioredoxin-like 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
Purple acid phosphatase, N-terminal domain Metallo-dependent phosphatases 11
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
HemD-like HemD-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Galactose-binding domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
L domain-like Protein kinase-like (PK-like) 11
Duplicated hybrid motif Lysozyme-like 11
PYP-like sensor domain (PAS domain) PP2C-like 11
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Transmembrane di-heme cytochromes Metal cation-transporting ATPase, ATP-binding domain N 11
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 11
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 11
Trigger factor ribosome-binding domain FKBP-like 11
FAD-linked reductases, C-terminal domain Aminomethyltransferase beta-barrel domain 11
Thiolase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain "Winged helix" DNA-binding domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Ribbon-helix-helix FAD-linked oxidoreductase 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Hsp33 domain HSP33 redox switch-like 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
CheY-binding domain of CheA CheW-like 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
TGS-like Class II aaRS ABD-related 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Phosphoenolpyruvate/pyruvate domain Nucleotide-diphospho-sugar transferases 11
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Phage tail proteins alpha/beta-Hydrolases 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
MOSC N-terminal domain-like PK beta-barrel domain-like 11
PurS-like PurM N-terminal domain-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Calcium-dependent phosphotriesterase Nitrous oxide reductase, N-terminal domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
NHL repeat 3-carboxy-cis,cis-mucoante lactonizing enzyme 11
TGS-like Class II aaRS and biotin synthetases 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
(Trans)glycosidases (Trans)glycosidases 11
Galactose-binding domain-like Ricin B-like lectins 11
Metalloproteases ("zincins"), catalytic domain PDZ domain-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Ribbon-helix-helix ALDH-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
TTHA1013/TTHA0281-like Ribbon-helix-helix 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PreATP-grasp domain Single hybrid motif 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Galactose mutarotase-like Glycosyl hydrolase domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
CbiG N-terminal domain-like Tetrapyrrole methylase 11
FAD-linked reductases, C-terminal domain Folate-binding domain 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Actin-like ATPase domain SIS domain 11
NAD(P)-binding Rossmann-fold domains alpha/beta-Hydrolases 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Thiolase-like alpha/beta-Hydrolases 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
4Fe-4S ferredoxins ADC-like 11
Glucose permease domain IIB Glucose permease domain IIB 11
DAK1/DegV-like DhaL-like 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
ATP-dependent DNA ligase DNA-binding domain DNA ligase/mRNA capping enzyme, catalytic domain 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Carbamate kinase-like ACT-like 11
P-loop containing nucleoside triphosphate hydrolases Bacterial luciferase-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
PHP14-like Phospholipase D/nuclease 11
HPr-like Phosphohistidine domain 11

Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes · Domain combination pairs ]