SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Sulfurovum sp. NBC37-1

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

525 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 2810
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 1610
CheY-like C-terminal effector domain of the bipartite response regulators 131
Nucleotide cyclase EAL domain-like 127
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 117
Actin-like ATPase domain Actin-like ATPase domain 105
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 97
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 93
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 95
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 95
Cytochrome c Cytochrome c 84
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 83
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 84
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 84
PYP-like sensor domain (PAS domain) Nucleotide cyclase 86
PYP-like sensor domain (PAS domain) EAL domain-like 75
Homodimeric domain of signal transducing histidine kinase CheY-like 75
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 54
P-loop containing nucleoside triphosphate hydrolases Translation proteins 55
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 52
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 54
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 55
HAD-like Calcium ATPase, transmembrane domain M 55
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 53
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 53
Calcium ATPase, transduction domain A HAD-like 55
Phospholipase D/nuclease Phospholipase D/nuclease 54
PGBD-like L,D-transpeptidase catalytic domain-like 52
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 51
PurM N-terminal domain-like PurM C-terminal domain-like 52
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 53
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 52
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 41
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 43
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 43
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 41
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 41
Ribosomal protein S5 domain 2-like P-loop containing nucleoside triphosphate hydrolases 44
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 41
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 44
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 41
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 43
TT1751-like TT1751-like 42
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 41
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 44
PLP-binding barrel Alanine racemase C-terminal domain-like 42
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 41
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 41
Enolase N-terminal domain-like Enolase C-terminal domain-like 31
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 33
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 32
L30e-like alpha/beta knot 31
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 32
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 31
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
GAF domain-like CheY-like 32
FAD/NAD(P)-binding domain HI0933 insert domain-like 31
Cytochrome c Thioredoxin-like 31
Oxidoreductase molybdopterin-binding domain E set domains 31
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 32
Nucleic acid-binding proteins RuvA domain 2-like 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 33
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 33
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 32
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Cupredoxins Cupredoxins 32
2Fe-2S ferredoxin-like alpha-helical ferredoxin 32
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 33
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
Nqo5-like HydB/Nqo4-like 21
CBS-domain pair MgtE membrane domain-like 21
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
Rubredoxin-like Ferritin-like 21
NAD(P)-binding Rossmann-fold domains ACT-like 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 22
GAF domain-like Homodimeric domain of signal transducing histidine kinase 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
PYP-like sensor domain (PAS domain) CheY-like 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
ACT-like ACT-like 22
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 21
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 21
Invasin/intimin cell-adhesion fragments Invasin/intimin cell-adhesion fragments 22
MgtE N-terminal domain-like CBS-domain pair 21
NAD(P)-binding Rossmann-fold domains FAD/NAD(P)-binding domain 22
Homeodomain-like Homeodomain-like 22
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
FKBP-like Triger factor/SurA peptide-binding domain-like 22
cAMP-binding domain-like "Winged helix" DNA-binding domain 21
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
TPR-like TPR-like 22
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 21
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
Rubredoxin-like Rubredoxin-like 21
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 21
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 21
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 22
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 21
TPR-like P-loop containing nucleoside triphosphate hydrolases 22
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 21
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
MgtE N-terminal domain-like MgtE membrane domain-like 21
Thioredoxin-like Six-hairpin glycosidases 21
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 21
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 21
Voltage-gated potassium channels TrkA C-terminal domain-like 22
HD-domain/PDEase-like Nucleotidyltransferase 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 22
Single hybrid motif CoA-dependent acyltransferases 21
MoeA N-terminal region -like MoeA C-terminal domain-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 22
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 21
PreATP-grasp domain Rudiment single hybrid motif 21
Alpha-L RNA-binding motif Pseudouridine synthase 21
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 21
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 21
Formyltransferase FMT C-terminal domain-like 22
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 21
Translation proteins EF-G C-terminal domain-like 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 21
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
beta-lactamase/transpeptidase-like Sporulation related repeat 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Multiheme cytochromes TPR-like 11
Aldolase post-HMGL domain-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
post-HMGL domain-like Single hybrid motif 11
Ferritin-like Calcium ATPase, transmembrane domain M 11
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 11
GroEL equatorial domain-like GroEL apical domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Guanido kinase N-terminal domain Glutamine synthetase/guanido kinase 11
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 11
Nucleotidylyl transferase GatB/YqeY motif 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Nitrous oxide reductase, N-terminal domain Cupredoxins 11
Chorismate mutase II Periplasmic binding protein-like II 11
Zn-dependent exopeptidases Fibronectin type III 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins GAD domain-like 11
Sec63 N-terminal domain-like Nucleotidyltransferase 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
GIY-YIG endonuclease RuvA domain 2-like 11
TPR-like HCP-like 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Rad50 coiled-coil Zn hook 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Aldolase Single hybrid motif 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Cupredoxins Cytochrome c 11
Glutathione synthetase ATP-binding domain-like RuvA domain 2-like 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Metallo-hydrolase/oxidoreductase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Serine metabolism enzymes domain ACT-like 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
Carbamate kinase-like ACT-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
GAF domain-like Nucleotide cyclase 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Nucleotidylyl transferase tRNA-binding arm 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Toll/Interleukin receptor TIR domain WD40 repeat-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
MetI-like MetI-like 11
Cysteine proteinases Sporulation related repeat 11
MOP-like MOP-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
RuvA domain 2-like BRCT domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
CarD-like TRCF domain-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
UROD/MetE-like UROD/MetE-like 11
Quinoprotein alcohol dehydrogenase-like Quinoprotein alcohol dehydrogenase-like 11
FAD/NAD(P)-binding domain HydA/Nqo6-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Periplasmic binding protein-like II Periplasmic binding protein-like II 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Nucleotide-diphospho-sugar transferases Phosphoglucomutase, first 3 domains 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
YajQ-like YajQ-like 11
PIN domain-like DNA/RNA polymerases 11
Periplasmic binding protein-like II ACT-like 11
Homocysteine S-methyltransferase Methionine synthase domain 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
CheY-like CheY-like 11
NAD(P)-binding Rossmann-fold domains Citrate synthase 11
Hedgehog/intein (Hint) domain P-loop containing nucleoside triphosphate hydrolases 11
Translation proteins Translation proteins 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
HD-domain/PDEase-like ACT-like 11
Ferritin-like HAD-like 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Hemerythrin-like EAL domain-like 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 11
Hemerythrin-like PYP-like sensor domain (PAS domain) 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Nqo1C-terminal domain-like Nucleotide-binding domain 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Zinc beta-ribbon Zinc beta-ribbon 11
Nucleotide-binding domain Nucleotide-binding domain 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Dihydropteroate synthetase-like Methionine synthase domain 11
NAD(P)-binding Rossmann-fold domains FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Toll/Interleukin receptor TIR domain P-loop containing nucleoside triphosphate hydrolases 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
GAF domain-like PYP-like sensor domain (PAS domain) 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
DNA-glycosylase Nudix 11
alpha-helical ferredoxin alpha-helical ferredoxin 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
"Winged helix" DNA-binding domain HRDC-like 11
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 11
N-terminal domain of DnaB helicase Homing endonucleases 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
Chorismate mutase II ACT-like 11
Nucleic acid-binding proteins BRCT domain 11
RNase III domain-like dsRNA-binding domain-like 11
YrdC/RibB RibA-like 11
WD40 repeat-like DPP6 N-terminal domain-like 11
PDZ domain-like ClpP/crotonase 11
Multiheme cytochromes Multiheme cytochromes 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
HPr-like Phosphohistidine domain 11
Translation proteins PRC-barrel domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Hedgehog/intein (Hint) domain Homing endonucleases 11
Tex N-terminal region-like RuvA domain 2-like 11
beta-N-acetylhexosaminidase-like domain (Trans)glycosidases 11
Trimeric LpxA-like enzymes Phosphoglucomutase, C-terminal domain 11
DNA clamp DNA clamp 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
MFS general substrate transporter Acetyl-CoA synthetase-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
HAD-like UDP-Glycosyltransferase/glycogen phosphorylase 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Cytochrome c C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase 11
LysM domain Cysteine proteinases 11
LysM domain LysM domain 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Rhodanese/Cell cycle control phosphatase P-loop containing nucleoside triphosphate hydrolases 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
PUA domain-like Nucleotidylyl transferase 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
Glycoside hydrolase/deacetylase Galactose mutarotase-like 11
Macro domain-like Zn-dependent exopeptidases 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
RmlC-like cupins Homeodomain-like 11
Trimeric LpxA-like enzymes Phosphoglucomutase, first 3 domains 11
Lysozyme-like LysM domain 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Nucleic acid-binding proteins PheT/TilS domain 11
Sec63 N-terminal domain-like PHP domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
HMA, heavy metal-associated domain HAD-like 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
HPr-like Phosphoenolpyruvate/pyruvate domain 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
FMT C-terminal domain-like ClpP/crotonase 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Nqo1C-terminal domain-like alpha-helical ferredoxin 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
ACT-like Formyltransferase 11
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
PHP14-like Phospholipase D/nuclease 11
DNA polymerase beta, N-terminal domain-like Sec63 N-terminal domain-like 11
DNA polymerase beta, N-terminal domain-like PHP domain-like 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
(Trans)glycosidases Glycosyl hydrolase domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Homing endonucleases P-loop containing nucleoside triphosphate hydrolases 11
Tex N-terminal region-like Ribonuclease H-like 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
THUMP domain-like Adenine nucleotide alpha hydrolases-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Trigger factor ribosome-binding domain FKBP-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Ferritin-like Calcium ATPase, transduction domain A 11
Translation proteins ThrRS/AlaRS common domain 11
HisI-like all-alpha NTP pyrophosphatases 11
BLRF2-like Porins 11
Metallo-hydrolase/oxidoreductase GAF domain-like 11
N-terminal domain of DnaB helicase Hedgehog/intein (Hint) domain 11
Nucleotide-diphospho-sugar transferases Phosphoglucomutase, C-terminal domain 11
Metallo-hydrolase/oxidoreductase Homodimeric domain of signal transducing histidine kinase 11
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
SufE/NifU Fe-S cluster assembly (FSCA) domain-like 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
YjeF N-terminal domain-like Ribokinase-like 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
"Winged helix" DNA-binding domain MOP-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
THUMP domain-like Rhodanese/Cell cycle control phosphatase 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Multidrug efflux transporter AcrB transmembrane domain Nucleotide cyclase 11
cAMP-binding domain-like CBS-domain pair 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
RuvA domain 2-like RuvA domain 2-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Thiolase-like Thiolase-like 11
beta and beta-prime subunits of DNA dependent RNA-polymerase beta and beta-prime subunits of DNA dependent RNA-polymerase 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
Mss4-like Peptide methionine sulfoxide reductase 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 11
Toll/Interleukin receptor TIR domain Toll/Interleukin receptor TIR domain 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
CheY-like Nucleotide cyclase 11
PUA domain-like alpha/beta knot 11
Zinc beta-ribbon DNA primase core 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Ribonuclease H-like DNA/RNA polymerases 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Nucleotidyltransferase TGS-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Nucleotidyltransferase ACT-like 11
Sensory domain-like PP2C-like 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Transposase IS200-like KorB DNA-binding domain-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
Toll/Interleukin receptor TIR domain DPP6 N-terminal domain-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
LeuD/IlvD-like Aconitase iron-sulfur domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
vWA-like TPR-like 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
PreATP-grasp domain PreATP-grasp domain 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
alpha-helical ferredoxin Nucleotide-binding domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Hemerythrin-like Nucleotide cyclase 11
PIN domain-like Ribonuclease H-like 11
Trypsin-like serine proteases PDZ domain-like 11
Periplasmic binding protein-like II Nucleotide cyclase 11
Cytochrome c Multiheme cytochromes 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Ferredoxin thioredoxin reductase (FTR), catalytic beta chain Rhodanese/Cell cycle control phosphatase 11
"Winged helix" DNA-binding domain PLP-dependent transferases 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Galactose-binding domain-like TSP type-3 repeat 11
PPK N-terminal domain-like PHP14-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
GroEL-intermediate domain like GroEL apical domain-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
PP2C-like Protein kinase-like (PK-like) 11
C-type lectin-like S-adenosyl-L-methionine-dependent methyltransferases 11
HIT-like HIT-like 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
PheT/TilS domain Putative DNA-binding domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
HD-domain/PDEase-like TGS-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
SP0561-like SirA-like 11
DPP6 N-terminal domain-like DPP6 N-terminal domain-like 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Translation proteins Ribosomal protein S5 domain 2-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Acyl-CoA N-acyltransferases (Nat) 11
Ribosomal protein L6 Ribosomal protein L6 11
NTF2-like Sec-C motif 11
Formyltransferase ClpP/crotonase 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Nitrous oxide reductase, N-terminal domain Cytochrome c 11
Ribonuclease H-like RuvA domain 2-like 11
Trimeric LpxA-like enzymes PLP-dependent transferases 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidyltransferase PHP domain-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Ribosomal protein L25-like GatB/YqeY motif 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
UbiD C-terminal domain-like UbiD C-terminal domain-like 11
Glycerol-3-phosphate (1)-acyltransferase Acetyl-CoA synthetase-like 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Adenine nucleotide alpha hydrolases-like Rhodanese/Cell cycle control phosphatase 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Barwin-like endoglucanases Sporulation related repeat 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Class II aaRS and biotin synthetases GAD domain-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11

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