SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Nitratiruptor sp. SB155-2

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

482 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Nucleotide cyclase EAL domain-like 229
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 1612
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 146
PYP-like sensor domain (PAS domain) Nucleotide cyclase 96
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 92
PYP-like sensor domain (PAS domain) EAL domain-like 85
Cytochrome c Cytochrome c 85
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 83
Actin-like ATPase domain Actin-like ATPase domain 74
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 64
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 53
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 53
PLP-binding barrel Alanine racemase C-terminal domain-like 53
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 53
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 52
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 52
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 53
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 52
P-loop containing nucleoside triphosphate hydrolases Translation proteins 44
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 42
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 42
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 44
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 44
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
Homeodomain-like Ribonuclease H-like 41
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 44
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 42
PurM N-terminal domain-like PurM C-terminal domain-like 42
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 32
CheY-like C-terminal effector domain of the bipartite response regulators 31
TPR-like TPR-like 33
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 31
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 31
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 32
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 31
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 31
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 31
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 31
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 33
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 32
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 32
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 32
Alpha-L RNA-binding motif Pseudouridine synthase 31
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 31
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 32
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 32
Voltage-gated potassium channels TrkA C-terminal domain-like 22
PYP-like sensor domain (PAS domain) GAF domain-like 22
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Nucleotide-diphospho-sugar transferases RmlC-like cupins 21
HAD-like Calcium ATPase, transmembrane domain M 22
Cytochrome c C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase 22
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
CheY-like Nucleotide cyclase 22
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
Thioredoxin-like Six-hairpin glycosidases 22
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 21
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 21
MoeA N-terminal region -like MoeA C-terminal domain-like 21
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Translation proteins EF-G C-terminal domain-like 22
4Fe-4S ferredoxins 4Fe-4S ferredoxins 22
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 21
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 22
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
HD-domain/PDEase-like ACT-like 22
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 21
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 21
HD-domain/PDEase-like Nucleotidyltransferase 22
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 21
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 21
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 21
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 22
CheW-like CheW-like 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 21
Sensory domain-like Nucleotide cyclase 22
PreATP-grasp domain Rudiment single hybrid motif 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
Methyl-accepting chemotaxis protein (MCP) signaling domain Methyl-accepting chemotaxis protein (MCP) signaling domain 22
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 22
Formyltransferase FMT C-terminal domain-like 22
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 22
alpha-helical ferredoxin Nucleotide-binding domain 22
cAMP-binding domain-like "Winged helix" DNA-binding domain 21
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
Calcium ATPase, transduction domain A HAD-like 22
Triger factor/SurA peptide-binding domain-like FKBP-like 22
Nucleic acid-binding proteins RuvA domain 2-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 21
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 21
Nucleotidyltransferase ACT-like 22
vWA-like TPR-like 21
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
ACT-like ACT-like 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 21
2Fe-2S ferredoxin-like alpha-helical ferredoxin 22
Trypsin-like serine proteases PDZ domain-like 22
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 21
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Methionine synthase domain Methionine synthase activation domain-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
GroEL equatorial domain-like GroEL equatorial domain-like 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Zinc beta-ribbon DNA primase core 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Dihydropteroate synthetase-like Methionine synthase domain 11
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 11
Serine metabolism enzymes domain ACT-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
L30e-like alpha/beta knot 11
Homocysteine S-methyltransferase Methionine synthase domain 11
PGBD-like L,D-transpeptidase catalytic domain-like 11
Chorismate mutase II ACT-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Hemerythrin-like PYP-like sensor domain (PAS domain) 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Translation proteins PRC-barrel domain 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
CheY-like Methylesterase CheB, C-terminal domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
DNA clamp DNA clamp 11
PUA domain-like alpha/beta knot 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
S-adenosyl-L-methionine-dependent methyltransferases Homodimeric domain of signal transducing histidine kinase 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
YrdC/RibB RibA-like 11
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
PDZ domain-like ClpP/crotonase 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Carbamate kinase-like ACT-like 11
Barwin-like endoglucanases Sporulation related repeat 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
post-HMGL domain-like Single hybrid motif 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Nqo5-like HydB/Nqo4-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Class II aaRS and biotin synthetases GAD domain-like 11
HAMP domain-like Nucleotide cyclase 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Nucleotidyltransferase PHP domain-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 11
UROD/MetE-like UROD/MetE-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Nucleotidylyl transferase tRNA-binding arm 11
Six-hairpin glycosidases S-adenosyl-L-methionine-dependent methyltransferases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Multiheme cytochromes Multiheme cytochromes 11
Sec63 N-terminal domain-like Nucleotidyltransferase 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Nucleic acid-binding proteins GAD domain-like 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
Protein kinase-like (PK-like) WD40 repeat-like 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
Glutathione synthetase ATP-binding domain-like NAD(P)-binding Rossmann-fold domains 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Class II aaRS and biotin synthetases Translation proteins 11
NAD(P)-binding Rossmann-fold domains Citrate synthase 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Fibronectin type III Fibronectin type III 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
PreATP-grasp domain PreATP-grasp domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
CheC-like Surface presentation of antigens (SPOA) 11
SMAD/FHA domain WD40 repeat-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain Tropomyosin 11
Glycoside hydrolase/deacetylase Galactose mutarotase-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Homodimeric domain of signal transducing histidine kinase CheY-like 11
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Hemerythrin-like Nucleotide cyclase 11
Nucleic acid-binding proteins BRCT domain 11
Translation proteins ThrRS/AlaRS common domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Sensory domain-like PYP-like sensor domain (PAS domain) 11
Chorismate mutase II Periplasmic binding protein-like II 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
HAMP domain-like EAL domain-like 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
Sec63 N-terminal domain-like PHP domain-like 11
FMN-dependent nitroreductase-like FMN-dependent nitroreductase-like 11
Zn-dependent exopeptidases Fibronectin type III 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain Homodimeric domain of signal transducing histidine kinase 11
RNase III domain-like dsRNA-binding domain-like 11
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
PHP14-like Phospholipase D/nuclease 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
FliG FliG 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
HIT-like HIT-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
DNA methylase specificity domain DNA methylase specificity domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Methylesterase CheB, C-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
PUA domain-like Nucleotidylyl transferase 11
Nitrous oxide reductase, N-terminal domain Cupredoxins 11
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
DNA polymerase beta, N-terminal domain-like PHP domain-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
DNA repair protein MutS, domain III SMR domain-like 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
Phospholipase D/nuclease Phospholipase D/nuclease 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
GAF domain-like EAL domain-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
GAF domain-like Nucleotide cyclase 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
4Fe-4S ferredoxins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
PPK N-terminal domain-like PHP14-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Metalloproteases ("zincins"), catalytic domain beta-Roll 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
GIY-YIG endonuclease RuvA domain 2-like 11
Methylesterase CheB, C-terminal domain Tropomyosin 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Aldolase post-HMGL domain-like 11
ACT-like Formyltransferase 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Actin-like ATPase domain HD-domain/PDEase-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type I DNA topoisomerase 11
HMA, heavy metal-associated domain HAD-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Macro domain-like Zn-dependent exopeptidases 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Tropomyosin Homodimeric domain of signal transducing histidine kinase 11
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
HCP-like HCP-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Ribosomal protein L6 Ribosomal protein L6 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
TPR-like NTF2-like 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
HD-domain/PDEase-like TGS-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Methylesterase CheB, C-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Nitrous oxide reductase, N-terminal domain Cytochrome c 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
CheW-like CheY-like 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Cupredoxins Cytochrome c 11
beta-Roll vWA-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
4Fe-4S ferredoxins Riboflavin synthase domain-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Lysozyme-like LysM domain 11
Metallo-hydrolase/oxidoreductase Nucleotide cyclase 11
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 11
CarD-like TRCF domain-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Periplasmic binding protein-like II ACT-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
LysM domain LysM domain 11
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
PDZ domain-like PDZ domain-like 11
lambda repressor-like DNA-binding domains LexA/Signal peptidase 11
LeuD/IlvD-like Aconitase iron-sulfur domain 11
FMT C-terminal domain-like ClpP/crotonase 11
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 11
Cupredoxins Cupredoxins 11
Nqo1C-terminal domain-like Nucleotide-binding domain 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
SMAD/FHA domain Protein kinase-like (PK-like) 11
CheY-like EAL domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Translation proteins Translation proteins 11
(Trans)glycosidases Glycosyl hydrolase domain 11
TGS-like ACT-like 11
Formyltransferase ClpP/crotonase 11
DNA polymerase beta, N-terminal domain-like Sec63 N-terminal domain-like 11
Methylesterase CheB, C-terminal domain Homodimeric domain of signal transducing histidine kinase 11
Nqo1C-terminal domain-like alpha-helical ferredoxin 11
Origin of replication-binding domain, RBD-like P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Sec-C motif NTF2-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
HisI-like all-alpha NTP pyrophosphatases 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
PIN domain-like Ribonuclease H-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Cytochrome c Thioredoxin-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
Nucleotidyltransferase TGS-like 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
YjeF N-terminal domain-like Ribokinase-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
PHP domain-like AF1531-like 11
Ribonuclease H-like DNA/RNA polymerases 11
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
PP2C-like Protein kinase-like (PK-like) 11
Ribokinase-like Nucleotidylyl transferase 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
HlyD-like secretion proteins HlyD-like secretion proteins 11
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 11
S-adenosyl-L-methionine-dependent methyltransferases Tropomyosin 11
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Thiolase-like Thiolase-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
UbiD C-terminal domain-like UbiD C-terminal domain-like 11
Tropomyosin ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Hemerythrin-like EAL domain-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Acyl-CoA N-acyltransferases (Nat) 11
CBS-domain pair MgtE membrane domain-like 11
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 11
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 11
CheY-like CheY-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
PIN domain-like DNA/RNA polymerases 11
TT1751-like TT1751-like 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
RuvA domain 2-like BRCT domain 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 11
Single hybrid motif CoA-dependent acyltransferases 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Zinc beta-ribbon Zinc beta-ribbon 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
Aldolase Single hybrid motif 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
cAMP-binding domain-like CBS-domain pair 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
MgtE N-terminal domain-like CBS-domain pair 11
Methylesterase CheB, C-terminal domain Chemotaxis receptor methyltransferase CheR, N-terminal domain 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
beta-Roll beta-Roll 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11

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