SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Actinobacillus pleuropneumoniae serovar 5b str. L20

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

525 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2511
Actin-like ATPase domain Actin-like ATPase domain 134
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 111
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 96
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 94
P-loop containing nucleoside triphosphate hydrolases Translation proteins 76
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 75
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
Homeodomain-like Homeodomain-like 61
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 63
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 55
P-loop containing nucleoside triphosphate hydrolases MOP-like 51
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 51
CheY-like C-terminal effector domain of the bipartite response regulators 51
PurM N-terminal domain-like PurM C-terminal domain-like 52
ACT-like ACT-like 55
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 52
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 42
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 41
Alpha-L RNA-binding motif Pseudouridine synthase 41
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 42
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 43
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 43
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 41
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 42
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
Nucleic acid-binding proteins Nucleic acid-binding proteins 43
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 41
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 41
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
Thioredoxin-like GST C-terminal domain-like 41
PreATP-grasp domain Rudiment single hybrid motif 31
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 33
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 33
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 32
Nucleic acid-binding proteins RuvA domain 2-like 33
HD-domain/PDEase-like Nucleotidyltransferase 32
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 31
Translation proteins EF-G C-terminal domain-like 33
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 32
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Triger factor/SurA peptide-binding domain-like FKBP-like 33
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 31
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 31
CBS-domain pair FAD-binding/transporter-associated domain-like 31
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 33
DNA methylase specificity domain DNA methylase specificity domain 31
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
TrkA C-terminal domain-like TrkA C-terminal domain-like 32
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 32
MetI-like MetI-like 32
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 32
Nucleotidyltransferase ACT-like 32
HD-domain/PDEase-like ACT-like 32
(Trans)glycosidases Glycosyl hydrolase domain 33
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 31
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
PTS system fructose IIA component-like PTS IIb component 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Nucleotidyltransferase TGS-like 21
L30e-like alpha/beta knot 22
cAMP-binding domain-like "Winged helix" DNA-binding domain 21
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
beta-Roll beta-Roll 22
GroES-like NAD(P)-binding Rossmann-fold domains 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 22
PLP-binding barrel Alanine racemase C-terminal domain-like 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 22
HD-domain/PDEase-like TGS-like 21
E set domains (Trans)glycosidases 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Adhesin YadA, collagen-binding domain Adhesin YadA, collagen-binding domain 22
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 22
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Lysozyme-like beta-lactamase/transpeptidase-like 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
"Winged helix" DNA-binding domain PLP-dependent transferases 21
PDZ domain-like PDZ domain-like 22
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
Trypsin-like serine proteases PDZ domain-like 22
Adhesin YadA, collagen-binding domain Pili subunits 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 22
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 22
Enolase N-terminal domain-like Enolase C-terminal domain-like 21
TGS-like ACT-like 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 21
Cupredoxins Cupredoxins 22
OMPA-like OMPA-like 21
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
Single hybrid motif CoA-dependent acyltransferases 22
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 22
Carbamate kinase-like ACT-like 22
OMPA-like OmpA-like 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 21
E set domains Glycosyl hydrolase domain 22
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Tex N-terminal region-like Ribonuclease H-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
PTS system IIB component-like Phoshotransferase/anion transport protein 11
TPR-like TPR-like 11
PTS system IIB component-like PTS system IIB component-like 11
Radical SAM enzymes Heme iron utilization protein-like 11
Carbamate kinase-like NAD(P)-binding Rossmann-fold domains 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Homodimeric domain of signal transducing histidine kinase CheY-like 11
TPR-like C-terminal effector domain of the bipartite response regulators 11
Enolase C-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Ribulose-phoshate binding barrel Ribulose-phoshate binding barrel 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
"Winged helix" DNA-binding domain C-terminal domain of arginine repressor 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Zn-dependent exopeptidases LysM domain 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Pseudouridine synthase PUA domain-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
HPr-like HPr-like 11
RuvA domain 2-like JAB1/MPN domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Porins ABC transporter transmembrane region 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 11
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 11
GIY-YIG endonuclease RuvA domain 2-like 11
RuvA domain 2-like BRCT domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
Homeodomain-like SIS domain 11
Periplasmic binding protein-like II Lysozyme-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Glutamine synthetase/guanido kinase Glutathione synthetase ATP-binding domain-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Ribbon-helix-helix Replication modulator SeqA, C-terminal DNA-binding domain 11
H-NS histone-like proteins H-NS histone-like proteins 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 11
HAD-like Calcium ATPase, transmembrane domain M 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Chorismate mutase II NAD(P)-binding Rossmann-fold domains 11
ACT-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
THUMP domain-like Rhodanese/Cell cycle control phosphatase 11
"Winged helix" DNA-binding domain MukF C-terminal domain-like 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
YajQ-like YajQ-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Chorismate mutase II 6-phosphogluconate dehydrogenase C-terminal domain-like 11
Ribonuclease H-like RuvA domain 2-like 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
Translation proteins PRC-barrel domain 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
ClpP/crotonase ClpP/crotonase 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
PurS-like Class I glutamine amidotransferase-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Ribokinase-like Nucleotidylyl transferase 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
Periplasmic binding protein-like I Homeodomain-like 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
TGS-like ThrRS/AlaRS common domain 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
HesB-like domain Fe-S cluster assembly (FSCA) domain-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Macro domain-like Zn-dependent exopeptidases 11
"Winged helix" DNA-binding domain Actin-like ATPase domain 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
lambda repressor-like DNA-binding domains Nucleotidylyl transferase 11
RNase III domain-like dsRNA-binding domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
Nucleic acid-binding proteins GAD domain-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Flavoproteins Riboflavin synthase domain-like 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
GroEL equatorial domain-like GroEL equatorial domain-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
Nqo1 FMN-binding domain-like alpha-helical ferredoxin 11
CarD-like TRCF domain-like 11
PUA domain-like alpha/beta knot 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
post-HMGL domain-like Single hybrid motif 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Cytidine deaminase-like Cytidine deaminase-like 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Nucleotide-diphospho-sugar transferases P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
HMA, heavy metal-associated domain HAD-like 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
MOSC N-terminal domain-like PK beta-barrel domain-like 11
Homeodomain-like Ribonuclease H-like 11
HIT-like HIT-like 11
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
ABC transporter involved in vitamin B12 uptake, BtuC ABC transporter involved in vitamin B12 uptake, BtuC 11
YrdC/RibB RibA-like 11
Acylphosphatase/BLUF domain-like Actin-like ATPase domain 11
HisI-like all-alpha NTP pyrophosphatases 11
Multiheme cytochromes Cytochrome c 11
Phoshotransferase/anion transport protein HPr-like 11
MetI-like P-loop containing nucleoside triphosphate hydrolases 11
beta-Galactosidase/glucuronidase domain Galactose mutarotase-like 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Single hybrid motif Single hybrid motif 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Fibronectin type III Pectin lyase-like 11
UROD/MetE-like UROD/MetE-like 11
GroES-like GroES-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Carbamate kinase-like PUA domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
TGS-like Class II aaRS and biotin synthetases 11
lambda repressor-like DNA-binding domains P-loop containing nucleoside triphosphate hydrolases 11
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
YrdC/RibB Actin-like ATPase domain 11
HRDC-like HRDC-like 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
PDZ domain-like ClpP/crotonase 11
Translation proteins "Winged helix" DNA-binding domain 11
Formyltransferase FMT C-terminal domain-like 11
Translation proteins ThrRS/AlaRS common domain 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 11
Porins P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Chorismate mutase II ACT-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
FucI/AraA N-terminal and middle domains FucI/AraA C-terminal domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Histidine-containing phosphotransfer domain, HPT domain 11
Carbamate kinase-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
Aldolase Single hybrid motif 11
OmpH-like OmpH-like 11
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Hsp33 domain HSP33 redox switch-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Zinc beta-ribbon Zinc beta-ribbon 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 11
Adenine nucleotide alpha hydrolases-like Rhodanese/Cell cycle control phosphatase 11
PurS-like PurM C-terminal domain-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 11
Ribonuclease H-like HRDC-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Phospholipase D/nuclease Phospholipase D/nuclease 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
(Trans)glycosidases Galactose mutarotase-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Nucleotidylyl transferase tRNA-binding arm 11
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Thiolase-like Thiolase-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
THUMP domain-like Adenine nucleotide alpha hydrolases-like 11
"Winged helix" DNA-binding domain GAF domain-like 11
Galactose-binding domain-like (Trans)glycosidases 11
FAD-linked oxidoreductase ALDH-like 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
NTF2-like Sec-C motif 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Phoshotransferase/anion transport protein Phoshotransferase/anion transport protein 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
Aldolase post-HMGL domain-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
PheT/TilS domain Putative DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
HAD-like Ribosomal protein S5 domain 2-like 11
DNA primase core DNA primase DnaG, C-terminal domain 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Ribosomal protein L6 Ribosomal protein L6 11
Cytochrome c Cytochrome c 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Bacterial muramidases Lysozyme-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Tex N-terminal region-like RuvA domain 2-like 11
TGS-like Class II aaRS ABD-related 11
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 11
Galactose-binding domain-like Galactose mutarotase-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal effector domain of the bipartite response regulators 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 11
Nucleic acid-binding proteins PheT/TilS domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Class II aaRS and biotin synthetases Translation proteins 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain "Winged helix" DNA-binding domain 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Ribonuclease H-like DNA/RNA polymerases 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 11
Subtilisin-like Autotransporter 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Metalloproteases ("zincins"), catalytic domain Acyl-CoA N-acyltransferases (Nat) 11
PurS-like PurM N-terminal domain-like 11
Chorismate mutase II Periplasmic binding protein-like II 11
Homeodomain-like TrpR-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Clavaminate synthase-like S-adenosyl-L-methionine-dependent methyltransferases 11
PIN domain-like Ribonuclease H-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
HlyD-like secretion proteins HlyD-like secretion proteins 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Nucleotidylyl transferase P-loop containing nucleoside triphosphate hydrolases 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Periplasmic binding protein-like II GlnB-like 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
Thioredoxin-like TPR-like 11
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
CheY-like Histidine-containing phosphotransfer domain, HPT domain 11
MalF N-terminal region-like MetI-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
PIN domain-like DNA/RNA polymerases 11
Zinc beta-ribbon DNA primase core 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Calcium ATPase, transduction domain A HAD-like 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
PurS-like FGAM synthase PurL, linker domain 11
PK beta-barrel domain-like PK C-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Periplasmic binding protein-like II ACT-like 11
P-loop containing nucleoside triphosphate hydrolases Acyl-CoA N-acyltransferases (Nat) 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 11
beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain 11
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 11
DNA-glycosylase Nudix 11
ALDH-like Dehydroquinate synthase-like 11
SIS domain CBS-domain pair 11
RuvA domain 2-like RuvA domain 2-like 11
DNA clamp DNA clamp 11
Translation proteins Translation proteins 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
P-loop containing nucleoside triphosphate hydrolases TPR-like 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
E set domains E set domains 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
Chaperone J-domain HSP40/DnaJ peptide-binding domain 11
Class II aaRS and biotin synthetases GAD domain-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 11
Nucleic acid-binding proteins BRCT domain 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11

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